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Total 3421 results found since Jan 2013.
Nanoghosts: Harnessing Mesenchymal Stem Cell Membrane for Construction of Drug Delivery Platforms Via Optimized Biomimetics
This review describes the advantages and current applications of cell membrane carried nanoparticles as drug delivery platform, or so called “nanoghost.” Specifically, this work states several beneficial characteristics that made mesenchymal stem cells promising for nanoghost development, and discussed the possibility to further optimize biomimetic systems for enhanced drug delivery. AbstractMesenchymal stem cells (MSCs) are becoming hotspots for application in disease therapies recently, combining with biomaterials and drug delivery system. A major advantage of MSCs applied in drug delivery system is that these cells ...
Source: Small - September 1, 2023 Category: Nanotechnology Authors: Yuan Xiao,
Ren ‐He Xu,
Yunlu Dai Tags: Review Source Type: research
Dual Heterojunctions and Nanobowl Morphology Engineered BiVO4 Photoanodes for Enhanced Solar Water Splitting
A unique BiVO4 (BVO) nanobowl (NB) heterojunction photoanode, which consists of [001]-oriented BiOCl underlayer and BVO nanobowls containing embedded BiOCl nanocrystals, is fabricated by nanosphere lithography followed by in situ transformation. It exhibits attractive PEC performance toward water oxidation with an excellent bulk charge separation efficiency of 95.5%, and a remarkable photocurrent density of 3.38 mA cm−2 at 1.23 V versus reversible hydrogen electrode. AbstractPhotoelectrochemical (PEC) water splitting represents an attractive strategy to realize the conversion from solar energy to hydrogen energy, but s...
Source: Small - September 1, 2023 Category: Nanotechnology Authors: Kexin Ren,
Jiayi Zhou,
Zihao Wu,
Qi Sun,
Limin Qi Tags: Research Article Source Type: research
A Purposefully Designed pH/GSH ‐Responsive MnFe‐Based Metal‐Organic Frameworks as Cascade Nanoreactor for Enhanced Chemo‐Chemodynamic‐Starvation Synergistic Therapy
A pH and glutathione dual-responsive cascade nanoreactor is designed and synthesized by adjusting the ratio of Mn/Fe coordinated with syringic acid for targeted delivery of cisplatin prodrugs and biomimetic glucose oxidase to enhance synergistic therapy. The results demonstrate that the full-featured nanoreactor exhib its intensive chemodynamic therapy effect due to the optimal Mn/Fe ratio to synergistic with chemo-starvation therapy for anticancer. AbstractMetal-organic frameworks (MOFs) have emerged as promising novel therapeutics for treating malignancies due to their tunable porosity, biocompatibility, and modularity...
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Wei Jun Chen,
Dhanu Gupta,
Meiyang Yang,
Fuwei Yang,
Ning Feng,
Junling Song,
Matthew J. A. Wood,
Lipeng Qiu,
Jinghua Chen Tags: Research Article Source Type: research
Synergistic Enhancement of Photocatalytic CO2 Reduction by Built ‐in Electric Field/Piezoelectric Effect and Surface Plasmon Resonance via PVDF/CdS/Ag Heterostructure
In this study, polyvinylidene fluoride (PVDF) ferroelectric/piezoelectric nanofiber membranes are prepared by electrospinning. Cadmium sulfide (CdS) nanosheets are assembled in situ on the surface of PVDF based on coordination between F− and Cd2+, and then Ag nanoparticles are deposited on CdS. Because of the synergistic effect between localized surface plasmon resonance of Ag nanoparticles and the built-in electric field of PVDF, the CO2 photocatalytic reduction efficiency using PVDF/CdS/Ag under visible light irradiation is significantly higher than that of any combination of CdS, CdS/Ag, or PVDF/CdS. Under micro-vibra...
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Zijun Wei,
Tuo Ji,
Xuemei Zhou,
Jiawei Guo,
Xin Yu,
Hong Liu,
Jingang Wang Tags: Research Article Source Type: research
Densification Induced Decoupling of Electrical and Thermal Properties in Free ‐Standing MWCNT Films for Ultrahigh p‐ and n‐Type Power Factors and Enhanced ZT
Densifying multi-walled carbon nanotube (MWCNT) films would increase their electrical conductivity dramatically up to over 10 000 S cm−1 with maintained high Seebeck coefficients>60 µV K−1, thus leading to ultrahigh power factors of 7.25 and 4.34 mW m−1 K−2 for p- and n-type MWCNT films, respectively, which are the top values for organic flexible thermoelectric films. AbstractGenerating sufficient power from waste heat is one of the most important things for thermoelectric (TE) techniques in numerous practical applications. The output power density of an organic thermoelectric generator (OTEG) is pro...
