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Total 11811 results found since Jan 2013.

Hydrocephalus treatment in patients with craniosynostosis: an analysis from the Hydrocephalus Clinical Research Network prospective registry
CONCLUSIONS: This is the largest prospective study reported on children with craniosynostosis and hydrocephalus. Hydrocephalus in children with craniosynostosis most commonly occurs in syndromic patients and multisuture fusion. It is treated at varying ages; however, most patients undergo surgery for craniosynostosis prior to hydrocephalus treatment. While VPS treatment is performed more frequently, VPS and ETV are both reasonable options, with decreasing revision rates with increasing age, for the treatment of hydrocephalus associated with craniosynostosis.PMID:33794488 | DOI:10.3171/2021.1.FOCUS20979
Source: Neurosurgical Focus - April 1, 2021 Category: Neurosurgery Authors: Christopher M Bonfield Chevis N Shannon Ron W Reeder Samuel Browd James Drake Jason S Hauptman Abhaya V Kulkarni David D Limbrick Patrick J McDonald Robert Naftel Ian F Pollack Jay Riva-Cambrin Curtis Rozzelle Mandeep S Tamber William E Whitehead John R W Source Type: research

IJERPH, Vol. 19, Pages 5712: Somatic Development Disorders in Children and Adolescents Affected by Syndromes and Diseases Associated with Neurodysfunction and Hydrocephalus Treated/Untreated Surgically
Conclusions: Surgically treated hydrocephalus occurred in patients with cerebral palsy and neural tube defects, and untreated hydrocephalus was present only in patients with neural tube defects. Untreated hydrocephalus negatively changed the course of individual development in the studied group of children, in contrast to surgically treated hydrocephalus.
Source: International Journal of Environmental Research and Public Health - May 7, 2022 Category: Environmental Health Authors: Lidia Perenc Agnieszka Guzik Justyna Podg órska-Bednarz Mariusz Dru żbicki Tags: Article Source Type: research

Early Enteral Nutrition Can Reduce Incidence of Postoperative Hydrocephalus in Patients with Severe Hypertensive Intracerebral Hemorrhage
CONCLUSIONS Early EN administration, SAH, IVH, and preoperative GCS were associated with the occurrence of chronic hydrocephalus in severe HICH patients. Early EN administration may inhibit the inflammatory response of brain-gut axis, which in turn reduces chronic hydrocephalus occurrence.PMID:35655416 | DOI:10.12659/MSM.935850
Source: Medical Science Monitor - June 3, 2022 Category: Research Authors: Zhi Cai Kai Zhao Yu Li Xueyan Wan Chunlin Li Hongquan Niu Kai Shu Ting Lei Source Type: research

Baby girl receives shock cancer diagnosis months after family spot peculiar squint
DESPITE its apparent innocuousness, when the parents of nine-month-old Orla Kearney noticed that she had started to squint they decided to get it checked out. What they found turned both Orla's and their lives upside down.
Source: Daily Express - Health - August 19, 2022 Category: Consumer Health News Source Type: news

Fingerprint changes in CSF composition associated with different aetiologies in human neonatal hydrocephalus: glial proteins associated with cell damage and loss
Conclusions: Apart from CNPase, which is an enzyme, the markers investigated are intracellular intermediate filaments and would be present in CSF only if the cells are compromised and the proteins released. Raised GFAP observed in post-haemorrhagic hydrocephalus must reflect damage to astrocytes and ependyma. Raised MBP in post-haemorrhagic and spina bifida with hydrocephalus indicates damage to oligodendrocytes and myelin. Vimentin protein detected in some of the late-onset hydrocephalic samples indicates damage to glial and other progenitors and suggests this condition affects periventricular regions. The presence of CNP...
Source: Cerebrospinal Fluid Research - December 18, 2013 Category: Neurology Authors: Irum NaureenKhawaja WaheedAhsen RathoreSuresh VictorConor MallucciJohn GooddenShahid ChohanJaleel Miyan Source Type: research

Kaolin-induced chronic hydrocephalus accelerates amyloid deposition and vascular disease in transgenic rats expressing high levels of human APP.
CONCLUSIONS: Kaolin-hydrocephalus can accelerate intraneuronal Aβ40 accumulation and vascular pathology in tgAPP21 rats. In addition, disrupted CSF production and reduced CSF turnover results in impaired Aβ clearance and accelerated vascular pathology in chronic hydrocephalus. The high co-morbidity seen in NPH, AD and CVD is likely not to be an age-related coincidence, but rather a convergence of pathologies related to diminished CSF clearance. PMID: 25685319 [PubMed]
Source: Brain Research - February 19, 2015 Category: Neurology Authors: Silverberg GD, Miller MC, Pascale CL, Caralopoulos IN, Agca Y, Agca C, Stopa EG Tags: Fluids Barriers CNS Source Type: research

New concept of the pathogenesis and therapeutic orientation of acquired communicating hydrocephalus
In conclusion, the future research direction should be the prevention of hydrocephalus, which should take a long period from the immediate occurrence of brain injury to several months or even years after the injury.
Source: Neurological Sciences - April 25, 2016 Category: Neurology Source Type: research

Comparison of CSF Distribution between Idiopathic Normal Pressure Hydrocephalus and Alzheimer Disease ADULT BRAIN
CONCLUSIONS: The z-axial expansion of the lateral ventricle and compression of the brain just above the ventricle were the common findings in the parameters for differentiating idiopathic normal pressure hydrocephalus from Alzheimer disease.
Source: American Journal of Neuroradiology - July 13, 2016 Category: Radiology Authors: Yamada, S., Ishikawa, M., Yamamoto, K. Tags: ADULT BRAIN Source Type: research

Unruptured brain arteriovenous malformations and hydrocephalus: Case series and review of the literature
ConclusionsThe most common cause of hydrocephalus in unruptured brain AVMs is mechanical obstruction by the draining vein if it is located in a strategic position. Treatment of hydrocephalus alone or with associated treatment of the AVM is safe and effective.
Source: Journal of Clinical Neuroscience - April 2, 2019 Category: Neuroscience Source Type: research