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Condition: Pregnancy
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Timed intercourse for couples trying to conceive
CONCLUSIONS: The new evidence presented in this review update shows that timed intercourse using urine ovulation tests probably improves live birth and pregnancy rates (clinical or positive urine pregnancy tests but not yet confirmed by ultrasound) in women under 40, trying to conceive for less than 12 months, compared to intercourse without ovulation prediction. However, there are insufficient data to determine the effects of urine ovulation tests on adverse events, clinical pregnancy, time to pregnancy, and quality of life. Similarly, due to limited data, we are uncertain of the effect of FABM on pregnancy outcomes, adve...
Source: Cochrane Database of Systematic Reviews - September 14, 2023 Category: General Medicine Authors: Tatjana Gibbons Jane Reavey Ektoras X Georgiou Christian M Becker Source Type: research
A 10-Year Observational Study on Twin Pregnancy: Role of Fetal Sex Pairing on Obstetric Outcome
Twin Res Hum Genet. 2023 Sep 14:1-7. doi: 10.1017/thg.2023.38. Online ahead of print.ABSTRACTFetal sex contributes to the determination of obstetric outcome, as pregnancies carrying male babies seem to have an increased risk of maternal-fetal complications. Most studies have been conducted on singleton pregnancies, whereas less evidence is available for twins. A 10-year retrospective observational study was conducted on a cohort of 1180 women with twin pregnancy delivered at a single tertiary hospital. Clinical data on maternal characteristics, and obstetric and neonatal outcomes were collected, and the analysis was perfor...
Source: Twin Research and Human Genetics - September 14, 2023 Category: Genetics & Stem Cells Authors: Silvia Vannuccini Sara Bolzonella Chiara Colucci Costanza Nicchi Noemi Strambi Mariarosaria Di Tommaso Source Type: research
Prenatal Diagnosis and Molecular Cytogenetic Analyses of a de novo Deletion on Chromosome 4p16.3p15.33
Altern Ther Health Med. 2023 Sep 15:AT8915. Online ahead of print.ABSTRACTWolf-Hirschhorn syndrome (WHS) (OMIM 194190) is a contiguous gene syndrome with an estimated prevalence of around 1 in 50,000 births. The syndrome is caused by the deletion of a critical region (Wolf-Hirschhorn Syndrome Critical region-WHSCR) on chromosome 4p16.3. Its core features are typical facial gestalt, growth retardation, intellectual disability, developmental delay, and seizures. Prenatal diagnosis of WHS helps clinicians and parents make informed decisions about pregnancy management. In this research, a 31-year-old woman (gravida 1, para 0) ...
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Huili Luo Ruijie Chang Fangfang Liu Xia Gao Source Type: research
Establishment and Validation of Risk Prediction Model for Postpartum Hemorrhage for Pregnant Women ≥35 Years of Age in Natural Delivery
CONCLUSIONS: The PPH risk-prediction model for vaginal delivery for pregnant women ≥35 years of age showed that a greater age, pregnancy-induced hypertension, a lower prelabor FIB, a longer third stage of labor, and a higher birth weight for the newborn were significantly related to the incidence of PPH and that its use could be clinically helpful.PMID:37708560
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Chunxue Yang Hongxia Wu Source Type: research
High Maternal Adiposity During Pregnancy Programs an Imbalance in the Lipidome and Predisposes to Diet-induced Hepatosteatosis in the Offspring
CONCLUSION: High maternal adiposity during pregnancy programs a susceptibility to diet-induced hepatosteatosis.PMID:37706282 | DOI:10.1042/BSR20231060
Source: Bioscience Reports - September 14, 2023 Category: Biomedical Science Authors: Taylor B Scheidl Jessica L Wager Larissa G Baker Amy L Brightwell Katrina M Melan Sebastian Larion Ousseynou Sarr T R Regnault Stefan J Urbanski Jennifer Thompson Source Type: research
A 10-Year Observational Study on Twin Pregnancy: Role of Fetal Sex Pairing on Obstetric Outcome
Twin Res Hum Genet. 2023 Sep 14:1-7. doi: 10.1017/thg.2023.38. Online ahead of print.ABSTRACTFetal sex contributes to the determination of obstetric outcome, as pregnancies carrying male babies seem to have an increased risk of maternal-fetal complications. Most studies have been conducted on singleton pregnancies, whereas less evidence is available for twins. A 10-year retrospective observational study was conducted on a cohort of 1180 women with twin pregnancy delivered at a single tertiary hospital. Clinical data on maternal characteristics, and obstetric and neonatal outcomes were collected, and the analysis was perfor...
