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Total 2868 results found since Jan 2013.

Molecules, Vol. 28, Pages 3881: Bismuth-Decorated Honeycomb-like Carbon Nanofibers: An Active Electrocatalyst for the Construction of a Sensitive Nitrite Sensor
an Zheng Yong Guo The existence of carcinogenic nitrites in food and the natural environment has attracted much attention. Therefore, it is still urgent and necessary to develop nitrite sensors with higher sensitivity and selectivity and expand their applications in daily life to protect human health and environmental safety. Herein, one-dimensional honeycomb-like carbon nanofibers (HCNFs) were synthesized with electrospun technology, and their specific structure enabled controlled growth and highly dispersed bismuth nanoparticles (Bi NPs) on their surface, which endowed the obtained Bi/HCNFs with excellent electroca...
Source: Molecules - May 4, 2023 Category: Chemistry Authors: Fengyi Wang Ye Li Chenglu Yan Qiuting Ma Xiaofeng Yang Huaqiao Peng Huiyong Wang Juan Du Baozhan Zheng Yong Guo Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3857: Cadmium Sulfide Nanoparticles: Preparation, Characterization, and Biomedical Applications
ad-Ali Shahbazi Cadmium sulfide nanoparticles (CdS NPs) have been employed in various fields of nanobiotechnology due to their proven biomedical properties. They are unique in their properties due to their size and shape, and they are popular in the area of biosensors, bioimaging, and antibacterial and anticancer applications. Most CdS NPs are generally synthesized through chemical, physical, or biological methods. Among these methods, biogenic synthesis has attracted more attention due to its high efficiency, environmental friendliness, and biocompatibility features. The green approach was found to be superior to othe...
Source: Molecules - May 2, 2023 Category: Chemistry Authors: Alireza Ghasempour Hamideh Dehghan Mehrnaz Ataee Bo Zhi Chen ZeQiang Zhao Mahsa Sedighi Xin Dong Guo Mohammad-Ali Shahbazi Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3811: Peroxidase-like Activity of CeO2 Nanozymes: Particle Size and Chemical Environment Matter
r K. Ivanov The enzyme-like activity of metal oxide nanoparticles is governed by a number of factors, including their size, shape, surface chemistry and substrate affinity. For CeO2 nanoparticles, one of the most prominent inorganic nanozymes that have diverse enzymatic activities, the size effect remains poorly understood. The low-temperature hydrothermal treatment of ceric ammonium nitrate aqueous solutions made it possible to obtain CeO2 aqueous sols with different particle sizes (2.5, 2.8, 3.9 and 5.1 nm). The peroxidase-like activity of ceria nanoparticles was assessed using the chemiluminescent method in differen...
Source: Molecules - April 29, 2023 Category: Chemistry Authors: Arina D. Filippova Madina M. Sozarukova Alexander E. Baranchikov Sergey Yu. Kottsov Kirill A. Cherednichenko Vladimir K. Ivanov Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3809: Acetogenins-Rich Fractions of Annona coriacea Suppress Human Glioblastoma Viability and Migration by Regulating Necroptosis and MMP-2 Activity In Vitro
. M. A. Ribeiro Glioblastoma (GBM) is an incurable primary brain tumor with a poor prognosis. Resection, radiation therapy, and temozolomide (TMZ) are insufficient to increase survival, making the treatment limited. Thus, the search for more effective and specific treatments is essential, making plants a promising source for elucidating new anti-glioblastoma compounds. Accordingly, this study investigated the effects of four fractions of hexane and ethyl acetate extract of Annona coriacea Mart., enriched with acetogenins, against GBM cell lines. All four fractions were selectively cytotoxic to GBM cells when compared t...
Source: Molecules - April 29, 2023 Category: Chemistry Authors: Lorena R. Sousa Ana Gabriela S. Oliveira Ant ônio Arantes Jo ão Gabriel M. Junqueira Gerso P. Alexandre Vanessa G. P. Severino Rui Manuel Reis Bonglee Kim Rosy I. M. A. Ribeiro Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3801: Anti-Inflammatory Effect of Ethanolic Extract from Tabebuia rosea (Bertol.) DC., Quercetin, and Anti-Obesity Drugs in Adipose Tissue in Wistar Rats with Diet-Induced Obesity
Flores Obesity is characterized by the excessive accumulation of fat, which triggers a low-grade chronic inflammatory process. Currently, the search for compounds with anti-obesogenic effects that help reduce body weight, as well as associated comorbidities, continues. Among this group of compounds are plant extracts and flavonoids with a great diversity of action mechanisms associated with their beneficial effects, such as anti-inflammatory effects and/or as signaling molecules. In the bark of Tabebuia rosea tree, there are different classes of metabolites with anti-inflammatory properties, such as quercetin. Therefor...
