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More Visible Examples of Progress in the Longevity Biotech Industry in 2022
Much of the progress that takes place year after year in any segment of the broader biotech industry is invisible, and the growing portion of that industry focused on aging and longevity is no exception. Biotech is not a high profile industry, particularly because of the heavy dependence on intellectual property and trade secrets as a basis for government-granted monopolies on particular treatments. Details are kept quiet least larger entities in the industry to decide replicate a therapy and call it their own, because the potential rewards are worth the near certainty of a lawsuit. Thus every visible presentation or press...
Source: Fight Aging! - February 22, 2023 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
Fight Aging! Newsletter, February 20th 2023
In this study, researchers stimulate the ghrelin receptor using a suitable small molecule for much of the lifespan of mice, and observe the results. The overall extension of life span is a quarter of that produced by calorie restriction, and so we might draw some conclusions from that as to the relative importance of hunger in the benefits resulting from the practice of calorie restriction or fasting. Interestingly, the short term weight gains observed in mice given this ghrelin receptor agonist in the past don't appear in this long term study, in which the controls are the heaver animals. This is possibly because the rese...
Source: Fight Aging! - February 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Retrieving Billions in Overpayments by CMS
This article focuses on the relatively young technologies that enable CMS to uncover overbillings, whether they be errors or fraud. The article is based on an interview with Kel Pults, chief clinical officer and vice president of MediQuant. A future article will explain how Medicare Advantage plans are trying to improving data collection and reporting, and how AI helps.
Challenges of Investigating Overpayments
Undeserved payments are needles lurking in the haystack of 135 million Americans enrolled in Medicare, Medicaid, and the Children’s Health Insurance Program (CHIP). But the needles pile up fast. Improper payments f...
Source: EMR and HIPAA - February 17, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Analytics/Big Data Health IT Company Healthcare IT Regulations Revenue Cycle Management #COVID19 CMS COVID Reimbursement Healthcare AI Healthcare Analytics Kel Pults MAOs Medicare Advantage MediQuant Overp Source Type: blogs
All Three Legs of the Obamacare Stool Are Working Well – Part 2
BY GEORGE HALVORSON
2022 Medicare Advantage data gathering process change made last year just made upcoding for plans irrelevant and impossible, but the critics do not accept that it happened.
CMS just ended that upcoding debate for 2022 by completely killing the coding system for the plans, effective immediately. The plans can’t code risk levels up because the coding system was eliminated entirely for 2022.
RAPS is dead.
The payment approach for Medicare Advantage now has no upcoding components and the government just used their new and more accurate numbers to create the 2023 payment level for the pla...
Source: The Health Care Blog - February 17, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Affordable Care Act Medicaid Medicare Medicare Advantage Obamacare Source Type: blogs
How Omnichannel Messaging Can Solve Headaches for Healthcare Communications
The following is a guest article by Sandro Stupar, Product Management Director at Mitto.
Navigating the healthcare system in America can be byzantine and time-consuming. Despite the many advances in telehealth, mobile apps and walk-in health clinics, patients and caregivers frequently find themselves waiting (often impatiently) in long phone queues to make an appointment, renew a prescription or obtain lab results. There should be a better way.
There is. Increasingly, medical providers are borrowing from the classical marketing playbook and weaving omnichannel messaging into their communications. And, just as it has in o...
Source: EMR and HIPAA - February 14, 2023 Category: Information Technology Authors: Guest Author Tags: Administration Ambulatory Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Automation Group Communication HealthGrades Improve Patient Outcomes Mitto N Source Type: blogs
Tivity Health Acquires Industry Leading Digital Health and Wellness Platform Burnalong
Acquisition will accelerate digital transformation and enhance efforts to support diverse populations and address chronic disease
Tivity Health®, a leading provider of healthy life-changing solutions, today announced that it has acquired Burnalong®, a digital health, wellness and fitness platform. The acquisition will accelerate Tivity Health’s efforts to provide consumers with a robust digital platform and extensive health and wellness content, in addition to in-person opportunities through its network of fitness locations. Burnalong will also further enable Tivity Health to support diverse and at-risk populations...
Source: EMR and HIPAA - February 14, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Burnalong Chronic Disease Management Chronic Diseases Chronic Illness Daniel Freedman Digital Health Fitness and Wellness Health IT Acquisitions Healthcare M&A Mike Kott Richard Ashworth SilverSnea Source Type: blogs
Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed.
The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Microglial Autophagy in the Context of Neurodegenerative Conditions
Changes in the function and activity of microglia in the brain, innate immune cells analogous to the macrophages present in the rest of the body, are known to be involved in the onset and progression of neurodegenerative conditions. Aging and neurodegeneration are associated with a growing presence of both senescent microglia and activated microglia Both of these states producing inflammatory signaling, contributing to the chronic, unresolved inflammation of brain tissue that is also characteristic of later life.