Source: Twin Research and Human Genetics - September 14, 2023 Category: Genetics & Stem Cells Authors: Silvia Vannuccini Sara Bolzonella Chiara Colucci Costanza Nicchi Noemi Strambi Mariarosaria Di Tommaso Source Type: research
Proximity hybridization regulated dual-mode ratiometric biosensor for estriol detection in pregnancy serum
Anal Chim Acta. 2023 Oct 16;1278:341689. doi: 10.1016/j.aca.2023.341689. Epub 2023 Aug 4.ABSTRACTSensitive and accurate determination of estriol level is vastly significant for the fetal growth and development. Herein, we constructed a dual-mode ratiometric biosensor for estriol assay combining the competitive immunoreaction, proximity hybridization with a two-step resonance energy transfer (RET) strategy. Estriol antibody and goat anti-rabbit antibody labeled DNA probes (Ab1-DNA1-Pt NPs and Ab2-DNA2) both hybridized with silver nanoclusters labeled DNA strands (H1-Ag NCs). Thus, the formed proximity hybridization enabled ...
Source: Analytica Chimica Acta - September 14, 2023 Category: Chemistry Authors: Yan Jiao Hongyuan Li Huan Wang Qiumei Feng Yongguang Gao Source Type: research
Rosuvastatin effects on the HDL proteome in hyperlipidemic patients
Acta Pharm. 2023 Sep 14;73(3):363-384. doi: 10.2478/acph-2023-0034. Print 2023 Sep 1.ABSTRACTThe advancements in proteomics have provided a better understanding of the functionality of apolipoproteins and lipoprotein-associated proteins, with the HDL lipoprotein fraction being the most studied. The focus of this study was to evaluate the HDL proteome in dyslipidemic subjects without an established cardiovascular disease, as well as to test whether rosuvastatin treatment alters the HDL proteome. Patients with primary hypercholesterolemia or mixed dyslipidemia were assigned to 20 mg/day rosuvastatin and blood samples were dr...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Ana Vavlukis Kristina Mladenovska Katarina Davalieva Marija Vavlukis Aleksandar Dimovski Source Type: research
Proximity hybridization regulated dual-mode ratiometric biosensor for estriol detection in pregnancy serum
Anal Chim Acta. 2023 Oct 16;1278:341689. doi: 10.1016/j.aca.2023.341689. Epub 2023 Aug 4.ABSTRACTSensitive and accurate determination of estriol level is vastly significant for the fetal growth and development. Herein, we constructed a dual-mode ratiometric biosensor for estriol assay combining the competitive immunoreaction, proximity hybridization with a two-step resonance energy transfer (RET) strategy. Estriol antibody and goat anti-rabbit antibody labeled DNA probes (Ab1-DNA1-Pt NPs and Ab2-DNA2) both hybridized with silver nanoclusters labeled DNA strands (H1-Ag NCs). Thus, the formed proximity hybridization enabled ...
Source: Analytica Chimica Acta - September 14, 2023 Category: Chemistry Authors: Yan Jiao Hongyuan Li Huan Wang Qiumei Feng Yongguang Gao Source Type: research
Prenatal Diagnosis and Molecular Cytogenetic Analyses of a de novo Deletion on Chromosome 4p16.3p15.33
Altern Ther Health Med. 2023 Sep 15:AT8915. Online ahead of print.ABSTRACTWolf-Hirschhorn syndrome (WHS) (OMIM 194190) is a contiguous gene syndrome with an estimated prevalence of around 1 in 50,000 births. The syndrome is caused by the deletion of a critical region (Wolf-Hirschhorn Syndrome Critical region-WHSCR) on chromosome 4p16.3. Its core features are typical facial gestalt, growth retardation, intellectual disability, developmental delay, and seizures. Prenatal diagnosis of WHS helps clinicians and parents make informed decisions about pregnancy management. In this research, a 31-year-old woman (gravida 1, para 0) ...
