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Total 3421 results found since Jan 2013.
Nonferrous Ferroptosis Inducer Manganese Molybdate Nanoparticles to Enhance Tumor Immunotherapy
Manganese molybdate nanoparticles (MnMoOx NPs) depleted the highly expressed glutathione (GSH) in tumors and inhibited glutathione peroxidase 4 (GPX4) expression, thus triggering ferroptosis, inducing immune cell death (ICD), further releasing damage-associated molecular patterns (DAMPs), and enhancing tumor immunotherapy. AbstractTumor immunotherapy is an important tool in oncology treatment. However, only a small percentage of patients have an effective immune response to tumor immunotherapy due to the poor infiltration of pro-inflammatory immune cells in immune “cold” tumors and an immunosuppressive network in the t...
Source: Small - July 8, 2023 Category: Nanotechnology Authors: Huali Lei,
Quguang Li,
Zifan Pei,
Lin Liu,
Nailin Yang,
Liang Cheng Tags: Research Article Source Type: research
A Trojan ‐Horse‐Like Biomimetic Nano‐NK to Elicit an Immunostimulatory Tumor Microenvironment for Enhanced GBM Chemo‐Immunotherapy
This study may offer valuable insights for developing biomimetic nanoparticles to potentiate GBM chemo- and immuno-therapies in the future.
Source: Small - July 8, 2023 Category: Nanotechnology Authors: Long Zhang,
Yining Zhang,
Xu Wang,
Yi Zhou,
Ji Qi,
Linbo Gu,
Qiu Zhao,
Rutong Yu,
Xiuping Zhou Tags: Research Article Source Type: research
Nanoparticles Mediated the Diagnosis and Therapy of Glioblastoma: Bypass or Cross the Blood –Brain Barrier
The vital step in the diagnosis and treatment of glioblastoma is to overcome blood –brain barrier (BBB). The pathways are summarized to access the brain from two aspects, including bypassing and crossing the BBB. Then the recent advances in nanomaterial-mediated pathways crossing the BBB in glioblastoma are amplified. Finally, the obstacles and the application prospects of nanot echnology in glioblastoma are discussed. AbstractGlioblastoma is one of the most aggressive central nervous system malignancies with high morbidity and mortality. Current clinical approaches, including surgical resection, radiotherapy, and chemot...
Source: Small - July 7, 2023 Category: Nanotechnology Authors: Xiaowei Song,
Haisheng Qian,
Yongqiang Yu Tags: Review Source Type: research
Synergistic Effect of Electron Scattering and Space Charge Transfer Enabled Unprecedented Room Temperature NO2 Sensing Response of SnO2
To develop the room temperature NO2 sensor with high response, fast recovery, and exceptional selectivity, porous SnO2 nanoparticles with rich oxygen vacancies are synthesized via acetylacetone-assisted solvent evaporation followed by N2 and air calcinations. The fascinating sensing properties are mainly attributed to the unique synergistic effect of electron scattering and space charge transfer. AbstractMetal oxide gas sensors have long faced the challenge of low response and poor selectivity, especially at room temperature (RT). Herein, a synergistic effect of electron scattering and space charge transfer is proposed to ...
Source: Small - July 5, 2023 Category: Nanotechnology Authors: Yajie Zhang,
Yadong Jiang,
Zhen Yuan,
Bohao Liu,
Qiuni Zhao,
Qi Huang,
Ziteng Li,
Wen Zeng,
Zaihua Duan,
Huiling Tai Tags: Research Article Source Type: research
Design and Synthesis of Cabazitaxel Loaded Core ‐Shell Mesoporous Silica Nanoparticles with Different Morphologies for Prostate Cancer Therapy
Various morphologically different core-shell mesoporous silica nanoparticles (CSMS) are synthesised using a dual surfactant approach with their formation mechanism, and the effect of the morphology of cabazitaxel-loaded CSMS in cellular uptake is studied using prostate cancer cells. AbstractIn this work, the synthesis of core-shell ordered mesoporous silica nanoparticles (CSMS) with tunable particle size and shape through a dual surfactant-assisted approach is demonstrated. By varying the synthesis conditions, including the type of the solvent and the concentration of the surfactant, monodispersed and ordered mesoporous si...
Source: Small - June 30, 2023 Category: Nanotechnology Authors: Shan Mohanan,
CI Sathish,
Kavitha Ramadass,
Mingtao Liang,
Ajayan Vinu Tags: Research Article Source Type: research
Unveiling Interfacial Effects for Efficient and Stable Hydrogen Evolution Reaction on Ruthenium Nanoparticles ‐Embedded Pentlandite Composites
In this study, ruthenium nanoparticles (Ru NPs) are in situ grown on Fe5Ni4S8 support (Ru/FNS) by replacement growth strategy. An efficient Ru/FNS electrocatalyst with enhanced interfacial effect is then developed and successfully applied for pH-universal hydrogen evolution reaction (HER). The Fe vacancies formed by FNS during the electrochemical process are found to be conducive to the introduction and firm anchoring of Ru atoms. Compared to Pt atoms, Ru atoms get easily aggregated and then grow rapidly to form NPs. This induces more bonding between Ru NPs and FNS, preventing the fall-off of Ru NPs and maintaining the str...
