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The Ellis Martin Report: Interview with Ken Aldrich of International Stem Cell Corp.
Ken Aldrich of International Stem Cell Corp (ISCO.OB) on the Present and Future of Stem Cell Research and Applications
The Ellis Martin Report: International Stem Cell Corporation trades under the symbol ISCO.OB on the Over the Counter Bulletin Board and is based in Carlsbad, California where I have the pleasure of interviewing Executive Chairman, Kenneth Aldrich. International Stem Cell has developed a process to derive stem cells similar to Embryonic Stem Cells without the need for fertilized embryos and with minimal exposure to non-human cells. These factors provide ISCO a unique leadership role in the field of regene...
Source: International Stem Cell Corporation - August 8, 2011 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology science health medicine parthenogenesis stem cell stem cell bank pluripotent international stem cell corporation parkinsons Source Type: podcasts
The Difference Between Adult Stem Cells and Embryonic Stem Cells
This is Ken Aldrich. I am Chairman of International Stem Cell Corporation and thought I’d talk for just a minute, or maybe a couple of minutes, about the different kinds of stem cells. People are always asking, “What’s the difference between an adult stem cell and an embryonic stem cell?” Let me try to make this as simple as possible. Adult stem cells are those that are derived from the human body any time after the first, probably, week or two of development of the fetus in the womb. So, cells that come from cord blood, or cells that come from embryonic tissue as well as cells that come from an adult hum...
Source: International Stem Cell Corporation - April 16, 2009 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology health medicine parthenogenesis stem cell bank pluripotent international stem cell corporation alzheimers parkinsons leukemia vectors Source Type: podcasts
ISCO and Absorption Sytems to Commercialize Stem Cell Derived Human Corneal Tissue for Drug Test
International Stem Cell Corporation (OTCBB:ISCO (www.internationalstemcell.com), the first company to perfect a method of creating human “parthenogenetic” stem cells from unfertilized eggs, has formed a partnership with Absorption Systems to utilize ISCO’s parthenogenetic stem cell-derived human corneal tissue to measure drug disposition, drug safety and drug-drug interactions. The collaboration between the companies is focused on using Absorption Systems’ know how in creating in vitro assay systems to develop a superior method of testing drugs that will also reduce the use of laboratory animals curren...
Source: International Stem Cell Corporation - November 25, 2008 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology science health medicine parthenogenesis stem cell Source Type: podcasts
International Stem Cell Corporation Announces a Manufacturing and Supply Agreement with Millipore Co
International Stem Cell (OTCBB:ISCO) announced today it has entered into a worldwide distribution agreement with Millipore Corporation (NYSE: MIL) to manufacture living cells and cell culture products to be sold through Millipore’s distribution network.
“To work with a company such as Millipore that has sales of over $1.5 billion and is known throughout the world is a wonderful opportunity for ISCO. This partnership will lead to a significant expansion in ISCO’s revenue generation through the manufacture of high quality cells and cell culture products. Millipore is a leader in the life science industry, with a strong...
Source: International Stem Cell Corporation - September 25, 2008 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology science health medicine parthenogenesis stem cell Source Type: podcasts
The Ellis Martin Report: Interview with International Stem Cell Corporation’s Founder/Co-Chairman
TEMR: Welcome to The Ellis Martin Report. I’m Bob Lange. We’re talking with Kenneth Aldrich, Executive Chairman of International Stem Cell Corporation, trading on the OTC Market with the symbol ISCO. International Stem Cell Corporation has been one of the most exciting companies trading in the biotech sector with respect to non-embryonic stem cell development. They have a proprietary process and commercial products that give them a tremendous edge in the marketplace. Ken welcome back to the show. I understand there’s a lot going on at International Stem Cell Corporation. Can you give us at least a portion...
Source: International Stem Cell Corporation - October 21, 2011 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology stem cell international stem cell corporation cosmeceutical Lifeline Cell Technology Lifeline Skin Care stem cell reagent stem cell skin care Source Type: podcasts
The Ellis Martin Report: Interview with Ken Aldrich of International Stem Cell Corp.
Ken Aldrich of International Stem Cell Corp (ISCO.OB) on the Present and Future of Stem Cell Research and Applications
The Ellis Martin Report: International Stem Cell Corporation trades under the symbol ISCO.OB on the Over the Counter Bulletin Board and is based in Carlsbad, California where I have the pleasure of interviewing Executive Chairman, Kenneth Aldrich. International Stem Cell has developed a process to derive stem cells similar to Embryonic Stem Cells without the need for fertilized embryos and with minimal exposure to non-human cells. These factors provide ISCO a unique leadership role in the field of regene...
Source: International Stem Cell Corporation - August 8, 2011 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology science health medicine parthenogenesis stem cell stem cell bank pluripotent international stem cell corporation parkinsons Source Type: podcasts
The Difference Between Adult Stem Cells and Embryonic Stem Cells
This is Ken Aldrich. I am Chairman of International Stem Cell Corporation and thought I’d talk for just a minute, or maybe a couple of minutes, about the different kinds of stem cells. People are always asking, “What’s the difference between an adult stem cell and an embryonic stem cell?” Let me try to make this as simple as possible. Adult stem cells are those that are derived from the human body any time after the first, probably, week or two of development of the fetus in the womb. So, cells that come from cord blood, or cells that come from embryonic tissue as well as cells that come from an adult hum...
Source: International Stem Cell Corporation - April 16, 2009 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology health medicine parthenogenesis stem cell bank pluripotent international stem cell corporation alzheimers parkinsons leukemia vectors Source Type: podcasts
ISCO and Absorption Sytems to Commercialize Stem Cell Derived Human Corneal Tissue for Drug Test
International Stem Cell Corporation (OTCBB:ISCO (www.internationalstemcell.com), the first company to perfect a method of creating human “parthenogenetic” stem cells from unfertilized eggs, has formed a partnership with Absorption Systems to utilize ISCO’s parthenogenetic stem cell-derived human corneal tissue to measure drug disposition, drug safety and drug-drug interactions. The collaboration between the companies is focused on using Absorption Systems’ know how in creating in vitro assay systems to develop a superior method of testing drugs that will also reduce the use of laboratory animals curren...
Source: International Stem Cell Corporation - November 25, 2008 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology science health medicine parthenogenesis stem cell Source Type: podcasts
International Stem Cell Corporation Announces a Manufacturing and Supply Agreement with Millipore Co
International Stem Cell (OTCBB:ISCO) announced today it has entered into a worldwide distribution agreement with Millipore Corporation (NYSE: MIL) to manufacture living cells and cell culture products to be sold through Millipore’s distribution network.
“To work with a company such as Millipore that has sales of over $1.5 billion and is known throughout the world is a wonderful opportunity for ISCO. This partnership will lead to a significant expansion in ISCO’s revenue generation through the manufacture of high quality cells and cell culture products. Millipore is a leader in the life science industry, with a strong...
Source: International Stem Cell Corporation - September 25, 2008 Category: Stem Cells Authors: internationalstemcell Tags: biotechnology science health medicine parthenogenesis stem cell Source Type: podcasts
Significance of Biotic Factors in Mesenchymal Stem Cell Fate in Regenerative Medicine.
Abstract
Stem and progenitor cell research is a complex and very exciting field that promises fantastic curative discoveries in numerous areas from cancer to diabetes to regenerative medicine. The use of biotic factors or growth factors has played an essential role in the development of stem cell research. These biologically active components have been administered into stem cells either to improve or maintain the stem cell proliferation, or to encourage controlled differentiation into more defined cell types. Small molecules like 6-Bromoindirubin-3´-oxime (BIO), cardiogenol-C, etc can really help stem cell resea...
Source: Current Stem Cell Research and Therapy - May 7, 2014 Category: Stem Cells Authors: Baadhe RR, Mekala NK, Potumarthi R Tags: Curr Stem Cell Res Ther Source Type: research
Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling.
