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Total 3421 results found since Jan 2013.

Self ‐Assembly of Selenium‐Doped Carbon Quantum Dots as Antioxidants for Hepatic Ischemia‐Reperfusion Injury Management
Selenium-doped carbon quantum dots (Se-CQDs)  were self-assembled with distearoyl phosphoethanolamine-PEG2000 (DSPE-PEG2000) and lecithin (LEC) or 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC). The obtained selenium-containing nanoparticles can accumulate in the liver prominently, act as antioxidants to prevent free radicals from destroy ing hepatocytes, and reduce the release of pro-inflammatory cytokines from Kupffer cells, thus exerting an effective therapeutic effect on Hepatic ischemia-reperfusion injury. AbstractHepatic ischemia-reperfusion injury (HIRI) is a critical complication after liver surgery that negat...
Source: Small - April 7, 2023 Category: Nanotechnology Authors: Bing Bai, Shaolong Qi, Kai Yang, Xinyang Yu, Ruijun Jian, Tianfang Zhang, Daming Wang, Hongbo Meng, Yifan Zhao, Yu Xia, Huaping Xu, Guocan Yu, Zuobing Chen Tags: Research Article Source Type: research

The Influence of Liquid Menisci on Nanoparticle Dosimetry in Submerged Cells
Here, the impact of the meniscus, that forms when aqueous cell culture media wets the inner surface of hydrophilic open wells, on nanoparticle dosimetry is addressed in detail. Experiments to determine the influence of different parameters and a mathematical model are presented, which can be adapted for any experimental setups. AbstractUnderstanding the interaction between cells and nanoparticles (NPs) is vital to understand the hazard associated with nanoparticles. This requires quantifying and interpreting dose-response relationships. Experiments with cells cultured in vitro and exposed to particle dispersions mainly rel...
Source: Small - April 6, 2023 Category: Nanotechnology Authors: Christina Glaubitz, Laetitia Haeni, Eva Su šnik, Barbara Rothen‐Rutishauser, Sandor Balog, Alke Petri‐Fink Tags: Research Article Source Type: research

M2 Macrophage Membrane ‐Mediated Biomimetic‐Nanoparticle Carrying COX‐siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation
An M2M@PLGA/COX-siRNA delivery system is  successfully constructed and measured its targeting properties and therapeutic effects on a rat model of flexor digitorum longus tendon injury combined with rotator cuff injury. These findings indicate that the M2M@PLGA delivery system can provide an effective biological strategy for preventing m ultiple tendon adhesions. AbstractTendon adhesion is the most common outcome of tendon or tendon-to-bone healing after injury.  Our group developed a hydrogel-nanoparticle sustained-release system previously to inhibit cyclooxygenases (COXs) expression and consequently prevent tendon a...
Source: Small - April 5, 2023 Category: Nanotechnology Authors: Jie Sun, Fei Ju, Jing Jin, Hao Liang Wang, Zhi Jie Li, Yu Cheng Sun, Qing Zhong Chen, Qian Qian Yang, Jun Tan, You Lang Zhou Tags: Research Article Source Type: research

Microenvironment Engineering to Promote Selective Ammonia Electrosynthesis from Nitrate over a PdCu Hollow Catalyst
An efficient catalyst design strategy is reported to engineer the surface microenvironment of a PdCu hollow catalyst that confines the intermediates and promotes selective NH3 electrosynthesis from nitrate. This catalyst discloses a high NH3 Faradaic efficiency of 87.3% and a remarkable NH3 yield rate of 0.551  mmol h−1 mg−1 at -0.30  V, all of which are better than the counterpart catalysts and the-state-of-the-art catalysts. AbstractThe electrosynthesis of recyclable ammonia (NH3) from nitrate under ambient conditions is of great importance but still full of challenges for practical application. Herein, an efficien...
Source: Small - April 3, 2023 Category: Nanotechnology Authors: Xiaowen Min, Ben Liu Tags: Research Article Source Type: research

Mechanistic Understanding of Protein Corona Formation around Nanoparticles: Old Puzzles and New Insights
A key obstacle in nanomedicine development is the lack of deep mechanistic knowledge regarding nanoparticle interactions in the bioenvironment. Here, recent research aimed at elucidating fundamental properties of the biomolecular adsorption layer (protein corona) around nanoparticles is critically reviewed, and future research is suggested that bears promise to further advance our  understanding of the processes occurring at the nano–bio interface. AbstractAlthough a wide variety of nanoparticles (NPs) have been engineered for use as disease markers or drug delivery agents, the number of nanomedicines in clinical use ha...
Source: Small - April 3, 2023 Category: Nanotechnology Authors: Karin Nienhaus, Gerd Ulrich Nienhaus Tags: Review Source Type: research