Source: Molecules - April 28, 2023 Category: Chemistry Authors: Alejandro Barrios-Nolasco Aar ón Domínguez-López Angel Miliar-Garc ía Jorge Cornejo-Garrido Mar ía Eugenia Jaramillo-Flores Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3793: Biological Selenite Reduction, Characterization and Bioactivities of Selenium Nanoparticles Biosynthesised by Pediococcus acidilactici DSM20284
Yuhua Shi Selenium (Se) is in great demand as a health supplement due to its superior reactivity and excellent bioavailability, despite selenium nanoparticles (SeNPs) having signs of minor toxicity. At present, the efficiency of preparing SeNPs using lactic acid bacteria is unsatisfactory. Therefore, a probiotic bacterial strain that is highly efficient at converting selenite to elemental selenium is needed. In our work, four selenite-reducing bacteria were isolated from soil samples. Strain LAB-Se2, identified as Pediococcus acidilactici DSM20284, had a reduction rate of up to 98% at ambient temperature. This strain c...
Source: Molecules - April 28, 2023 Category: Chemistry Authors: Qingdong Wang Chunyue Wang Shanshan Kuang Dezhen Wang Yuhua Shi Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3780: pH-Sensitive Gold Nanorods for Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Delivery and DNA-Binding Studies
s Tangoulis A facile experimental protocol for the synthesis of poly(ethylene glycol)-modified (PEGylated) gold nanorods (AuNRs@PEG) is presented as well as an effective drug loading procedure using the non-steroidal anti-inflammatory drug (NSAID) naproxen (NAP). The interaction of AuNRs@PEG and drug-loaded AuNRs (AuNRs@PEG@NAP) with calf-thymus DNA was studied at a diverse temperature revealing different interaction modes; AuNRs@PEG may interact via groove-binding and AuNRs@PEG@NAP may intercalate to DNA-bases. The cleavage activity of the gold nanoparticles for supercoiled circular pBR322 plasmid DNA was studied b...
Source: Molecules - April 27, 2023 Category: Chemistry Authors: Zygouri Bekiari Malis Karamanos Koutsakis Psomas Tangoulis Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3757: Realizing Ultrafast and Robust Sodium-Ion Storage of Iron Sulfide Enabled by Heteroatomic Doping and Regulable Interface Engineering
g Liu Hongyu Mi Fe-based sulfides are a promising type of anode material for sodium-ion batteries (SIBs) due to their high theoretical capacities and affordability. However, these materials often suffer from issues such as capacity deterioration and poor conductivity during practical application. To address these challenges, an N-doped Fe7S8 anode with an N, S co-doped porous carbon framework (PPF-800) was synthesized using a template-assisted method. When serving as an anode for SIBs, it delivers a robust and ultrafast sodium storage performance, with a discharge capacity of 489 mAh g−1 after 500 cycle...
Source: Molecules - April 27, 2023 Category: Chemistry Authors: Jinke Shen Naiteng Wu Wei Xie Qing Li Donglei Guo Jin Li Guilong Liu Xianming Liu Hongyu Mi Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3736: Platinum Nanoparticles Loaded Graphitic Carbon Nitride Nanosheets with Enhanced Peroxidase-like Activity for H2O2 and Oxidase-Based Sensing
e Qing Chunxia Song Platinum nanoparticles (PtNPs) are classical peroxidase-like nanozyme; self-agglomeration of nanoparticles leads to the undesirable reduction in stability and catalytic activity. Herein, a hybrid peroxidase-like nanocatalyst consisting of PtNPs in situ growing on g–C3N4 nanosheets with enhanced peroxidase-mimic catalytic activity (PtNP@g–C3N4 nanosheets) was prepared for H2O2 and oxidase-based colorimetric assay. g–C3N4 nanosheets can be used as carriers to solve the problem of poor stability of PtNPs. We observed that the catalytic ability could be mainta...
Source: Molecules - April 26, 2023 Category: Chemistry Authors: Gege Yang Ying Chen Rui Shi Rongrong Chen Shanshan Gao Xin Zhang Yuan Rao Ying Lu Yuancheng Peng Zhihe Qing Chunxia Song Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3699: Facile Synthesis, Characterization, and Antimicrobial Assessment of a Silver/Montmorillonite Nanocomposite as an Effective Antiseptic against Foodborne Pathogens for Promising Food Protection
. El-Newehy Foodborne pathogens can have devastating repercussions and significantly threaten public health. Therefore, it is indeed essential to guarantee the sustainability of our food production. Food preservation and storage using nanocomposites is a promising strategy. Accordingly, the present research’s objectives were to identify and isolate a few foodborne pathogens from food products, (ii) synthesize and characterize silver nanoparticles (AgNPs) using wet chemical reduction into the lamellar space layer of montmorillonite (MMT), and (iii) investigate the antibacterial potential of the AgNPs/MMT n...
