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Calorie Restriction as a Treatment to Slow Parkinson ' s Disease
Calorie restriction is known to suppress inflammation to some degree, alongside many other benefits to health that result from the reaction of cells and biological systems to a reduced calorie intake. Since chronic inflammation in brain tissue is implicated in the onset and development of neurodegenerative conditions, this makes calorie restriction a topic of interest in this part of the field. With a few exceptions, that interest largely manifests as research aimed at reproducing some of the metabolic alterations of calorie restriction with small molecule drugs, however, rather than more more rigorously testing calorie re...
Source: Fight Aging! - December 2, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Top 10 Digital Health Stories Of 2022
Edging towards the end of the year, it is time for a summary of how digital health progressed in 2022. It is easy to get lost in the noise – I myself shared well over a thousand articles, studies and news items between January and the end of November 2022. Thus, just like in 2021, 2020 (and so on), I picked the 10 topics I believe will have the most significance in the future of healthcare. 1. The Rise Of Digital Therapeutics (DTx) Unlike a number of unsubstantial hypes (NFTs, Metaverse to name a few), we see DTx as a meaningful trend that has the capacity to bring major short-term improvements in personalised ...
Source: The Medical Futurist - November 29, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF digital health pharma drones digital health trends vocal biomarkers WHO DTx digital therapeutics Metaverse virtual ward summary AI healthcare worker Source Type: blogs

Fight Aging! Newsletter, November 28th 2022
This study explored whether determining the gain or loss of specific taxa represent a more precise metric of healthy/unhealthy aging than summary microbiome statistics, such as diversity and uniqueness. We analyzed microbiome diversity and four measures of microbiome uniqueness in 21,000 gut microbiomes for their relationship with aging and health. We show that diversity and uniqueness measures are not synonymous; uniqueness is not a uniformly desirable feature of the aging microbiome, nor is it an accurate biomarker of healthy aging. Different measures of uniqueness show different associations with diversity and with mark...
Source: Fight Aging! - November 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Further Discussion of the Poor Evidence For Metformin to Even Mildly Slow Aging`
The problem with metformin as a drug to slow aging is that the evidece to support that use is very poor. In animal studies, the results are very unreliable, and the Interventions Testing Program found no effect in its highly overengineered studies. Further, the existing human data is not supportive, taken as a whole. Even if we did want to cherry pick the better data and be hopeful, the effect size compares unfavorably with that achieved through regular exercise, and further appears to be only achieved in people with the abnormal metabolism associated with obesity and diabetes. All of the work that was done to convince the...
Source: Fight Aging! - November 24, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Grip Strength Remains a Decent Biomarker of Aging
Of the various simple measures that correlate with mortality and risk of age-related disease, grip strength remains a relatively good option, even in this modern era of epigenetic clocks. Illustrative of this point, researchers here show a correlation between grip strength and epigenetic age data in a sizable study population. The degree to which an individual suffers from the chronic inflammation of aging may be an important determinant of this relationship. Inflammation disrupts tissue function throughout the body, and maintenance of muscle mass and strength is one of the aspects of health negatively affected by unresolv...
Source: Fight Aging! - November 21, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, November 21st 2022
In this study researchers added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been 'be active, be healthy', now researchers can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer. The study combined an animal model in which mice were trained under a strict exercise regimen, with data from healthy human volunteers examined before and after running. The human data, obtained from an epidemiological study ...
Source: Fight Aging! - November 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

High Intensity Aerobic Activity Correlates with a Sizable Reduction in Metastatic Cancer Risk
In this study researchers added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been 'be active, be healthy', now researchers can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer. The study combined an animal model in which mice were trained under a strict exercise regimen, with data from healthy human volunteers examined before and after running. The human data, obtained from an epidemiological study ...
Source: Fight Aging! - November 18, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Bonus Features, HLTH Edition – November 15, 2022 – News from Amwell, Epic, Google, MEDITECH, Microsoft, and more, plus the dates for HLTH Europe
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. This edition is a special dispatch from HLTH 2022. There have been a lot of new research reports, new products, and news partnerships announced at the event. We wanted to try and cover as many announcements for the Healthcare IT...
Source: EMR and HIPAA - November 15, 2022 Category: Information Technology Authors: Brian Eastwood Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Accolade AMA Amwell ApoWiser Bamboo Health Bayer BioT Medical Capital Rx Carenostics Commure Consensus Cloud Solutions COTA e-Psychiatry Ellisis Source Type: blogs

