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Biochemical, Serological and Immunological Tests for Diagnosis of Coronavirus Disease 2019 (COVID-19) Patients: A Comprehensive Systematic Review and Meta-analysis
CONCLUSION: The results show lymphopenia, elevated ESR level, elevated CRP level, elevated serum amyloid-A, elevated TNFα, elevated procalcitonin level, elevated interleukin-6 level, reduced CD3, reduced CD4, elevated BNP, elevated LDH, reduced albumin, reduced pre-albumin, and elevated Ddimer levels as the most common findings at the time of admission.PMID:37646320 | DOI:10.2174/1871526523666230228144910
Source: Infectious Disorders Drug Targets - August 30, 2023 Category: Infectious Diseases Authors: Milad Azami Amirreza Jamshidbeigi Hadi Esmaeili Gouvarchin Ghaleh Reza Ranjbar Source Type: research
Utility of growth differentiation factor-15 as a predictor of cardiovascular surgery outcomes: Current research and future directions
This study acknowledges that the relationship between patient outcomes and elevated GDF-15 levels is not limited to CVDs or cardiac surgery but can be associated with variable diseases, including diabetes and cancer. Moreover, the normal range of GDF-15 is not well defined. Given its promise for improving patient care and outcomes in cardiovascular surgery, future research should explore the potential of GDF-15 as a biomarker for postoperative outcomes and target therapeutic intervention.PMID:37648079 | DOI:10.1016/j.jjcc.2023.08.013
Source: Journal of Cardiology - August 30, 2023 Category: Cardiology Authors: Ikuko Shibasaki Naoyuki Otani Motoshi Ouchi Taira Fukuda Taiki Matsuoka Shotaro Hirota Shohei Yokoyama Yuta Kanazawa Takashi Kato Riha Shimizu Masahiro Tezuka Yusuke Takei Go Tsuchiya Shunsuke Saito Taisuke Konishi Koji Ogata Shigeru Toyoda Hirotsugu Fuku Source Type: research
Biochemical, Serological and Immunological Tests for Diagnosis of Coronavirus Disease 2019 (COVID-19) Patients: A Comprehensive Systematic Review and Meta-analysis
CONCLUSION: The results show lymphopenia, elevated ESR level, elevated CRP level, elevated serum amyloid-A, elevated TNFα, elevated procalcitonin level, elevated interleukin-6 level, reduced CD3, reduced CD4, elevated BNP, elevated LDH, reduced albumin, reduced pre-albumin, and elevated Ddimer levels as the most common findings at the time of admission.PMID:37646320 | DOI:10.2174/1871526523666230228144910
Source: Infectious Disorders Drug Targets - August 30, 2023 Category: Infectious Diseases Authors: Milad Azami Amirreza Jamshidbeigi Hadi Esmaeili Gouvarchin Ghaleh Reza Ranjbar Source Type: research
Utility of growth differentiation factor-15 as a predictor of cardiovascular surgery outcomes: Current research and future directions
This study acknowledges that the relationship between patient outcomes and elevated GDF-15 levels is not limited to CVDs or cardiac surgery but can be associated with variable diseases, including diabetes and cancer. Moreover, the normal range of GDF-15 is not well defined. Given its promise for improving patient care and outcomes in cardiovascular surgery, future research should explore the potential of GDF-15 as a biomarker for postoperative outcomes and target therapeutic intervention.PMID:37648079 | DOI:10.1016/j.jjcc.2023.08.013
Source: Journal of Cardiology - August 30, 2023 Category: Cardiology Authors: Ikuko Shibasaki Naoyuki Otani Motoshi Ouchi Taira Fukuda Taiki Matsuoka Shotaro Hirota Shohei Yokoyama Yuta Kanazawa Takashi Kato Riha Shimizu Masahiro Tezuka Yusuke Takei Go Tsuchiya Shunsuke Saito Taisuke Konishi Koji Ogata Shigeru Toyoda Hirotsugu Fuku Source Type: research
Biochemical, Serological and Immunological Tests for Diagnosis of Coronavirus Disease 2019 (COVID-19) Patients: A Comprehensive Systematic Review and Meta-analysis
CONCLUSION: The results show lymphopenia, elevated ESR level, elevated CRP level, elevated serum amyloid-A, elevated TNFα, elevated procalcitonin level, elevated interleukin-6 level, reduced CD3, reduced CD4, elevated BNP, elevated LDH, reduced albumin, reduced pre-albumin, and elevated Ddimer levels as the most common findings at the time of admission.PMID:37646320 | DOI:10.2174/1871526523666230228144910
Source: Infectious Disorders Drug Targets - August 30, 2023 Category: Infectious Diseases Authors: Milad Azami Amirreza Jamshidbeigi Hadi Esmaeili Gouvarchin Ghaleh Reza Ranjbar Source Type: research
Utility of growth differentiation factor-15 as a predictor of cardiovascular surgery outcomes: Current research and future directions
This study acknowledges that the relationship between patient outcomes and elevated GDF-15 levels is not limited to CVDs or cardiac surgery but can be associated with variable diseases, including diabetes and cancer. Moreover, the normal range of GDF-15 is not well defined. Given its promise for improving patient care and outcomes in cardiovascular surgery, future research should explore the potential of GDF-15 as a biomarker for postoperative outcomes and target therapeutic intervention.PMID:37648079 | DOI:10.1016/j.jjcc.2023.08.013
