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Control of a Reassortant Pandemic 2009 H1N1 Influenza Virus Outbreak in an Intensive Swine Breeding Farm: Effect of Vaccination and Enhanced Farm Management Practices
Conclusions Although our study design was sub-optimal for evaluating the effectiveness of the intervention, we provided suggestive evidence that H1N1pdm-targeted vaccination in sows/gilts, enhanced biosecurity, lengthening of weaning cycles, and constrains in cross-fostering of piglets may prove useful in controlling a reassortant H1N1pdm outbreak in an intensive swine breeding farm without possibility of applying an all-in/all-out system. Maternally-derived immunity was elicited and further virus circulation in piglets dropped to undetectable levels, while keeping farm productivity at full. The present field study also su...
Source: PLOS Currents Outbreaks - April 13, 2015 Category: Epidemiology Authors: Lapo Mughini-Gras Source Type: research

Cardiovascular Parameters in a Swine Model of Normobaric Hypoxia Treated With 5-Hydroxymethyl-2-Furfural (5-HMF)
Conclusion: 5-HMF treatment decreased P50, improved SaO2, and mitigated increases in PAP in this swine model of NH. Introduction The reduction of barometric pressure at altitude is associated with reduced partial pressure of ambient Oxygen (PO2). With lower ambient PO2, it can be anticipated that alveolar (PAO2), arterial O2 (PaO2) and blood O2 content (CaO2) will decrease accordingly, resulting in a widely recognized decrease in maximal O2 consumption (VO2) (Dill and Adams, 1972; Lucas et al., 2011). In humans, with acute exposure to altitude, maximal VO2 decrements are measurable at elevations even as low as 580 ...
Source: Frontiers in Physiology - April 17, 2019 Category: Physiology Source Type: research

The functional vascular anatomy of the swine for research
CONCLUSIONS: Swine are utilized in broad-reaching fields for preclinical research. While many similarities between human and swine vasculature exist, there are important differences to consider when conducting and interpreting research. This review article highlights these differences and presents accompanying images to inform clinicians gaining experience in swine research.PMID:33813971 | DOI:10.1177/1708538121996500
Source: Vascular - April 5, 2021 Category: Surgery Authors: Joseph Edwards Hossam Abdou Neerav Patel Marta J Madurska Kelly Poe Janet E Bonin Michael J Richmond Todd E Rasmussen Jonathan J Morrison Source Type: research

Development of a common peroneal nerve injury model in domestic swine for the study of translational neuropathic pain treatments
CONCLUSIONS: In a neuropathic pain model in domestic swine, the authors demonstrated that CPNI induces demyelination of the common peroneal nerve, which the authors hypothesize is responsible for the resulting allodynic pain behavior. As the anatomical features of domestic swine resemble those of humans more closely than previously used rat and mouse models, utilizing this swine model, which is to the authors' knowledge the first of its kind, will aid in the translation of experimental treatments to clinical trials.PMID:33862596 | DOI:10.3171/2020.9.JNS202961
Source: Journal of Neurosurgery - April 16, 2021 Category: Neurosurgery Authors: Abigail Hellman Teresa Maietta Alicia Clum Kanakaharini Byraju Nataly Raviv Michael D Staudt Erin Jeannotte Julia Nalwalk Sophie Belin Yannick Poitelon Julie G Pilitsis Source Type: research

Diarrheagenic Escherichia coli pathotypes isolated from a swine farm in a region of Morelos state, Mexico
CONCLUSIONS: In this study, four different E. coli pathotypes were found among swine colonized by E. coli in this farm. Thus, these swine are reservoirs for these virulent bacteria and there is potential risk of causing diarrhea in swine and in the population consuming the meat.PMID:33984213 | DOI:10.21149/11268
Source: Salud Publica de Mexico - May 13, 2021 Category: Epidemiology Authors: Elsa Mar ía Tamayo-Legorreta Alejandro Garc ía-Radilla Eduardo Moreno-V ázquez Fabi án Téllez-Figueroa Celia M Alpuche-Aranda Source Type: research

A Review of the Current Status of Relevant Zoonotic Pathogens in Wild Swine (Sus scrofa) Populations: Changes Modulating the Risk of Transmission to Humans
Summary Many wild swine populations in different parts of the World have experienced an unprecedented demographic explosion that may result in increased exposure of humans to wild swine zoonotic pathogens. Interactions between humans and wild swine leading to pathogen transmission could come from different ways, being hunters and game professionals the most exposed to acquiring infections from wild swine. However, increasing human settlements in semi‐natural areas, outdoor activities, socio‐economic changes and food habits may increase the rate of exposure to wild swine zoonotic pathogens and to potentially emerging pa...
Source: Transboundary and Emerging Diseases - May 8, 2015 Category: Veterinary Research Authors: F. Ruiz‐Fons Tags: Review Article Source Type: research

Prevalence of Influenza A Virus in Exhibition Swine during Arrival at Agricultural Fairs
Summary The exhibition swine at agricultural fairs provides a critical human–swine interface that allows for the bidirectional transmission of influenza A virus (IAV). Previous IAV surveillance at the end of fairs has resulted in frequent detection of IAV‐infected swine; little is known, however, about the frequency with which swine arrive at fairs already infected with IAV. We investigated the IAV prevalence among exhibition swine entering fairs to better understand the epidemiology of IAV in this unique human–swine interface. In 2014, snout wipes were collected from 3547 swine during the first day of nine agricultu...
Source: Zoonoses and Public Health - January 11, 2016 Category: Infectious Diseases Authors: N. Bliss, S. W. Nelson, J. M. Nolting, A. S. Bowman Tags: Original Article Source Type: research