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Total 2868 results found since Jan 2013.

Molecules, Vol. 28, Pages 6132: Tolyporphins & ndash;Exotic Tetrapyrrole Pigments in a Cyanobacterium & mdash;A Review
Molecules, Vol. 28, Pages 6132: Tolyporphins–Exotic Tetrapyrrole Pigments in a Cyanobacterium—A Review Molecules doi: 10.3390/molecules28166132 Authors: Kathy-Uyen Nguyen Yunlong Zhang Qihui Liu Ran Zhang Xiaohe Jin Masahiko Taniguchi Eric S. Miller Jonathan S. Lindsey Tolyporphins were discovered some 30 years ago as part of a global search for antineoplastic compounds from cyanobacteria. To date, the culture HT-58-2, comprised of a cyanobacterium–microbial consortium, is the sole known producer of tolyporphins. Eighteen tolyporphins are now known—each ...
Source: Molecules - August 18, 2023 Category: Chemistry Authors: Kathy-Uyen Nguyen Yunlong Zhang Qihui Liu Ran Zhang Xiaohe Jin Masahiko Taniguchi Eric S. Miller Jonathan S. Lindsey Tags: Review Source Type: research

Molecules, Vol. 28, Pages 6110: Effect of Cd2+ Substitution on Structural & ndash;Magnetic and Dielectric Properties of Ni & ndash;Cu & ndash;Zn Spinel Ferrite Nanomaterials by Sol & ndash;Gel
Molecules, Vol. 28, Pages 6110: Effect of Cd2+ Substitution on Structural–Magnetic and Dielectric Properties of Ni–Cu–Zn Spinel Ferrite Nanomaterials by Sol–Gel Molecules doi: 10.3390/molecules28166110 Authors: Hu Yang Xingxing Yang Jinpei Lin Fang Yang Yun He Qing Lin CdxNi0.5−xCu0.2Zn0.3Fe2O4 (0 ≤ x ≤ 0.50) ferrite with a spinel structure was prepared using the sol–gel self-propagation method. The effects of Cd2+ doping on the structure, morphology, dielectric, and magnetic properties of Ni–Cu&amp...
Source: Molecules - August 17, 2023 Category: Chemistry Authors: Hu Yang Xingxing Yang Jinpei Lin Fang Yang Yun He Qing Lin Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6107: Effects of Different Types of Stabilizers on the Properties of Foam Detergent Used for Radioactive Surface Contamination
i Yu Jiao Compared with high-pressure water and reagent washing decontamination, foam decontamination has a promising application due to its ability to significantly reduce the volume of radioactive waste liquids and effectively decontaminate the inner surface of the pipes, the interior of the large cavities, and the vertical walls. However, the foam is less stable, leading to a low decontamination rate. Currently, three main types of stabilizers with different stabilizing mechanisms, namely nanoparticles, polymers, and cosurfactants, are used to improve foam stability and thus increase the decontamination rate. Nano...
Source: Molecules - August 17, 2023 Category: Chemistry Authors: Hao Zhang Lili Liang Hailing Xi Xiaoyan Lin Zhanguo Li Yu Jiao Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6099: Different Size Formulations of Fluopyram: Preparation, Antifungal Activity, and Accumulation in the Fungal Pathogen Botrytis cinerea
In this study, three solid fluopyram formulations with varying particle sizes were developed, and the mechanisms underlying the difference in the antifungal activity among these formulations were investigated. Wet media milling combined with freeze drying was used to prepare fluopyram nanoparticles (FLU-NS) and a micron-sized solid formulation (FLU-MS), and a jet grinding mill was employed to fabricate fluopyram wettable powder (FLU-WP). The mean particle sizes of FLU-NS, FLU-MS, and FLU-WP were 366.8 nm, 2.99 μm, and 10.16 μm, respectively. Notably, FLU-NS displayed a toxicity index against Botrytis ...
Source: Molecules - August 17, 2023 Category: Chemistry Authors: Yinmin Wang Sida Zhang Yong Xu Haiyun Li Ruihua Zhang Dong Chen Jianfu Xu Xuemin Wu Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6095: Metal & ndash;Organic Frameworks as Formose Reaction Catalysts with Enhanced Selectivity
Molecules, Vol. 28, Pages 6095: Metal–Organic Frameworks as Formose Reaction Catalysts with Enhanced Selectivity Molecules doi: 10.3390/molecules28166095 Authors: Valentina Balloi Manuel Antonio Diaz-Perez Mayra Anabel Lara-Angulo David Villalgordo-Hernández Javier Narciso Enrique V. Ramos-Fernandez Juan Carlos Serrano-Ruiz The formose reaction is an autocatalytic series of aldol condensations that allows one to obtain monosaccharides from formaldehyde. The formose reaction suffers from a lack of selectivity, which hinders practical applications at the industrial level. Over the years, many a...
Source: Molecules - August 17, 2023 Category: Chemistry Authors: Valentina Balloi Manuel Antonio Diaz-Perez Mayra Anabel Lara-Angulo David Villalgordo-Hern ández Javier Narciso Enrique V. Ramos-Fernandez Juan Carlos Serrano-Ruiz Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6040: A New Impregnated Adsorbent for Noble Metal Ion Sorption
jcik Noble metals (NM) such as gold, platinum, palladium, and rhodium are widely applied in the electronics and automotive industries. Thus, the search for cheap and selective sorbents for noble metals is economically justified. Nitrolite does not sorb noble metal ions. A new impregnated sorbent was prepared. The natural sorbent Nitrolite was impregnated with Aliquat 336 using a new warm impregnation method. After the impregnation process, Nitrolite adsorbed platinum(IV), palladium(II), and gold(III) ions from the chloride solutions. The values of the sorption capacity for palladium(II) and platinum(IV) ions were 47.63...
Source: Molecules - August 13, 2023 Category: Chemistry Authors: Zbigniew Hubicki Karolina Zinkowska Grzegorz W ójcik Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6038: Recent Progress of Preparation Strategies in Organic Nanoparticles for Cancer Phototherapeutics
gliang Li Phototherapy has the advantages of being a highly targeted, less toxic, less invasive, and repeatable treatment, compared with conventional treatment methods such as surgery, chemotherapy, and radiotherapy. The preparation strategies are significant in order to determine the physical and chemical properties of nanoparticles. However, choosing appropriate preparation strategies to meet applications is still challenging. This review summarizes the recent progress of preparation strategies in organic nanoparticles, mainly focusing on the principles, methods, and advantages of nanopreparation strategies. In addit...
Source: Molecules - August 13, 2023 Category: Chemistry Authors: Quanquan Xie Jiayi Tang Shengze Guo Qi Zhao Shengliang Li Tags: Review Source Type: research

