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Development and evaluation of multi-epitope protein p72 (MeP72) for the serodiagnosis of African swine fever
Acta Virol. 2021;65(3):273-278. doi: 10.4149/av_2021_304.ABSTRACTAfrican swine fever (ASF) is an acute and severe infectious disease that seriously endangers the global porcine industry. In order to develop ASF serodiagnostic reagents with high specificity and sensitivity, in the present study, the antigenic epitopes of P72 protein of African swine fever virus (ASFV) were analyzed, and the ASFV multi-epitope fusion gene MeP72 in tandem with the dominant linear epitopes was constructed. The recombinant multi-epitope fusion MeP72 (reMeP72) was prepared in Escherichia coli. A colloidal gold-based immunochromatographic assay (...
Source: Acta Virologica - September 27, 2021 Category: Infectious Diseases Authors: Xingxing Zhang Jing Guo Lixia Wang Zhiyuan Li Yucheng Liu Lulu Tian Chencheng Xiao Yanfang Li Xuepeng Cai Qingling Meng Jun Qiao Source Type: research