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Flu Season Now As Bad As 2009 Swine Flu
NEW YORK (AP) — The flu has further tightened its grip on the U.S. This season is now as bad as the swine flu epidemic nine years ago. A government report out Friday shows 1 of every 13 visits to the doctor last week was for fever, cough and other symptoms of the flu. That ties the highest level seen in the U.S. during swine flu in 2009. And it surpasses every winter flu season since 2003, when the government changed the way it measures flu. “I wish that there were better news this week, but almost everything we’re looking at is bad news,” said Dr. Anne Schuchat, acting director of the Centers for Disea...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 9, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Flu Swine Flu Source Type: news

Co-infection status of classical swine fever virus (CSFV), porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circoviruses (PCV2 and PCV3) in eight regions of China from 2016 to 2018.
In this study, we evaluated the co-infection of these four viruses in 159 pigs collected from 63 herds in eight regions of China from 2016 to 2018. CSFV, PRRSV, PCV2 and PCV3 were detected in 14, 56, 43 and 4 of the pigs, respectively. The percentage of singular infections was 32.71%, while the percentages of dual infections and multiple infections were 15.72% and 3.15%, respectively. The E2 of CSFV, ORF5 of PRRSV, ORF2s of PCV2 and PCV3 from all positive samples were determined and used for phylogenetic analyses. E2-based phylogenetic tree showed that all 14 CSFVs identified in this study belong to 2.1b subtype. ORF5-base...
Source: Infection, Genetics and Evolution - December 17, 2018 Category: Genetics & Stem Cells Authors: Chen N, Huang Y, Ye M, Li S, Xiao Y, Cui B, Zhu J Tags: Infect Genet Evol Source Type: research

Classical swine fever: challenges for the emerging swine sector in Bhutan
AbstractGiven the importance of pork in the Bhutanese diet and to enhance food security, the Government of Bhutan has generated policies to promote development of the swine sector in the country. One of the main threats to swine farming is classical swine fever (CSF), a transboundary disease of wild and domestic swine thought to be enzootic in the country. In 2018, three outbreaks of CSF were notified in Bhutan. The type of animals, their vaccine status, and the aftermath of these outbreaks highlight the interplay of epidemiological and context-specific factors that may result in CSF undermining the emerging Bhutanese swin...
Source: Tropical Animal Health and Production - March 15, 2020 Category: Veterinary Research Source Type: research

Development a multiplex RT-PCR assay for simultaneous detection of African swine fever virus, classical swine fever virus and atypical porcine pestivirus.
This study provides an important tool for rapid detection and accurate diagnosis of ASFV, CSFV and APPV. PMID: 33127443 [PubMed - as supplied by publisher]
Source: Journal of Virological Methods - October 27, 2020 Category: Virology Authors: Liu H, Shi K, Sun W, Zhao J, Yin Y, Si H, Qu S, Lu W Tags: J Virol Methods Source Type: research

Sensors, Vol. 22, Pages 708: Photonic Label-Free Biosensors for Fast and Multiplex Detection of Swine Viral Diseases
Athnasios I. Gelasakis Ioannis Bossis Gyula Balka Lilla Dénes Maciej Frant Lapo Nannucci Matteo Bonasso Alessandro Giusti Amadeu Griol In this paper we present the development of photonic integrated circuit (PIC) biosensors for the label-free detection of six emerging and endemic swine viruses, namely: African Swine Fever Virus (ASFV), Classical Swine Fever Virus (CSFV), Porcine Reproductive and Respiratory Syndrome Virus (PPRSV), Porcine Parvovirus (PPV), Porcine Circovirus 2 (PCV2), and Swine Influenza Virus A (SIV). The optical biosensors are based on evanescent wave technology and, in particular...
Source: Sensors - January 18, 2022 Category: Biotechnology Authors: Maribel G ómez-Gómez Carles S ánchez Sergio Peransi David Zurita Laurent Bellieres Sara Recuero Manuel Rodrigo Santiago Sim ón Alessandra Camarca Alessandro Capo Maria Staiano Antonio Varriale Sabato D ’Auria Georgios Manessis Athnasios I. Gelasakis Tags: Article Source Type: research

