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Infectious Disease: Epidemics
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Total 25019 results found since Jan 2013.
COVID-19 in 16 West African Countries: An Assessment of the Epidemiology and Genetic Diversity of SARS-CoV-2 after Four Epidemic Waves
This study has provided a good representation of the mutational profile and the prevalence of SARS CoV-2 lineages beyond the knowledge of the global epidemiology of the 16 African countries.PMID:37640294 | DOI:10.4269/ajtmh.22-0469
Source: Am J Trop Med Hyg - August 28, 2023 Category: Infectious Diseases Authors: Anna Julienne Selb é Ndiaye Mamadou Beye Aissatou Sow Gora Lo Abdou Padane Cheikh Sokhna Coumba Tour é Kane Philippe Colson Florence Fenollar Souleymane Mboup Pierre-Edouard Fournier Source Type: research
Neural network models for influenza forecasting with associated uncertainty using Web search activity trends
by Michael Morris, Peter Hayes, Ingemar J. Cox, Vasileios Lampos
Influenza affects millions of people every year. It causes a considerable amount of medical visits and hospitalisations as well as hundreds of thousands of deaths. Forecasting influenza prevalence with good accuracy can significantly help public health agencies to timely react to seasonal or novel strain epidemics. Although significant progress has been made, influenza forecasting remains a challenging modelling task. In this paper, we propose a methodological framework that improves over the state-of-the-art forecasting accuracy of influenza-like illness (I...
Source: PLoS Computational Biology - August 28, 2023 Category: Biology Authors: Michael Morris Source Type: research
Impact of the COVID-19 Pandemic on Esophagogastroduodenoscopy and Gastric Cancer Claims in South Korea: A Nationwide, Population-Based Study
CONCLUSION: Negative impact of the COVID-19 pandemic on EGD, gastric cancer, EGC, AGC, and gastric cancer operation was worst during the first surge of COVID-19, but decreased in the 2nd to 4th epidemic wave of the disease in 2020 and 2021.PMID:37634631 | PMC:PMC10462811 | DOI:10.3349/ymj.2023.0074
Source: Yonsei Medical Journal - August 27, 2023 Category: Universities & Medical Training Authors: Min Ah Suh Su Bee Park Min Seob Kwak Jin Young Yoon Jae Myung Cha Source Type: research
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals
This study lays the groundwork for identifying broad-acting, host-targeted therapies to reduce betacoronavirus replication that can be rapidly repurposed during future outbreaks and epidemics. The proteomics, phosphoproteomics, and MIB-MS datasets generated in this study are available in the Proteomics Identification Database (PRIDE) repository under project identifiers PXD040897 and PXD040901.PMID:37634194 | DOI:10.1021/acs.jproteome.3c00182
Source: Cell Research - August 27, 2023 Category: Cytology Authors: Ethan J Fritch Angie L Mordant Thomas S K Gilbert Carrow I Wells Xuan Yang Natalie K Barker Emily A Madden Kenneth H Dinnon Yixuan J Hou Longping V Tse Izabella N Castillo Amy C Sims Nathaniel J Moorman Premkumar Lakshmanane Timothy M Willson Laura E Herr Source Type: research
Coronavirus 2'-O-Methyltransferase: A Promising Therapeutic Target
We describe the attenuation phenotypes of NSP16-mutant CoVs, the roles of MDA5 and IFITs in sensing and antagonizing viral RNA lacking 2'O methylation, and the dependence on 2'-O-methylation in other virus families. We also detail the growing body of research into targeting 2'-O-methylation for therapeutics or as a platform for live attenuated vaccines. Beyond its role in RNA capping, NSP16 may have yet uncharacterized importance to CoV replication, highlighting the need for continued studies into NSP16 functions. Understanding the full contribution of NSP16 to the replicative fitness of CoVs will better inform the develop...
Source: Virus Research - August 27, 2023 Category: Virology Authors: Craig Schindewolf Vineet D Menachery Source Type: research
Impact of the COVID-19 Pandemic on Esophagogastroduodenoscopy and Gastric Cancer Claims in South Korea: A Nationwide, Population-Based Study
CONCLUSION: Negative impact of the COVID-19 pandemic on EGD, gastric cancer, EGC, AGC, and gastric cancer operation was worst during the first surge of COVID-19, but decreased in the 2nd to 4th epidemic wave of the disease in 2020 and 2021.PMID:37634631 | PMC:PMC10462811 | DOI:10.3349/ymj.2023.0074
Source: Yonsei Medical Journal - August 27, 2023 Category: Universities & Medical Training Authors: Min Ah Suh Su Bee Park Min Seob Kwak Jin Young Yoon Jae Myung Cha Source Type: research
