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Total 122032 results found since Jan 2013.
Identification and Analysis of Primary Cilia in the Corneal Endothelial Cells of Patients with Bullous Keratopathy
CONCLUSION: The findings in this study clearly demonstrate the expression of primary cilia in the CECs of patients afflicted with BK.PMID:37706487 | DOI:10.1080/02713683.2023.2259633
Source: Current Eye Research - September 14, 2023 Category: Opthalmology Authors: Hideto Deguchi Hidetoshi Tanioka Mako Watanabe Noriko Horiuchi Hideki Fukuoka Osamu Hieda Tsutomu Inatomi Shigeru Kinoshita Chie Sotozono Source Type: research
Immunopathological features of myopathy associated with small-to-medium-sized vessel vasculitis and differences from autoimmune myositis
CONCLUSIONS: Patients with vasculitis demonstrated mild myofiber damage based on the lower involvement of CD56/NCAM-expressing myofibers compared to those with AIM. Complement component deposits on the vessel walls and hypervascularity in the endomysium areas may be immunopathological features of vasculitic myopathy.PMID:37706291 | DOI:10.55563/clinexprheumatol/hpoapl
Source: Clinical and Experimental Rheumatology - September 14, 2023 Category: Rheumatology Authors: Shun Nomura Yasuhiro Shimojima Takanori Ichikawa Daigo Miyazaki Akinori Uruha Dai Kishida Yoshiki Sekijima Source Type: research
Bullous emphysema and breast surgery: could fascial blocks be the best strategy?
Minerva Anestesiol. 2023 Sep 13. doi: 10.23736/S0375-9393.23.17592-4. Online ahead of print.NO ABSTRACTPMID:37705432 | DOI:10.23736/S0375-9393.23.17592-4
Source: Minerva Anestesiologica - September 14, 2023 Category: Anesthesiology Authors: Gabriele DI Silvestre Paola Sciamanna Chiara Angeletti Franco Marinangeli Federica Venturoni Paolo Scimia Source Type: research
Design and synthesis of amino-substituted < em > N < /em > -arylpiperidinyl-based inhibitors of the (immuno)proteasome
Acta Pharm. 2023 Sep 14;73(3):441-456. doi: 10.2478/acph-2023-0032. Print 2023 Sep 1.ABSTRACTThe constitutive proteasome and the immunoproteasome represent validated targets for pharmacological intervention in the context of various diseases, such as cancer, inflammation, and autoimmune diseases. The development of novel chemical scaffolds of non-peptidic nature, capable of inhibiting different catalytically active subunits of both isoforms, is a viable approach against these diseases. Such compounds are also useful as leads for the development of biochemical probes that enable the studies of the roles of both isoforms in ...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Martina Gobec Ale š Obreza Marko Juki č Ana Baumgartner Nja Mihel čič Špela Potočnik Julija Virant Irena Mlinari č Ra ščan Stanislav Gobec Izidor Sosi č Source Type: research
Effect of Dupilumab on Generalized Verrucosis in Refractory Bullous Pemphigoid
Acta Derm Venereol. 2023 Sep 14;103:adv12324. doi: 10.2340/actadv.v103.12324.NO ABSTRACTPMID:37707294 | DOI:10.2340/actadv.v103.12324
Source: Acta Dermato-Venereologica - September 14, 2023 Category: Dermatology Authors: Qijun Wang Yue Ruan Fei Guo Haiqin Zhu Meng Pan Source Type: research
Bullous emphysema and breast surgery: could fascial blocks be the best strategy?
Minerva Anestesiol. 2023 Sep 13. doi: 10.23736/S0375-9393.23.17592-4. Online ahead of print.NO ABSTRACTPMID:37705432 | DOI:10.23736/S0375-9393.23.17592-4
Source: Minerva Anestesiologica - September 14, 2023 Category: Anesthesiology Authors: Gabriele DI Silvestre Paola Sciamanna Chiara Angeletti Franco Marinangeli Federica Venturoni Paolo Scimia Source Type: research
Effect of Dupilumab on Generalized Verrucosis in Refractory Bullous Pemphigoid
Acta Derm Venereol. 2023 Sep 14;103:adv12324. doi: 10.2340/actadv.v103.12324.NO ABSTRACTPMID:37707294 | DOI:10.2340/actadv.v103.12324
Source: Acta Derm Venereol A... - September 14, 2023 Category: Dermatology Authors: Qijun Wang Yue Ruan Fei Guo Haiqin Zhu Meng Pan Source Type: research
Cardiopulmonary bypass surgery-cold alert!
We report a case of CAs diagnosed intraoperatively during emergency mitral valve replacement.PMID:37706393 | PMC:PMC10284479 | DOI:10.4103/aca.aca_78_21
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Nazmeen I Sayed Shakuntala Basantwani Chetana Bhalerao Usha Nair Priyanka Navalkar Source Type: research
Swelling of the salivary glands and sicca symptoms in Kimura's disease, a rare rheumatological differential diagnosis with an indicatively high IgE serum level-A current overview after literature search
Z Rheumatol. 2023 Sep 14. doi: 10.1007/s00393-023-01411-9. Online ahead of print.ABSTRACTRheumatic and musculoskeletal diseases (RMD) include various diseases with sometimes rather different symptoms, some of which are locally confined and others show systemic features. Autoimmune phenomena, such as those occurring in Sjögren's syndrome, often cause symptoms such as xerostomia and xerophthalmia in association with inflammation of the salivary glands. The pathogenesis of these diseases is only partly clarified. This is similar to allergic diseases, which are otherwise clearly different with respect to the symptoms and path...
Source: Zeitschrift fur Rheumatologie - September 14, 2023 Category: Rheumatology Authors: J ürgen Braun Kirsten Karberg Source Type: research
Design and synthesis of amino-substituted < em > N < /em > -arylpiperidinyl-based inhibitors of the (immuno)proteasome
Acta Pharm. 2023 Sep 14;73(3):441-456. doi: 10.2478/acph-2023-0032. Print 2023 Sep 1.ABSTRACTThe constitutive proteasome and the immunoproteasome represent validated targets for pharmacological intervention in the context of various diseases, such as cancer, inflammation, and autoimmune diseases. The development of novel chemical scaffolds of non-peptidic nature, capable of inhibiting different catalytically active subunits of both isoforms, is a viable approach against these diseases. Such compounds are also useful as leads for the development of biochemical probes that enable the studies of the roles of both isoforms in ...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Martina Gobec Ale š Obreza Marko Juki č Ana Baumgartner Nja Mihel čič Špela Potočnik Julija Virant Irena Mlinari č Ra ščan Stanislav Gobec Izidor Sosi č Source Type: research
Swelling of the salivary glands and sicca symptoms in Kimura's disease, a rare rheumatological differential diagnosis with an indicatively high IgE serum level-A current overview after literature search
Z Rheumatol. 2023 Sep 14. doi: 10.1007/s00393-023-01411-9. Online ahead of print.ABSTRACTRheumatic and musculoskeletal diseases (RMD) include various diseases with sometimes rather different symptoms, some of which are locally confined and others show systemic features. Autoimmune phenomena, such as those occurring in Sjögren's syndrome, often cause symptoms such as xerostomia and xerophthalmia in association with inflammation of the salivary glands. The pathogenesis of these diseases is only partly clarified. This is similar to allergic diseases, which are otherwise clearly different with respect to the symptoms and path...
Source: Zeitschrift fur Rheumatologie - September 14, 2023 Category: Rheumatology Authors: J ürgen Braun Kirsten Karberg Source Type: research
IL-21, Not IL-17A, Exacerbates Murine Primary Biliary Cholangitis
In this study, we investigated the effects of Th17 effector cytokines, including interleukin (IL)-17A, IL-17F, and IL-21 in PBC using a xenobiotic-induced mouse model of autoimmune cholangitis (inducible chemical xenobiotic models of PBC) treated with cytokine-expressing adeno-associated virus. Our results showed that administration of IL-17A, the well-known main cytokine produced by Th17 cells, did not augment liver inflammation or fibrosis. In contrast, we noted IL-17A-treated mice had lower hepatic Th1 cell numbers and higher hepatic CD11b +Ly6G + polymorphonuclear myeloid-derived suppressor cell numbers. IL-17F did not...
Source: Clinical and Developmental Immunology - September 14, 2023 Category: Allergy & Immunology Authors: Chun-Wen Chan Hung-Wen Chen Yu-Wen Wang Chia-I Lin Ya-Hui Chuang Source Type: research
Identification and Analysis of Primary Cilia in the Corneal Endothelial Cells of Patients with Bullous Keratopathy
CONCLUSION: The findings in this study clearly demonstrate the expression of primary cilia in the CECs of patients afflicted with BK.PMID:37706487 | DOI:10.1080/02713683.2023.2259633
Source: Current Eye Research - September 14, 2023 Category: Opthalmology Authors: Hideto Deguchi Hidetoshi Tanioka Mako Watanabe Noriko Horiuchi Hideki Fukuoka Osamu Hieda Tsutomu Inatomi Shigeru Kinoshita Chie Sotozono Source Type: research
Immunopathological features of myopathy associated with small-to-medium-sized vessel vasculitis and differences from autoimmune myositis
CONCLUSIONS: Patients with vasculitis demonstrated mild myofiber damage based on the lower involvement of CD56/NCAM-expressing myofibers compared to those with AIM. Complement component deposits on the vessel walls and hypervascularity in the endomysium areas may be immunopathological features of vasculitic myopathy.PMID:37706291 | DOI:10.55563/clinexprheumatol/hpoapl
Source: Clinical and Experimental Rheumatology - September 14, 2023 Category: Rheumatology Authors: Shun Nomura Yasuhiro Shimojima Takanori Ichikawa Daigo Miyazaki Akinori Uruha Dai Kishida Yoshiki Sekijima Source Type: research
