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Total 1091 results found since Jan 2013.

New Technology to Destroy Cancer Cells, Oncotripsy, May Offer Promise
Many of the readers of this blog will be familiar withlithotripsy which involves the use of shock waves to disintegrate stones in the kidneys, bladder, and ureter (see:Lithotripsy). Scientists are now experimenting with the use of ultrasound to selectively kill cancer cells (see:Ultrasound selectively damages cancer cells when tuned to correct frequencies). They have called this type of treatment oncotripsy. Below is an excerpt from the article:A solid mechanics lab at Caltech first developed the theory of oncotripsy, based on the idea that cells are vulnerable to ultrasound at specific frequencies —like how ...
Source: Lab Soft News - January 28, 2020 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Healthcare Delivery Healthcare Innovations Medical Research Source Type: blogs

Astrocyte Senescence Causes Death of Neurons in Cell Culture
With the caveat that the behavior of cells in culture is not necessarily all that relevant to their behavior amidst the full complexities of living tissue, this study is an interesting initial exploration of the ways in which the cellular senescence of supporting cells in the brain might contribute to the progression of neurodegeneration. Senescent cells secrete a potent mix of inflammatory and other signaling; while they serve a useful purpose when present for a short time, not all are successfully destroyed. Their numbers grow with age, and the presence of these errant cells and their signaling is very harmful over the l...
Source: Fight Aging! - January 27, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

‘ Don ’ t Quit Your Day Job ’ : On Working Through a Health Crisis
I had mental health issues in 1991 that caused me to be hospitalized for two weeks, after which I received a diagnosis of bipolar illness. My psychiatrist at the time encouraged me to go back to my full-time teaching job immediately after getting out of the psychiatric ward. This was hard, but I think it was the best thing I could have done in the long run. I remember I was hospitalized in the summer right before the fall semester began. I didn’t have my textbooks to create a syllabus. My brother drove 150 miles over to Pennsylvania to get them. (I was hospitalized in my home state of Ohio.) I remember sitting in the psy...
Source: World of Psychology - January 26, 2020 Category: Psychiatry & Psychology Authors: Laura Yeager Tags: Bipolar Personal Bipolar Disorder Cancer Hospitalization Source Type: blogs

Magnetized Particles Show Live Metabolic Activity of Breast Cancer
Current imaging methods that are used to spot tumors don’t provide much information about the rate of activity of the cells making up the diseased tissues. Breast cancer tumors, for example, are mostly classified into a few categories based on ...
Source: Medgadget - January 24, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Diagnostics Materials Medicine Oncology Radiology Source Type: blogs

Fight Aging! Newsletter, January 6th 2020
Conclusion A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - January 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Look Back at 2019: Progress Towards the Treatment of Aging as a Medical Condition
Conclusion A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - December 31, 2019 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Fight Aging! Newsletter, December 30th 2019
This study presents the effects of berberine (BBR) on the aging process resulting in a promising extension of lifespan in model organisms. BBR extended the replicative lifespan, improved the morphology, and boosted rejuvenation markers of replicative senescence in human fetal lung diploid fibroblasts. BBR also rescued senescent cells with late population doubling (PD). Furthermore, the senescence-associated β-galactosidase (SA-β-gal)-positive cell rates of late PD cells grown in the BBR-containing medium were ~72% lower than those of control cells, and its morphology resembled that of young cells. Mechanistically, BBR im...
Source: Fight Aging! - December 29, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Berberine as an mTOR Inhibitor that Reduces Generation of Senescent Cells and Extends Life Span in Mice
This study presents the effects of berberine (BBR) on the aging process resulting in a promising extension of lifespan in model organisms. BBR extended the replicative lifespan, improved the morphology, and boosted rejuvenation markers of replicative senescence in human fetal lung diploid fibroblasts. BBR also rescued senescent cells with late population doubling (PD). Furthermore, the senescence-associated β-galactosidase (SA-β-gal)-positive cell rates of late PD cells grown in the BBR-containing medium were ~72% lower than those of control cells, and its morphology resembled that of young cells. Mechanistically, BBR im...
Source: Fight Aging! - December 26, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

