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How to Survive a Hurricane with an Alzheimer's Patient
Six of my most important tips for dealing with an Alzheimer's patient during a hurricane.By Bob DeMarcoAlzheimer's Reading RoomI took care of my mom, Dotty, for eight and a half years, 3,112 days.My mom lived with Alzheimer's disease.We survived 2 hurricanes together including monsterhurricane Wilma. A category 3 hurricane when it reached our home in Delray Beach, Florida.Here are 6 of my most important tips for dealing with an Alzheimer's patient during a hurricane.12 Ways to Control CareGiver Stress and SadnessListen Now or Continue ReadingSubscribe to the Alzheimer's Reading RoomEmail:#1 It's Not Their FaultMy mom acted...
Source: Alzheimer's Reading Room, The - September 1, 2019 Category: Neurology Tags: alzheimers care Alzheimers Disease alzheimers help alzheimers hurricane care of dementia patients florida disaster hurricane alzheimers natural disaster Source Type: blogs

Fight Aging! Newsletter, September 2nd 2019
In conclusion, in the absence of obesity, visceral adipose tissue possesses a pronounced anti-inflammatory phenotype during aging which is further enhanced by exercise. Methods of Inducing Cellular Damage are Rarely Relevant to Aging, and the Details Matter https://www.fightaging.org/archives/2019/08/methods-of-inducing-cellular-damage-are-rarely-relevant-to-aging-and-the-details-matter/ One of the major challenges in aging research is determining whether or not models of cellular or organismal damage and its consequences are in any way relevant to the natural processes of aging. One can hit a brick with...
Source: Fight Aging! - September 1, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 26th 2019
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - August 25, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How Do You Tell Someone With Dementia When a Loved One Has Died?
Photo credit Christian Newman ...My friend can be forgiven for dragging her feet. Her mother has been told often that the brother was ill. It was new information to the mother each time. There was no reason for the daughter to think that the telling of her uncle's death was not going to shock her mother all over again. She seriously thought of not mentioning it. It's not as if a visit was expected. She asked me what I thought. Read the full article on HealthCentral to learn more about how (or if) to tell someone that their spouse or other loved one has died: Carol Bradley Bursack is the Candid Caregiver MedicareFAQ – Med...
Source: Minding Our Elders - August 7, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

How To Minimize Grief for a Surviving Spouse Living with Dementia
Photo credit Jeremy Wong Dementia and the loss of a spouse are sad and challenging enough on their own, but when they coincide, the result can be truly heartbreaking. For many adult children, deciding whether to inform a cognitively impaired parent that their spouse has died is a serious and often recurring struggle. For someone who has not experienced such a dilemma, this would appear to be a no-brainer. However, as with many dementia-related quandaries, the question and answer are far more complex for those facing this reality. Read the full article on Agingcare to learn more about how you can try to minimize grief for y...
Source: Minding Our Elders - August 2, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Quality of life for Stroke Survivors and People with Alzheimer's Improved Through the Arts
Photo credit Matthieu-a-b ..."Patients who appreciated music, painting and theatre recovered better from their stroke than patients who did not"Patients interested in art had better general health, found it easier to walk, and had more energy. They were also happier, less anxious or depressed, and felt calmer. They had better memory and were superior communicators (speaking with other people, understanding what people said, naming people and objects correctly)." Read the full article on HealthCentral to learn more about how music can improve life quality for people who have had a stroke or who live with dementia:  &#...
Source: Minding Our Elders - August 1, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Fight Aging! Newsletter, July 29th 2019
In this study we show, for the first time, significant alterations in cholesterol efflux capacity in adolescents throughout the range of BMI, a relationship between six circulating adipocyte-derived EVs microRNAs targeting ABCA1 and cholesterol efflux capacity, and in vitro alterations of cholesterol efflux in macrophages exposed to visceral adipose tissue adipocyte-derived EVs acquired from human subjects. These results suggest that adipocyte-derived EVs, and their microRNA content, may play a critical role in the early pathological development of ASCVD. Commentary on the Developing UK Government Position on Hea...
Source: Fight Aging! - July 28, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

About the Alzheimer's Reading Room
The Award Winning Alzheimer ’s Reading Room Knowledge Base is considered to be the highest quality, deepest collection, of information on Alzheimer’s and dementia in the world. Ranked #1 by Healthline for 7 straight years (2012-2018).The goal of the Alzheimer's Reading Room is to help everyone to better understand, cope, and communicate with a person living with dementia.The Alzheimer's Reading Room is the publisher of high quality expert content and news for the Alzheimer's and dementia community.No one does it better than us! The Alzheimer's Reading Room operates for the benefit of society and the Alzheimer's co...
Source: Alzheimer's Reading Room, The - July 26, 2019 Category: Neurology Tags: #alzheimersworld Alzheimers Dementia alzheimers knowledge alzheimers reading room caregivers support Source Type: blogs

The Role of mTOR as a Regulator of Lifespan
The mTOR gene is deeply involved in the regulation of cellular activities in response to nutrient sensing. It is also implicated in the many, many changes that occur to slow aging in response to a restricted calorie intake, including processes known to be important to aging such as mitochondrial function and cellular senescence. Given that most research to date on intervention in the aging process has focused on the calorie restriction response and related upregulation of stress response mechanisms, it is no surprise that mTOR has attracted a lot of attention. The first mTOR inhibitor drugs are already going through clinic...
Source: Fight Aging! - July 23, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, July 22nd 2019
This study elucidates the potential to use mitochondria from different donors (PAMM) to treat UVR stress and possibly other types of damage or metabolic malfunctions in cells, resulting in not only in-vitro but also ex-vivo applications. Gene Therapy in Mice Alters the Balance of Macrophage Phenotypes to Slow Atherosclerosis Progression https://www.fightaging.org/archives/2019/07/gene-therapy-in-mice-alters-the-balance-of-macrophage-phenotypes-to-slow-atherosclerosis-progression/ Atherosclerosis causes a sizable fraction of all deaths in our species. It is the generation of fatty deposits in blood vessel...
Source: Fight Aging! - July 21, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Mainstream View of the Longevity Industry
This popular science article from the AARP is representative of the sort of outsider's view of the longevity industry that is presently dominant. On the one hand, it is good that the media and advocacy organizations such as AARP are finally talking seriously about treating aging as a medical condition. On the other hand, the author looks at two of the most popular areas of development, mTOR inhibitors and senolytics, in a way that makes them seem more or less equivalent, and then further adds diet and exercise as another equivalent strategy. This will be continuing issue, I fear. People, as a rule, don't think about size o...
Source: Fight Aging! - July 17, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Spectrum of Hope: An Interview About Alzheimer's
...In tandem with this effort was a quiet revolution doggedly moving forward.  Long championed by Dr. Bill Thomas of Changing Aging among others, the thinking behind this movement has always been to recognize that people living with Alzheimer’s and other dementia were first and foremost people. Developing dementia doesn’t take away your individuality or humanity any more than developing cancer or diabetes. Therefore, rather than concentrate only on drugs, we need to help caregivers – and yes professionals – better understand how to help people living with dementia cope with the negative aspects of...
Source: Minding Our Elders - July 7, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Fight Aging! Newsletter, July 8th 2019
In this study, we identify a link between members of the genus Veillonella and exercise performance. We observed an increase in Veillonella relative abundance in marathon runners postmarathon and isolated a strain of Veillonella atypica from stool samples. Inoculation of this strain into mice significantly increased exhaustive treadmill run time. Veillonella utilize lactate as their sole carbon source, which prompted us to perform a shotgun metagenomic analysis in a cohort of elite athletes, finding that every gene in a major pathway metabolizing lactate to propionate is at higher relative abundance postexercise. Us...
Source: Fight Aging! - July 7, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 24th 2019
This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - June 23, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Infection Induced Systemic Inflammation as a Contributing Cause of Alzheimer ' s Disease
The big question regarding Alzheimer's disease has always been why only some people suffer this form of dementia. While being overweight clearly increases the risk of dementia, and it is easy to argue that this is because of the chronic inflammation generated by visceral fat tissue, not every overweight individual progresses to the point of Alzheimer's disease. Some people who are not overweight suffer Alzheimer's disease. The condition starts with rising levels of amyloid-β aggregates forming in the brain, thought to be a progressive process occurring over a decade or more prior to any clinical symptoms, but why does thi...
Source: Fight Aging! - June 20, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs