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Total 69618 results found since Jan 2013.

Alteration of relative telomere length and telomerase reverse transcriptase expression in the granulosa cells of women during aging and assessment of < em > in vitro < /em > fertilization outcomes
Mol Med Rep. 2023 Nov;28(5):206. doi: 10.3892/mmr.2023.13093. Epub 2023 Sep 21.ABSTRACTTelomere attrition plays a critical role in the reproductive aging process in humans. Telomere length (TL) is typically regulated by telomerase, the main component of which is telomerase reverse transcriptase (TERT). The aim of the present study was to investigate the changes of relative TL (RTL) and TERT expression in granulosa cells (GCs) during aging and its association with reproduction. Clinical data on the frozen‑thawed embryo transfer cycles of older (>35 year old) and younger (≤35 year old) women from a single center over ...
Source: Molecular Medicine - September 21, 2023 Category: Molecular Biology Authors: Yan Hao Mingrong Lv Jing Peng Dan Kuang Zhihua Zhang Zhou Zhang Tingting Wang Bo Yang Zhaolian Wei Ping Zhou Zhiguo Zhang Yunxia Cao Source Type: research

Management of a Pregnant ALK-Positive Lung Cancer Patient With Alectinib-Induced Pneumonitis and Bilateral Globus Pallidus Necrosis Postpartum
Clin Lung Cancer. 2023 Aug 30:S1525-7304(23)00181-X. doi: 10.1016/j.cllc.2023.08.016. Online ahead of print.NO ABSTRACTPMID:37734987 | DOI:10.1016/j.cllc.2023.08.016
Source: Clinical Lung Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Tilmann Bochtler Petros Christopoulos Kai Schlamp Frank Winkler Alwin Kr ämer Source Type: research

Prevention of cardiovascular disease in young adults: Focus on gender differences. A collaborative review from the EAS Young Fellows
Atherosclerosis. 2023 Sep 19:117272. doi: 10.1016/j.atherosclerosis.2023.117272. Online ahead of print.ABSTRACTA steady rise in cardiovascular morbidity and mortality has been observed in young adults within the last decades. This trend corresponds to an increasing prevalence of traditional cardiovascular risk factors such as obesity and diabetes mellitus type 2 among young adults living in developed countries. Moreover, age-specific risk factors, such as substance abuse, contraceptive medication, and pregnancy-related diseases also correlate with an increased incidence of cardiovascular diseases. In this review, we discus...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Christina Antza Antonio Gallo Chrysoula Boutari Alexandra Ershova Kadri Murat Gurses Joanna Lewek Mirakhmadjon Mirmaksudov G ünther Silbernagel Joakim Sandstedt Anna Lebedeva Source Type: research

Relationships of pregnancy and postpartum diet quality with offspring birth weight and weight status through 12  months
CONCLUSIONS: Maternal diet quality during pregnancy (and during postpartum in mothers who breastfed for a longer duration) was inversely related to LGA and weight status indicators from birth through 12 months. Increasing maternal diet quality may have use for promoting healthy infant weight development.PMID:37731285 | DOI:10.1002/oby.23891
Source: Obesity - September 21, 2023 Category: Eating Disorders & Weight Management Authors: Leah Lipsky Jenna Cummings Anna Maria Siega-Riz Tonja Nansel Source Type: research

Rapid and sensitive point-of-care PTS-CRISPR assay for food safety monitoring of aflatoxin B1
Chem Commun (Camb). 2023 Sep 20. doi: 10.1039/d3cc03984f. Online ahead of print.ABSTRACTFood safety is crucial for human health, but its effective on-site monitoring remains a challenge. Pregnancy test strip (PTS) is the successful point-of-care testing (POCT) product of the highest market share in the world, with the cost as low as $0.10 per test. Herein, combined with the CRISPR (clustered regularly interspaced short palindromic repeats) system, PTS-CRISPR was for the first time introduced into food safety monitoring, for rapid and sensitive POCT of aflatoxin B1. The low-cost, easy-to-operate PTS-CRISPR is expected to br...
Source: Chemical Communications - September 20, 2023 Category: Chemistry Authors: Ziqiang Deng Jin Zhou Chaoqun Wang Jianyu Hu Rui Liu Yi Lv Source Type: research

Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on pregnancy and birth outcomes: A systematic review of experimental studies on non-human mammals
In conclusion, in utero RF-EMF exposure does not have a detrimental effect on fecundity and likely affects offspring health at birth, based on the meta-analysis of studies in experimental mammals on litter size and fetal weight, respectively. Regarding possible delayed effects of in utero exposure, RF-EMF probably does not affect offspring brain weight and may not decrease female offspring fertility; on the other hand, RF-EMF may have a detrimental impact on neurobehavioural functions, varying in magnitude for different endpoints, but these last findings are very uncertain. Further research is needed on the effects at birt...
Source: Environment International - September 20, 2023 Category: Environmental Health Authors: Eugenia Cordelli Lucia Ardoino Barbara Benassi Claudia Consales Patrizia Eleuteri Carmela Marino Maurizio Sciortino Paola Villani Martin H Brinkworth Guangdi Chen James P McNamee Andrew W Wood Lea Belackova Jos Verbeek Francesca Pacchierotti Source Type: research

Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats
CONCLUSIONS: These findings indicate that MOSA can exert prolonged adverse effects manifested as metabolic dysfunction in male offspring. Therefore, surveillance and management of OSA during pregnancy may be necessary to prevent and alleviate MAFLD in offspring.PMID:37730152 | DOI:10.1016/j.bbadis.2023.166889
Source: Biochimica et Biophysica Acta - September 20, 2023 Category: Biochemistry Authors: Ruhua Wang Wei Feng Yan Wang Yonghong Jiang Yiguang Lin Xueqing Chen Source Type: research