16 fold higher risk of cancer with peripartum cardiomyopathy
German cancer registry (Robert-Koch-Institute) data has shown a 16 fold risk of cancer in those with peripartum cardiomyopathy [1]. According to the report 21 of 236 patients had cancer, of which 12 had cancer diagnosed before peripartum cardiomyopathy. 11 of them had cardiotoxic chemotherapy. Of these, 17% fully recovered cardiac function compared to 55% of peripartum cardiomyopathy patients without cancer. Of the 10 patients who developed cancer after peripartum cardiomyopathy, 80% had left ventricular ejection fraction of 50% or more after cancer therapy. Authors mention that the high prevalence could be due to geneti...
Source: Cardiophile MD - December 23, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardio Oncology Source Type: blogs

“ Chasing My Cure ” : A Book Review
By CHADI NABHAN, MD, MBA, FACP Have you thought about your own mortality? Who hasn’t, given the frequency of seeing death and grief depicted in the media or through real life encounters with friends, relatives, neighbors, or patients? These incidents trigger uncomfortable and sometimes uneasy thoughts of how we might personally deal with potential illness and disease. The same thoughts are soon displaced by the busyness of living.  Despite dealing with the death of his mother from a brain tumor, we learn David Fajgenbaum was healthy, living life to its fullest, and a future doctor in the making. He may hav...
Source: The Health Care Blog - December 16, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Book Review Chadi Nabhan Chasing My Cure Chasing My Cure book review David Fajgenbaum Mortality Outspoken Oncology Source Type: blogs

Fight Aging! Newsletter, December 16th 2019
This study shows that CA are released from periventricular and subpial regions to the cerebrospinal fluid and are present in the cervical lymph nodes, into which cerebrospinal fluid drains through the meningeal lymphatic system. We also show that CA can be phagocytosed by macrophages. We conclude that CA can act as containers that remove waste products from the brain and may be involved in a mechanism that cleans the brain. Moreover, we postulate that CA may contribute in some autoimmune brain diseases, exporting brain substances that interact with the immune system, and hypothesize that CA may contain brain markers that m...
Source: Fight Aging! - December 15, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Cancer Survivors have Double the Risk of Suffering a Later Stroke
We present a contemporary analysis of risk of fatal stroke among more than 7.5 million cancer patients and report that stroke risk varies as a function of disease site, age, gender, marital status, and time after diagnosis. The risk of stroke among cancer patients is two times that of the general population and rises with longer follow-up time. The relative risk of fatal stroke, versus the general population, is highest in those with cancers of the brain and gastrointestinal tract. The plurality of strokes occurs in patients older than 40 years of age with cancers of the prostate, breast, and colorectum. Patients of any ag...
Source: Fight Aging! - December 9, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Top 10 Technologies We Are Excited About
We cover a lot of news and announcements about digital health technologies to provide context for you. Even within The Medical Futurist team, there are favorite technologies and trends. And we thought it would be time to share the technologies we’re excited about! With advancements in exoskeleton technology, A.I.’s ever-increasing importance in healthcare and technologies like 5G and quantum computing soon going mainstream, there’s much to be excited about! Without further ado, let’s jump in! 1. Quantum Computing: faster, cheaper and safer Late last month, Google claimed “quantum supremacy” and made the c...
Source: The Medical Futurist - December 3, 2019 Category: Information Technology Authors: Prans Tags: Future of Medicine digital health Healthcare technology digital technology Source Type: blogs

How to talk to children about the serious illness of a loved one
It’s an inescapable truth: sometimes hard, bad things happen in life — including that sometimes parents, or other important people in a child’s life, get very sick. It’s natural to want to shield a child from news like this, but that’s not a good idea. Children pick up on more than people realize — and can sometimes imagine things to be even worse than they are. Also, it’s important to help children gain the understanding and skills they need to weather a loved one’s illness, as well as to weather the inevitable difficult times in their future. Talking to a child about serious illness: the first steps Every...
Source: Harvard Health Blog - December 2, 2019 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Adolescent health Children's Health Parenting Relationships Source Type: blogs

The Digital Health Future of Oncology
It’s in the early morning of April 15th, 2030 that when looking at your smart mirror, the latter beeps a warning notification: that new mole on your chin should be checked by your dermatologist. That was to be expected. After all your genetic test revealed that you possess a mutation in the CDKN2A gene. But you also get the recommendation to have your esophagus and stomach checked as your connected smart scale registered a noticeable drop in weight and this mutation also carries an increased risk of gastrointestinal (GI) tract cancer. With such increased awareness and early stage diagnosis methods, will the cancer de...
Source: The Medical Futurist - November 26, 2019 Category: Information Technology Authors: Prans Tags: Future of Medicine Personalized Medicine cancer digital health cancer treatment digital technology oncology cancer research cancer care digital health technologies Source Type: blogs