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Stressed Caregiver Can Increase Anxiety in Someone with Dementia
Photo credit Tim Doerfler
Dear Carol: My mom’s been living with Alzheimer’s for several years and Dad refuses to get any help with her. My sister and I have begged him to place Mom in memory care because the facilities where they live are good, but he has always adored her and feels like he must be her protector. We’re afraid for both of them because while he means well, her care is getting too difficult. He still says the right words, but his body language shows his stress level is high and he’s becoming impatient which is unlike him. I’m sure his stress is affecting Mom, too, and making her more anxious. That, ...
Source: Minding Our Elders - May 30, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Has Incontinence Changed Your Life? Sharing Your Story Can Help Normalize the Condition
A young man kicked off the Egosan search for others who were willing to share their stories about what led to their incontinence. For Matt, it was a car accident at age 22. For many, it's some type of cancer treatment or nerve damage from a disease. Whatever the reason, shame needs to be eliminated in order to truly get on with their lives.
Read more about Matt and how he learned to cope with this dramatic change in his young life:
Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.” ...Craig W...
Source: Minding Our Elders - May 25, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Fight Aging! Newsletter, May 24th 2021
In conclusion, we showed that addition of resistance exercise training, but not dietary EAAs, to the myostatin inhibition further increased muscle mass through the attenuation of muscle protein breakdown with proportionate improvements in muscle strength. Interestingly, addition of dietary EAAs to the myostatin inhibition with or without resistance exercise training improved muscle quality. Thus, dissection of the underlying mechanisms behind the combined positive effect of dietary EAAs and resistance exercise training on muscle mass and quality can shed light on the discovery of effective therapeutics against muscle wasti...
Source: Fight Aging! - May 23, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Critiquing the Hallmarks of Aging
The biggest problem I see with the Hallmarks of Aging paper is not really the fault of its authors, but rather that a sizable part of the research community now takes that list of aging associated mechanisms as a guide to points of intervention in aging. Unlike the SENS view of aging, a list of mechanisms in aging that preceded the Hallmarks paper by more than a decade, the Hallmarks were not established to be a list of root causes of aging, and were never intended to be taken as such.
In the case of SENS, wherein a great deal of thought has gone into identifying mechanisms that are root causes of aging, one can pro...
Source: Fight Aging! - May 20, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, May 17th 2021
This study is consistent with previous evidence showing that inflammaging, or age-related inflammation, is naturally heightened in the nervous system. Moreover, the authors disproved their hypothesis that anti-inflammatory microglia-specific genes are responsible for the elevated inflammatory response in aged brains since the expression of anti-inflammatory mediators was elevated in middle-aged brains following infection. Thus, the cause for the increase in pro-inflammatory genes remains to be elucidated.
Mixed Results in Animal Studies of Gene Therapy Targeting Axonal Regrowth
https://www.fightaging.org/archiv...
Source: Fight Aging! - May 16, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, May 10th 2021
This study suggests that some of those changes contribute to age-related hypertension, providing yet another reason to put resources into the near term development of therapies that can reverse the aging of the gut microbiome, such as flagellin vaccination or fecal microbiota transplantation.
"Previous studies from our lab have shown that the composition of the gut microbiota in animal models of hypertension, such as the SHRSP (spontaneously hypertensive stroke-prone) rat model, is different from that in animals with normal blood pressure. Further, transplanting dysbiotic gut microbiota from a hypertensive animal ...
Source: Fight Aging! - May 9, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cerebral hemodynamics in AF : ” Irregularly irregular ” brain perfusion and risk of “ dementia cordis ”
No doubt, the heart is a biological wonder with its non-stop pump function. Still, it cannot function as a continuous rotary pump like the electrical motors do. It has no other option but to contract in a pulsatile manner. However, the mean pressure in circulation is fairly constant, flow is kept continuous, and fairly laminar. This is made possible by the built-in elastic pressure in the aorta and the poorly understood but vitally important parameter vascular tone. Aging widens the pulse pressure due to dissipation of vascular tone. Atrial fibrillation adds new bizarre dynamism to this pulsatility and challenges the aorti...
Source: Dr.S.Venkatesan MD - May 4, 2021 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized affirm race trial atrial fibrialltion rate vs rhythm control atrial fibrillation cerebral bllod flow in atrial fibrillation nir spectroscopy in atrial fibrillation Source Type: blogs
Sharing Personal Stories Is a Powerful Way to End Disease Stigma: Read On
Whether you live with mental illness, dementia, a physical disability, or even incontinence, you are bound to face varying degrees of stigma when encountering the greater population. I believe much of this stems from the underlying (and usually unrecognized) read that many people have that this could happen to them or someone they love. In my opinion, the best way to battle this stigma is for brave people to go public with their challenges and show others that we are the same people with or without our disease or injury or simply a different way of functioning.
Read more on Egosancares blog to learn about how...
Source: Minding Our Elders - May 4, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
It's Bladder Cancer Awareness Month: Are You At Risk?
Bladder cancer is not overly common but it's not a rare disease, either. The American Cancer Society estimates that there will be 83,730 new cases this year. While most of them are treatable if caught reasonably early, both the disease and the treatments can involve varying degrees of incontinence.
Continue reading on Egosancare's blog to learn more about the risks and signs of bladder cancer as well as side effects of different treatments:
Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.” ....
Source: Minding Our Elders - May 3, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Fight Aging! Newsletter, May 3rd 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 2, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, April 26th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 25, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, April 19th 2021
In conclusion, airway pressure treatment and adherence are independently associated with lower odds of incident AD diagnoses in older adults. Results suggest that treatment of OSA may reduce risk of subsequent dementia.
Source: Fight Aging! - April 18, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, April 12th 2021
In conclusion, the MR exhibited the protective effects against age-related behavioral disorders, which could be partly explained by activating circulating FGF21 and promoting mitochondrial biogenesis, and consequently suppressing the neuroinflammation and oxidative damages. These results demonstrate that FGF21 can be used as a potential nutritional factor in dietary restriction-based strategies for improving cognition associated with neurodegeneration disorders.
Senescent T Cells Cause Changes in Fat Tissue that are Harmful to Long-Term Health
https://www.fightaging.org/archives/2021/04/senescent-t-cells-cause-...
Source: Fight Aging! - April 11, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A New Model Suggests a Higher Burden of Death Due to Particulate Air Pollution
This study demonstrates that the fossil fuel component of PM2.5 contributes a large mortality burden. The steeper concentration-response function slope at lower concentrations leads to larger estimates than previously found in Europe and North America, and the slower drop-off in slope at higher concentrations results in larger estimates in Asia.
Source: Fight Aging! - April 5, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, April 5th 2021
In this study, the research team designed a way to identify small molecules that improve the function of ABCA1 in the body while avoiding unwanted effects to the liver. The researchers honed in on a specific small molecule, CL2-57, due to its ability to stimulate ABCA1 activity with positive effects on liver and plasma triglycerides. The use of this compound showed improved glucose tolerance and insulin sensitivity, as well as reduced weight gain, among other beneficial effects.
Age-Related Upregulation of Autophagy as a Possible Contribution to Bat Longevity
https://www.fightaging.org/archives/2021/04/age-rela...
Source: Fight Aging! - April 4, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