Source: Small - June 30, 2023 Category: Nanotechnology Authors: Chenxu Zhang,
Yanan Cui,
Chao Jiang,
Yaxin Li,
Zeshuo Meng,
Chong Wang,
Zhengyan Du,
Shansheng Yu,
Hongwei Tian,
Weitao Zheng Tags: Research Article Source Type: research
An Emerging Family of Piezocatalysts: 2D Piezoelectric Materials
2D piezoelectric materials constitute a promising alternative for piezocatalysis due to their inherent advantages, such as high flexibility, large surface area, and abundant active sites. In this review, the state-of-the-art research progresses on 2D piezoelectric materials and their applications in piezocatalysis are summarized. The overall goal is to inspire and accelerate the practical deployment of 2D piezoelectric materials for piezocatalytic applications. AbstractPiezocatalysis is an emerging technique that holds great promise for the conversion of ubiquitous mechanical energy into electrochemical energy through piez...
Source: Small - June 30, 2023 Category: Nanotechnology Authors: Cheng ‐Chao Jin,
Dai‐Ming Liu,
Ling‐Xia Zhang Tags: Review Source Type: research
Confinement Effects on the Structure of Entropy ‐Induced Supercrystals
Gold triangles (AuNTs) and silver nanorods (AgNRs) are assembled by depletion-induced self-assembly. Structural analysis shows that the AuNTs and AgNRs form 3D and 2D hexagonal lattices in bulk, respectively. The colloidal crystals are also imaged by in situ Liquid-Cell Transmission Electron Microscopy. Under confinement, the affinity of the nanoparticles for the liquid cell windows leads to SCs with a lower dimensionality than their bulk counterparts. AbstractDepletion-induced self-assembly is routinely used to separate plasmonic nanoparticles (NPs) of different shapes, but less often for its ability to create supercrysta...
Source: Small - June 30, 2023 Category: Nanotechnology Authors: Claire Goldmann,
Wajdi Cha âbani,
Claire Hotton,
Marianne Impéror‐Clerc,
Adrien Moncomble,
Doru Constantin,
Damien Alloyeau,
Cyrille Hamon Tags: Research Article Source Type: research
Engineered Collaborative Size Regulation and Shape Engineering of Tremella ‐Like Au‐MnOx for Highly Sensitive Bimodal‐Type Lateral Flow Immunoassays
To circumvent the issue of difficulty in distinguishing color changes due to subtle variations in target concentrations and facilitate high-sensitivity analysis of lateral flow immunoassays (LFIAs), engineered collaborative size regulationand shape engineering supported black tremella-like gold-manganese oxide (Au-MnOx) nanoparticles with precise MnCl2 regulation are prepared for bimodal-type LFIA via a facile one-pot redox reaction in an alkaline environment. AbstractEngineered collaborative size regulation and shape engineering of multi-functional nanomaterials (NPs) offer extraordinary opportunities for improving the an...
Source: Small - June 29, 2023 Category: Nanotechnology Authors: Sijie Liu,
Yangjun Liao,
Yinuo Zhang,
Rui Shu,
Mingrui Zhang,
Xing Luo,
Chenyang Sun,
Leina Dou,
Linpin Luo,
Jing Sun,
Daohong Zhang,
Lintao Zeng,
Jianlong Wang Tags: Research Article Source Type: research
A Novel Z ‐Scheme Heterostructured Bi2S3/Cu‐TCPP Nanocomposite with Synergistically Enhanced Therapeutics against Bacterial Biofilm Infections in Periodontitis
The designed Z-scheme heterostructure Bi2S3/Cu-TCPP greatly improves antibacterial photodynamic therapy, and the photothermal therapy of Bi2S3 NPs promotes the release of Cu2+, which can accelerate the consumption of glutathione in pathogenic bacteria and simultaneously produce the effect of chemodynamic therapy. This synergistic effect endows Bi2S3/Cu-TCPP nanocomposites with excellent bactericidal ability, and also significantly alleviates periodontal inflammation in animal models. AbstractPorphyrin-based antibacterial photodynamic therapy (aPDT) has found widespread applications in treating periodontitis. However, its c...
