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Total 11811 results found since Jan 2013.

Developmental venous anomaly as a rare cause of obstructive hydrocephalus: literature review and a case report.
CONCLUSION: Despite the fact that DVAs are asymptomatic, they may rarely cause obstructive hydrocephalus because of impairment in the CSF flow. They should be considered in the differential diagnosis of any patient presenting with obstructive hydrocephalus. ETV has been demonstrated as an effective treatment option in the management of obstructive hydrocephalus due to a DVA. PMID: 26439454 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgical Sciences - November 20, 2015 Category: Neurosurgery Tags: J Neurosurg Sci Source Type: research

Global surgery for pediatric hydrocephalus in the developing world: a review of the history, challenges, and future directions.
CONCLUSIONS Broader commitment from the pediatric neurosurgery community, increased funding, public education, surgeon training, and ongoing surgical innovation will be needed to meaningfully address the global burden of untreated hydrocephalus. PMID: 27798988 [PubMed - in process]
Source: Neurosurgical Focus - October 31, 2016 Category: Neurosurgery Authors: Muir RT, Wang S, Warf BC Tags: Neurosurg Focus Source Type: research

Surprisingly good outcome in antenatal diagnosis of severe hydrocephalus related to CCDC88C deficiency.
We present two families with CCDC88C-related recessive congenital hydrocephalus with children who had severe hydrocephalus. Those individuals who were shunted within the first few weeks of life, who did not require multiple surgical revisions, and who had a more distal truncating variant of the CCDC88C gene met their early childhood developmental milestones in some cases. This suggests that children with CCDC88C-related autosomal recessive hydrocephalus can have normal developmental outcomes under certain circumstances. We recommend CCDC88C analysis in cases of severe non-syndromic congenital hydrocephalus, especially when...
Source: European Journal of Medical Genetics - December 7, 2017 Category: Genetics & Stem Cells Authors: Wallis M, Baumer A, Smaili W, Jaouad IC, Sefiani A, Jacobson E, Bowyer L, Mowat D, Rauch A Tags: Eur J Med Genet Source Type: research

Frequency and treatment of hydrocephalus prior to and after posterior fossa tumor surgery in adult patients
ConclusionThe frequency of hydrocephalus prior to posterior fossa tumor surgery in adult patients is 21.4% and therefore much lower than in respective reports of pediatric patients. The risk of persistent hydrocephalus and newly developed hydrocephalus after tumor surgery was very low, too (5.7 and 2.1%, respectively). An ETV is not justified in every adult patient prior to posterior fossa tumor surgery.
Source: Acta Neurochirurgica - April 12, 2018 Category: Neurosurgery Source Type: research

Aquaporin 4 Silencing Aggravates Hydrocephalus Induced by Injection of Autologous Blood in Rats.
CONCLUSIONS Our study demonstrates that silencing AQP4 aggravates hydrocephalus, indicating that AQP4 protects against hydrocephalus. PMID: 29921834 [PubMed - in process]
Source: Medical Science Monitor - June 23, 2018 Category: Research Tags: Med Sci Monit Source Type: research

Healthcare Economics of Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage in the United States
AbstractHydrocephalus is one of the most common sequelae after aneurysmal subarachnoid hemorrhage (aSAH), and it is a large contributor to the condition ’s high rates of readmission and mortality. Our objective was to quantify the healthcare resource utilization (HCRU) and health economic burden incurred by the US health system due to post-aSAH hydrocephalus. The Truven Health MarketScan® Research database was used to retrospectively quantify the prevalence and HCRU associated with hydrocephalus in aSAH patients undergoing surgical clipping or endovascular coiling from 2008 to 2015. Multivariable longitudinal analysis w...
Source: Translational Stroke Research - March 12, 2019 Category: Neurology Source Type: research

Hydrocephalus Growth: Definition, Prevalence, Association with Poor Outcome in Acute Intracerebral Hemorrhage
ConclusionsHydrocephalus growth is defined by strongly predictive of short- or long-term mortality and poor outcome at 90  days, and might be a potential indicator for assisting clinicians for clinical decision-making.
Source: Neurocritical Care - November 10, 2020 Category: Neurology Source Type: research