Abstract
Airways are exposed to myriad environmental and damaging agents such as reactive oxygen species (ROS), which also have physiological roles as signaling molecules that regulate stem cell function. However, the functional significance of both steady and dynamically changing ROS levels in different stem cell populations, as well as downstream mechanisms that integrate ROS sensing into decisions regarding stem cell homeostasis, are unclear. Here, we show in mouse and human airway basal stem cells (ABSCs) that intracellular flux from low to moderate ROS levels is required for stem cell self-renewal and prolife...
Source: Cell Stem Cell - June 18, 2014 Category: Stem Cells Authors: Paul MK, Bisht B, Darmawan DO, Chiou R, Ha VL, Wallace WD, Chon AT, Hegab AE, Grogan T, Elashoff DA, Alva-Ornelas JA, Gomperts BN Tags: Cell Stem Cell Source Type: research
Dental Stem Cell in Tooth Development and Advances of Adult Dental Stem Cell in Regenerative Therapies.
Abstract
Stem cell-based therapies are considered as a promising treatment for many clinical diseases such as Alzheimer's disease, Parkinson's disease, spinal cord injury, and so on. However, the ideal stem cell for stem cell-based therapy still remains to be elucidated. In the past decades, several types of stem cells have been isolated from teeth, including dental pulp stem cells, stem cells from human exfoliated deciduous teeth, periodontal ligament stem cells, dental follicle progenitor stem cells and stem cells from apical papilla, which may be a good stem cell type for stem cell-based therapy in certain dise...
Source: Current Stem Cell Research and Therapy - October 2, 2014 Category: Stem Cells Authors: Tan J, Xu X, Lin J, Fan L, Zheng Y, Kuang W Tags: Curr Stem Cell Res Ther Source Type: research
The endocrine regulation of stem cells: physiological importance and pharmacological potentials for cell-based therapy.
Abstract
Throughout life, different types of stem cells participate in tissue generation, maintenance, plasticity, and repair. Their abilities to secrete growth factors, to proliferate and differentiate into several cell lineages, and to migrate and home into the damaged tissues have made them attractive candidates for cell therapy and tissue engineering applications. Normal stem cell function is tied to the cell-intrinsic mechanisms and extrinsic signals derived from the surrounding microenvironment or circulation. Understanding the regulatory signals that govern stem cell functions is essential in order to have ...
Source: Current Stem Cell Research and Therapy - September 4, 2015 Category: Stem Cells Authors: Ghorbani A, Naderi-Meshkin H Tags: Curr Stem Cell Res Ther Source Type: research
Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor Pools
Publication date: 12 January 2016 Source:Stem Cell Reports, Volume 6, Issue 1 Author(s): Nina Akrap, Daniel Andersson, Eva Bom, Pernilla Gregersson, Anders Ståhlberg, Göran Landberg The identification of breast cancer cell subpopulations featuring truly malignant stem cell qualities is a challenge due to the complexity of the disease and lack of general markers. By combining extensive single-cell gene expression profiling with three functional strategies for cancer stem cell enrichment including anchorage-independent culture, hypoxia, and analyses of low-proliferative, label-retaining cells derived from mammosphe...
Source: Stem Cell Reports - January 13, 2016 Category: Stem Cells Source Type: research
Concise Review: Stem Cell Microenvironment on a Chip: Current Technologies for Tissue Engineering and Stem Cell Biology
Stem cells have huge potential in many therapeutic areas. With conventional cell culture methods, however, it is difficult to achieve in vivo-like microenvironments in which a number of well-controlled stimuli are provided for growing highly sensitive stem cells. In contrast, microtechnology-based platforms offer advantages of high precision, controllability, scalability, and reproducibility, enabling imitation of the complex physiological context of in vivo. This capability may fill the gap between the present knowledge about stem cells and that required for clinical stem cell-based therapies. We reviewed the various type...
Source: Stem Cells Translational Medicine - October 27, 2015 Category: Stem Cells Authors: Park, D., Lim, J., Park, J. Y., Lee, S.-H. Tags: Concise Review, Tissue Engineering and Regenerative Medicine, Mesenchymal Stem Cells Source Type: research