Donor:Acceptor Janus Nanoparticle ‐Based Films as Photoactive Layers: Control of Assembly and Impact on Performance of Devices
Donor:acceptor nanoparticles (NPs)  are controllably assembled into close-packed monolayers through the air/water interfacial assembly approach. The device based on close-packed D:A Janus NP-based films exhibits 80% improvement of electron mobility and more balanced charge extraction compared to the conventional core–shell NP-base d device. This work opens a new road for the application of donor:acceptor Janus NPcoatings in optoelectronic applications in the near future. AbstractWater-processable organic semiconductor nanoparticles (NPs) are considered promising materials for the next-generation of optoelectronic applic...
Source: Small - April 3, 2023 Category: Nanotechnology Authors: Yixuan Du, Yuemeng Wang, Volodymyr Shamraienko, Kathrin P öschel, Alla Synytska Tags: Research Article Source Type: research

Modulating Electronic Structure with Copper Doping to Promote the Electrocatalytic Performance of Cobalt Disulfide in Li –O2 Batteries
The incorporation of Cu cation in CoS2 lattice can regulate the electronic structure of CoS2 and modulate the charge distribution between its surface and Li –O species, resulting in a weaker binding strength toward Li–O species and a lower reaction barrier of the rate-determining step, improving the catalytic performance in Li–O2 batteries. AbstractIntroducing heteroatom into catalyst lattice to modulate its intrinsic electronic structure is an efficient strategy to improve the electrocatalytic performance in Li –O2 batteries. Herein, Cu-doped CoS2 (Cu –CoS2) nanoparticles are fabricated by a solvothermal method ...
Source: Small - April 3, 2023 Category: Nanotechnology Authors: Shengqi Ding, Liang Wu, Fang Zhang, Xianxia Yuan Tags: Research Article Source Type: research

Magnetic Heating Amorphous NiFe Hydroxide Nanosheets Encapsulated Ni Nanoparticles@Wood Carbon to Boost Oxygen Evolution Reaction Activity
A magnetic heating strategy is demonstrated to boost the oxygen evolution reaction based on an effective and low-cost carbonized wood electrode decorated with amorphous NiFe hydroxide nanosheets encapsulated Ni nanoparticles. The rising local temperature greatly enhances the adsorption of reaction intermediates for the carbonized wood electrode originating from the magnetic heating effect in an alternating current magnetic field. AbstractThe oxygen evolution reaction (OER) has significant effects on the water-splitting process and rechargeable metal-air batteries; however, the sluggish reaction kinetics caused by the four-...
Source: Small - April 3, 2023 Category: Nanotechnology Authors: Yaoxing Wang, Xueqin Fan, Qiuyu Du, Ying Shang, Xueqi Li, Zhifeng Cao, Xuan Wang, Jian Li, Yanjun Xie, Wentao Gan Tags: Research Article Source Type: research

Interfacial Engineering of CoN/Co3O4 Heterostructured Hollow Nanoparticles Embedded in N ‐Doped Carbon Nanowires as a Bifunctional Oxygen Electrocatalyst for Rechargeable Liquid and Flexible all‐Solid‐State Zn‐Air Batteries
The in situ immobilization of CoN/Co3O4 heterojunction hollow nanoparticles onto porous N-doped carbon nanowires demonstrates excellent bifunctional oxygen electrocatalytic activity and stability with robust cycling stability. AbstractThe design of economical, efficient, and robust bifunctional oxygen electrocatalysts is greatly imperative for the large-scale commercialization of rechargeable Zn-air battery (ZAB) technology. Herein, the neoteric design of an advanced bifunctional electrocatalyst composed of CoN/Co3O4 heterojunction hollow nanoparticles in situ encapsulated in porous N-doped carbon nanowires (denoted as CoN...
Source: Small - April 3, 2023 Category: Nanotechnology Authors: Qixing Zhou, Sike Zhang, Guangyao Zhou, Huan Pang, Mingyi Zhang, Lin Xu, Kang Sun, Yawen Tang, Kai Huang Tags: Research Article Source Type: research

Facile “Synergistic Inner–Outer Activation” Strategy for Nano‐Engineering of Nature‐Skin–Derived Wearable Daytime Radiation Cooling Materials
Herein, a versatile daytime-radiation cooling wearable natural skin (RC-skin) consisting of the collagen micro-nano fibers with the on-demand double-layer radiation cooling structure is nano-engineered through the proposed facile “synergistic inner–outer activation” strategy. Owing to the subtle double-layer structure design, the solar reflectance and the average emissivity of RC-skin are ≈92.7% and ≈95%, respectively. Therefore, the RC-skin has broad-application prospects. AbstractNatural skin –derived products, as traditional wearable materials are widely used in people's daily life due to the products’ exc...
Source: Small - March 31, 2023 Category: Nanotechnology Authors: Long Xie, Xuechuan Wang, Zhongxue Bai, Chao Wei, Manhui Zheng, Ouyang Yue, Xiaoliang Zou, Shuang Liang, Mengchen Huang, Zhenqiang Hou, Xinhua Liu Tags: Research Article Source Type: research