Source: Small - June 28, 2023 Category: Nanotechnology Authors: Qingchao Kong,
Manlin Qi,
Wen Li,
Yujia Shi,
Jing Su,
Shimeng Xiao,
Jiao Sun,
Xue Bai,
Biao Dong,
Lin Wang Tags: Research Article Source Type: research
Facile Synthesis of Self ‐Targeted Zn2+‐Gallic acid Nanoflowers for Specific Adhesion and Elimination of Gram‐Positive Bacteria
For the first time, Gram –positive bacteria adhesive Zn2+-gallic acid nanoflowers (ZGNFs) are synthesized by a facile hydrothermal method without additional stabilizing agents. High bactericidal effect of ZGNFs toward various Gram-positive bacteria is observed in multiple environments. In a MRSA-induced keratitis model, ZGNFs exhibit long-term retention in the infected corneal site and prominent MRSA elimination efficacy. AbstractTransition metal ions are served as disinfectant thousand years ago. However, the in vivo antibacterial application of metal ions is strongly restricted due to its high affinity with proteins an...
Source: Small - June 28, 2023 Category: Nanotechnology Authors: Yue Huang,
Yongcheng Chen,
Zhouyu Lu,
Bo Yu,
Lingyun Zou,
Xiaohui Song,
Haijie Han,
Qiao Jin,
Jian Ji Tags: Research Article Source Type: research
Modulating Ionic Transport and Interface Chemistry via Surface ‐Modified Silica Carrier in Nano Colloid Electrolyte for Stable Cycling of Li‐Metal Batteries
CA-SiO2 nano-carrier simultaneously modulates Li+ solvation structure and solid –electrolyte interphase (SEI) chemistry by capturing anions and additives while approaching toward LMAs. C-SCE treated with citric acid, which can capture abundant anions and additives, guides the active participation of fluoroethylene carbonate (FEC) in the Li+ solvation shell, enhancing thetLi+. C-SCE reinforces SEI via co-implantation of SiO2 and fluorinated components, thereby suppressing Li dendrite formation. AbstractTailoring the Li+ microenvironment is crucial for achieving fast ionic transfer and a mechanically reinforced solid –el...
Source: Small - June 28, 2023 Category: Nanotechnology Authors: Minhong Lim,
Hyeongguk An,
Jiyeon Seo,
Mingyu Lee,
Hyuntae Lee,
Hyeokjin Kwon,
Hee ‐Tak Kim,
Daniel Esken,
Ryo Takata,
Hyun A Song,
Hongkyung Lee Tags: Research Article Source Type: research
Insights into Electrode Architectures and Lithium ‐Ion Transport in Polycrystalline V2O5 Cathodes of Solid‐State Batteries
Li-free cathode, V2O5, is engineered to be used for polymer-based solid-state batteries (SSBs) and realizes high energy density, due to the heterogeneous transmission channel and suitable operational voltage. Using nanoindentation/scratch testing and 3D roughness reconstruction, microstructural characteristics of the solid electrolytes are intuitively observed. Rapid Li-ion diffusion in SSB s is explicitly studied through dynamically qualitative and quantitative measurement. AbstractPolymer-based solid-state batteries (SSBs) have received increasing attentions due to the absence of interfacial problems in sulfide/oxide-t...
Source: Small - June 28, 2023 Category: Nanotechnology Authors: Zhenjiang Yu,
Hongmei Shan,
Yunlei Zhong,
Guo Hong,
Kwan San Hui,
Xia Zhang,
Kwun Nam Hui Tags: Research Article Source Type: research
Synthesis of Bitten Gold Nanoparticles with Single ‐Particle Chiroptical Responses (Small 26/2023)
Bitten Gold NanoparticlesUnprecedented bitten gold nanoparticles are produced through a combination of seed-mediated growth and chemical etching. Each nanoparticle has an irregular nanocavity on it. The presence of an irregular nanocavity causes the bitten gold nanoparticles to exhibit strong single-particle chiroptical responses. More details can be found in article number2301476 by Jianfang Wang and co-workers.
Source: Small - June 27, 2023 Category: Nanotechnology Authors: Han Zhang,
Yang Chen,
Ka Kit Chui,
Jiapeng Zheng,
Yicong Ma,
Danjun Liu,
Zhifeng Huang,
Dangyuan Lei,
Jianfang Wang Tags: Cover Picture Source Type: research
Thermally Derived Hierarchical Nanoplates for Electromagnetic Protection and Waste Energy Recovery Device
Novel 2D carbon-based nanoplates with uniformly embedded Co nanoparticles are prepared, with highly tunable electromagnetic properties and excellent electrochemical performance. Based on this, a creative energy conversion device is constructed, which can convert harmful EM radiation to useful electric energy for recycling. This work offers a new horizon for the development of advanced electromagnetic materials and functional devices. AbstractWith the advent of intelligent society and the popularity of electronic equipment, the protection and treatment of electromagnetic (EM) radiation have become hot research topics all ov...
Source: Small - June 27, 2023 Category: Nanotechnology Authors: Meng ‐Qi Wang,
Jin‐Cheng Shu,
Xiao Wan,
Wen‐Qiang Cao,
Mao‐Sheng Cao Tags: Research Article Source Type: research