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Kuncai Li,
Xu Sun,
Yizhuo Wang,
Jing Wang,
Xu Dai,
Yanqiu Yao,
Bin Chen,
Daotong Chong,
Junjie Yan,
Hong Wang Tags: Research Article Source Type: research
Multivalent Targeting of the Asialoglycoprotein Receptor by Virus ‐Like Particles
Delivery of drugs to particular cell types in the liver is a useful goal. Heptatocytes are typically targeted using molecules that bind to the asialoglycoprotein receptor. This paper describes the construction of protein nanoparticles with ultra-high affinity for cells bearing this receptor, while showing that uptake by other liver cells is difficult to overcome if hepatocyte-specific delivery is desired. AbstractThe asialoglycoprotein receptor (ASGPR) is expressed in high density on hepatocytes. Multivalent variants of galactosyl carbohydrates bind ASGPR with high affinity, enabling hepatic delivery of ligand-bound cargo....
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Robert Hincapie,
Sonia Bhattacharya,
Michael M. Baksh,
Carlos A. Sanhueza,
Elisa Schrader Echeverri,
Hyejin Kim,
Kalina Paunovska,
Ananda R. Podilapu,
Minghao Xu,
James E. Dahlman,
M. G. Finn Tags: Research Article Source Type: research
Current Progress of Mo ‐Based Metal Organic Frameworks Derived Electrocatalysts for Hydrogen Evolution Reaction
The progress of Mo-based metal organic frameworks derived electrocatalysts for hydrogen evolution reaction is summarized including Mo2C, MoO2, MoP, MoS2, and MoNx, and the commonly used strategies to improve catalytic performance such as heteroatoms doping, constructing heterogeneous structure, and composited with noble metal are discussed. AbstractAs an important half-reaction for electrochemical water splitting, electrocatalytic hydrogen evolution reaction suffers from sluggish kinetics, and it is still urgent to search high efficiency non-platinum-based electrocatalysts. Mo-based catalysts such as Mo2C, MoO2, MoP, MoS2,...
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Siru Chen,
Junlong Xu,
Junyan Chen,
Yingying Yao,
Fang Wang Tags: Review Source Type: research
In Situ Transmission Electron Microscopy to Study the Location and Distribution Effect of Pt on the Reduction of Co3O4 –SiO2
This study for the first time unravels the effects of Pt location and distribution on the reduction of Co3O4 nanoparticles, and helps to design cobalt-based catalysts with efficient use of Pt as a reduction promoter.
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Min Tang,
Petra E. Jongh,
Krijn P. de Jong Tags: Research Article Source Type: research
Next ‐Generation Nanopore Sensors Based on Conductive Pulse Sensing for Enhanced Detection of Nanoparticles
A new paradigm in nanopore research that takes advantage of a polymer electrolyte system and a conductive pulse sensing approach is presented. This system enables the analytical characterization of heterogeneous nanoparticle mixtures at low ionic strength. The wide applicability of the method is demonstrated by characterizing nanospheres of varied sizes, plasmonic nanostars, and protein-based spherical nucleic acids. AbstractNanopore sensing has been successfully used to characterize biological molecules with single-molecule resolution based on the resistive pulse sensing approach. However, its use in nanoparticle characte...
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Samuel Confederat,
Seungheon Lee,
Der Vang,
Dimitrios Soulias,
Fabio Marcuccio,
Timotheus I. Peace,
Martin Andrew Edwards,
Pietro Strobbia,
Devleena Samanta,
Christoph W älti,
Paolo Actis Tags: Research Article Source Type: research
In Situ Intrinsic Self ‐Healing of Low Toxic Cs2ZnX4 (X = Cl, Br) Metal Halide Nanoparticles
This study reveals the self-healing ability of Cs2ZnX4 (X = Cl, Br) metal halide nanoparticles (NPs). When subjected to local heating by electron beam irradiation, the NPs form nanoshells (NSs) that subsequently heal back to their original state within minutes, restoring their original phase and structure. AbstractThis study reports on the intrinsic and fast self-healing ability of all inorganic, low-toxic Cs2ZnX4 (X = Cl, Br) metal halide nanoparticles (NPs) when subjected to local heating by electron beam irradiation in high-resolution transmission electron microscopy (HR-TEM). The local heating induces the creatio...
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Ben Aizenshtein,
Lioz Etgar Tags: Research Article Source Type: research
An Amiable Design of Cobalt Single Atoms as the Active Sites for Oxygen Evolution Reaction in Desalinated Seawater
The waste orange peel can function as a green solvent and generate porous carbon (PC) templates with defective sites, which will stimulate the distribution, and growth of cobalt single atoms as well as cobalt oxide ultrasmall nanoparticles throughout the surface. The developed Co SA-Co3O4@PC illustrates excellent oxygen evolution reaction (OER) and stability over 100h in alkaline desalinated seawater. AbstractGreen fuel from water splitting is hardcore for future generations, and the limited source of fresh water (<1%) is a bottleneck. Seawater cannot be used directly as a feedstock in current electrolyzer techniques. U...