Prevalence of Campylobacter spp., Salmonella spp., Listeria monocytogenes, and hepatitis E virus in swine livers collected at an abattoir.
Abstract We investigated the prevalence of Campylobacter spp., Salmonella spp., Listeria monocytogenes, and hepatitis E virus (HEV) in swine liver. We collected swine livers from 110 pigs at an abattoir from September 2010 to March 2011. Pathogens were detected in the liver samples of 19 (17.3%) pigs. Campylobacter spp. were isolated from the liver samples of 14 (12.7%) pigs. In 10 of the 14 Campylobacter-positive pigs, bacteria were present in the internal regions of the liver. Salmonella spp. and L. monocytogenes were detected in the liver samples of 5 (4.5%) pigs and 1 (1%) pig, respectively. No HEV was detecte...
Source: Japanese Journal of Infectious Diseases - May 25, 2013 Category: Infectious Diseases Authors: Sasaki Y, Haruna M, Murakami M, Hayashida M, Ito K, Noda M, Yamada Y Tags: Jpn J Infect Dis Source Type: research

Distribution of antibiotic resistance genes (ARGs) in anaerobic digestion and land application of swine wastewater.
Abstract Swine farm and the adjacent farmland are hot spots of ARGs. However, few studies have investigated the on-site occurrence of ARGs distributed in the process of anaerobic digestion (AD) followed by land application of swine wastewater. Two typical swine farms, in southern and northern China respectively, with AD along with land application were explored on ARG distributions. ARGs were highly abundant in raw swine wastewater, AD effectively reduced the copy number of all detected ARGs (0.21-1.34 logs removal), but the relative abundance with different resistance mechanisms showed distinctive variation trend...
Source: Environmental Pollution - March 29, 2016 Category: Environmental Health Authors: Sui Q, Zhang J, Chen M, Tong J, Wang R, Wei Y Tags: Environ Pollut Source Type: research

A multiplex reverse transcription PCR and automated electronic microarray assay for detection and differentiation of seven viruses affecting swine
This study describes the development and initial evaluation of a multiplex reverse transcription (RT)‐PCR and novel accompanying automated electronic microarray assay for simultaneous detection and differentiation of seven important viruses that affect swine (foot‐and‐mouth disease virus [FMDV], swine vesicular disease virus [SVDV], vesicular exanthema of swine virus [VESV], African swine fever virus [ASFV], classical swine fever virus [CSFV], porcine respiratory and reproductive syndrome virus [PRRSV] and porcine circovirus type 2 [PCV2]). The novel electronic microarray assay utilizes a single, user‐friendly inst...
Source: Transboundary and Emerging Diseases - November 30, 2017 Category: Veterinary Research Authors: A. Erickson, M. Fisher, T. Furukawa ‐Stoffer, A. Ambagala, D. Hodko, J. Pasick, D. P. King, C. Nfon, R. Ortega Polo, O. Lung Tags: ORIGINAL ARTICLE Source Type: research

αvβ3 Integrin and fibronectin expressions and their relation to estrogen and progesterone during placentation in swine.
Abstract Mammalian pregnancy requires specific interactions between the conceptus and its mother that involve the endocrine system and adhesion molecules. The relation between adhesion molecules and their ligands at the fetal-maternal interface is crucial for developing a successful implantation. Progesterone (P4) and estrogen (E2) secreted by the porcine conceptus are required for the relation to be established. We investigated the expression of αvβ3 integrin and its ligand, fibronectin (FN), at the placental interface, and E2 and P4 concentrations in both serum and maternal and fetal placental extracts during ...
Source: Biotechnic and Histochemistry - December 7, 2017 Category: Research Authors: Vélez C, Barbeito C, Koncurat M Tags: Biotech Histochem Source Type: research

Quantitative Proteomic and Phosphoproteomic Profiling of Ischemic Myocardial Stunning in Swine.
Abstract Despite decades of research on pathophysiology of myocardial stunning, protein changes and/or phosphorylation status underlying alterations in cardiac function/structure remain inadequately understood. Here, we utilized comprehensive and quantitative proteomic and phosphoproteomic approaches to explore molecular mechanisms of myocardial stunning in swine. The closed-chest swine (n=5) were subjected to a 10-minute LAD occlusion producing regional myocardial stunning. Tissues from the ischemic LAD region and a remote non-ischemic area of the left ventricle were collected 1-hour after reperfusion. Ion curren...
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 29, 2020 Category: Physiology Authors: Wang X, Shen X, Weil BR, Young RF, Canty JM, Qu J Tags: Am J Physiol Heart Circ Physiol Source Type: research

Protective Efficacy of an Orf Virus-Vector Encoding the Hemagglutinin and the Nucleoprotein of Influenza A Virus in Swine
This study demonstrates the potential of ORFV-based vector for control of swine influenza virus in swine.
Source: Frontiers in Immunology - November 5, 2021 Category: Allergy & Immunology Source Type: research

Magnetic-bead-based DNA-capture-assisted real-time polymerase chain reaction and recombinase polymerase amplification for the detection of African swine fever virus
In this study, ASFV DNA was efficiently captured from swine feces, serum, and tissue samples. Both DNA-capture-assisted qPCR and RPA-based detection methods have a limit of detection (LOD) of 102 copies/ µl, which is comparable to those of commercially available kits. In addition, an RPA-SYBR Green I method was developed for the immediate visual detection of ASFV DNA, which is time-saving and efficient for resource-limited field settings. In summary, a rapid, versatile, sequence-specific DNA captur e method was developed to efficiently capture ASFV DNA from swine clinical samples and subsequent detection by qPCR and RPA, ...
Source: Archives of Virology - January 3, 2023 Category: Virology Source Type: research

Viruses, Vol. 15, Pages 1438: Special Issue & ldquo;African Swine Fever and Other Swine Viral Diseases in Africa & rdquo;
Viruses, Vol. 15, Pages 1438: Special Issue “African Swine Fever and Other Swine Viral Diseases in Africa” Viruses doi: 10.3390/v15071438 Authors: Penrith Okoth Livio Heath African swine fever (ASF) has become the swine disease of most global concern since its second escape from Africa in 2007 resulted in its spread to five continents and the consequent devastation of industrial to subsistence pig farming [...]
Source: Viruses - June 26, 2023 Category: Virology Authors: Penrith Okoth Livio Heath Tags: Editorial Source Type: research

C-reactive protein, haptoglobin, serum amyloid A and pig major acute phase protein response in pigs simultaneously infected with H1N1 swine influenza virus and Pasteurella multocida
Conclusions: The results of current study confirmed that monitoring of APP may revealed ongoing infection, and in this way may be useful in selecting clinically healthy pigs (i.e. before integration into an uninfected herd). Present results corroborated our previous findings that SAA could be a potentially useful indicator in experimental infection studies (e.g. vaccine efficiency investigations) or as a marker for disease severity, because of correlation observed between its concentration in serum and disease severity (lung scores, clinical scores).
Source: BMC Veterinary Research - Latest articles - January 18, 2013 Category: Veterinary Research Authors: Malgorzata Pomorska-MólIwona Markowska-DanielKrzysztof KwitKatarzyna StepniewskaZygmunt Pejsak Source Type: research

The role of noncoding regions of classical swine fever virus C-strain in its adaptation to the rabbit.
Abstract Classical swine fever (CSF) is a devastating disease of swine caused by classical swine fever virus (CSFV). C-strain, a modified live vaccine against CSF, was developed through hundreds of passages of a highly virulent CSFV in the rabbit in China in the mid-1950s. To identify the role of noncoding regions (NCRs) of C-strain in its adaptation to the rabbit, we generated and evaluated a series of chimeric viruses derived from C-strain and the highly virulent Shimen strain. The results demonstrated that the NCRs of the C-strain were essential for its fever induction in rabbits and the coding region but not N...
Source: Virus Research - February 16, 2014 Category: Virology Authors: Li C, Li Y, Shen L, Huang J, Sun Y, Luo Y, Zhao B, Wang C, Yuan J, Qiu HJ Tags: Virus Res Source Type: research