Characteristics and management of hydrocephalus in adult patients with cerebellar glioblastoma: lessons from a French nationwide series of 118 cases
The objectives were to describe the occurence of hydrocephalus in a French nationwide series of adult patients with cGB, to identify the characteristics associated with hydrocephalus and to analyze the outcomes associated with the different surgical strategies, in order to propose practical guidelines. Consecutive cases of adult cGB patients prospectively recorded into the French Brain Tumor Database between 2003 and 2017 were screened. Diagnosis was confirmed by a centralized neuropathological review. Among 118 patients with cGB (mean age 55.9 years), 49 patients (41.5%) presented with pre-operative hydrocephalus. Thirtee...
Source: Neurosurgical Review - July 1, 2021 Category: Neurosurgery Source Type: research

Changes in computed tomography perfusion parameters and maximum contrast enhancement in patients having hydrocephalus with a ventriculoperitoneal shunt: a pilot study
CONCLUSIONS: Perfusion changes in patients with hydrocephalus after VP shunt were seen in the FWM and BG, which appears to be the result of the hydrocephalus reducing brain perfusion in the deep part of the brain. We concluded that SAH slows brain perfusion recovery.PMID:34781783 | DOI:10.1177/02841851211038807
Source: Acta Radiologica - November 16, 2021 Category: Radiology Authors: Dongjun Lee Eun Soo Kim Yul Lee Sang Min Lee Dae Young Yoon Young-Su Ju In-Bok Chang Source Type: research

Risk factors of postoperative hydrocephalus following decompressive craniectomy for spontaneous intracranial hemorrhages and intraventricular hemorrhage
Discussion: The incidence of hydrocephalus in patients who underwent delayed operation (more than 4 hours) was lower than that in patients who underwent an operation after less than 4 hours. nonsmoking groups also have lower incidence of hydrocephalus. Among patients who suffered from spontaneous supratentorial hemorrhage and need to receive emergent craniectomy, physicians should be reminded that postoperative hydrocephalus followed by ventriculoperitoneal shunting may be necessary in the future.
Source: Medicine - October 14, 2022 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

The ASPECT Hydrocephalus System: a non-hierarchical descriptive system for clinical use
AbstractIn patients with hydrocephalus, prognosis and intervention are based on multiple factors. This includes, but is not limited to, time of onset, patient age, treatment history, and obstruction of cerebrospinal fluid flow. Consequently, several distinct hydrocephalus classification systems exist. The International Classification of Diseases (ICD) is universally applied, but in ICD-10 and the upcoming ICD-11, hydrocephalus diagnoses incorporate only a few factors, and the hydrocephalus diagnoses of the ICD systems are based on different clinical measures. As a consequence, multiple diagnoses can be applied to individua...
Source: Acta Neurochirurgica - November 24, 2022 Category: Neurosurgery Source Type: research

A novel heterozygous variant of FOXJ1 in a Chinese female with primary ciliary dyskinesia and hydrocephalus: A case report and literature review
ConclusionThis is the first report of a de novo, autosomal dominant pattern ofFOXJ1 causing PCD combined with hydrocephalus in China. The patient's clinical symptoms were similar to those previously reported. WES confirmed that a novel variant ofFOXJ1 was the cause of the PCD combined with hydrocephalus, expanding the spectrum of the genotypes associated with this condition. Physicians should be aware of the correlation of hydrocephalus and PCD and test forFOXJ1 variants.
Source: Molecular Genetics & Genomic Medicine - July 20, 2023 Category: Genetics & Stem Cells Authors: Shiyang Gao, Qianwen Zhang, Biyun Feng, Shili Gu, Zhiying Li, Lianping Sun, Ru ‐en Yao, Tingting Yu, Yu Ding, Xiumin Wang Tags: CLINICAL REPORT Source Type: research

Subarachnoid Hemorrhage-Induced Hydrocephalus in Rats Brief Reports
Conclusions— SAH causes ventricular enlargement in a rat endovascular perforation model, with hydrocephalus occurring in 44% of animals at 24 hours. Rats with hydrocephalus had more severe SAH, intraventricular hemorrhage, and greater ventricular wall damage.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Okubo, S., Strahle, J., Keep, R. F., Hua, Y., Xi, G. Tags: Animal models of human disease, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Brief Reports Source Type: research