Source: Journal of Cardiology - August 30, 2023 Category: Cardiology Authors: Ikuko Shibasaki Naoyuki Otani Motoshi Ouchi Taira Fukuda Taiki Matsuoka Shotaro Hirota Shohei Yokoyama Yuta Kanazawa Takashi Kato Riha Shimizu Masahiro Tezuka Yusuke Takei Go Tsuchiya Shunsuke Saito Taisuke Konishi Koji Ogata Shigeru Toyoda Hirotsugu Fuku Source Type: research
Biochemical, Serological and Immunological Tests for Diagnosis of Coronavirus Disease 2019 (COVID-19) Patients: A Comprehensive Systematic Review and Meta-analysis
CONCLUSION: The results show lymphopenia, elevated ESR level, elevated CRP level, elevated serum amyloid-A, elevated TNFα, elevated procalcitonin level, elevated interleukin-6 level, reduced CD3, reduced CD4, elevated BNP, elevated LDH, reduced albumin, reduced pre-albumin, and elevated Ddimer levels as the most common findings at the time of admission.PMID:37646320 | DOI:10.2174/1871526523666230228144910
Source: Infectious Disorders Drug Targets - August 30, 2023 Category: Infectious Diseases Authors: Milad Azami Amirreza Jamshidbeigi Hadi Esmaeili Gouvarchin Ghaleh Reza Ranjbar Source Type: research
A blood-based marker of mitochondrial DNA damage in Parkinson's disease
Sci Transl Med. 2023 Aug 30;15(711):eabo1557. doi: 10.1126/scitranslmed.abo1557. Epub 2023 Aug 30.ABSTRACTParkinson's disease (PD) is the most common neurodegenerative movement disorder, and neuroprotective or disease-modifying interventions remain elusive. High-throughput markers aimed at stratifying patients on the basis of shared etiology are required to ensure the success of disease-modifying therapies in clinical trials. Mitochondrial dysfunction plays a prominent role in the pathogenesis of PD. Previously, we found brain region-specific accumulation of mitochondrial DNA (mtDNA) damage in PD neuronal culture and anima...
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Rui Qi Esther Sammler Claudia P Gonzalez-Hunt Ivana Barraza Nicholas Pena Jeremy P Rouanet Yahaira Naaldijk Steven Goodson Marie Fuzzati Fabio Blandini Kirk I Erickson Andrea M Weinstein Michael W Lutz John B Kwok Glenda M Halliday Nicolas Dzamko Shalini Source Type: research
Beta-cell death and dysfunction drives hyperglycaemia in organ donors
CONCLUSIONS: In pancreas donors, hyperglycaemia requiring IT is strongly associated with beta-cell death. This provides an explanation for the relationship of donor IT with post-transplant beta-cell dysfunction in transplant recipients.PMID:37646197 | DOI:10.1111/dom.15248
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Iestyn M Shapey Angela Summers James O'Sullivan Catherine Fullwood Neil A Hanley John Casey Shareen Forbes Miranda Rosenthal Paul R V Johnson Pratik Choudhary James Bushnell James A M Shaw Daniel Neiman Ruth Shemer Benjamin Glaser Yuval Dor Titus Augustin Source Type: research
Biochemical, Serological and Immunological Tests for Diagnosis of Coronavirus Disease 2019 (COVID-19) Patients: A Comprehensive Systematic Review and Meta-analysis
CONCLUSION: The results show lymphopenia, elevated ESR level, elevated CRP level, elevated serum amyloid-A, elevated TNFα, elevated procalcitonin level, elevated interleukin-6 level, reduced CD3, reduced CD4, elevated BNP, elevated LDH, reduced albumin, reduced pre-albumin, and elevated Ddimer levels as the most common findings at the time of admission.PMID:37646320 | DOI:10.2174/1871526523666230228144910
Source: Infectious Disorders Drug Targets - August 30, 2023 Category: Infectious Diseases Authors: Milad Azami Amirreza Jamshidbeigi Hadi Esmaeili Gouvarchin Ghaleh Reza Ranjbar Source Type: research
Protein kinase C epsilon activation regulates proliferation, migration, and epithelial to mesenchymal-like transition in rat Schwann cells
DISCUSSION: PKCε mediates relevant actions in the neuronal and glial compartment of the PNS. In particular, we posit a novel function for PKCε in the transformation of SCs, assuming a role in the mechanisms controlling SCs' fate and plasticity.PMID:37645595 | PMC:PMC10461112 | DOI:10.3389/fncel.2023.1237479
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Tasnim Mohamed Alessandra Colciago Marina Montagnani Marelli Roberta Manuela Moretti Valerio Magnaghi Source Type: research
Utility of growth differentiation factor-15 as a predictor of cardiovascular surgery outcomes: Current research and future directions
This study acknowledges that the relationship between patient outcomes and elevated GDF-15 levels is not limited to CVDs or cardiac surgery but can be associated with variable diseases, including diabetes and cancer. Moreover, the normal range of GDF-15 is not well defined. Given its promise for improving patient care and outcomes in cardiovascular surgery, future research should explore the potential of GDF-15 as a biomarker for postoperative outcomes and target therapeutic intervention.PMID:37648079 | DOI:10.1016/j.jjcc.2023.08.013
Source: Journal of Cardiology - August 30, 2023 Category: Cardiology Authors: Ikuko Shibasaki Naoyuki Otani Motoshi Ouchi Taira Fukuda Taiki Matsuoka Shotaro Hirota Shohei Yokoyama Yuta Kanazawa Takashi Kato Riha Shimizu Masahiro Tezuka Yusuke Takei Go Tsuchiya Shunsuke Saito Taisuke Konishi Koji Ogata Shigeru Toyoda Hirotsugu Fuku Source Type: research
