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Total 1864 results found since Jan 2013.

Staged closure of a giant omphalocele with amnion preservation, modified technique.
Authors: Aljahdali AH, Al-Buainain HM, Skarsgard ED Abstract Closure of a giant omphalocele can be challenging. Preservation of the amnion in staged closure is not commonly practiced. Here, we describe 2 cases of giant omphalocele treated with a modified amnion preservation, staged closure technique. This paper demonstrates the feasibility and safety of this technique, and the versatility of amnion to adapt to an escharization strategy if closure is not achievable. PMID: 28397950 [PubMed - in process]
Source: Saudi Medical Journal - April 12, 2017 Category: Middle East Health Tags: Saudi Med J Source Type: research

Maternal Stressors and Social Support and Risks of Delivering Babies With Gastroschisis or Hypospadias.
We examined the association of maternal stressful life events and social support with risks of gastroschisis and hypospadias, using data from the National Birth Defects Prevention Study, a population-based case-control study of US births taking place in 2006-2011. We examined maternal self-reports of 7 life events and 3 sources of social support during the periconceptional period among mothers of 593 gastroschisis cases, 1,142 male hypospadias cases, and 4,399 nonmalformed controls. Responses to the questions on stressful life events were summed to form an index (higher is worse), as were responses to questions on social s...
Source: Am J Epidemiol - May 13, 2017 Category: Epidemiology Authors: Carmichael SL, Ma C, Tinker S, Shaw GM, National Birth Defects Prevention Study Tags: Am J Epidemiol Source Type: research

The conservative treatment of giant omphalocele by tanning with povidone iodine and aqueous 2% eosin solutions
Conclusion: The conservative treatment of giant omphalocele through the application of povidone iodine and aqueous eosine is effective and cost-effective. This procedure should be privileged in our limited resources Health centers where pediatric intensive care unit are lacking.
Source: Annals of Pediatric Surgery - July 1, 2017 Category: Surgery Tags: Original Articles Source Type: research

Fetal growth standards in gastroschisis: Reference values for ultrasound measurements
ConclusionsFetuses with gastroschisis show symmetrical growth deficits in the second and third trimesters, with normal UA Doppler velocimetry. These results reinforce the hypothesis that they are constitutionally smaller, yet not restricted due to placental insufficiency.
Source: Prenatal Diagnosis - November 7, 2017 Category: Perinatology & Neonatology Authors: Mariane Massaini Barbieri, Jo ão Renato Bennini, Marcelo Luís Nomura, Sirlei Siani Morais, Fernanda Garanhani Surita Tags: ORIGINAL ARTICLE Source Type: research

Nutrition Delivery and Growth Outcomes in Infants With Gastroschisis.
CONCLUSION: Infants with gastroschisis are dependent on PN and have a significant decline in WAZ during their hospital stay, predicted by prematurity and CLABSI. Efforts to prevent CLABSI and optimize enteral autonomy must be prioritized in this cohort. PMID: 29338079 [PubMed - as supplied by publisher]
Source: JPEN Journal Of Parenteral And Enteral Nutrition - January 8, 2018 Category: Nutrition Authors: Hong CR, Zurakowski D, Fullerton BS, Ariagno K, Jaksic T, Mehta NM Tags: JPEN J Parenter Enteral Nutr Source Type: research

Is omphalocele a non-specific malformation in New Zealand White rabbits?
Publication date: June 2018 Source:Reproductive Toxicology, Volume 78 Author(s): George P. Daston, Manon Beekhuijzen We evaluated the incidence of omphalocele, a malformation that occurs sporadically in many studies. We assembled data on external malformations using all treatment groups from every study published in three major journals over the past 35 years using New Zealand White rabbits. Fifty-eight papers were included: 4905 litters and 36,977 fetuses. Omphalocele was reported in 43% and was among the most common defects, occurring at a rate of 1.10% (litter) and 0.16% (fetus). The defect did not appear to be treatme...
Source: Reproductive Toxicology - April 10, 2018 Category: Toxicology Source Type: research

The factors associated with successful early enteral feeding in gastroschisis
ConclusionSeveral factors were found to be associated with successful early enteral feeding. The modifiable factors found in this study were surgery within 10  h, early postoperative extubation within 4 days, and feeding started before 10 days of life. These will guide the management of gastroschisis to achieve successful early enteral feeding.
Source: Pediatric Surgery International - May 25, 2018 Category: Surgery Source Type: research

A clinical-pathogenetic approach on associated anomalies and chromosomal defects supports novel candidate critical regions and genes for gastroschisis
ConclusionsOur findings suggest that gastroschisis may result from the interaction of several chromosomal regions in an additive manner as a pool of candidate genes were identified from critical regions supporting a role for vascular disruption, thrombosis, and mesodermal deficiency in the pathogenesis of gastroschisis.
Source: Pediatric Surgery International - August 9, 2018 Category: Surgery Source Type: research

Early Life Incidence of Gastrointestinal and Respiratory Infections in Children With Gastroschisis: A Cohort Study
Objectives: Survival in infants with gastroschisis is increasing although little is known about early childhood morbidity. In the context of a hypothesized link between the gastrointestinal (GI) tract and immune function, this study explores rates of GI and respiratory infections in children with gastroschisis. Methods: We conducted a population-based retrospective cohort study using data from the Health Improvement Network, a large database of UK primary care medical records. We identified children born from 1990 to 2013, and extracted follow-up data to their fifth birthday. We calculate incidence rates (IR) of GI an...
Source: Journal of Pediatric Gastroenterology and Nutrition - October 25, 2018 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Gastroschisis and Autism —Dual Canaries in the Californian Coalmine—Reply
In Reply In their letter, Reece and Hulse suggest there may be a correlation between cannabis consumption and gastroschisis based on the high consumption of cannabis in counties where we have found high rates of gastroschisis. To be clear, Reece and Hulse are inaccurate in their statement that we “found rurality was a risk factor for cannabis use.” Instead, we found higher rates of gastroschisis in rural counties. In a follow-up study, we found that fetal exposure to drugs other than alcohol, cocaine, narcotics, or hallucinogenics (odds ratio [OR], 3.27; 95% CI, 1.05-10.15;P = .04) and other noxious substances (OR,...
Source: JAMA Surgery - February 6, 2019 Category: Sports Medicine Source Type: research

Risk Factors for Inpatient Mortality in Patients Born with Gastroschisis in the United States
Conclusion Inpatient mortality for neonates with gastroschisis is relatively low. Even after correcting for illness severity, race, health insurance status, and domicile appear to play a role in mortality disparities. Opportunities may exist to further decrease mortality in at-risk populations. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - August 13, 2019 Category: Perinatology & Neonatology Authors: Lamoshi, Abdulraouf Rothstein, David H. Tags: Original Article Source Type: research

Repair of ruptured omphalocele sac in the neonatal period and beyond
We report a case where a ruptured sac of giant omphalocele was ingeniously sutured to restore its integrity, and conservative management continued. The giant omphalocele later became a huge ventral hernia and was gradually reduced and primary closure was achieved with multiple surgeries over a period of 4 years.
Source: Journal of Indian Association of Pediatric Surgeons - November 26, 2019 Category: Surgery Authors: Nidhi Sugandhi Manoj Saha Veereshwar Bhatnagar Anjan Kumar Dhua Source Type: research

Predicting Morbidity and Mortality in Neonates Born With Gastroschisis
Gastroschisis is an increasingly common congenital abdominal wall defect. Due to advances in neonatal critical care and early surgical management, mortality from gastroschisis and associated complications has decreased to less than 10% in most series. However, it has been recognized that the outcome of gastroschisis has a spectrum and that the disorder affects a heterogeneous cohort of neonates. The goal of this study is to predict morbidity and mortality in neonates with gastroschisis using clinically relevant variables.
Source: Journal of Surgical Research - August 13, 2019 Category: Surgery Authors: Steven L. Raymond, Russell B. Hawkins, Shawn D. St. Peter, Cynthia D. Downard, Faisal G. Qureshi, Elizabeth Renaud, Paul D. Danielson, Saleem Islam Tags: Pediatric/Congenital/Developmental Source Type: research

Feeding Tolerance, Intestinal Motility, and Superior Mesenteric Artery Blood Flow in Infants with Gastroschisis.
CONCLUSION: Increased SMA blood flow at the time of abdominal wall closure is positively correlated with feeding tolerance, suggesting the importance of initial intestinal perfusion in the pathophysiology for feeding intolerance and intestinal dysmotility in gastroschisis. PMID: 31851996 [PubMed - as supplied by publisher]
Source: Neonatology - December 17, 2019 Category: Perinatology & Neonatology Authors: Williams SL, Tkach JA, Rattan MS, South AP, Wessel J, Kingma PS Tags: Neonatology Source Type: research

Giant Omphalocele Complicated by 9P Minus Syndrome.
Authors: Alexander G, Silva J, Curi B, Yancy J, Bogojevic A, Gaither K Abstract Omphalocele is characterized as a ventral wall defect in which there exists a midline herniation of abdominal viscera into the base of the umbilical cord. Fetuses with a diagnosis of this entity are at a significantly increased risk of having an aneuploidy, additional anomalies, or associations with other syndromes such as Beckwith Wiederman. Secondary to these interconnections, there is an elevated risk of fetal loss in affected pregnancies. Detection of concordant abnormalities, appropriate genetic counseling, and involvement of pedia...
Source: Journal of the National Medical Association - August 5, 2020 Category: General Medicine Tags: J Natl Med Assoc Source Type: research