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Infectious Disease: Epidemics
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Total 25019 results found since Jan 2013.
Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research
Early COVID-Related pandemic impacts and subsequent opioid outcomes among persons receiving medication for opioid use disorder: a secondary data analysis of a Type-3 hybrid trial
CONCLUSIONS: Mitigating the effect of the pandemic on patients' interpersonal relationships and employment, and promoting greater infection control in opioid treatment programs, could be protective against negative opioid-related outcomes. Trial registration The present study describes secondary data analysis on a previously registered clinical trial: clinicaltrials.gov/ct2/show/NCT03931174.PMID:37705105 | PMC:PMC10500804 | DOI:10.1186/s13722-023-00409-7
Source: Addiction Science and Clinical Practice - September 13, 2023 Category: Addiction Authors: Tim Janssen Bryan R Garner Julia Yermash Kimberly R Yap Sara J Becker Source Type: research
Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research
Early COVID-Related pandemic impacts and subsequent opioid outcomes among persons receiving medication for opioid use disorder: a secondary data analysis of a Type-3 hybrid trial
CONCLUSIONS: Mitigating the effect of the pandemic on patients' interpersonal relationships and employment, and promoting greater infection control in opioid treatment programs, could be protective against negative opioid-related outcomes. Trial registration The present study describes secondary data analysis on a previously registered clinical trial: clinicaltrials.gov/ct2/show/NCT03931174.PMID:37705105 | PMC:PMC10500804 | DOI:10.1186/s13722-023-00409-7
Source: Addiction Science and Clinical Practice - September 13, 2023 Category: Addiction Authors: Tim Janssen Bryan R Garner Julia Yermash Kimberly R Yap Sara J Becker Source Type: research
Integrative transcriptomic and metabolomic analysis in mice reveals the mechanism by which ginseng stem-leaf saponins enhance mucosal immunity induced by a porcine epidemic diarrhea virus vaccination
Vaccine. 2023 Sep 11:S0264-410X(23)01085-X. doi: 10.1016/j.vaccine.2023.09.017. Online ahead of print.ABSTRACTPorcine epidemic diarrhea virus (PEDV) is a main cause of severe enteric disease in piglets, leading to millions of dollars lost annually in the global pig industry. Parenteral vaccination is limited in generating sufficient mucosal immunity, which is crucial for early defense against PEDV. Here, we orally administered ginseng stem-leaf saponins (GSLS) to mice before parenteral vaccination and found that GSLS significantly enhanced the phagocytosis of dendritic cells, promoted the activities of CD4+ T cells and inc...
Source: Vaccine - September 13, 2023 Category: Allergy & Immunology Authors: Fei Su Yin Xue Shiyi Ye Bin Yu Junxing Li Lihua Xu Xiufang Yuan Source Type: research
Dissemination of IncI plasmid encoding < em > bla < /em > < sub > CTX-M-1 < /sub > is not hampered by its fitness cost in the pig's gut
Antimicrob Agents Chemother. 2023 Sep 13:e0011123. doi: 10.1128/aac.00111-23. Online ahead of print.ABSTRACTMultiresistance plasmids belonging to the IncI incompatibility group have become one of the most pervasive plasmid types in extended-spectrum beta-lactamase-producing Escherichia coli of animal origin. The extent of the burden imposed on the bacterial cell by these plasmids seems to modulate the emergence of "epidemic" plasmids. However, in vivo data in the natural environment of the strains are scarce. Here, we investigated the cost of a blaCTX-M-1-IncI1 epidemic plasmid in a commensal E. coli animal strain, UB12-RC...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Margaux Allain Anne Claire Mah érault Benoit Gachet Caroline Martinez B énédicte Condamine M élanie Magnan Isabelle Kempf Erick Denamur Luce Landraud Source Type: research
Electronic Cigarette Exposure Disrupts Airway Epithelial Barrier Function and Exacerbates Viral Infection
Am J Physiol Lung Cell Mol Physiol. 2023 Sep 12. doi: 10.1152/ajplung.00135.2023. Online ahead of print.ABSTRACTThe use of electronic cigarettes (e-cigs), especially among teenagers, has reached alarming and epidemic levels, posing a significant threat to public health. However, the short- and long-term effects of vaping on the airway epithelial barrier are unclear. Airway epithelial cells are the forefront protectors from viruses and pathogens. They contain apical junctional complexes (AJC), which include tight junctions (TJs) and adherens junctions (AJs) formed between adjacent cells. Previously, we reported respiratory ...
Source: Am J Physiol Lung Ce... - September 12, 2023 Category: Respiratory Medicine Authors: Andjela Raduka Nannan Gao Robert L Chatburn Fariba Rezaee Source Type: research