Sex differences in lipids: A life course approach
Atherosclerosis. 2023 Sep 1:117270. doi: 10.1016/j.atherosclerosis.2023.117270. Online ahead of print.ABSTRACTDifferences between men and women in lipids and lipoproteins are observed in distribution and trajectory from infancy to adulthood in the general population. However, these differences are more pronounced in hereditary lipid disorders such as familial hypercholesterolemia (FH) when absolute cholesterol levels are higher from birth onwards. In the early life course, girls compared to boys have higher low-density lipoprotein cholesterol (LDL-C) levels and total cholesterol, while high-density lipoprotein cholesterol ...
Source: Atherosclerosis - September 20, 2023 Category: Cardiology Authors: Kirsten B Holven Jeanine Roeters van Lennep Source Type: research

Rapid and sensitive point-of-care PTS-CRISPR assay for food safety monitoring of aflatoxin B1
Chem Commun (Camb). 2023 Sep 20. doi: 10.1039/d3cc03984f. Online ahead of print.ABSTRACTFood safety is crucial for human health, but its effective on-site monitoring remains a challenge. Pregnancy test strip (PTS) is the successful point-of-care testing (POCT) product of the highest market share in the world, with the cost as low as $0.10 per test. Herein, combined with the CRISPR (clustered regularly interspaced short palindromic repeats) system, PTS-CRISPR was for the first time introduced into food safety monitoring, for rapid and sensitive POCT of aflatoxin B1. The low-cost, easy-to-operate PTS-CRISPR is expected to br...
Source: Chemical Communications - September 20, 2023 Category: Chemistry Authors: Ziqiang Deng Jin Zhou Chaoqun Wang Jianyu Hu Rui Liu Yi Lv Source Type: research

Iodine-induced thyroid dysfunction: a scientometric study and visualization analysis
ConclusionOur scientometric analysis shows that investigations related to pregnant women, epidemiology surveys, and iodine deficiency are promising topics for future iodine-induced thyroid dysfunction research and highlights the important role of iodine on thyroid function.
Source: Frontiers in Endocrinology - September 20, 2023 Category: Endocrinology Source Type: research

Thyroglobulin antibodies in women with recurrent pregnancy loss: a systematic review and meta-analysis
Conclusions: Women with RPL were significantly more often TgAb-positive than women without RPL. Although there was a lack of studies reporting prospective outcomes, the findings of this study support the significance of awareness about the strong association between RPL and thyroid autoimmunity.PMID:37725583 | DOI:10.1089/thy.2023.0292
Source: Thyroid : official journal of the American Thyroid Association - September 19, 2023 Category: Endocrinology Authors: Perrine Shu Ting Huisman Jesper Krogh Claus Henrik Nielsen Henriette Svarre Nielsen Ulla Feldt-Rasmussen Sofie Bliddal Source Type: research

Prediction of large-for-gestational age at 36  weeks' gestation: two-dimensional vs three-Dimensional vs magnetic resonance imaging
CONCLUSION: At 36 WG, MRI performs better than 2D-US and 3D-US in predicting birthweight > 95th percentile at birth, especially in patients at high-risk for macrosomia, while 2D-US and 3D-US are comparable. For low-risk patients, the three modalities perform similarly. This article is protected by copyright. All rights reserved.PMID:37725758 | DOI:10.1002/uog.27485
Source: The Ultrasound Review of Obstetrics and Gynecology - September 19, 2023 Category: Radiology Authors: E Mazzone C Kadji M M Cannie D A Badr J C Jani Source Type: research

The association between labour epidural analgesia and postpartum depression in primiparous patients: a historical cohort study
CONCLUSION: This historical cohort study found an association between LEA and PPD among primiparous patients who subsequently had a second pregnancy in the same province. The findings call into question the hypothesis that LEA decreases the risk for PPD and further illustrates the complexities of PPD.PMID:37726496 | DOI:10.1007/s12630-023-02568-2
Source: Canadian Journal of Anaesthesia - September 19, 2023 Category: Anesthesiology Authors: Sherry Jin Allana Munro Ronald B George Source Type: research

Maternal Mental Health, COVID-19-Related Distress, and Disruptions in Lifestyle Behaviors Among Postpartum Mothers With a Previous Hypertensive Disorder of Pregnancy
CONCLUSION: Monitoring PTSD symptoms may be vital in supporting mothers with hypertensive disorders of pregnancy in making lifestyle changes to prevent cardiovascular disease.PMID:37723619 | DOI:10.1097/JCN.0000000000001038
Source: The Journal of Cardiovascular Nursing - September 19, 2023 Category: Nursing Authors: Jewel Scott Alisse Hauspurg Esa M Davis Samantha Bryan Janet M Catov Source Type: research

Nano-biomaterial Fibrinogen/P(LLA-CL) for prevention of intrauterine adhesion and restoration of fertility
In this study, we combined fibrinogen (Fg) and P(LLA-CL) by electrostatic spinning to form a stable nano-biomaterial Fg/P(LLA-CL), which can promote endometrial regeneration. After inducing physical injury to rat endometrium, we found that Fg/P(LLA-CL) membranes placed in the uterine cavities increased endometrial thickness and the number of glands after injury, while reducing the area of endometrial fibrosis. In addition, Fg/P(LLA-CL) increased neovascularization and decreased COL1A1 deposition. The expression of TGF-β1, a cytokine that promotes fibrosis, was down-regulated in the early stage of injury. Finally, fertilit...
Source: Biomed Res - September 19, 2023 Category: Research Authors: Sirui Song Siyu Wu Danzeng Meiduo Ping Chen Huaifang Li Hongbing He Source Type: research