Molecules, Vol. 28, Pages 6015: A New Perspective for the Treatment of Alzheimer & rsquo;s Disease: Exosome-like Liposomes to Deliver Natural Compounds and RNA Therapies
Molecules, Vol. 28, Pages 6015: A New Perspective for the Treatment of Alzheimer’s Disease: Exosome-like Liposomes to Deliver Natural Compounds and RNA Therapies Molecules doi: 10.3390/molecules28166015 Authors: Joana Ribeiro Ivo Lopes Andreia Castro Gomes With the increment of the aging population in recent years, neurodegenerative diseases exert a major global disease burden, essentially as a result of the lack of treatments that stop the disease progression. Alzheimer’s Disease (AD) is an example of a neurodegenerative disease that affects millions of people globally, with no effectiv...
Source: Molecules - August 11, 2023 Category: Chemistry Authors: Joana Ribeiro Ivo Lopes Andreia Castro Gomes Tags: Review Source Type: research

Molecules, Vol. 28, Pages 6023: Deep Eutectic Solvents Formed by Glycerol and Xylitol, Fructose and Sorbitol: Effect of the Different Sugars in Their Physicochemical Properties
In this study, three deep eutectic solvents (DESs) formed by glycerol and xylitol, fructose and sorbitol and water in the molar ratio 1:2:3 were prepared and several physicochemical properties (refractive index, density, surface tension, viscosity, speed of sound, isobaric heat capacity and isentropic compressibility) were measured and analyzed in the 278.15–338.15 K temperature range. The results indicate a linear dependence with temperature for the following properties: surface tension, refractive index, density and isobaric molar heat capacity while viscosity values have been fitted to the Vogel&nd...
Source: Molecules - August 11, 2023 Category: Chemistry Authors: Laura Lomba Álvaro Werner Beatriz Giner Carlos Lafuente Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5970: MOF-Based Biosensors for the Detection of Carcinoembryonic Antigen: A Concise Review
ish Cancer has been considered one of the most serious diseases in recent decades. Early diagnosis of cancer is a crucial step for expedited treatment. Ideally, detection of cancer biomarkers, which are usually elevated because of cancer, is the most straightforward approach to detecting cancer. Among these biomarkers, the carcinoembryonic antigen (CEA) is considered one of the most important tumor markers for colorectal cancer. The CEA has also been recognized as a biomarker for other types of cancers, including breast, gastric, ovarian, pancreatic, and lung cancers. Typically, conventional CEA testing depends on immu...
Source: Molecules - August 9, 2023 Category: Chemistry Authors: May R. Ibrahim Yaser E. Greish Tags: Review Source Type: research

