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Total 11811 results found since Jan 2013.

The prognostic significance of surgically treated hydrocephalus in leptomeningeal metastases.
CONCLUSIONS: The leptomeningeal metastases were often associated with hydrocephalus and the surgical treatment was helpful in limited patients. The prognosis was related with RTOG-RPA class and treatment of local and systemic treatment. PMID: 24635931 [PubMed - in process]
Source: Clinical Lung Cancer - March 22, 2014 Category: Cancer & Oncology Authors: Jung TY, Chung WK, Oh IJ Tags: Clin Neurol Neurosurg Source Type: research

Incidence, Timing, and Predictors of Delayed Shunting for Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage
Conclusion Delayed hydrocephalus after SAH occurs rarely overall, but in a substantial proportion of patients who required temporary ventriculostomy during the initial hospitalization. These results support vigilant surveillance of patients after removal of a temporary ventriculostomy, given the potential of delayed hydrocephalus to impair recovery or even result in clinical deterioration following SAH.
Source: Neurocritical Care - December 18, 2014 Category: Neurology Source Type: research

Periventricular hyperintensity in children with hydrocephalus
Conclusion Our results strongly support the hypothesis that the halo finding in hydrocephalus is caused by structural changes rather than pulsatile CSF flow.
Source: Pediatric Radiology - March 17, 2015 Category: Radiology Source Type: research

Characteristics of intracranial pressure (ICP) waves and ICP in children with treatment-responsive hydrocephalus
Conclusions Children with either communicating or non-communicating hydrocephalus improving clinically after surgery presented with elevated MWA and mean ICP. In particular, the levels of MWA were raised to a magnitude seen when intracranial compliance is impaired. Hence, the present observations may support the idea that improvement of intracranial compliance can be an important mechanism by which shunts work in pediatric hydrocephalus.
Source: Acta Neurochirurgica - April 14, 2015 Category: Neurosurgery Source Type: research

Effects of Melatonin on the Cerebellum of Infant Rat Following Kaolin-Induced Hydrocephalus: a Histochemical and Immunohistochemical Study.
Abstract Hydrocephalus is a developmental disorder causing abnormally collected cerebrospinal fluid within the cerebral ventricles. It leads to bigger skulls and many dysfunctions related to the nervous system. Here, we addressed whether exogenous melatonin administration could reverse the clinical features of kaolin-induced hydrocephalus in infantile rats. A controlled double-blinded study was conducted in 2-week-old 45 Wistar albino rats, which were divided into three groups: Group A, the control group, received intracisternal sham injection with solely the needle insertion; group B, the hydrocephalus group, was...
Source: Cerebellum - April 24, 2016 Category: Neuroscience Authors: Uyanıkgil Y, Turgut M, Baka M Tags: Cerebellum Source Type: research

Endoscopic third ventriculostomy for treatment of adult hydrocephalus: long-term follow-up of 163 patients.
CONCLUSIONS ETV is an effective long-term treatment for selected adult patients with hydrocephalus. The overall ETV success rate when it was the primary treatment modality for adult hydrocephalus was approximately 87%, and 99% of patients experience symptomatic improvement after 2 ETVs. Patients in whom VP shunt surgery fails prior to an ETV have a 22% relative risk of ETV failure and an almost eightfold complication rate, although mostly minor, when compared with patients who undergo a primary ETV. Most ETV failures occur within the first 7 months of surgery in patients treated with primary ETV, but the time to failure is...
Source: Neurosurgical Focus - August 31, 2016 Category: Neurosurgery Authors: Isaacs AM, Bezchlibnyk YB, Yong H, Koshy D, Urbaneja G, Hader WJ, Hamilton MG Tags: Neurosurg Focus Source Type: research

Levels of selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in patients with hydrocephalus.
Authors: Czubowicz K, Głowacki M, Fersten E, Kozłowska E, Strosznajder RP, Czernicki Z Abstract <i>Cytokines are widely known mediators of inflammation accompanying many neurodegenerative disorders including normal pressure hydrocephalus (NPH). NPH is caused by impaired cerebrospinal fluid (CSF) absorption and treated by surgical shunt insertion. The early diagnosis of NPH is difficult because of various manifestations of the disease. One of the most promising research directions is biochemical CSF analysis. The aim of this study was to determine the CSF levels of cytokines. The levels of various cytokines ...
Source: Folia Neuropathologica - January 26, 2018 Category: Neurology Tags: Folia Neuropathol Source Type: research

Melatonin Attenuates Histopathological Changes in the Hippocampus of Infantile Rats with Kaolin-Induced Hydrocephalus
Conclusion: The present results demonstrate that the chronic hydrocephalus-induced histopathological changes in the hippocampus were partially reversible with melatonin treatment, suggesting its neuroprotective effects in infantile rats. However, these findings need to be confirmed by further experimental studies and clinical trials.Pediatr Neurosurg
Source: Pediatric Neurosurgery - May 29, 2018 Category: Neurosurgery Source Type: research

Arrested Hydrocephalus in Childhood: Case Series and Review of the Literature
Discussion Making a distinction between arrested and progressive hydrocephalus is fundamental, because of the opposed appropriate management. Any newly discovered case of hydrocephalus, not characterized by clear signs of progressive hydrocephalus, should benefit from active surveillance before any definitive decision is taken. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Neuropediatrics - June 22, 2018 Category: Neurology Authors: Hurni, Yannick Poretti, Andrea Schneider, Jacques Guzman, Raphael Ramelli, Gian Paolo Tags: Original Article Source Type: research

Comparing neurodevelopmental outcomes of children at 30 months of age by presence of hydrocephalus and shunt status among children enrolled in the MOMS trial.
CONCLUSION: No neurodevelopmental differences were noted with children enrolled in MOMS across the three hydrocephalus/shunt groups, although severity of hydrocephalus was associated with poorer outcomes. PMID: 30507586 [PubMed - as supplied by publisher]
Source: Journal of Pediatric Rehabilitation Medicine - December 7, 2018 Category: Rehabilitation Tags: J Pediatr Rehabil Med Source Type: research

Comprehensive analysis of differentially expressed profiles of long non-coding RNAs and messenger RNAs in kaolin-induced hydrocephalus.
CONCLUSIONS: In conclusion, our results provide candidate genes involved in hydrocephalus and suggest a new perspective on the modulation of lncRNAs in hydrocephalus. PMID: 30797995 [PubMed - as supplied by publisher]
Source: Gene - February 21, 2019 Category: Genetics & Stem Cells Authors: Shi YH, He XW, Liu FD, Liu YS, Hu Y, Shu L, Cui GH, Zhao R, Zhao L, Su JJ, Liu JR Tags: Gene Source Type: research

Detection of differentiated changes in gray matter in children with progressive hydrocephalus and chronic compensated hydrocephalus using voxel-based morphometry and machine learning.
CONCLUSIONS: Using VBM analysis, we characterized and visualized the GM changes in children with hydrocephalus. Machine learning results further confirmed that significant decrease of bilateral hippocampus/parahippocampus, insula and motor-related GM volume can serve as a specific neuroimaging index to distinguish the children with PH from the children with CH and controls at individual. The findings could help to aid the identification of individuals with PH in clinical practice. This article is protected by copyright. All rights reserved. PMID: 31654555 [PubMed - as supplied by publisher]
Source: Anatomical Record - October 25, 2019 Category: Anatomy Authors: Li Y, Tan Z, Wang Y, Wang Y, Li D, Chen Q, Huang W Tags: Anat Rec (Hoboken) Source Type: research

Intrathecal CSF dynamic measurements in Hydrocephalus associated with MMC – experience of the Republican center of Neurosurgery of Uzbekistan
ConclusionThe implantable shunt systems parameters were chosen before surgery in the surgical management of hydrocephalus in children with MMC are essential. This is important in order to prevent under or over drainage states, CSF leakage from the MMC sac. Management of hydrocephalus should be performed by considering MMC affecting craniospinal balance.
Source: Interdisciplinary Neurosurgery - January 1, 2020 Category: Neurosurgery Source Type: research

Investigating the Levels of Brain-Specific Proteins in Hydrocephalus Patients.
CONCLUSION: Experiments have shown that the levels of these proteins increase significantly in hydrocephalus patients compared to the healthy group. These three parameters can be considered as important markers in the diagnosis of hydrocephalus. PMID: 32691706 [PubMed - as supplied by publisher]
Source: Combinatorial Chemistry and High Throughput Screening - July 18, 2020 Category: Chemistry Authors: Guzelcicek A, Gönel A, Koyuncu I, Cigdem G, Kose D, Karadag M, Cadirci D Tags: Comb Chem High Throughput Screen Source Type: research

Volumetric quantification of aneurysmal subarachnoid hemorrhage independently predicts hydrocephalus and seizures.
CONCLUSIONS: Hemorrhage volume is an independent predictor of seizures and shunt-dependent hydrocephalus in patients with aSAH. Further evaluation of aSAH quantitative volumetric analysis may complement existing scales used in clinical practice and assist in patient prognostication and management. PMID: 33545677 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 5, 2021 Category: Neurosurgery Authors: Daou BJ, Khalsa SSS, Anand SK, Williamson CA, Cutler NS, Aaron BL, Srinivasan S, Rajajee V, Sheehan K, Pandey AS Tags: J Neurosurg Source Type: research