Source: Small - August 31, 2023 Category: Nanotechnology Authors: Sada Venkateswarlu,
Muhammad Umer,
Younghu Son,
Saravanan Govindaraju,
Gayathri Chellasamy,
Atanu Panda,
Juseong Park,
Sohaib Umer,
Jeonghyeon Kim,
Sang ‐Il Choi,
Kyusik Yun,
Minyoung Yoon,
Geunsik Lee,
Myung Jong Kim Tags: Research Article Source Type: research
Spontaneous Chiral Symmetry Breaking and Lane Formation in Ferromagnetic Ferrofluids
Spontaneous chiral symmetry breaking is observed when exposing a ferromagnetic ferrofluid to an oscillating magnetic field. For specific field parameters, a periodic striped structure of elongated magnetic domains appears. Between individual domains, a flow of several µm s−1 is detected, with the fluid in adjacent lanes moving in alternating directions despite the applied magnetic field being spatially uniform. AbstractFerromagnetic ferrofluids are synthetic materials consisting of magnetic nanoplatelets dispersed in an isotropic fluid. Their main characteristics are the formation of stable magnetic domains and the pre...
Source: Small - August 30, 2023 Category: Nanotechnology Authors: Mojca Vilfan,
Borut Lampret, Žiga Gregorin,
Luka Cmok,
Andrej Vilfan,
Jürgen Klepp,
Joachim Kohlbrecher,
Patricija Hribar Boštjančič,
Darja Lisjak,
Alenka Mertelj Tags: Research Article Source Type: research
Dual ‐Wave Acoustofluidic Centrifuge for Ultrafast Concentration of Nanoparticles and Extracellular Vesicles (Small 35/2023)
Surface Acoustic WavesThe acoustofluidic concentration of extracellular vesicles (ACEV) technique leverages the power of dual acoustic waves, creating a single vortex stream within a droplet that serves to concentrate extracellular vesicles effectively. This state-of-the-art method, with immense potential for advancing cancer research, employs a carefully positioned thin-film circuit board on a piezoelectric substrate. These components are designed to generate the optimal acoustic field, enabling the efficient and precise concentration of these vital nanostructures, which play significant roles in cancer progression and in...
Source: Small - August 29, 2023 Category: Nanotechnology Authors: Povilas Dum čius,
Roman Mikhaylov,
Xiaoyan Zhang,
Matthew Bareford,
Mercedes Stringer,
Rachel Errington,
Chao Sun,
Esperanza Gonzalez,
Tomaš Krukovski,
Juan M Falcon‐Perez,
Dongfang Liang,
Yong‐Qing Fu,
Aled Clayton,
Xin Yang Tags: Inside Front Cover Source Type: research
Ultrasensitive Terahertz Biodetection Enabled by Quasi ‐BIC‐Based Metasensors (Small 35/2023)
Ultrasensitive Terahertz BiodetectionIn article number2301165, Chao Chang, Xiaohui Du, and co-workers demonstrate a chip-based portable ultra-sensitive THz metasensor by exploring quasi-bound states in the continuum and report its capability for sensing low-concentration analytes. The designed metasensor is made of the designed split-ring resonator metasurface combining functionalized gold nanoparticles conjugated with the specific antibody.
Source: Small - August 29, 2023 Category: Nanotechnology Authors: Ride Wang,
Lei Xu,
Lujun Huang,
Xiaobao Zhang,
Hao Ruan,
Xiao Yang,
Jing Lou,
Chao Chang,
Xiaohui Du Tags: Frontispiece Source Type: research
Emergency Treatment and Photoacoustic Assessment of Spinal Cord Injury Using Reversible Dual ‐Signal Transform‐Based Selenium Antioxidant (Small 35/2023)
Spinal Cord InjuriesIn article number2207888, Xianjin Du, Jian Zhang, Hongsheng Lin, Yuhui Liao, and co-workers design an emergency treatment and photoacoustic severity assessment (ETPSA) strategy for spinal cord injury (SCI) based on the selenium (Se) matrix antioxidant system Se@BDP-DOH nanoparticles, which can real-time evaluate the severity of SCI using photoacoustic signals and simultaneously effectively inhibit oxidative stress-induced damage in neuron cells to reconstruct the redox microenvironment, accompanying the increasing branch and extension of nerves.
Source: Small - August 29, 2023 Category: Nanotechnology Authors: Zhisheng Ji,
Judun Zheng,
Yanming Ma,
Hongyi Lei,
Weiqiang Lin,
Jialin Huang,
Hua Yang,
Guowei Zhang,
Bin Li,
Bowen Shu,
Xianjin Du,
Jian Zhang,
Hongsheng Lin,
Yuhui Liao Tags: Inside Back Cover Source Type: research