Molecules, Vol. 28, Pages 5981: Incorporation of Copper Nanoparticles on Electrospun Polyurethane Membrane Fibers by a Spray Method
In this study, a combined electrospinning/spray technique was employed to fabricate electrospun polyurethane membranes loaded with copper nanoparticles at different surface densities (10, 20, 25, or 30 μg/cm2). This method allows particle deposition onto the surface of the membranes without the use of chemical agents. SEM images showed that polyurethane fibers own homogeneous thickness (around 650 nm), and that spray-deposited copper nanoparticles are evenly distributed. STEM-EDX demonstrated that copper nanoparticles are deposited onto the surface of the fibers and are not covered by polyurethane. Moreover, a u...
Source: Molecules - August 9, 2023 Category: Chemistry Authors: Tamer Al Kayal Giulia Giuntoli Aida Cavallo Anissa Pisani Paola Mazzetti Rossella Fonnesu Alfredo Rosellini Mauro Pistello Mario D ’Acunto Giorgio Soldani Paola Losi Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5920: Selenium Nanoparticles Control H1N1 Virus by Inhibiting Inflammatory Response and Cell Apoptosis
This study focuses on the mechanism of selenium nanoparticles against an H1N1 influenza virus infection in vivo. The results showed that the selenium levels in the body decreased after an H1N1 virus infection, and inflammatory factors in the lung tissues increased abnormally, leading to the onset and aggravation of an inflammatory response. The H1N1 virus infection also led to the excessive activation of apoptotic pathways in the body and induced the apoptosis of tissue cells. In addition, this study found that SeNPs can alleviate this phenomenon. All results showed that SeNPs are promising inhibitors for controlling influ...
Source: Molecules - August 7, 2023 Category: Chemistry Authors: Jingyao Su Jia Lai Jiali Li Chuqing Li Xia Liu Chenyang Wang Bing Zhu Yinghua Li Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5914: Computer-Aided Drug Design of Novel Derivatives of 2-Amino-7,9-dihydro-8H-purin-8-one as Potent Pan-Janus JAK3 Inhibitors
In this study, the 3D-QSAR approach is employed to predict new JAK3 inhibitors. Two robust models, both field-based with R2 = 0.93, R = 0.96, and Q2 = 87, and atom-based with R2 = 0.94, R = 0.97, and Q2 = 86, yielded good results by identifying groups that may readily direct their interaction. A reliable pharmacophore model, DHRRR1, was provided in this work to enable the clear characterization of chemical features, leading to the design of 13 inhibitors with their pIC50 values. The DHRRR1 model yielded a validation result with a ROC value of 0.87. Five promising inhibitors were selected for further study based on an ADMET...
Source: Molecules - August 6, 2023 Category: Chemistry Authors: Abdelmoujoud Faris Ibrahim M. Ibrahim Omkulthom Al kamaly Asmaa Saleh Menana Elhallaoui Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5905: Exploring Nanocarriers as Treatment Modalities for Skin Cancer
Md. Faheem Haider Cancer is a progressive disease of multi-factorial origin that has risen worldwide, probably due to changes in lifestyle, food intake, and environmental changes as some of the reasons. Skin cancer can be classified into melanomas from melanocytes and nonmelanoma skin cancer (NMSC) from the epidermally-derived cell. Together it constitutes about 95% of skin cancer. Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (CSCC) are creditworthy of 99% of NMSC due to the limited accessibility of conventional formulations in skin cancer cells of having multiple obstacles in treatment reply to t...
Source: Molecules - August 5, 2023 Category: Chemistry Authors: Mohammad Adnan Md. Habban Akhter Obaid Afzal Abdulmalik S. A. Altamimi Irfan Ahmad Manal A. Alossaimi Mariusz Jaremko Abdul-Hamid Emwas Tanweer Haider Md. Faheem Haider Tags: Review Source Type: research

Molecules, Vol. 28, Pages 5838: The Role of Cerium Valence in the Conversion Temperature of H2Ti3O7 Nanoribbons to TiO2-B and Anatase Nanoribbons, and Further to Rutile
This study presents a straightforward method to obtain 1D TiO2 nanostructures decorated with CeO2 nanoparticles at the surface. As the precursor, we used H2Ti3O7 nanoribbons prepared from sodium titanate nanoribbons by ion exchange. Two cerium sources with an oxidation state of +3 and +4 were used to obtain mixed oxides. HAADF–STEM mapping of the Ce4+-modified nanoribbons revealed a thin continuous layer at the surface of the H2Ti3O7 nanoribbons, while Ce3+ cerium ions intercalated partially between the titanate layers. The phase composition and morphology changes were monitored during calcination between 620...
Source: Molecules - August 3, 2023 Category: Chemistry Authors: Polona Umek Michael D ürrschnabel Leopoldo Molina-Luna Sre čo Škapin Romana Cerc Koro šec Carla Bittencourt Tags: Article Source Type: research