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Total 2868 results found since Jan 2013.

Molecules, Vol. 28, Pages 5328: Preparation of Surface-Active Hyperbranched-Polymer-Encapsulated Nanometal as a Highly Efficient Cracking Catalyst for In Situ Combustion of Heavy Oil
ng Fan Qilei Tong In situ combustion of heavy oil is currently the most suitable thermal method that meets energy consumption and carbon dioxide emission requirements for heavy oil recovery. The combustion catalyst needs to perform multiple roles for application; it should be capable of catalyzing heavy oil combustion at high temperatures, as well as be able to migrate in the geological formation for injection. In this work, a hyperbranched polymer composite nanometal fluid was used as the injection vector for a heavy oil in situ combustion catalyst, which enabled the catalyst to rapidly migrate to the surface of the...
Source: Molecules - July 11, 2023 Category: Chemistry Authors: Ao Sun Chenyang Yao Lifeng Zhang Yanmin Sun Jun Nan Houkai Teng Jiazhong Zang Lishan Zhou Zhenzhong Fan Qilei Tong Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5305: Nanoparticle-Based Antioxidants in Stress Signaling and Programmed Cell Death in Breast Cancer Treatment
Diantini Breast cancer (BC) is a complex and heterogeneous disease, and oxidative stress is a hallmark of BC. Oxidative stress is characterized by an imbalance between the production of reactive oxygen species (ROS) and antioxidant defense mechanisms. ROS has been implicated in BC development and progression by inducing DNA damage, inflammation, and angiogenesis. Antioxidants have been shown to scavenge ROS and protect cells from oxidative damage, thereby regulating signaling pathways involved in cell growth, survival, and death. Plants contain antioxidants like ascorbic acid, tocopherols, carotenoids, and flavonoids,...
Source: Molecules - July 10, 2023 Category: Chemistry Authors: Yedi Herdiana Sriwidodo Sriwidodo Ferry Ferdiansyah Sofian Gofarana Wilar Ajeng Diantini Tags: Review Source Type: research

Molecules, Vol. 28, Pages 5304: Fabrication of Composite Gel Electrolyte and F-Doping Carbon/Silica Anode from Electro-Spun P(VDF-HFP)/Silica Composite Nanofiber Film for Advanced Lithium-Ion Batteries
gang Yang The aim of this work is to effectively combine the advantages of polymer and ceramic nanoparticles and improve the comprehensive performance of lithium-ion batteries (LIBs) diaphragm. A flexible film composed of electro-spun P(VDF-HFP) nanofibers covered by a layer of mesoporous silica (P(VDF-HFP)@SiO2) was synthesized via a sol–gel transcription method, then used as a scaffold to absorb organic electrolyte to make gel a electrolyte membrane (P(VDF-HFP)@SiO2-GE) for LIBs. The P(VDF-HFP)@SiO2-GE presents high electrolyte uptake (~1000 wt%), thermal stability (up to ~350 °C), ionic con...
Source: Molecules - July 10, 2023 Category: Chemistry Authors: Caiyuan Liu Xin Fang Hui Peng Yi Li Yonggang Yang Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5322: Phytofabrication of Selenium Nanoparticles with Moringa oleifera (MO-SeNPs) and Exploring Its Antioxidant and Antidiabetic Potential
e Hoon Tang The advancement in nanotechnology is the trigger for exploring the synthesis of selenium nanoparticles and their use in biomedicine. Therefore, this study aims to synthesize selenium nanoparticles using M. oleifera as a reducing agent and evaluate their antioxidant and antidiabetic potential. Our result demonstrated a change in the color of the mixture from yellow to red, and UV-Vis spectrometry of the suspension solution confirmed the formation of MO-SeNPs with a single absorbance peak in the range of 240–560 nm wavelength. FTIR analysis revealed several bioactive compounds, such as phenols a...
Source: Molecules - July 10, 2023 Category: Chemistry Authors: Anas Ahzaruddin Ahamad Tarmizi Nik Nasihah Nik Ramli Siti Hajar Adam Maisarah Abdul Mutalib Mohd Helmy Mokhtar Shirley Gee Hoon Tang Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5317: Interaction of Doxorubicin Embedded into Phospholipid Nanoparticles and Targeted Peptide-Modified Phospholipid Nanoparticles with DNA
antseva The interactions of dsDNA with new targeted drug delivery derivatives of doxorubicin (DOX), such as DOX embedded into phospholipid nanoparticles (NPhs) and DOX with the NGR targeted peptide-modified NPhs were studied electrochemically by differential pulse voltammetry technique. Screen-printed electrodes (SPEs), modified with stable fine dispersions of carbon nanotubes (CNTs), were used for quantitative electrochemical investigations of direct electrochemical oxidation of guanine, adenine, and thymine heterocyclic bases of dsDNA, and their changes in the presence of DOX nanoderivatives. Analysing the shifts of ...
Source: Molecules - July 10, 2023 Category: Chemistry Authors: Veronica V. Pronina Lyubov V. Kostryukova Tatiana V. Bulko Victoria V. Shumyantseva Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5314: Coriandrum sativum and Its Utility in Psychiatric Disorders
ra-Ruiz The negative impact on worldwide social well-being by the increasing rate of psychiatric diseases has led to a continuous new drug search. Even though the current therapeutic options exert their activity on multiple neurological targets, these have various adverse effects, causing treatment abandonment. Recent research has shown that Coriandrum sativum offers a rich source of metabolites, mainly terpenes and flavonoids, as useful agents against central nervous system disorders, with remarkable in vitro and in vivo activities on models related to these pathologies. Furthermore, studies have revealed that some co...
Source: Molecules - July 10, 2023 Category: Chemistry Authors: Anislada Santib áñez Enrique Jim énez-Ferrer Paola Isabel Angulo-Bejarano Ashutosh Sharma Maribel Herrera-Ruiz Tags: Review Source Type: research

