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Condition: Depression

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Total 96277 results found since Jan 2013.

The challenges of defining and managing treatment-resistant depression in research and practice
World Psychiatry. 2023 Oct;22(3):350-351. doi: 10.1002/wps.21128.NO ABSTRACTPMID:37713579 | PMC:PMC10503900 | DOI:10.1002/wps.21128
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Maurizio Fava Source Type: research

World Health Organization's low-intensity psychosocial interventions: a systematic review and meta-analysis of the effects of Problem Management Plus and Step-by-Step
World Psychiatry. 2023 Oct;22(3):449-462. doi: 10.1002/wps.21129.ABSTRACTMany societies have been recently exposed to humanitarian and health emergencies, which have resulted in a large number of people experiencing significant distress and being at risk to develop mental disorders such as depression, anxiety and post-traumatic stress disorder. The World Health Organization has released a series of scalable psychosocial interventions for people impaired by distress in communities exposed to adversities. Prominent among these is a low-intensity transdiagnostic psychosocial intervention, Problem Management Plus (PM+), and it...
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Sarah K Sch äfer Lea M Thomas Saskia Lindner Klaus Lieb Source Type: research

The ICD-11 opens the door for overdue improved identification of depression in men
World Psychiatry. 2023 Oct;22(3):480-481. doi: 10.1002/wps.21124.NO ABSTRACTPMID:37713575 | PMC:PMC10503896 | DOI:10.1002/wps.21124
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: S øren D Østergaard Zac Seidler Simon Rice Source Type: research

Sodium channel endocytosis drives axon initial segment plasticity
Sci Adv. 2023 Sep 15;9(37):eadf3885. doi: 10.1126/sciadv.adf3885. Epub 2023 Sep 15.ABSTRACTActivity-dependent plasticity of the axon initial segment (AIS) endows neurons with the ability to adapt action potential output to changes in network activity. Action potential initiation at the AIS highly depends on the clustering of voltage-gated sodium channels, but the molecular mechanisms regulating their plasticity remain largely unknown. Here, we developed genetic tools to label endogenous sodium channels and their scaffolding protein, to reveal their nanoscale organization and longitudinally image AIS plasticity in hippocamp...
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Am élie Fréal Nora Jamann Jolijn Ten Bos Jacqueline Jansen Naomi Petersen Thijmen Ligthart Casper C Hoogenraad Maarten H P Kole Source Type: research

Transdiagnostic risk of mental disorders in offspring of affected parents: a meta-analysis of family high-risk and registry studies
This study demonstrates at a global, meta-analytic level that offspring of affected parents have strongly elevated RR and lifetime risk of developing any mental disorder as well as the same mental disorder diagnosed in the parent. The transdiagnostic risks suggest that offspring of parents with a range of mental disorders should be considered as candidates for targeted primary prevention.PMID:37713573 | PMC:PMC10503921 | DOI:10.1002/wps.21147
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Rudolf Uher Barbara Pavlova Joaquim Radua Umberto Provenzani Sara Najafi Lydia Fortea Maria Ortu ño Anna Nazarova Nader Perroud Lena Palaniyappan Katharina Domschke Samuele Cortese Paul D Arnold Jehannine C Austin Michael M Vanyukov Myrna M Weissman Alla Source Type: research

Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management
World Psychiatry. 2023 Oct;22(3):366-387. doi: 10.1002/wps.21110.ABSTRACTPopulations with common physical diseases - such as cardiovascular diseases, cancer and neurodegenerative disorders - experience substantially higher rates of major depressive disorder (MDD) than the general population. On the other hand, people living with MDD have a greater risk for many physical diseases. This high level of comorbidity is associated with worse outcomes, reduced adherence to treatment, increased mortality, and greater health care utilization and costs. Comorbidity can also result in a range of clinical challenges, such as a more com...
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Michael Berk Ole K öhler-Forsberg Megan Turner Brenda W J H Penninx Anna Wrobel Joseph Firth Amy Loughman Nicola J Reavley John J McGrath Natalie C Momen Oleguer Plana-Ripoll Adrienne O'Neil Dan Siskind Lana J Williams Andre F Carvalho Lianne Schmaal Ada Source Type: research

The lived experience of depression: a bottom-up review co-written by experts by experience and academics
World Psychiatry. 2023 Oct;22(3):352-365. doi: 10.1002/wps.21111.ABSTRACTWe provide here the first bottom-up review of the lived experience of depression, co-written by experts by experience and academics. First-person accounts within and outside the medical field were screened and discussed in collaborative workshops involving numerous individuals with lived experience of depression, family members and carers, representing a global network of organizations. The material was enriched by phenomenologically informed perspectives and shared with all collaborators in a cloud-based system. The subjective world of depression was...
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Paolo Fusar-Poli Andr és Estradé Giovanni Stanghellini Cecilia Maria Esposito Ren é Rosfort Milena Mancini Peter Norman Julieann Cullen Miracle Adesina Gema Benavides Jimenez Caroline da Cunha Lewin Esenam A Drah Marc Julien Muskan Lamba Edwin M Mutura Source Type: research

From treatment resistance to sequential treatments of depression
World Psychiatry. 2023 Oct;22(3):418-419. doi: 10.1002/wps.21138.NO ABSTRACTPMID:37713563 | PMC:PMC10503904 | DOI:10.1002/wps.21138
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Pim Cuijpers Source Type: research

Attentional biases in anxiety and depression: current status and clinical considerations
World Psychiatry. 2023 Oct;22(3):473-474. doi: 10.1002/wps.21117.NO ABSTRACTPMID:37713562 | PMC:PMC10503924 | DOI:10.1002/wps.21117
Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Jan De Houwer Ernst H W Koster Source Type: research

Evaluation of the Therapeutic Effect of Curcumin-Conjugated Zinc Oxide Nanoparticles on Reserpine-Induced Depression in Wistar Rats
In conclusion, curcumin-conjugated zinc oxide nanoparticles demonstrate potent antidepressant effects, alleviating depressive-like behavior in rats. These findings support Zn(cur)O NPs as a promising therapeutic strategy for depression management, warranting further investigation and clinical validation.PMID:37713054 | DOI:10.1007/s12011-023-03849-z
Source: Biological Trace Element Research - September 15, 2023 Category: Biology Authors: Heba M Fahmy Fatmaalzahraa A Aboalasaad Ayman S Mohamed Fathi A Elhusseiny Yasser A Khadrawy Ahmed Elmekawy Source Type: research

Effect of work from home and employee mental health through mediating role of workaholism and work-family balance
This study provides real-world guidance to human resource managers on how to prioritize composite-level interventions at all levels of the university to create highly satisfied employees, provide a good working environment, and improve employees' mental health.ORIGINALITY/VALUE: Many researches have been done on the relationship between work-from-home and employee mental health, but relatively few have looked at how work-life balance and workaholism play a role in how work-from-home affects employees' mental health. This study fills a need in the academic and practitioner literature by investigating the relationship betwee...
Source: The International Journal of Social Psychiatry - September 15, 2023 Category: Psychiatry Authors: Chitra Krishnan Shailender Singh Mubashir Majid Baba Source Type: research

Insomnia Burden among Informal Caregivers of Hospitalized Lung Cancer Patients and Its Influencing Factors
CONCLUSION: Of the hospitalized patients with lung cancer, 51.9% experienced insomnia. Patients' ADL, ICs gender, alcohol consumption, underlying medical conditions, caregiving duration, and monthly expenses were influencing factors. Therefore, prompt screening and early intervention for ICs of patients with lung cancer is necessary.PMID:37711083 | DOI:10.3967/bes2023.099
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Chun Yan Li Yu Jian Song Lan Zhao Mu Hong Deng Rui Xin Li Xiao Ling Zhang Qiong Xuan Li Ying Shi Heng Yu Luan Yuan Yuan Sun Yi Hu Xiao Yong Sai Source Type: research

Cognitive Behaviour Therapy (CBT) for Depersonalization Derealization Disorder (DDD): a self-controlled cross-over study of waiting list vs. active treatment
We report on a clinical audit of 36 participants with a diagnosis of chronic DDD who were sequentially recruited from a specialist DDD National Health Service clinic in London, United Kingdom, and who completed Cognitive Behavioural Therapy specifically adapted for DDD. The sample population had a mean age of 38.7 years (s.d. = 13.4), 61% were male and 69% were of White ethnicity. Three outcomes were assessed (Cambridge Depersonalisation Scale [CDS], Beck Depression Inventory [BDI], and the Beck Anxiety Inventory [BAI]) at three time points in a naturalistic, self-controlled, cross-over design. Hierarchical longitudinal an...
Source: Behavior Therapy - September 15, 2023 Category: Psychiatry & Psychology Authors: Elaine C M Hunter Cheuk Lon Malcolm Wong Rafael Gafoor Glyn Lewis Anthony S David Source Type: research

Psychosocial Well-Being and Quality of Life in Uveitis: A Review
CONCLUSION: Given the heterogeneity of instruments used, it is worth considering standardization across large uveitis studies and trials. Beyond research, given the biopsychosocial effects on patients with uveitis, there are benefits to incorporating QOL and psychosocial assessments into clinical practice. Simplification of questionnaires into abridged forms, focusing on the most clinically relevant aspects of patient care, may be considered.PMID:37713271 | DOI:10.1080/09273948.2023.2247077
Source: Ocular Immunology and Inflammation - September 15, 2023 Category: Allergy & Immunology Authors: Zheting Zhang Konstadina Griva William Rojas-Carabali Gazal Patnaik Renee Liu Lucia Sobrin John H Kempen Robert P Finger Vishali Gupta Bryan Ang Rupesh Agrawal Source Type: research

Factors associated with depression among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis
Psychol Med. 2023 Sep 15:1-10. doi: 10.1017/S0033291723002271. Online ahead of print.ABSTRACTThe COVID-19 pandemic has had a profound impact on the mental health of healthcare workers (HCWs). We aimed to identify the factors associated with depression among HCWs during the pandemic. We conducted literature search using eight electronic databases up to July 27 2022. Observational studies with more than 200 participants investigating correlates of depression in HCWs after COVID-19 outbreak were included. We used fixed- and random-effects models to pool odds ratios (ORs) across studies, and Cochran's chi-squared test and I 2 ...
Source: Psychological Medicine - September 15, 2023 Category: Psychiatry Authors: Haoyu Tian Tianci Qiao Jing Teng Chen Kang Jia Ke Lili Shan Mengting Li Chun Shen Yan Han Source Type: research