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10 Questions You Asked Us In The Q & A
It was a great honor to receive hundreds of questions before the live Q&A we recently had. There were in fact so many that I’ve decided I would share some of them here. These questions represent an ample mix of interests, covering a wide range of issues from A.I. to the future of medical education. And worry not if you haven’t gotten your question answered just yet: in the coming weeks we’ll also be writing articles that are based on some of the most intriguing questions. Re-watch the event on YouTube: #1 On The Relationship Of Doctors And Patients What sort of strategies can we use when th...
Source: The Medical Futurist - June 30, 2020 Category: Information Technology Authors: Judit Kuszkó Tags: 3D Printing Artificial Intelligence Digital Health Research E-Patients Future of Medicine Future of Pharma Healthcare Design Robotics Security & Privacy Telemedicine & Smartphones AI Hospital Medical education technology wearab Source Type: blogs

Fight Aging! Newsletter, June 22nd 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - June 21, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Your Smartphone As The Swiss Knife Of Digital Health
7:39 a.m. That’s the time that your smartphone’s sonar deems as optimal for you to wake up today. With its gentle vibration from your bedside table, you pick it up to turn off the smart alarm. As you do so, your phone asks for your permission to use the built-in sensors and camera to run your routine morning scan. It analyzes your voice; evaluates your stress level based on a facial scan; checks your vital signs; and notifies you to take a picture of that mole on your forearm in order to detect any anomalies.  Thereafter, it outputs a comprehensible report with recommendations which you can send over to your ph...
Source: The Medical Futurist - June 16, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence E-Patients Health Sensors & Trackers Telemedicine & Smartphones stress health trackers Huntington's Alzheimer's disease covid19 camera apple health google fit WHO hemoglobin SpO2 Samsung oximetry F Source Type: blogs

Fight Aging! Newsletter, June 8th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - June 7, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reuse of a Small Molecule to Increase Autophagy in the Brain is Trialed for Alzheimer ' s Disease
Today I'll point out an example of drug reuse and autophagy upregulation. The processes of autophagy are responsible for recycling molecular waste and broken cellular structures. Autophagy is upregulated in response to stress placed upon cells, whether by heat, cold, lack of nutrients, a toxic local environment, and so forth. This is beneficial to tissue function, health, and longevity, and thus there is considerable interest in the research community in producing therapies that boost the operation of autophagy. This hasn't made a great deal of progress towards the clinic, but nonetheless in any of the sizable databases of...
Source: Fight Aging! - June 5, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Targeting the Failure of Mitophagy as a Basis for Treating Age-Related Disease
Evidence strongly suggests that the global faltering of mitochondrial function throughout the body with advancing age has a lot to do with a decline in the effectiveness of mitophagy. Mitochondria are the power plants of the cell, a herd of hundreds swarming and replicating like bacteria in every cell to produce the chemical energy store molecule ATP. Mitophagy is the specialized form of autophagy that destroys worn and damaged mitochondria, recycling their component parts. Without it, cells would become overtaken by broken, malfunctioning mitochondria. Mitochondrial dysfunction leads to too little ATP, but also higher lev...
Source: Fight Aging! - June 3, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, June 1st 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 31, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Choosing Between Life and Death During COVID-19: The A.I. Trolley Problem
Suppose you’re the sole witness of a trolley that has gone out of control, hurtling towards 5 people tied to its track, with no way to stop it in time. Good news: there’s a lever you can pull to alter its direction. Bad news: the other track isn’t safe either as it has one person tied to it. What will you do in this situation? Let the trolley continue on its initial course and kill those 5 people on the way or pull the lever to save them at the expense of that other person’s life? Source: https://www.lionsroar.com/ This ethical thought experiment, known as the Trolley Problem, was put forth by Philippa Foot b...
Source: The Medical Futurist - May 14, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Bioethics Future of Medicine Healthcare Policy covid19 Source Type: blogs

Fight Aging! Newsletter, May 11th 2020
In this study, we found that older nematodes have higher ROS levels. Interestingly, after hydrogen treatment, the ROS levels were significantly decreased, and hydrogen could significantly extend the lifespans of the N2, sod-3 and sod-5 mutant strains, by approximately 22.7%, 9.5%, and 8.7%, respectively. In addition, aging is regulated by a variety of pathways, such as the insulin signaling pathway, the rapamycin target signaling pathway, and the caloric restriction pathway. However, our results showed that the lifespans of the daf-2 and daf-16 strains, in which these pathways are upregulated, were not affected afte...
Source: Fight Aging! - May 10, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Our Suffering Parents' Deaths Can Bring Both Sorrow and Relief
Photo credit Neonbrand Dear Carol: Both of my parents were ill for years. Mom, who died two years ago, fought several types of cancer and then developed dementia. Dad, who died three months ago, had a massive stroke right after Mom’s death and his last years were full of physical and emotional pain. My brother and I grieve our parents, but we saw them wear out from health struggles and feel that they are now together in a better place, so there’s quite of bit of relief, as well. Knowing our parents are no longer suffering is part of the relief, but I’m also relieved that I can now spend more time with my husband and ...
Source: Minding Our Elders - April 30, 2020 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Fight Aging! Newsletter, April 27th 2020
In conclusion, our study demonstrated that Nrf2 deficiency promoted the increasing trend of autophagy during aging in skeletal muscle. Nrf2 deficiency and increasing age may cause excessive autophagy in skeletal muscle, which can be a potential mechanism for the development of sarcopenia. To What Degree is Chondrocyte Hypertrophy in Osteoarthritis Due to Cellular Senescence? https://www.fightaging.org/archives/2020/04/to-what-degree-is-chondrocyte-hypertrophy-in-osteoarthritis-due-to-cellular-senescence/ Senescent cells are large. They do not replicate, that function is disabled, but it is as if they go ...
Source: Fight Aging! - April 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, April 20th 2020
In conclusion, elevated brain amyloid was associated with family history and APOE ε4 allele but not with multiple other previously reported risk factors for AD. Elevated amyloid was associated with lower test performance results and increased reports of subtle recent declines in daily cognitive function. These results support the hypothesis that elevated amyloid represents an early stage in the Alzheimer's continuum. Blood Metabolites as a Marker of Frailty https://www.fightaging.org/archives/2020/04/blood-metabolites-as-a-marker-of-frailty/ Frailty in older people is usually diagnosed in a symptomatic ...
Source: Fight Aging! - April 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, April 6th 2020
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - April 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Travis and Ashley rediscover health and slenderness on the Wheat Belly lifestyle
Ashley convinced her husband, Travis, to join her in following the Wheat Belly lifestyle that began with the Wheat Belly 10-Day Grain Detox. Ashley lost 70 pounds, while Travis experienced both weight loss and health/emotional benefits. Travis elaborates: “I feel like I have a new lease on life and I feel better than I have ever felt in my entire life (40 years old). “I started this WOE at 285 lbs on July 21, 2019, so it’s been 8 months and I’m down 65 lbs. It took me a couple months before I finally felt like I had completely detoxed and felt great everyday. It’s a bit overwhelming at first but it all be...
Source: Wheat Belly Blog - March 24, 2020 Category: Cardiology Authors: Dr. Davis Tags: Open Gliadin gluten grain-free Inflammation Weight Loss wheat belly Source Type: blogs

Go figure: A healthy eating approach helps people be healthy
This study was not perfect. You could argue, as these authors do, that the fact that participants chose their preferred diet is a good thing, as it could theoretically improve adherence. However, it also resulted in very different-sized groups to start with. The varying adherence and exercise option choices were adjusted for as well as possible. And the study relied heavily on self-reporting, which is always iffy. Healthy eating patterns have benefits beyond weight loss But we can still learn a great deal here. The Mediterranean approach to eating (which can be easily modified to suit any country or cultural food preferenc...
Source: Harvard Health Blog - March 16, 2020 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Cooking and recipes Diet and Weight Loss Healthy Eating Source Type: blogs