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Total 418 results found since Jan 2013.
Uber Launches Uber Health; Responding to Needs of Clinical Trial Subjects
A recent article aboutUber Health addressed a number of the features that will be available with this transportation service. I found the details interesting in terms of what Uber perceives as an important niche in the healthcare sector (see:Uber Launches Uber Health, Looks To Improve Patient Experience In Clinical Research) Below is an excerpt from the article:...Uber, is looking to expand their outreach to the clinical research community with the launch of Uber Health, a new dashboard the company hopes will remove transportation as a barrier to proper care.Using Uber Health, doctors and hospitals will be able to ar...
Source: Lab Soft News - April 24, 2018 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Healthcare Delivery Healthcare Information Technology Healthcare Innovations Medical Consumerism Source Type: blogs
Optogenetics Sparks New Research Tools
Imagine if scientists could zap a single cell (or group of cells) with a pulse of light that makes the cell move, or even turns on or off the cell’s vital functions.
Scientists are working toward this goal using a technology called optogenetics. This tool draws on the power of light-sensitive molecules, called opsins and cryptochromes, which are naturally occurring molecules found in the cell membranes of a wide variety of species, from microscopic bacteria and algae to plants and humans. These light-reacting molecules change their shape or activity when they sense light, so they can be used to trigger cellular activity,...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 24, 2018 Category: Research Authors: Barbara Vann Tags: Cell Biology Cells Cellular Processes Cool Tools/Techniques Proteins Source Type: blogs
Remote-Controlled Signal Activates T Cells for Cancer Immunotherapy
Researchers at Georgia Tech have developed a technique to remotely activate genetically-modified T cells to attack cancer. The method employs a near-infrared laser that heats gold nanorods present in the tumor, causing local heating. This heat activa...
Source: Medgadget - April 23, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Nanomedicine Oncology Source Type: blogs
Fight Aging! Newsletter, April 16th 2018
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
Source: Fight Aging! - April 15, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Three Recent Papers on the Use of Senolytic Therapies to Address Age-Related Disease
We present concepts of the immune response to tissue trauma as well as the interactions with SnCs and the local tissue environment. Finally, we discuss therapeutic implications of targeting SnCs in treating osteoarthritis.
Source: Fight Aging! - April 11, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Doctors Discuss Future of Medicine on eMedicoz: India's First Medical Education Centric Mobile app
Note by Dr Sumer Sethi Recently we launched our unique medical education centric app for young Doctors calledeMedicoz. On this in addition to routine discussions Doctors also discuss various aspects of the profession. In a recent discussion series young Doctors brainstormed and tried crystal balling the future of the medicine and technology. It is wonderful to hear their thoughts on future. It is for certain future looks really happening for medical profession, computers and machine learning will re- invent the way we practice medicine. Targeted therapy is another important area, 3D printing , understanding the value ...
Source: Sumer's Radiology Site - April 2, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Fight Aging! Newsletter, March 26th 2018
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - March 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, March 19th 2018
In this study, we did not observe significant age-dependent upregulation of the prominent SASP cytokine Il6 in any tissue, although an upward trend was observed that was consistent in magnitude with previous observations in the heart and kidney. This modest age-related upward trend could be explained by a previous report which demonstrated that senescent cell-secreted IL-6 acts in an autocrine manner, reinforcing the senescent state, rather than inducing senescence or promoting dysfunction in neighboring cells.
The decreased expression of Il6 with age we observed in the hypothalamus could be indicative of a lack or ...
Source: Fight Aging! - March 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Undoing Aging: An Interview with Aubrey de Grey
The Undoing Aging conference in Berlin is presently underway, a gathering of everyone who is anyone in the rejuvenation research community. It is hosted jointly by the SENS Research Foundation and the Forever Healthy Foundation, and is a unification of the varied themes of the past fifteen years of SENS conferences: the science of aging and its treatment from the earlier SENS conference series mixed with the industry, startup, and commercial development focus of the Rejuvenation Biotechnology series of recent years.
The first rejuvenation therapies to be implemented and shown to work, those based on clearance of sen...
Source: Fight Aging! - March 16, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Tetramethylpyrazine is Senolytic in Bone Marrow: Reduces Inflammation and Improves Stem Cell Function in Mice
In this study, we aimed to investigate the local effect of TMP on the bone marrow of aging mice and to determine whether the senescent phenotype of MSCs could be eliminated. Our findings revealed that local delivery of TMP eliminates the senescent phenotype of LepR+ MSCs via epigenetically modulating
Source: Fight Aging! - March 3, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Paligenosis as a Potential Source of Methods to Target Many Types of Cancer with One Type of Therapy
The future of the treatment of cancer will be, must be, dominated by classes of therapy that can be easily and cost-effective applied to many different types of cancer. Such therapies can only exist as a result of targeting mechanisms that are shared by many or all types of cancer. It must also be challenging or impossible for cancerous cells to do without these mechanisms. The biggest issue in cancer research over the past few decades, in my opinion, is the specificity of therapies, the amount of time and resources poured into efforts to produce treatments that can only work on one type or a few types of cancer, and that ...
Source: Fight Aging! - February 27, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Cancer Not As Scary?
How scary is a breast cancer, or any other type of cancer diagnosis these days? Thisarticle, Thanks to advances, diagnosis of breast cancer isn ’t as frightening as it was, claims it ' s not as scary as it used to be due to advances in diagnosis and treatment. However I beg to disagree. That is not the only reason. And societally, we have not changed enough.Do you remember in the 1970s and earlier when people didn ' t talk about cancer? No, they whispered about it. So-and-so has cancer.... when ' s the funeral? Nice sequence there. But that is how life was. No one talked about cancer because it was a death sent...
Source: Caroline's Breast Cancer Blog - February 25, 2018 Category: Cancer & Oncology Tags: breast cancer breast cancer treatment cancer diagnosis Source Type: blogs
Fight Aging! Newsletter, February 26th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - February 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Injectable Hydrogel Responds to Tumors to Release Chemo and Immunotherapies
Scientists at the University of North Carolina and North Carolina State University have developed an injectable polymer hydrogel that breaks down in response to reactive oxygen species (ROS) produced by tumor cells. During its controlled degradation,...
Source: Medgadget - February 22, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Materials Oncology Source Type: blogs
An Energetic Exploration of the Biochemistry of Cellular Senescence is Underway
In 2011 a research group published the results from an animal study that demonstrated, in a way that couldn't be ignored, that the accumulation of senescent cells is a significant cause of aging and age-related disease. In fact, the evidence for this to be the case had been compelling for a very long time - this demonstration came nearly a decade after Aubrey de Grey, on the basis of the existing evidence at the time, included cellular senescence as one of the causes of aging in the first published version of his SENS research proposals. Yet nothing had been done to move ahead and achieve something with this knowledge. Tha...
Source: Fight Aging! - February 20, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