Shaping Sulfur Precursors to Low Dimensional (0D, 1D and 2D) Sulfur Nanomaterials: Synthesis, Characterization, Mechanism, Functionalization, and Applications
This account summarizes the recent progress of low dimensional sulfur nanomaterials including 0D sulfur nanoparticles (SNPs), sulfur nanodots (SNDs), sulfur quantum dots (SQDs), 1D sulfur nanorods (SNRs), and 2D sulfur nanosheets (SNSs), paying attention to the synthetic method, characterization and properties, formation mechanism, surface functionalization, and applications of these sulfur nanomaterials. as well as the prospect and challenges in emerging fields. AbstractLow-dimensional sulfur nanomaterials featuring with 0D sulfur nanoparticles (SNPs), sulfur nanodots (SNDs) and sulfur quantum dots (SQDs), 1D sulfur nanor...
Source: Small - March 29, 2023 Category: Nanotechnology Authors: Wenyi Lu, Zitong Wei, Wenxuan Guo, Chengcheng Yan, Zhaolong Ding, Chunxia Wang, Guoyong Huang, Vincent M. Rotello Tags: Review Source Type: research

Polysaccharide Nanofiber ‐Stabilized Pickering Emulsion Microparticles Induce Pyroptotic Cell Death in Hepatocytes and Kupffer Cells
In this study, the cell death responses of fibroblastic, hepatocyte, and Kupffer cells (KCs) induced by four types of emulsion particles that are stabilized by polysaccharide nanofibers (cellulose or chitin), an inorganic nanoparticle ( β-tricalcium phosphate), or surfactants are compared. Pickering emulsion (PE) microparticles stabilized by polysaccharide nanofibers or inorganic nanoparticles have a droplet size of 1–3 µm, while the surfactant-stabilized emulsion has a diameter of ≈190 nm. Polysaccharide nanofiber-stabiliz ed PEs (PPEs) markedly induce lactate dehydrogenase release in all cell types. Additionally,...
Source: Small - March 29, 2023 Category: Nanotechnology Authors: Qi Li, Mayumi Hatakeyama, Takuya Kitaoka Tags: Research Article Source Type: research

Special Issue: Nanotherapeutics in Women's Health Emerging Nanotechnologies for Triple ‐Negative Breast Cancer Treatment
The recent advances in the nanomedicine field for triple negative breast cancer treatment, from well-established nanoparticles to more advanced exosome-based therapeutic formulations, as well as cutting-edge hybrid systems are herein summarized. It is reinforced the advantages to conventional therapy, including chemotherapy, radiotherapy, and immunotherapy, and the challenges for future clinical applications. The ongoing clinical trials based on nanomedicine are described. AbstractBreast cancer appears as the major cause of cancer-related deaths in women, with more than 2  260 000 cases reported worldwide in 2020, result...
Source: Small - March 29, 2023 Category: Nanotechnology Authors: Sofia Torres Quintas, Ana Canha ‐Borges, Maria José Oliveira, Bruno Sarmento, Flávia Castro Tags: Review Source Type: research

Nanowatt ‐Level Photoactivated Gas Sensor Based on Fully‐Integrated Visible MicroLED and Plasmonic Nanomaterials
This study presents a more advanced monolithic photoactivated gas sensor based on a nanowatt-level, ultra-low-power blue (λpeak = 435 nm) µLED platform (µLP). To promote the blue light absorbance of the sensing material, plasmonic silver (Ag) nanoparticles (NPs) are uniformly coated on porous indium oxide (In2O3) thin films. By the plasmonic effect, Ag NPs absorb the blue light and spontaneously transfer excited hot electrons to the surface of In2O3. Consequently, high external quantum efficiency (EQE, ≈17.3%) and sensor response (ΔR/R0 (%) = 1319%) to 1  ppm NO2 gas can be achieved with a small power consumption o...
Source: Small - March 28, 2023 Category: Nanotechnology Authors: Incheol Cho, Young Chul Sim, Kichul Lee, Minkyu Cho, Jaeho Park, Mingu Kang, Ki Soo Chang, Chan Bae Jeong, Yong ‐Hoon Cho, Inkyu Park Tags: Research Article Source Type: research

Ultrathin Graphdiyne Nanowires with Diameters below 3 nm: Synthesis, Photoelectric Effect, and Enhanced Raman Sensing
The graphdiyne (GDY) ultrathin nanowires with diameters below 3 nm are reported, which exhibit obvious quantum confinement effect, enhanced photoelectric effect, and promising applications in surface-enhanced Raman sensing. AbstractDue to the intrinsic layered structure, graphdiyne (GDY) strongly tends to form 2D materials, therefore, most of the current research are based on GDY 2D structures. Up to now, the synthesis of its ultrathin nanowires with a high aspect ratio has not been reported. Here, the ultrathin GDY nanowires with diameters below 3 nm are reported for the first time by a two-phase interface synthesis metho...
Source: Small - March 28, 2023 Category: Nanotechnology Authors: Linchangqing Yang, Junfang Li, Meng Yin, Qingkong Kong, Guangcheng Xi Tags: Research Article Source Type: research