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Total 2868 results found since Jan 2013.

Molecules, Vol. 28, Pages 3609: Myo-Inositol, Scyllo-Inositol, and Other Minor Carbohydrates as Authenticity Markers for the Control of Italian Bulk, Concentrate, and Rectified Grape Must
berto Larcher Myo-inositol polyalcohol is a characteristic component of natural and concentrated grape musts (CMs), and Regulation (EU) no. 1308/2013 prescribes its presence as a marker of the authenticity of rectified concentrated must (RCM). Other polyalcohols besides myo-inositol, such as scyllo-inositol or minor sugars, could be considered authenticity markers, but an extensive search in the literature yielded no exhaustively investigated study of their concentration variability in genuine products. The aim of this study was to create an extensive national data bank of minor carbohydrates profiles and investigate t...
Source: Molecules - April 20, 2023 Category: Chemistry Authors: Mauro Paolini Matteo Perini Letizia Allari Loris Tonidandel Fabio Finato Katia Guardini Roberto Larcher Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3604: Surface Modification of Bi2O3 Nanoparticles with Biotinylated & beta;-Cyclodextrin as a Biocompatible Therapeutic Agent for Anticancer and Antimicrobial Applications
Molecules, Vol. 28, Pages 3604: Surface Modification of Bi2O3 Nanoparticles with Biotinylated β-Cyclodextrin as a Biocompatible Therapeutic Agent for Anticancer and Antimicrobial Applications Molecules doi: 10.3390/molecules28083604 Authors: Jogy Alex Thomas V. Mathew Bismuth oxide nanoparticles with appropriate surface chemistry exhibit many interesting properties that can be utilized in a variety of applications. This paper describes a new route to the surface modification of bismuth oxide nanoparticles (Bi2O3 NPs) using functionalized beta-Cyclodextrin (β-CD) as a biocompatible system. Th...
Source: Molecules - April 20, 2023 Category: Chemistry Authors: Jogy Alex Thomas V. Mathew Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3602: Functionalization of Framboidal Phenylboronic Acid-Containing Nanoparticles via Aqueous Suzuki & ndash;Miyaura Coupling Reactions
Molecules, Vol. 28, Pages 3602: Functionalization of Framboidal Phenylboronic Acid-Containing Nanoparticles via Aqueous Suzuki–Miyaura Coupling Reactions Molecules doi: 10.3390/molecules28083602 Authors: André J. van der Vlies Urara Hasegawa Polymeric nanoparticles with reactive functional groups are an attractive platform for drug carriers that can be conjugated with drugs through a cleavable covalent linkage. Since the required functional groups vary depending on the drug molecule, there is a need for development of a novel post-modification method to introduce different functional groups to polymeri...
Source: Molecules - April 20, 2023 Category: Chemistry Authors: Andr é J. van der Vlies Urara Hasegawa Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3569: Chitosan-Coated Solid Lipid Nanoparticles as an Efficient Avenue for Boosted Biological Activities of Aloe perryi: Antioxidant, Antibacterial, and Anticancer Potential
In this study, ALP-loaded nanosystems were developed to improve their biological activity. Among different nanocarriers, solid lipid nanoparticles (ALP-SLNs), chitosan nanoparticles (ALP-CSNPs), and CS-coated SLNs (C-ALP-SLNs) were explored. The particle size, polydispersity index (PDI), zeta potential, encapsulation efficiency, and release profile were evaluated. Scanning electron microscopy was used to see the nanoparticles’ morphology. Moreover, the possible biological properties of ALP were assessed and evaluated. ALP extract contained 187 mg GAE/g extract and 33 mg QE/g extract in terms of total phenolic...
Source: Molecules - April 19, 2023 Category: Chemistry Authors: Tahany Saleh Aldayel Mohamed M. Badran Abdullah H. Alomrani Nora A. AlFaris Jozaa Z. Altamimi Ali S. Alqahtani Fahd A. Nasr Safina Ghaffar Raha Orfali Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3561: Nucleic Acid Probes in Bio-Imaging and Diagnostics: Recent Advances in ODN-Based Fluorescent and Surface-Enhanced Raman Scattering Nanoparticle and Nanostructured Systems
ru Rotaru Raman nanoparticle probes are a potent class of optical labels for the interrogation of pathological and physiological processes in cells, bioassays, and tissues. Herein, we review the recent advancements in fluorescent and Raman imaging using oligodeoxyribonucleotide (ODN)-based nanoparticles and nanostructures, which show promise as effective tools for live-cell analysis. These nanodevices can be used to investigate a vast number of biological processes occurring at various levels, starting from those involving organelles, cells, tissues, and whole living organisms. ODN-based fluorescent and Raman probes ha...
Source: Molecules - April 18, 2023 Category: Chemistry Authors: Monica-Cornelia Sardaru Narcisa-Laura Marangoci Rosanna Palumbo Giovanni N. Roviello Alexandru Rotaru Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3555: The Relationship between Gelation Behavior and the Amount of Polymer Dose per Silica Surface Area of & ldquo;Shake-Gels & rdquo; Consisting of Silica Nanoparticles and Poly(Ethylene Oxide)
Molecules, Vol. 28, Pages 3555: The Relationship between Gelation Behavior and the Amount of Polymer Dose per Silica Surface Area of “Shake-Gels” Consisting of Silica Nanoparticles and Poly(Ethylene Oxide) Molecules doi: 10.3390/molecules28083555 Authors: Shunsuke Sato Motoyoshi Kobayashi The understanding and control of the rheological behaviors of colloids and polymer mixtures is an important issue for scientific interests and industrial applications. Aqueous mixed suspensions of silica nanoparticles and poly(ethylene oxide) (PEO) under certain conditions are interesting systems called &...
Source: Molecules - April 18, 2023 Category: Chemistry Authors: Shunsuke Sato Motoyoshi Kobayashi Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3542: Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC
This study may provide a promising analytical approach with extraordinary column efficiency, resolution, and speed for the separation of complex samples.
Source: Molecules - April 17, 2023 Category: Chemistry Authors: Qing Liu Chao Yan Yan Wang Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3532: Synthesis, Characterization and Biological Activities of Zinc Oxide Nanoparticles Derived from Secondary Metabolites of Lentinula edodes
han Yean Yean Zinc oxide nanoparticles (ZnO NPs) are the second most prevalent metal oxide, owing to their characteristics of low cost, safe, and easily prepared. ZnO NPs have been found to exhibit unique properties which show their potential to be used in various therapies. Numerous techniques have been devised for the manufacture of zinc oxide because it is one of the nanomaterials that has received major research interest. Mushroom sources are proven to be efficient, ecologically friendly, inexpensive, and safe for humankind. In the current study, an aqueous fraction of methanolic extract of Lentinula edodes (L. edo...
Source: Molecules - April 17, 2023 Category: Chemistry Authors: Zeemal Seemab Amin Muhammad Afzal Jamshaid Ahmad Naveed Ahmed Basit Zeshan Nik Haszroel Hysham Nik Hashim Chan Yean Yean Tags: Article Source Type: research

