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Total 3421 results found since Jan 2013.
Biosynthesis of Multifunctional Transformable Peptides for Inducing Tumor Cell Apoptosis
A biosynthesized protein-based material is fabricated by non-pathogenicEscherichia coli (E. coli). The self-assembled nanoparticles of P1 could transform into nanofibers in situ, which could lead to efficient anticancer activity. Furthermore, a spatiotemporally controllable anticancer system is constructed by coating P1-expressingE. coli with cationic conjugated polyelectrolytes to release the peptides in situ under light irradiation. AbstractEngineered nanomaterials hold great promise to improve the specificity of disease treatment. Herein, a fully protein-based material is obtained from nonpathogenicEscherichia coli (E. ...
Source: Small - August 22, 2023 Category: Nanotechnology Authors: Yufei Di,
Qi Shen,
Zhiwen Yang,
Gang Song,
Tiantian Fang,
Yazhou Liu,
Yamei Liu,
Qun Luo,
Fuyi Wang,
Xuehai Yan,
Haotian Bai,
Yiming Huang,
Fengting Lv,
Shu Wang Tags: Research Article Source Type: research
Synthesis of Butterfly ‐Like Shaped Gold Nanomaterial: For the Regulation of Liquid–Liquid Phase‐Separated Biomacromolecule Droplets
The formation/deformation process of liquid –liquid phase separation (LLPS) droplets is modulated using newly synthesized butterfly-shaped gold nanorods (gold nanobutterflies, GNBs). The butterfly shape induced model LLPS droplet formation in high-concentration solutions, and near-infrared laser irradiation on GNBs in the droplets causes on -demand droplet deformation in reversible, irreversible ways. AbstractNanotechnology is a critical tool to manipulate the sophisticated behavior of biological structures and has provided new research fields. Liquid –liquid phase-separated (LLPS) droplets gather attention as basic r...
Source: Small - August 19, 2023 Category: Nanotechnology Authors: Tomohiro Nobeyama,
Koji Tataka,
Megumi Mori,
Tatsuya Murakami,
Yoichi Yamada,
Kentaro Shiraki Tags: Research Article Source Type: research
Exceedingly Small Magnetic Iron Oxide Nanoparticles for T1 ‐Weighted Magnetic Resonance Imaging and Imaging‐Guided Therapy of Tumors
Recent progress in synthesis methods, surface modification,T1-weighted magnetic resonance imaging (MRI) strategies, and MRI-guided cancer therapy utilizing emerging exceedingly small magnetic iron oxide nanoparticles (ES-MIONs) is summarized. AbstractMagnetic iron oxide nanoparticles (MIONs) basedT2-weighted magnetic resonance imaging (MRI) contrast agents (CAs) are liver-specific with good biocompatibility, but have been withdrawn from the market and replaced with Eovist (Gd-EOB-DTPA) due to their inherent limitations (e.g., susceptibility to artifacts, high magnetic moment, dark signals, long processing time ofT2 imaging...
Source: Small - August 19, 2023 Category: Nanotechnology Authors: Jing Yang,
Jie Feng,
Sugeun Yang,
Yikai Xu,
Zheyu Shen Tags: Review Source Type: research
Ag2S Biocompatible Ensembles as Dual OCT Contrast Agents and NIR Ocular Imaging Probes
In recent years, Ag2S nanoparticles have shown great potential in nanomedicine, specifically in areas such as near-infrared (NIR) imaging, photothermal therapy, and photoluminescence nanothermometry. In this work, biocompatible and size-controlled ensembles of Ag2S nanoparticles demonstrate their great dual performance as bright NIR probes and enhancers of the optical coherence tomography signals in ex vivo and in vivo studies. AbstractAg2S nanoparticles (NPs) emerge as a unique system that simultaneously features in vivo near-infrared (NIR) imaging, remote heating, and low toxicity thermal sensing. In this work, their cap...
Source: Small - August 19, 2023 Category: Nanotechnology Authors: Amalia Coro,
Ada Herrero Ruiz,
Mateo Pazo ‐González,
Alonso Sánchez‐Cruz,
Tobias Busch,
Alejandro Hernández Medel,
Erving C. Ximendes,
Dirk H. Ortgies,
Rosalía López‐Méndez,
Ana Espinosa,
Dorleta Jimenez de Aberasturi,
Daniel Jaque, Tags: Research Article Source Type: research
Chirality ‐Dependent Angiogenic Activity of MoS2 Quantum Dots toward Regulatable Tissue Regeneration
Chiral MoS2 QDs are synthesized by usingl/d-penicillamine as functional ligands, which exhibit chirality-dependent effect on the growth, proliferation, migration behaviors of cells.d-MoS2 QDs show enhanced angiogenesis activity and tissue regeneration property thanl-MoS2 QDs, highlighting the great potential of chiral MoS2 QDs in regulatable angiogenesis and regenerative medicine. AbstractDespite great advances in understanding the biological behaviors of chiral materials, the effect of chirality-configured nanoparticles on tissue regeneration-related biological processes remains poorly understood. Herein, the chirality of...
Source: Small - August 17, 2023 Category: Nanotechnology Authors: Kangqiang Liang,
Yumeng Xue,
Bin Zhao,
Mengyao Wen,
Ziqi Xu,
Gleb Sukhorukov,
Lianbing Zhang,
Li Shang Tags: Research Article Source Type: research
Synthesis of Free ‐Standing Pd‐Ni‐P Metallic Glass Nanoparticles with Durable Medium‐Range Ordered Structure for Enhanced Electrocatalytic Properties (Small 33/2023)
Metallic Glass NanoparticlesDuring the synthesis of free-standing metallic glass nanoparticles with laser-evaporated inert-gas condensation, metallic atoms, and distorted short-range-order (SRO) clusters are evaporated to collide and coalesce with each other to form the medium-range ordered (MRO) cluster and nanoparticles, which exhibit durable oxygen reduction reaction (ORR) performance. More details can be found in article number2300721 by He Zhu, Tao Feng, Si Lan, and co-workers.
Source: Small - August 17, 2023 Category: Nanotechnology Authors: Shu Fu,
Guo ‐Xing Chen,
Hu Guo,
Sinan Liu,
Mengyang Yan,
Yu Lou,
Huiqiang Ying,
Zhongzheng Yao,
Yang Ren,
Wei Jiang,
He Zhu,
Horst Hahn,
Tao Feng,
Si Lan Tags: Frontispiece Source Type: research
Synergistic Promotion of the Photocatalytic Preparation of Hydrogen Peroxide (H2O2) from Oxygen by Benzoxazine and Si ─O─Ti Bond
This study involves the preparation of benzoxazine with Si─O bonds via the Mannich reaction, followed by co-hydrolysis to produce photocatalysts containing benzoxazine with Si─O─Ti bonds. In this study, a benzoxazi ne photocatalyst with Si─O─Ti bonds is synthesized and characterized using fourier transform infrared spectroscopy, nuclear magnetic resonance, and X-ray photoelectron spectroscopy. The size and elemental distribution of the nanoparticles are confirmed by transmission electron microscopy and sca nning electron microscopy. The photocatalytic synthesis of H2O2 is tested using the titanium salt detection ...
Source: Small - August 12, 2023 Category: Nanotechnology Authors: Baoliang Liu,
Wenkai Zhang,
Qikun Zhang,
Yintao Guan,
Zaijun Lu Tags: Research Article Source Type: research
Tuning Elastic Properties of Metallic Nanoparticles by Shape Controlling: From Atomistic to Continuous Models
Effect of the shape of nanoparticles on their elastic properties: molecular dynamics (atomistic) and finite elements (continuous) calculations. AbstractUnderstanding and mastering the mechanical properties of metallic nanoparticles is crucial for their use in a wide range of applications. In this context, atomic-scale (molecular dynamics) and continuous (finite elements) calculations is used to investigate in details gold nanoparticles under deformation. By combining these two approaches, it is shown that the elastic properties of such nano-objects are driven by their size but, above all, by their shape. This outcome is ac...