Molecules, Vol. 28, Pages 5296: A Facile Preparation of Sandwich-Structured Pd/Polypyrrole-Graphene/Pd Catalysts for Formic Acid Electro-Oxidation
In this study, a new sandwich-structured Pd/polypyrrole-graphene/Pd (Pd/PPy-Gns/Pd)-modified glassy carbon electrode (GCE) was prepared using a simple constant potential (CP) electrodeposition technique. On the basis of the unique synthetic procedure and structural advantages, the Pd/PPy-Gns/Pd shows a fast charge/mass transport rate, high electrocatalytic activity, and great stability for formic acid electro-oxidation (FAO). The mass activity of Pd/PPy-Gns/Pd electrode reaches 917 mA·mg−1Pd. The excellent catalytic activity is mainly due to the uniform embedding of Pd nanoparticles on the poly...
Source: Molecules - July 9, 2023 Category: Chemistry Authors: Zhenjiang Lu Wenjin Qin Juan Ma Yali Cao Shujuan Bao Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5293: Deep Eutectic Solvents: Properties and Applications in CO2 Separation
ska Nowadays, many researchers are focused on finding a solution to the problem of global warming. Carbon dioxide is considered to be responsible for the “greenhouse” effect. The largest global emission of industrial CO2 comes from fossil fuel combustion, which makes power plants the perfect point source targets for immediate CO2 emission reductions. A state-of-the-art method for capturing carbon dioxide is chemical absorption using an aqueous solution of alkanolamines, most frequently a 30% wt. solution of monoethanolamine (MEA). Unfortunately, the usage of alkanolamines has a number of dra...
Source: Molecules - July 8, 2023 Category: Chemistry Authors: Iwona Cichowska-Kopczy ńska Bartosz Nowosielski Dorota Warmi ńska Tags: Review Source Type: research

Molecules, Vol. 28, Pages 5264: Hemostasis Strategies and Recent Advances in Nanomaterials for Hemostasis
Da Huang The development of materials that effectively stop bleeding and prevent wound adhesion is essential in both military and medical fields. However, traditional hemostasis methods, such as cautery, tourniquets, and gauze, have limitations. In recent years, new nanomaterials have gained popularity in medical and health fields due to their unique microstructural advantages. Compared to traditional materials, nanomaterials offer better adhesion, versatility, and improved bioavailability of traditional medicines. Nanomaterials also possess advantages such as a high degree and stability, self-degradation, fewer sid...
Source: Molecules - July 7, 2023 Category: Chemistry Authors: Jian Du Jingzhong Wang Tao Xu Hai Yao Lili Yu Da Huang Tags: Review Source Type: research

Molecules, Vol. 28, Pages 5233: Fabrication, Characterization and Biomedical Evaluation of a Statistically Optimized Gelatin Scaffold Enriched with Co-Drugs Loaded into Controlled-Release Silica Nanoparticles
ha Shabbir Ghulam Abbas The current study focused on the fabrication of a well-designed, biocompatible, physically stable, non-irritating and highly porous gelatin scaffold loaded with controlled-release triamcinolone acetonide (TA) and econazole nitrate (EN) co-loaded into mesoporous silica nanoparticles (EN-TA-loaded MSNs) to provide a better long-lasting antifungal therapeutic effect with minimal unfavorable effects. Optimization of the MSNs-loaded scaffold was performed using central composite rotatable design (CCRD), where the effect of gelatin concentration (X1), plasticizer (X2) and freezing time (X3) on the e...
Source: Molecules - July 5, 2023 Category: Chemistry Authors: Hina Younis Hafeez Ullah Khan Safirah Maheen Malik Saadullah Shahid Shah Nabeel Ahmad Sameer Alshehri Mohammed Ali A. Majrashi Abdullah Alsalhi Rida Siddique Mehwish Andleeb Saleha Shabbir Ghulam Abbas Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5228: A General Protocol for Synthesizing Thiolated Folate Derivatives
Jianguo Tang Folic acid (FA) has shown great potential in the fields of targeted drug delivery and disease diagnosis due to its highly tumor-targeting nature, biocompatibility, and low cost. However, FA is generally introduced in targeted drug delivery systems through macromolecular linkage via complex synthetic processes, resulting in lower yields and high costs. In this work, we report a general protocol for synthesizing thiolated folate derivatives. The small molecule thiolated folate (TFa) was first synthesized with a purity higher than 98.20%. First, S-S-containing diol was synthesized with a purity higher than 9...
Source: Molecules - July 5, 2023 Category: Chemistry Authors: Jie Li Yao Wang Liangang Shan Lei Qian Wenchao Wang Jixian Liu Jianguo Tang Tags: Communication Source Type: research