Autophagy is the name given to a collection of cellular maintenance processes responsible for recycling ...
Source: Fight Aging! - February 10, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Epigenetics of Calorie Restriction
The practice of calorie restriction slows aging, albeit to a much greater degree in short-lived mammals than is the case in our own species. Evidence suggests that upregulation of the cellular maintenance processes of autophagy are the primary mechanism by which calorie restriction produces its benefits to health and life span. Calorie restriction produces a major reshaping of all aspects of cellular behavior, however, a wide range of epigenetic changes that, along with autophagy, are the subject of the discussion in this open access paper.
Autophagy, such as a double-edged sword, can maintain cell survival and de...
Source: Fight Aging! - February 9, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Reviewing the Development of Senotherapeutics
Today's open access paper is a very readable tour of the present state of research and development of therapies targeting senescent cells, whether to destroy them or alter their function in favorable ways. In both cases the primary goal is to reduce the senescence-associated secretory phenotype (SASP), the pro-growth, pro-inflammatory signaling that contributes to degenerative aging as the number of senescent cells rises over the course of later life. It is hoped that clearance of senescent cells will produce a sizable positive impact for late life health, reducing chronic inflammation, slowing the onset of near all age-re...
Source: Fight Aging! - February 7, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Aging as a Disease: a Zoo Contains Animals, But is Not Itself an Animal
The author of today's open access commentary is quite prolifically opinionated on the topic of mTOR and its status as a central pillar of programmed aging, particularly the hyperfunction version of programmed aging theories. Nonetheless, he sometimes has interesting things to say, as is the case here on the topic of whether aging is a disease. A great deal of ink has been spilled of late on the question of whether or not aging is a disease. This is the case not because everyone suddenly developed an interest in semantics, but rather because it directly affects the regulation of medical development, and thus the flow of fun...
Source: Fight Aging! - February 6, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, February 6th 2023
In conclusion, our study reveals that aging enhances atherosclerosis via increased inflammation of visceral fat. Our study suggests that future therapies targeting the visceral fat may reduce atherosclerosis diseaseburden in the expanding older population.
Is the Gut a Significant Source of Amyloid-β in Alzheimer's Disease?
https://www.fightaging.org/archives/2023/02/is-the-gut-a-significant-source-of-amyloid-%ce%b2-in-alzheimers-disease/
The early stages of Alzheimer's disease are characterized by rising levels of amyloid-β in the brain and the formation of misfolded amyloid aggregates. It is presentl...
Source: Fight Aging! - February 5, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Practicing Medicine without a License: When Patients and Politicians Play Doctor
BY MICHAEL KIRSCH
We’ve all heard the adage, leave it to the professionals. It’s typically used when an individual has wandered out of his lane. How many folks go beyond their knowledge and skills with home projects, for example, who must then hire a real professional to mop up the mistakes? Luckily for me, the only tools that I – a gastroenterologist – know how to use are a colonoscope and an endoscope, so there’s no chance that I will be tempted to perform any plumbing or electrical tasks at home.
Although patients are not medical professionals, they routinely bring me results...
Source: The Health Care Blog - February 1, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Medical Marijuana Medical Practice medical professionals michael kirsch politicians Source Type: blogs
Fight Aging! Newsletter, January 30th 2023
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes.
Communication Between Blood and Brain in Aging and Rejuvenation
https://www.fightaging.org/archives/2023/01/communication-between-blood-and-brain-in-aging-and-rejuvenation/
As noted here, joining the circulatory systems of an old and young mouse results in some degree of rejuvenation in the old mouse. Where brain function is improved, researchers are inter...
Source: Fight Aging! - January 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Using Design Thinking to Advance SDOH Data Exchange Initiatives
The following is a guest article by Sarah Samis, VP, Public Health Products & Platforms at GCOM.
Chronic diseases, which most Americans have at least one of, are the leading causes of death and disability in the U.S. These ongoing and usually incurable diseases account for more than 80% of hospital admissions, 90% of prescriptions filled, and 75% of all physician’s visits. Two-thirds of all deaths are caused by five chronic diseases in particular: heart disease, cancer, stroke, diabetes, and chronic obstructive pulmonary disease.
Preventing and managing chronic disease is not solely a job for an individual and thei...
Source: EMR and HIPAA - January 26, 2023 Category: Information Technology Authors: Guest Author Tags: Analytics/Big Data Communication and Patient Experience Healthcare IT cancer CDC Center for Disease Control Chronic Diseases Chronic Illness Chronic Obstructive Pulmonary Disease Data Exchange Design Thinking diabetes GCOM Heart Source Type: blogs