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Huili Luo Ruijie Chang Fangfang Liu Xia Gao Source Type: research
Proximity hybridization regulated dual-mode ratiometric biosensor for estriol detection in pregnancy serum
Anal Chim Acta. 2023 Oct 16;1278:341689. doi: 10.1016/j.aca.2023.341689. Epub 2023 Aug 4.ABSTRACTSensitive and accurate determination of estriol level is vastly significant for the fetal growth and development. Herein, we constructed a dual-mode ratiometric biosensor for estriol assay combining the competitive immunoreaction, proximity hybridization with a two-step resonance energy transfer (RET) strategy. Estriol antibody and goat anti-rabbit antibody labeled DNA probes (Ab1-DNA1-Pt NPs and Ab2-DNA2) both hybridized with silver nanoclusters labeled DNA strands (H1-Ag NCs). Thus, the formed proximity hybridization enabled ...
Source: Analytica Chimica Acta - September 14, 2023 Category: Chemistry Authors: Yan Jiao Hongyuan Li Huan Wang Qiumei Feng Yongguang Gao Source Type: research
Establishment and Validation of Risk Prediction Model for Postpartum Hemorrhage for Pregnant Women ≥35 Years of Age in Natural Delivery
CONCLUSIONS: The PPH risk-prediction model for vaginal delivery for pregnant women ≥35 years of age showed that a greater age, pregnancy-induced hypertension, a lower prelabor FIB, a longer third stage of labor, and a higher birth weight for the newborn were significantly related to the incidence of PPH and that its use could be clinically helpful.PMID:37708560
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Chunxue Yang Hongxia Wu Source Type: research
High Maternal Adiposity During Pregnancy Programs an Imbalance in the Lipidome and Predisposes to Diet-induced Hepatosteatosis in the Offspring
CONCLUSION: High maternal adiposity during pregnancy programs a susceptibility to diet-induced hepatosteatosis.PMID:37706282 | DOI:10.1042/BSR20231060
Source: Bioscience Reports - September 14, 2023 Category: Biomedical Science Authors: Taylor B Scheidl Jessica L Wager Larissa G Baker Amy L Brightwell Katrina M Melan Sebastian Larion Ousseynou Sarr T R Regnault Stefan J Urbanski Jennifer Thompson Source Type: research
Rosuvastatin effects on the HDL proteome in hyperlipidemic patients
Acta Pharm. 2023 Sep 14;73(3):363-384. doi: 10.2478/acph-2023-0034. Print 2023 Sep 1.ABSTRACTThe advancements in proteomics have provided a better understanding of the functionality of apolipoproteins and lipoprotein-associated proteins, with the HDL lipoprotein fraction being the most studied. The focus of this study was to evaluate the HDL proteome in dyslipidemic subjects without an established cardiovascular disease, as well as to test whether rosuvastatin treatment alters the HDL proteome. Patients with primary hypercholesterolemia or mixed dyslipidemia were assigned to 20 mg/day rosuvastatin and blood samples were dr...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Ana Vavlukis Kristina Mladenovska Katarina Davalieva Marija Vavlukis Aleksandar Dimovski Source Type: research
Prenatal Diagnosis and Molecular Cytogenetic Analyses of a de novo Deletion on Chromosome 4p16.3p15.33
Altern Ther Health Med. 2023 Sep 15:AT8915. Online ahead of print.ABSTRACTWolf-Hirschhorn syndrome (WHS) (OMIM 194190) is a contiguous gene syndrome with an estimated prevalence of around 1 in 50,000 births. The syndrome is caused by the deletion of a critical region (Wolf-Hirschhorn Syndrome Critical region-WHSCR) on chromosome 4p16.3. Its core features are typical facial gestalt, growth retardation, intellectual disability, developmental delay, and seizures. Prenatal diagnosis of WHS helps clinicians and parents make informed decisions about pregnancy management. In this research, a 31-year-old woman (gravida 1, para 0) ...
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Huili Luo Ruijie Chang Fangfang Liu Xia Gao Source Type: research