Molecules, Vol. 28, Pages 5206: Evaluation of Novel B1R/B2R Agonists Containing TRIOZAN & trade; Nanoparticles for Targeted Brain Delivery of Antibodies in a Mouse Model of Alzheimer Disease
Molecules, Vol. 28, Pages 5206: Evaluation of Novel B1R/B2R Agonists Containing TRIOZAN™ Nanoparticles for Targeted Brain Delivery of Antibodies in a Mouse Model of Alzheimer Disease Molecules doi: 10.3390/molecules28135206 Authors: Maxime Gagnon Martin Savard Thi Minh Hue Tran Laurence Vincent Alexandre Moquin Philippe Tremblay Xavier Roucou Yves Dory Fernand Gobeil The blood–brain barrier (BBB) is a major obstacle to the development of effective therapeutics for central nervous system (CNS) disorders, including Alzheimer’s disease (AD). This has been particula...
Source: Molecules - July 4, 2023 Category: Chemistry Authors: Maxime Gagnon Martin Savard Thi Minh Hue Tran Laurence Vincent Alexandre Moquin Philippe Tremblay Xavier Roucou Yves Dory Fernand Gobeil Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5198: Usnic Acid-Loaded Magnetite Nanoparticles & mdash;A Comparative Study between Synthesis Methods
Molecules, Vol. 28, Pages 5198: Usnic Acid-Loaded Magnetite Nanoparticles—A Comparative Study between Synthesis Methods Molecules doi: 10.3390/molecules28135198 Authors: Cristina Chircov Alexandra Cătălina Bîrcă Lorena Alexandra Dănciulescu Ionela Andreea Neacșu Ovidiu-Cristian Oprea Roxana-Doina Trușcă Ecaterina Andronescu Since cancer is a continuously increasing concern for the general population, more efficient treatment alternatives ought to be developed. In this regard, a promising direction is represented by the use of magnetite nanoparticles (MNPs) to act both as a nanocarrier ...
Source: Molecules - July 4, 2023 Category: Chemistry Authors: Cristina Chircov Alexandra C ătălina Bîrcă Lorena Alexandra D ănciulescu Ionela Andreea Neac șu Ovidiu-Cristian Oprea Roxana-Doina Tru șcă Ecaterina Andronescu Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5190: Broad-Spectrum, Potent, and Durable Ceria Nanoparticles Inactivate RNA Virus Infectivity by Targeting Virion Surfaces and Disrupting Virus & ndash;Receptor Interactions
Molecules, Vol. 28, Pages 5190: Broad-Spectrum, Potent, and Durable Ceria Nanoparticles Inactivate RNA Virus Infectivity by Targeting Virion Surfaces and Disrupting Virus–Receptor Interactions Molecules doi: 10.3390/molecules28135190 Authors: Candace R. Fox Kritika Kedarinath Craig J. Neal Jeremy Sheiber Elayaraja Kolanthai Udit Kumar Christina Drake Sudipta Seal Griffith D. Parks There is intense interest in developing long-lasting, potent, and broad-spectrum antiviral disinfectants. Ceria nanoparticles (CNPs) can undergo surface redox reactions (Ce3+ ↔ Ce4+) to generate ROS ...
Source: Molecules - July 4, 2023 Category: Chemistry Authors: Candace R. Fox Kritika Kedarinath Craig J. Neal Jeremy Sheiber Elayaraja Kolanthai Udit Kumar Christina Drake Sudipta Seal Griffith D. Parks Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5188: Precipitation of Pt, Pd, Rh, and Ru Nanoparticles with Non-Precious Metals from Model and Real Multicomponent Solutions
This article presents studies on the precipitation of Pt, Pd, Rh, and Ru nanoparticles (NPs) from model and real multicomponent solutions using sodium borohydride, ascorbic acid, sodium formate, and formic acid as reducing agents and polyvinylpyrrolidone as a stabilizing agent. As was expected, apart from PGMs, non-precious metals were coprecipitated. The influence of the addition of non-precious metal ions into the feed solution on the precipitation yield and catalytic properties of the obtained precipitates was studied. A strong reducing agent, NaBH4 precipitates Pt, Pd, Rh, Fe and Cu NPs in most cases with an efficiency...
Source: Molecules - July 4, 2023 Category: Chemistry Authors: Martyna Rzelewska-Piekut Zuzanna Wola ńczyk Marek Nowicki Magdalena Regel-Rosocka Tags: Article Source Type: research