Source: Small - August 11, 2023 Category: Nanotechnology Authors: Matteo Erb ì,
Hakim Amara,
Riccardo Gatti Tags: Research Article Source Type: research
Quantifying the Efficacy of Magnetic Nanoparticles for MRI and Hyperthermia Applications via Machine Learning Methods
A machine learning-based approach is demonstrated for prediction of the specific absorption rate for hyperthermia and r1/r2 relaxivities in magnetic resonance imagining (MRI), with descriptors including parameters of nanoparticles and experimental conditions. DiMag, an open access resource, is developed to guide the synthesis of novel nanosized magnets for MRI and hyperthermia treatment to boost the development of new biomedical agents. AbstractMagnetic nanoparticles are a prospective class of materials for use in biomedicine as agents for magnetic resonance imagining (MRI) and hyperthermia treatment. However, synthesis of...
Source: Small - August 11, 2023 Category: Nanotechnology Authors: Pavel Kim,
Nikita Serov,
Aleksandra Falchevskaya,
Ilia Shabalkin,
Andrei Dmitrenko,
Daniil Kladko,
Vladimir Vinogradov Tags: Research Article Source Type: research
Ratiometric Nanothermometer Based on a Radical Excimer for In Vivo Sensing (Small 32/2023)
Ratiometric NanothermometersOrganic nanoparticles based on persistent TTM radicals containing excimers and isolated molecules exhibit all characteristics of ratiometric nanothermometers showing excellent temperature sensitivity, reversibility, and high colloidal stability. In-vivo experiments made withCaenorhabditis elegans (C. elegans) indicate that they can monitor temperature changes at the (nano)-micron scale from 5 to 40 °C, with very high sensitivity indicating the considerable potential applications in the biological thermometry field. More details can be found in article number2207806 by Jaume Veciana, Imma Ratera, and co-workers.
Source: Small - August 9, 2023 Category: Nanotechnology Authors: Davide Blasi,
Nerea Gonzalez ‐Pato,
Xavier Rodriguez Rodriguez,
Iñigo Diez‐Zabala,
Sumithra Yasaswini Srinivasan,
Núria Camarero,
Oriol Esquivias,
Mònica Roldán,
Judith Guasch,
Anna Laromaine,
Pau Gorostiza,
Jaume Veciana,
Imma Ratera Tags: Inside Back Cover Source Type: research
Bridging a Gap in Thermal Conductivity and Heat Transfer in Hybrid Fibers and Yarns via Polyimide and Silicon Nitride Composites
Yarns based on composite polyimide (PI) nanofibers with silicon nitride (SiN) are used as coatings on resistance wires to assess their thermal conductivity. The highest concentration of SiN (35 wt.%) in PI nanofibers exhibits an increase in the surface temperature analyzed via the scanning thermal microscopy (SThM), thus showing a great promise for effective heat dissipation materials in thermal management applications. AbstractThe pressing issues of the energy crisis and rapid electronics development have sparked a growing interest in the production of highly thermally conductive polymer composites. Due to the challenge...
Source: Small - August 9, 2023 Category: Nanotechnology Authors: Ahmadreza Moradi,
Piotr K. Szewczyk,
Urszula Stachewicz Tags: Research Article Source Type: research
Polyoxometalates@Metal ‐Organic Frameworks Derived Bimetallic Co/Mo2C Nanoparticles Embedded in Carbon Nanotube‐Interwoven Hierarchically Porous Carbon Polyhedron Composite as a High‐Efficiency Electrocatalyst for Al–S Batteries
Polyoxometalates@Metal-Organic frameworks derived bimetallic cobalt clusters with Mo2C nanostructures embedded in carbon nanotubes interlaced layered porous carbon (Co/Mo2C@NCNHP) not only can effectively promote the electron transport within the cathode and confine the shuttle effect of aluminum polysulfides (AlPSs) by physical confinement and chemical adsorption, but also can catalyze the reversible kinetics of aluminum polysulfide conversion in Al –S battery (ASB). AbstractAl –S battery (ASB) is a promising energy storage device, notable for its safety, crustal abundance, and high theoretical energy density. However...
Source: Small - August 4, 2023 Category: Nanotechnology Authors: Qiuping Zhou,
Xuecheng Zhang,
Yuchao Wu,
Xinyuan Jiang,
Tangsuo Li,
Ming Chen,
Lubin Ni,
Guowang Diao Tags: Research Article Source Type: research
Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta
Lipid nanoparticle (LNP)-mediated delivery of messenger RNA (mRNA) is a promising approach for treating placental disorders. Here, iterative libraries of LNPs with varied excipient molar ratios are screened in vitro for enhanced mRNA LNP delivery to placental cells. The top LNP formulation identified during in vitro screening mediates in vivo mRNA delivery to placental trophoblasts, endothelial, cells and immune cells. AbstractDuring healthy pregnancy, the placenta develops to allow for exchange of nutrients and oxygen between the mother and the fetus. However, placental dysregulation can lead to several pregnancy disord...
Source: Small - August 4, 2023 Category: Nanotechnology Authors: Hannah C. Safford,
Kelsey L. Swingle,
Hannah C. Geisler,
Alex G. Hamilton,
Ajay S. Thatte,
Aditi A. Ghalsasi,
Margaret M. Billingsley,
Mohamad ‐Gabriel Alameh,
Drew Weissman,
Michael J. Mitchell Tags: Research Article Source Type: research
Virus ‐Like Magnetic Heterostructure: an Outstanding Metal‐Complex Active Platform Enables High‐Efficiency Separation and Catalysis
Here, the study describes an easy-to-execute strategy to fabricate magnetic heterostructure as a multifunctional delivery system. first-row transition metal copper and nitroso/amino ligand as modules to assemble around Fe3O4 magnetic nanoparticles by excessed mild stimuli and fabricate the magnetic heterostructure materials is utilized. The Fe3O4@ TACN NPs can effectively isolate Cyt-c from complex biological samples (pork heart). Importantly, the Fe3O4@ TACN NPs coordinated with heme-structure, induced methionine 80 disassociates from heme prosthetic group, and contributed to peroxidase-like activities increasing. Abstrac...
Source: Small - August 4, 2023 Category: Nanotechnology Authors: Zhiyong Guo,
Chen Zhang,
Tongxu He,
Huaiyu Xiao,
Jingwen Jin,
Qiuhong Yao,
Tingxiu Ye,
Xi Chen Tags: Research Article Source Type: research
Pt ‐Loaded Nb─W Metal Composite Oxide for Selective Cleavage of Secondary C─O Bonds
A uniform Pt/Nb14W3O44 catalyst with crystallographic shear structure is developed for the extremely efficient and selective hydrogenolysis of glycerol to 1,3-propanedio with excellent stability, reaching an exceptional 75.2% yield of 1,3-propanediol. Strong interaction between Nb14W3O44 and Pt can coordinate the precise adsorption and activation of the secondary C ─O bond, simultaneously triggering subsequent hydrogenation. AbstractSelective hydrogenolysis of glycerol to 1,3-propanediol (1,3-PDO) is recognized as one of the most promising reactions for the valorization of biomass. Precise activation of C ─O bonds of...
Source: Small - August 3, 2023 Category: Nanotechnology Authors: Jinghu Chen,
Qineng Xia,
Yong Guo,
Yangang Wang,
Xi Li,
Mingming Wang,
Jieshan Qiu,
Yanqin Wang,
Maria Veronica Sofianos,
Shaomin Liu Tags: Research Article Source Type: research