Bonus Features – November 13, 2022 – HCA extends 30-year relationship with MEDITECH, cost of care replaces pandemic as top reason to defer care, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Research HCA Healthcare signed a new agreement for a large-scale deployment of MEDITECH Expanse, continuing a relationship with the EHR vendor that has spanned three decades and been recognized with the 2021 CHIME Colla...
Source: EMR and HIPAA - November 13, 2022 Category: Information Technology Authors: Brian Eastwood Tags: EMR-EHR Healthcare IT AbsoluteCare Atropos Health BARDA Bioverge Cerner CharmHealth directtrust HCA Healthcare HCTec Healthcare IT Today Bonus Features Hugh Chatham Memorial Hospital Julie McCorkle Lifehouse MDaudit Meditec Source Type: blogs

Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting. Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Cardiovascular disease in England: supporting leaders to take actions
This report aims to inform and support national and local leaders to take action to accelerate progress on tackling CVD.Read the report
Source: Health Management Specialist Library - November 11, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: Public health and health inequalities Source Type: blogs

High Blood Pressure and Erectile Dysfunction
Research confirms that high blood pressure and ED are closely linked. But did you know the majority of cases of ED are caused by hypertension? Keep reading to find out more. Experts suggest that “hypertension is sometimes a standalone condition and sometimes it’s associated with other conditions, which also impact erectile dysfunction.” According to the European Society of Cardiology, this likelihood is almost double in men with uncontrolled high blood pressure. Long-term exposure to hypertension and elevated blood pressure damages the arterial wall. This leads to atherosclerosis and the narrowing of art...
Source: The EMT Spot - November 8, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs

Advancing American Indian and Alaska Native Health Through Research, Training, and Engagement
American Indian and Alaska Native (AI/AN) populations have long experienced health disparities such as higher rates of diabetes, certain cancers, and mental health conditions than those of other Americans. One contributing factor in these disparities is underrepresentation of AI/AN populations in biomedical science—as study participants, researchers, and health professionals. Unfamiliarity with health care options and opportunities, coupled with a distrust of biomedical research resulting from unethical studies in the past, have exacerbated this underrepresentation. NIGMS-supported researchers, including Native scient...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 2, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Genes Injury and Illness COVID-19 Diseases Genomics Profiles Training Source Type: blogs

Fight Aging! Newsletter, October 31st 2022
This study used mice to evaluate how their lifestyles - eating fatty foods vs. healthy and exercising vs. not - affected the metabolites of their offspring. Metabolites are substances made or used when the body breaks down food, drugs or chemicals, or its own fat or muscle tissue. "We have previously shown that maternal and paternal exercise improve health of offspring. Tissue and serum metabolites play a fundamental role in the health of an organism, but how parental exercise affects offspring tissue and serum metabolites has not yet been investigated." Researchers used targeted metabolomics - the study of metaboli...
Source: Fight Aging! - October 30, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Weekly Overseas Health IT Links – 29th October, 2022.
This report presents CDC findings on telehealth use trends in 2021. It includes data from the National Health Interview Survey, a nationally representative household survey conducted throughout the year by the National Center for Health Statistics. -----https://www.usnews.com/news/health-news/articles/2022-10-13/women-older-adults-more-likely-to-use-telemedicine-in-2021Who Used Telemedicine in 2021?New data shows which groups have been most likely to use a health care option popular during the pandemic.By Christopher WolfOct. 13, 2022, at 12:01 a.m.More than 1 in 3 adults used telemedicine in the past year in 2021, ac...
Source: Australian Health Information Technology - October 29, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs