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Condition: Depression
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Total 96277 results found since Jan 2013.
Role of Minocycline as an Adjunct Neuroinflammatory Modulator in Treatment-Resistant Depression: A Systematic Review of Randomized Controlled Trials
Conclusions: The results were inconsistent regarding the clinical and neuroprotective role of minocycline in TRD. More study is needed to clarify the pathophysiologic and clinical role of minocycline as an immunomodulator in TRD.Prim Care Companion CNS Disord 2023;25(5):22r03467.Author affiliations are listed at the end of this article.PMID:37713730 | DOI:10.4088/PCC.22r03467
Source: The Primary Care Companion for CNS Disorders - September 15, 2023 Category: Primary Care Authors: Wisam Al Jumaili Darshini Vora Chintan Trivedi Shailesh Jain Source Type: research
Psychosocial Well-Being and Quality of Life in Uveitis: A Review
CONCLUSION: Given the heterogeneity of instruments used, it is worth considering standardization across large uveitis studies and trials. Beyond research, given the biopsychosocial effects on patients with uveitis, there are benefits to incorporating QOL and psychosocial assessments into clinical practice. Simplification of questionnaires into abridged forms, focusing on the most clinically relevant aspects of patient care, may be considered.PMID:37713271 | DOI:10.1080/09273948.2023.2247077
Source: Ocular Immunology and Inflammation - September 15, 2023 Category: Allergy & Immunology Authors: Zheting Zhang Konstadina Griva William Rojas-Carabali Gazal Patnaik Renee Liu Lucia Sobrin John H Kempen Robert P Finger Vishali Gupta Bryan Ang Rupesh Agrawal Source Type: research
Effect of work from home and employee mental health through mediating role of workaholism and work-family balance
This study provides real-world guidance to human resource managers on how to prioritize composite-level interventions at all levels of the university to create highly satisfied employees, provide a good working environment, and improve employees' mental health.ORIGINALITY/VALUE: Many researches have been done on the relationship between work-from-home and employee mental health, but relatively few have looked at how work-life balance and workaholism play a role in how work-from-home affects employees' mental health. This study fills a need in the academic and practitioner literature by investigating the relationship betwee...
Source: The International Journal of Social Psychiatry - September 15, 2023 Category: Psychiatry Authors: Chitra Krishnan Shailender Singh Mubashir Majid Baba Source Type: research
Sodium channel endocytosis drives axon initial segment plasticity
Sci Adv. 2023 Sep 15;9(37):eadf3885. doi: 10.1126/sciadv.adf3885. Epub 2023 Sep 15.ABSTRACTActivity-dependent plasticity of the axon initial segment (AIS) endows neurons with the ability to adapt action potential output to changes in network activity. Action potential initiation at the AIS highly depends on the clustering of voltage-gated sodium channels, but the molecular mechanisms regulating their plasticity remain largely unknown. Here, we developed genetic tools to label endogenous sodium channels and their scaffolding protein, to reveal their nanoscale organization and longitudinally image AIS plasticity in hippocamp...
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Am élie Fréal Nora Jamann Jolijn Ten Bos Jacqueline Jansen Naomi Petersen Thijmen Ligthart Casper C Hoogenraad Maarten H P Kole Source Type: research
Emotion dynamics of clients with test anxiety before and after an imagery-based treatment
CONCLUSION: These results provide first evidence for the idea that emotion dynamics may be associated with response to treatment for TA. Furthermore, effective imagery-based treatments may be tied to changes within these dynamics.PMID:37714799 | DOI:10.1016/j.jbtep.2023.101909
Source: Behavior Therapy - September 15, 2023 Category: Psychiatry & Psychology Authors: Jessica Uhl Steffen Eberhardt Brian Schwartz Eshkol Rafaeli Wolfgang Lutz Source Type: research
Factors associated with depression among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis
Psychol Med. 2023 Sep 15:1-10. doi: 10.1017/S0033291723002271. Online ahead of print.ABSTRACTThe COVID-19 pandemic has had a profound impact on the mental health of healthcare workers (HCWs). We aimed to identify the factors associated with depression among HCWs during the pandemic. We conducted literature search using eight electronic databases up to July 27 2022. Observational studies with more than 200 participants investigating correlates of depression in HCWs after COVID-19 outbreak were included. We used fixed- and random-effects models to pool odds ratios (ORs) across studies, and Cochran's chi-squared test and I 2 ...
Source: Psychological Medicine - September 15, 2023 Category: Psychiatry Authors: Haoyu Tian Tianci Qiao Jing Teng Chen Kang Jia Ke Lili Shan Mengting Li Chun Shen Yan Han Source Type: research
Negative mood and optimism bias: An experimental investigation of sadness and belief updating
CONCLUSIONS: These findings suggest that momentary fluctuations in mood affect how individuals integrate information to form beliefs.PMID:37714798 | DOI:10.1016/j.jbtep.2023.101910
Source: Behavior Therapy - September 15, 2023 Category: Psychiatry & Psychology Authors: Aleksandr T Karnick Brian W Bauer Daniel W Capron Source Type: research
Cognitive Behaviour Therapy (CBT) for Depersonalization Derealization Disorder (DDD): a self-controlled cross-over study of waiting list vs. active treatment
We report on a clinical audit of 36 participants with a diagnosis of chronic DDD who were sequentially recruited from a specialist DDD National Health Service clinic in London, United Kingdom, and who completed Cognitive Behavioural Therapy specifically adapted for DDD. The sample population had a mean age of 38.7 years (s.d. = 13.4), 61% were male and 69% were of White ethnicity. Three outcomes were assessed (Cambridge Depersonalisation Scale [CDS], Beck Depression Inventory [BDI], and the Beck Anxiety Inventory [BAI]) at three time points in a naturalistic, self-controlled, cross-over design. Hierarchical longitudinal an...
Source: Behavior Therapy - September 15, 2023 Category: Psychiatry & Psychology Authors: Elaine C M Hunter Cheuk Lon Malcolm Wong Rafael Gafoor Glyn Lewis Anthony S David Source Type: research
The Combination of Depression and Obesity was Associated with Increased Incidence of Subsequent Total Knee Arthroplasty
CONCLUSION: The incidence of subsequent TKA was greatest for those with the combination of obesity and depression when compared to the Control group and those with individual diagnosis of obesity or depression.PMID:37714551 | DOI:10.3899/jrheum.2023-0367
Source: J Rheumatol - September 15, 2023 Category: Rheumatology Authors: Caitlin E W Conley David C Landy Christian Lattermann Joanne Borg-Stein Jamie E Collins Ana-Maria Vranceanu Cale A Jacobs Source Type: research
The SOFIA pilot study: assessing feasibility and fidelity of coordinated care to reduce excess mortality and increase quality of life in patients with severe mental illness in a general practice setting; a cluster-randomised pilot trial
CONCLUSION: Our findings suggest that delivering the coordinated care program in a fully powered trial in primary care is likely feasible. However, the recruitment methodology requires improvement to ensure sufficient recruitment and minimize selective inclusion.TRIAL REGISTRATION: The date of pilot trial protocol registration was 05/11/2020, and the registration number is NCT04618250.PMID:37715123 | DOI:10.1186/s12875-023-02141-2
Source: Primary Care - September 15, 2023 Category: Primary Care Authors: Katrine Tranberg Alexandra J ønsson Tina Due Volkert Siersma John Brandt Brodersen Kristine Bissenbakker Frederik Martiny Annette Davidsen Pia K ürstein Kjellberg Kevin Doherty Stewart W Mercer Maria Haahr Nielsen Susanne Reventlow Anne M øller Maarten Source Type: research
Mental Health Screening Differences in Non-English Speaking Patients: Results From a Retrospective Cohort Study
CONCLUSIONS: Results highlight the inequities between the language groups that are probably the result of the challenges to access multilingual depression and anxiety screening instruments. Furthermore, providers may be prone to bias about who they think "needs" a mental health screening. We suggest that measures are implemented to ensure consistency in mental health screening regardless of a patients' preferred language.PMID:37714820 | DOI:10.1177/21501319231200304
Source: Primary Care - September 15, 2023 Category: Primary Care Authors: Frank M üller Alyssa M Abdelnour Diana N Rutaremara Judith E Arnetz Eric D Achtyes Omayma Alshaarawy Harland T Holman Source Type: research
Role of Minocycline as an Adjunct Neuroinflammatory Modulator in Treatment-Resistant Depression: A Systematic Review of Randomized Controlled Trials
Conclusions: The results were inconsistent regarding the clinical and neuroprotective role of minocycline in TRD. More study is needed to clarify the pathophysiologic and clinical role of minocycline as an immunomodulator in TRD.Prim Care Companion CNS Disord 2023;25(5):22r03467.Author affiliations are listed at the end of this article.PMID:37713730 | DOI:10.4088/PCC.22r03467
Source: Primary Care - September 15, 2023 Category: Primary Care Authors: Wisam Al Jumaili Darshini Vora Chintan Trivedi Shailesh Jain Source Type: research
Insomnia Burden among Informal Caregivers of Hospitalized Lung Cancer Patients and Its Influencing Factors
CONCLUSION: Of the hospitalized patients with lung cancer, 51.9% experienced insomnia. Patients' ADL, ICs gender, alcohol consumption, underlying medical conditions, caregiving duration, and monthly expenses were influencing factors. Therefore, prompt screening and early intervention for ICs of patients with lung cancer is necessary.PMID:37711083 | DOI:10.3967/bes2023.099
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Chun Yan Li Yu Jian Song Lan Zhao Mu Hong Deng Rui Xin Li Xiao Ling Zhang Qiong Xuan Li Ying Shi Heng Yu Luan Yuan Yuan Sun Yi Hu Xiao Yong Sai Source Type: research
Evaluation of the Therapeutic Effect of Curcumin-Conjugated Zinc Oxide Nanoparticles on Reserpine-Induced Depression in Wistar Rats
In conclusion, curcumin-conjugated zinc oxide nanoparticles demonstrate potent antidepressant effects, alleviating depressive-like behavior in rats. These findings support Zn(cur)O NPs as a promising therapeutic strategy for depression management, warranting further investigation and clinical validation.PMID:37713054 | DOI:10.1007/s12011-023-03849-z
Source: Biological Trace Element Research - September 15, 2023 Category: Biology Authors: Heba M Fahmy Fatmaalzahraa A Aboalasaad Ayman S Mohamed Fathi A Elhusseiny Yasser A Khadrawy Ahmed Elmekawy Source Type: research
Psychobiotics for Mitigation of Neuro-Degenerative Diseases: Recent Advancements
Mol Nutr Food Res. 2023 Sep 15:e2300461. doi: 10.1002/mnfr.202300461. Online ahead of print.ABSTRACTAgeing is inevitable and poses a universal challenge for all living organisms, including humans. The human body experiences rapid cell division and metabolism until approximately 25 years of age, after which the accumulation of metabolic by-products and cellular damage leads to age-related diseases. Neurodegenerative diseases are of concern due to their irreversible nature, lack of effective treatment, and impact on society and the economy. Researchers are interested in finding drugs that can effectively alleviate ageing and...
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Priya Dhyani Chhaya Goyal Sanju Bala Dhull Anil Kumar Chauhan Baljeet Singh Saharan None Harshita Joginder Singh Duhan Gulden Goksen Source Type: research