Source: Molecules - April 25, 2023 Category: Chemistry Authors: Mohsen M. El-Sherbiny Reny P. Devassy Mohamed E. El-Hefnawy Soha T. Al-Goul Mohammed I. Orif Mohamed H. El-Newehy Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3692: Biological Activities of Sargassum Algae Mediated ZnO and Co Doped ZnO Nanoparticles as Enhanced Antioxidant and Anti-Diabetic Agents
Stefano Bellucci Brown macroalgae (BMG) were used as carriers for ZnO (ZnO/BMG) and cobalt-doped ZnO (Co-ZnO/BMG) via facile microwave-assisted hydrothermal synthesis. The multifunctional structures of synthesized composites were evaluated as enhanced antioxidant and anti-diabetic agents based on the synergistic effects of ZnO, Co-ZnO, and BMG. BMG substrate incorporation and cobalt doping notably enhanced the bioactivity of the synthesized ZnO nanoparticles. As an antioxidant, the Co-ZnO/BMG composite exhibited highly effective scavenging properties for the common free reactive oxygen radicals (DPPH [89.6 &pl...
Source: Molecules - April 25, 2023 Category: Chemistry Authors: Hassan Ahmed Rudayni Abdelrahman M. Rabie Malak Aladwani Lina M. Alneghery Gasem M. Abu-Taweel Wail Al Zoubi Ahmed A. Allam Mostafa R. Abukhadra Stefano Bellucci Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3666: Biosynthesis of Silver Nanoparticles and Exploring Their Potential of Reducing the Contamination of the In Vitro Culture Media and Inducing the Callus Growth of Rumex nervosus Explants
Kahkashan Perveen Among biological methods, green synthesis of the nanomaterials using plant extracts was shown to be an environmentally friendly, economical, and simple approach. In the current study, the biogenic synthesis of silver nanoparticles (AgNPs) was achieved using the leaf extract of Hibiscus tiliaceus, in order to prevent the contamination of the tissue culture media and induce callus growth. The nanostructures of the fabricated AgNPs were characterized using UV–visible spectroscopy, Fourier transform infra-red spectra (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), ...
Source: Molecules - April 23, 2023 Category: Chemistry Authors: Norah S. Alfarraj Mohamed Tarroum Fahad Al-Qurainy Mohammad Nadeem Salim Khan Abdalrhaman M. Salih Hassan O. Shaikhaldein Abdulrahman Al-Hashimi Saleh Alansi Kahkashan Perveen Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3661: The Antimicrobial Peptide & gamma;-Thionin from Habanero Chile (Capsicum chinense) Induces Caspase-Independent Apoptosis on Human K562 Chronic Myeloid Leukemia Cells and Regulates Epigenetic Marks
This study shows that defensin γ-thionin (Capsicum chinense) is cytotoxic to the K562 leukemia cells with an IC50 = 290 μg/mL (50.26 μM) but not for human peripheral blood mononuclear cells. Results showed that γ-thionin did not affect the membrane potential; however, the peptide modified the mitochondrial membrane potential (ΔΨm) and the intracellular calcium release. In addition, γ-thionin induced apoptosis in K562 cells, but the activation of caspases 8 and 9 was not detected. Moreover, the activation of calpains was detected at on...
Source: Molecules - April 23, 2023 Category: Chemistry Authors: Luis Jos é Flores-Alvarez Paola Jim énez-Alcántar Alejandra Ochoa-Zarzosa Joel E. L ópez-Meza Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3671: Anticancer Potentials of the Lignan Magnolin: A Systematic Review
In conclusion, magnolin showed robust anticancer activity against many cancer cell lines by altering several cancer signaling pathways in various non- and pre-clinical experimental models, making it a promising plant-derived chemotherapeutic option for further clinical research.
Source: Molecules - April 23, 2023 Category: Chemistry Authors: Md. Shimul Bhuia Polrat Wilairatana Raihan Chowdhury Asraful Islam Rakib Hossam Kamli Ahmad Shaikh Henrique D. M. Coutinho Muhammad Torequl Islam Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3639: Biological Potential of Carnivorous Plants from Nepenthales
achno Since Charles Darwin and his book carnivorous plants have aroused interest and heated debate. In addition, there is growing interest in this group of plants as a source of secondary metabolites and in the application of their biological activity. The aim of this study was to trace the recent literature in search of the application of extracts obtained from families Droseraceae, Nepenthaceae, and Drosophyllaceae to show their biological potential. The data collected in the review clearly indicate that the studied Nepenthales species have great biological potential in terms of antibacterial, antifungal, antioxidant...
Source: Molecules - April 21, 2023 Category: Chemistry Authors: Magdalena W ójciak Marcin Feldo Piotr Stolarczyk Bartosz J. P łachno Tags: Review Source Type: research