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Mandibular small cell osteosarcoma: a case report and review of literature
CONCLUSION: Accurate diagnosis is very important, and general practitioners should be aware of this entity considering that small cell osteosarcoma has a poor prognosis when compared to conventional osteosarcoma.PMID:37718329 | DOI:10.1186/s43046-023-00191-2
Source: J Egypt Natl Canc In... - September 17, 2023 Category: Cancer & Oncology Authors: Hatem Wael Amer Hana'a Hezam Algadi Shyma'a Ahmed Hamza Source Type: research
Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy
Light Sci Appl. 2023 Sep 18;12(1):231. doi: 10.1038/s41377-023-01275-3.ABSTRACTBeing the largest and most accessible organ of the human body, the skin could offer a window to diabetes-related complications on the microvasculature. However, skin microvasculature is typically assessed by histological analysis, which is not suited for applications to large populations or longitudinal studies. We introduce ultra-wideband raster-scan optoacoustic mesoscopy (RSOM) for precise, non-invasive assessment of diabetes-related changes in the dermal microvasculature and skin micro-anatomy, resolved with unprecedented sensitivity and det...
Source: Appl Human Sci - September 17, 2023 Category: Physiology Authors: Hailong He Nikolina-Alexia Fasoula Angelos Karlas Murad Omar Juan Aguirre Jessica Lutz Michael Kallmayer Martin F üchtenbusch Hans-Henning Eckstein Annette Ziegler Vasilis Ntziachristos Source Type: research
Mandibular small cell osteosarcoma: a case report and review of literature
CONCLUSION: Accurate diagnosis is very important, and general practitioners should be aware of this entity considering that small cell osteosarcoma has a poor prognosis when compared to conventional osteosarcoma.PMID:37718329 | DOI:10.1186/s43046-023-00191-2
Source: J Egypt Natl Canc In... - September 17, 2023 Category: Cancer & Oncology Authors: Hatem Wael Amer Hana'a Hezam Algadi Shyma'a Ahmed Hamza Source Type: research
Characterization of Multiple Resistance Genes of Escherichia coli Strains Isolated from Food and Clinical Samples
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):118-126. doi: 10.14715/cmb/2023.69.7.19.ABSTRACTMulti-drug resistance (MDR), which is formed by the development of antimicrobial resistance, which is one of the defense mechanisms in bacteria, has pushed human beings to constantly seek new antimicrobial agents in the fight against these microorganisms. Speed and precision are very important in identifying resistance in strains with MDR that reach humans in an open system through the consumption of contaminated food or water. The main aim of this study was the molecular characterization of ESBL gene variants (blaTEM, blaOXA,...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Birg ül Yelimlibağ Muhsin Aydin Source Type: research
Dynamics of γ-aminobutyric acid concentration in the human brain in response to short visual stimulation
CONCLUSION: The quick response of the observed GABA concentration to the short stimulus is most likely due to a release of GABA from vesicles followed by its packaging back into vesicles.PMID:37715877 | DOI:10.1007/s10334-023-01118-7
Source: Magma - September 16, 2023 Category: Radiology Authors: Alexey Yakovlev Alexandra Gritskova Andrei Manzhurtsev Maxim Ublinskiy Petr Menshchikov Anatoly Vanin Dmitriy Kupriyanov Tolib Akhadov Natalia Semenova Source Type: research
Label-free drug response evaluation of human derived tumor spheroids using three-dimensional dynamic optical coherence tomography
This study aims at demonstrating label-free drug-response-patterns assessment of different tumor spheroids and drug types by dynamic optical coherence tomography (D-OCT). The study involved human breast cancer (MCF-7) and colon cancer (HT-29) spheroids. The MCF-7 and HT-29 spheroids were treated with paclitaxel (Taxol; PTX) and the active metabolite of irinotecan SN-38, respectively. The drugs were applied with 0 (control), 0.1, 1, and 10 μM concentrations and the treatment durations were 1, 3, and 6 days. A swept-source OCT microscope equipped with a repeated raster scanning protocol was used to scan the spheroids. Logar...
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Ibrahim Abd El-Sadek Larina Tzu-Wei Shen Tomoko Mori Shuichi Makita Pradipta Mukherjee Antonia Lichtenegger Satoshi Matsusaka Yoshiaki Yasuno Source Type: research
Three-dimensional Anatomy of the Velopharyngeal Muscles in the Cleft Palate
CONCLUSIONS: With the help of Micro-CT technology, detailed anatomical features and the relationship between muscles could be visualized. In the specimen with cleft palate, muscles in the soft palate were associated with the pharyngeal muscles, which formed the 3D "velopharyngeal muscles complex." These findings provide anatomical evidence for muscle reconstruction in cleft palate repair.PMID:37715628 | DOI:10.1177/10556656231176867
Source: The Cleft Palate-Craniofacial Journal - September 16, 2023 Category: ENT & OMF Authors: Jiuli Zhao Hengyuan Ma Yongqian Wang Tao Song Di Wu Ningbei Yin Source Type: research
Take a walk on the KRAB side
Trends Genet. 2023 Sep 14:S0168-9525(23)00185-3. doi: 10.1016/j.tig.2023.08.003. Online ahead of print.ABSTRACTCanonical Krüppel-associated box (KRAB)-containing zinc finger proteins (KZFPs) act as major repressors of transposable elements (TEs) via the KRAB-mediated recruitment of the heterochromatin scaffold KRAB-associated protein (KAP)1. KZFP genes emerged some 420 million years ago in the last common ancestor of coelacanth, lungfish, and tetrapods, and dramatically expanded to give rise to lineage-specific repertoires in contemporary species paralleling their TE load and turnover. However, the KRAB domain displays se...
Source: Trends in Genetics : TIG - September 16, 2023 Category: Genetics & Stem Cells Authors: Olga Rosspopoff Didier Trono Source Type: research
Programmed cell death in Xanthomonas axonopodis pv. glycines is associated with modulation of gene expression resulting in altered states of motility, biofilm and virulence
Res Microbiol. 2023 Sep 14:104137. doi: 10.1016/j.resmic.2023.104137. Online ahead of print.ABSTRACTOne of the foremost report of apoptosis-like programmed cell death (PCD) came from Xanthomonas axonopodis pv. glycines (Xag), which displayed rapid post-exponential cell death in PCD inducing media (PIM) but not in a non-inducing media (PNIM). The current study aims to decipher for the first time, the advantages of the existence of PCD in this phytopathogenic microorganism. Analysis of RNA seq under inducing and non-inducing conditions, revealed differential expression of a number of genes related to key physiology of Xag, s...
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Nilantana C Bandyopadhyay Satyendra Gautam Source Type: research
Proanthocyanidin enhances the endogenous regeneration of alveolar bone by elevating the autophagy of PDLSCs
CONCLUSION: PA may activate autophagy by inhibiting PI3K/Akt/mTOR signaling pathway to promote the osteogenesis of PDLSCs and enhance endogenous alveolar bone regeneration.PMID:37715945 | DOI:10.1111/jre.13186
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Zhuo Liu Qilin Li Xiangyao Wang Yaxin Wu Zhixing Zhang Jing Mao Shiqiang Gong Source Type: research
Imaging manifestations of wandering spleen with torsion
We present a case of a male patient admitted to the emergency department with vomiting, nausea, and persistent lower abdominal pain. Computed tomography and ultrasound were performed and were used to diagnose a wandering spleen with torsion leading to splenic infarctions. Subsequently, laparoscopic surgery and pathology confirmed this diagnosis. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Ultrasound and computed tomography scans play a significant role in diagnosing WS and its complications, allowing an emergency physician to establish treatment options for WS.PMID:37716902 | DOI:10.1016/j.jemermed.2023.06.003
Source: Pain Physician - September 16, 2023 Category: Anesthesiology Authors: Tangna Wu Shaopiao Chen Lingling Qin Min Zhang Source Type: research
Europium(III) as luminescence probe for interactions of a sulfate-reducing microorganism with potentially toxic metals
Ecotoxicol Environ Saf. 2023 Sep 14;264:115474. doi: 10.1016/j.ecoenv.2023.115474. Online ahead of print.ABSTRACTMicroorganisms show a high affinity for trivalent actinides and lanthanides, which play an important role in the safe disposal of high-level radioactive waste as well as in the mining of various rare earth elements. The interaction of the lanthanide Eu(III) with the sulfate-reducing microorganism Desulfosporosinus hippei DSM 8344T, a representative of the genus Desulfosporosinus that naturally occurs in clay rock and bentonite, was investigated. Eu(III) is often used as a non-radioactive analogue for the trivale...
Source: Ecotoxicology and Environmental Safety - September 16, 2023 Category: Environmental Health Authors: Stephan Hilpmann Henry Moll Bj örn Drobot Manja Vogel Ren é Hübner Thorsten Stumpf Andrea Cherkouk Source Type: research
A foot structure study of new arch flexibility grading system based on three-dimensional arch volume
CONCLUSION: In cavus, rectus, and planus, different AVF accounts different percentage, but the difference is not statistically significant. AVF is evenly distributed in the arches of the feet at different heights. We further found the relationship between AHF and AVF is not significant. As a three-dimensional index, AVF may be able to describe the flexibility of the arch more comprehensively than AHF.PMID:37716873 | DOI:10.1016/j.cjtee.2023.09.002
Source: Chinese Journal of Traumatology - September 16, 2023 Category: Orthopaedics Authors: Jun Liu Miao Deng Wei Wang Xiang-Dong Liu Lun Tao Hong-Yi Xiang Yan Xiong Source Type: research
Computed tomography assessment of pelvic bone density: Associations with age and pelvic fracture in motor vehicle crashes
This study aimed to develop and validate a method to measure pelvic BMD in CT scans without a phantom, and examine associations of pelvic BMD with age and pelvic fracture incidence in seriously injured MVC occupants from the Crash Injury Research and Engineering Network (CIREN) study. A phantom-less muscle-fat calibration technique to measure pelvic BMD was validated using 45 quantitative CT scans with a bone calibration phantom. The technique was then used to measure pelvic BMD from CT scans of 252 CIREN occupants (ages 16+) in frontal MVCs who had sustained either abdominal or pelvic injury. Pelvic BMD was analyzed in re...
Source: Accident; Analysis and Prevention. - September 16, 2023 Category: Accident Prevention Authors: Ashley A Weaver Isaac N Ronning William Armstrong Anna N Miller Bahram Kiani R Shayn Martin Kristen M Beavers Joel D Stitzel Source Type: research
Evaluating hs-cTnI serum levels and cTnI gene expression compared with cardiac nuclear scan in patients with angina pectoris
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):98-103. doi: 10.14715/cmb/2023.69.7.16.ABSTRACTExercise stress can cause reversible myocardial ischemia in people with coronary artery disease (CAD). On the other hand, the new troponin biomarker with high sensitivity can detect faster and small amounts of troponin in blood circulation. The present study aimed to investigate the serum troponin level following exercise stress and the result of nuclear heart scans as the gold standard. For this purpose, 93 patients with stable angina and no history of known CAD and organic disease were included in this cross-sectional study. ...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Guifang Zhang Jiang Zhan Hong Lei HaiYan Zhu Xiaowei He Source Type: research