Molecules, Vol. 28, Pages 3520: Silver Nanoparticles for Waste Water Management
thu Uthayakumar Rapidly increasing industrialisation has human needs, but the consequences have added to the environmental harm. The pollution caused by several industries, including the dye industries, generates a large volume of wastewater containing dyes and hazardous chemicals that drains industrial effluents. The growing demand for readily available water, as well as the problem of polluted organic waste in reservoirs and streams, is a critical challenge for proper and sustainable development. Remediation has resulted in the need for an appropriate alternative to clear up the implications. Nanotechnology is an eff...
Source: Molecules - April 17, 2023 Category: Chemistry Authors: Geetha Palani Herri Trilaksana R. Merlyn Sujatha Karthik Kannan Sundarakannan Rajendran Kinga Korniejenko Marek Nykiel Marimuthu Uthayakumar Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3518: Notoamide R: A Prominent Diketopiperazine Fermentation Metabolite amongst Others of Aspergillus ochraceus in the Absence of Ochratoxins
umont Ochratoxin A is historically the most notable secondary metabolite of Aspergillus ochraceus on account of its toxicity to animals and fish. Currently, over 150 compounds of diverse structure and biosynthesis is a challenge to predict the array for any particular isolate. A brief focus 30 years ago on the failure to produce ochratoxins in foods in Europe and the USA revealed consistent failures to produce ochratoxin A by isolates from some USA beans. Analysis for familiar or novel metabolites particularly focused on a compound for which mass and NMR analyses were inconclusive. Resort to 14C-labelled biosynthetic p...
Source: Molecules - April 17, 2023 Category: Chemistry Authors: Peter Mantle Andrew Roberts Claire Beaumont Tags: Communication Source Type: research

Molecules, Vol. 28, Pages 3513: Lignin-Based Catalysts for C & ndash;C Bond-Forming Reactions
Molecules, Vol. 28, Pages 3513: Lignin-Based Catalysts for C–C Bond-Forming Reactions Molecules doi: 10.3390/molecules28083513 Authors: Cristina del Mar García Martín José Ignacio Hernández García Sebastián Bonardd David Díaz Díaz Carbon–carbon (C–C) bond formation is the key reaction in organic synthesis to construct the carbon framework of organic molecules. The continuous shift of science and technology toward eco-friendly and sustainable resources and processes has stimulated the development of catalytic processes for C–C bond formation based on ...
Source: Molecules - April 16, 2023 Category: Chemistry Authors: Cristina del Mar Garc ía Martín Jos é Ignacio Hernández García Sebasti án Bonardd David D íaz Díaz Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3460: Risk Assessment of Trigonelline in Coffee and Coffee By-Products
enmeier Trigonelline is a bioactive pyridine alkaloid that occurs naturally in high concentrations in coffee (up to 7.2 g/kg) and coffee by-products (up to 62.6 g/kg) such as coffee leaves, flowers, cherry husks or pulp, parchment, silver skin, and spent grounds. In the past, coffee by-products were mostly considered waste and discarded. In recent years, however, the use of coffee by-products as food has attracted interest because of their economic and nutritional value and the environmental benefits of sustainable resource use. Their authorization as so-called novel foods in the European Union may lead to increased or...
Source: Molecules - April 14, 2023 Category: Chemistry Authors: Nick Konstantinidis Heike Franke Steffen Schwarz Dirk W. Lachenmeier Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3475: Exploring the Remarkable Chemotherapeutic Potential of Polyphenolic Antioxidants in Battling Various Forms of Cancer
ota Yousuf Mohammed Plant-derived compounds, specifically antioxidants, have played an important role in scavenging the free radicals present under diseased conditions. The persistent generation of free radicals in the body leads to inflammation and can result in even more severe diseases such as cancer. