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Total 52199 results found since Jan 2013.

Sensation seeking, drinking motives, and going out mediate the link between eveningness and alcohol use and problems in adolescence
Chronobiol Int. 2023 Sep 18:1-11. doi: 10.1080/07420528.2023.2256396. Online ahead of print.ABSTRACTThe present study was aimed at obtaining a more comprehensive understanding of the possible mediating factors in the morningness-eveningness → alcohol consumption relation. We explored the role of mediators such as sensation seeking, the frequency of going out in the evenings, and drinking motives. We tested the proposed mediation model via structural equation modeling based on cross-sectional research conducted among Hungarian adolescents and young adults (N = 1695, 42.5% male, Mage = 18.98, SDage = 1.89). The outcomes in...
Source: Chronobiology International - September 18, 2023 Category: Biology Authors: Adrien Rig ó Istv án Tóth-Király Anna Magi Andrea Eisinger Zsolt Demetrovics R óbert Urbán Source Type: research

Covalent Capture and Selection of DNA-Encoded Chemical Libraries via Photo-Activated Lysine-Selective Crosslinkers
Chem Asian J. 2023 Sep 18:e202300652. doi: 10.1002/asia.202300652. Online ahead of print.ABSTRACTCovalent crosslinking probes have arisen as efficient toolkits to capture and elucidate biomolecular interaction networks. Exploiting the potential of crosslinking in DNA-encoded chemical library (DEL) selection methods significantly boosted bioactive ligand discovery in complex physiological contexts. Herein, we incorporated o-nitrobenzyl alcohol (o-NBA) as a photo-activated lysine-selective crosslinker into divergent DEL formats and achieved covalent capture of ligand-target interactions featuring improved crosslinking effici...
Source: Chemistry, an Asian Journal - September 18, 2023 Category: Chemistry Authors: Haimei Wei Tianyang Zhang Yangfeng Li Gong Zhang Yizhou Li Source Type: research

Photo-thermal Cooperative Carbonylation of Ethanol with CO2 on Cu2O-SrTiCuO3-x
Angew Chem Int Ed Engl. 2023 Sep 18:e202312068. doi: 10.1002/anie.202312068. Online ahead of print.ABSTRACTCarbonylation of ethanol with CO2 as carbonyl source into value-added esters is of considerable significance and interest, while remains of great challenge due to the harsh conditions for activation of inert CO2 in that the harsh conditions result in undesired activation of α-C-H and even cleavage of C-C bond in ethanol to deteriorate the specific activation of O-H bond. Herein, we propose a photo-thermal cooperative strategy for carbonylation of ethanol with CO2, in which CO2 is activated to reactive CO via photo-ca...
Source: Angewandte Chemie - September 18, 2023 Category: Chemistry Authors: Jian Zhang Chuanbao Shang Zhe An Yanru Zhu Hongyan Song Zhigang Chai Xin Shu Lirong Zheng Jing He Source Type: research

Flavor perception and health benefits of tea
This article aimed to provide a more comprehensive understanding of tea flavor (including aroma and taste) and the character of tea in preventing and alleviating diseases. The recent advanced modern analytical techniques for revealing flavor components in tea, including enrichment, identification, quantitation, statistics, and sensory evaluation methodologies, were summarized in the following content. Besides, the role of tea in anti-cancer, preventing cardiovascular disease and metabolic syndrome, anti-aging and neuroprotection, and regulating gut microbiota was also listed in this article. Moreover, questions and outlook...
Source: Advances in Food and Nutrition Research - September 18, 2023 Category: Nutrition Authors: Jieyao Yu Kangyi Zhang Yijun Wang Xiaoting Zhai Xiaochun Wan Source Type: research

Green preparation of magnetic ferroferric oxide-polyvinyl alcohol-alginate coated UiO-67 nanospheres: Characterization, adsorption properties and adsorption mechanism of methylene blue
Int J Biol Macromol. 2023 Sep 16:126967. doi: 10.1016/j.ijbiomac.2023.126967. Online ahead of print.ABSTRACTIn this paper, a kind of magnetic ferric oxide/polyvinyl alcohol/calcium alginate/UiO-67 (Fe3O4/PVA/CA/UiO-67) nanospheres with homogeneous surface interconnecting structures was prepared by using macromolecular polymer polyvinyl alcohol and sodium alginate as carriers and zirconium organic skeleton as nanocrystals. The properties of magnetic nanospheres were studied by SEM, FT-IR, TGA, XRD, BET, VSM and Zeta potential. The impression of diverse temperatures, MB concentrations, interaction time, pH, and magnetic aero...
Source: International Journal of Biological Macromolecules - September 18, 2023 Category: Biochemistry Authors: Zhenyu Jing Yanhui Li Qiuju Du Xinxin Pi Yuqi Wang Shiyong Zhao Yonghui Jin Source Type: research

CRISPR/Cas9-mediated deletion of adipocyte genes associated with NAFLD alters adipocyte lipid handling and reduces steatosis in hepatocytes < em > in vitro < /em >
Am J Physiol Cell Physiol. 2023 Sep 18. doi: 10.1152/ajpcell.00291.2023. Online ahead of print.ABSTRACTObesity is a major risk factor for the development of non-alcoholic fatty liver disease (NAFLD) and the subcutaneous white adipose tissue (scWAT) is the primary lipid storage depot and regulates lipid fluxes to other organs. Our previous work identified genes up-regulated in scWAT of patients with NAFLD: SOCS3, DUSP1, and SIK1. Herein, we knocked down (KD) their expression in human adipose-derived mesenchymal stem cells (hADMSCs) using CRISPR/Cas9 technology and characterized their phenotype. We found that SOCS3, DUSP1, a...
Source: Am J Physiol Cell Ph... - September 18, 2023 Category: Cytology Authors: Marta Lopez-Yus Scott Frendo-Cumbo Raquel Del Moral-Bergos Maria Pilar Garcia-Sobreviela Vanesa Bernal-Monterde Mikael Ryd én Silvia Lorente-Cebrian Jose M Arbones-Mainar Source Type: research

The risk of road traffic crashes for occupational drivers: A responsibility study with comparison to the general population
CONCLUSION: On-duty drivers showed lower risk of responsibility for an accident than other drivers. However, on-duty drivers on temporary or work/study contracts, who are usually not subject to specific regulations, showed higher risk, and should be the subject of particular attention regarding occupational risk prevention.PMID:37718828 | DOI:10.3233/WOR-220578
Source: Work - September 18, 2023 Category: Occupational Health Authors: Nicolas Guibert Jean-Louis Martin Blandine Gadegbeku Emmanuel Lagarde Barbara Charbotel Source Type: research

"Less is better" is the best message when talking to patients about alcohol
CMAJ. 2023 Sep 18;195(36):E1232-E1233. doi: 10.1503/cmaj.231238.NO ABSTRACTPMID:37722747 | DOI:10.1503/cmaj.231238
Source: cmaj - September 18, 2023 Category: General Medicine Authors: Savita Rani Andreas Laupacis Source Type: research

Preparation of blast furnace dust particle electrodes and their application in synergistic electrochemical degradation of saline polyvinyl alcohol wastewater
Environ Pollut. 2023 Sep 16:122574. doi: 10.1016/j.envpol.2023.122574. Online ahead of print.ABSTRACTPolyvinyl alcohol (PVA) has been widely used as a water-soluble plastic in laundry and dish detergent pods, yet wastewater contaminated with PVA is too difficult to be treated due to its high salinity and foaming. Here, we fabricated blast furnace dust (BFD) particle electrodes, and developed a three-dimensional electrocatalytic system (3DEC) to treat saline PVA wastewater. The optimum preparation condition for BFD particle electrode was iron carbon ratio of 2:1 doping with TiO2. The optimal parameters of 3DECs for PVA wast...
Source: Environmental Pollution - September 18, 2023 Category: Environmental Health Authors: Yue Wang Xinxin Qi Yanting Qin Chenyun An Jie Wang Jianhua Guo Source Type: research

Disulfiram-Like Reaction With Ginaton: A Case Report and Literature Review
This article details such a case from China. Healthcare providers should be proactive in educating patients about the potential adverse reactions related to using Ginaton and the importance of avoiding alcohol consumption while using it. Patients should also be advised to disclose their alcohol-consumption habits and seek medical advice before initiating treatment with any medication or supplement during treatment with Ginaton.PMID:37722955 | DOI:10.1016/j.clinthera.2023.08.013
Source: Clinical Therapeutics - September 18, 2023 Category: Drugs & Pharmacology Authors: Xiangji Dang Rui Wang Yan Liu Source Type: research

"Less is better" is the best message when talking to patients about alcohol
CMAJ. 2023 Sep 18;195(36):E1232-E1233. doi: 10.1503/cmaj.231238.NO ABSTRACTPMID:37722747 | DOI:10.1503/cmaj.231238
Source: cmaj - September 18, 2023 Category: General Medicine Authors: Savita Rani Andreas Laupacis Source Type: research

Flavor perception and health benefits of tea
This article aimed to provide a more comprehensive understanding of tea flavor (including aroma and taste) and the character of tea in preventing and alleviating diseases. The recent advanced modern analytical techniques for revealing flavor components in tea, including enrichment, identification, quantitation, statistics, and sensory evaluation methodologies, were summarized in the following content. Besides, the role of tea in anti-cancer, preventing cardiovascular disease and metabolic syndrome, anti-aging and neuroprotection, and regulating gut microbiota was also listed in this article. Moreover, questions and outlook...
Source: Advances in Food and Nutrition Research - September 18, 2023 Category: Nutrition Authors: Jieyao Yu Kangyi Zhang Yijun Wang Xiaoting Zhai Xiaochun Wan Source Type: research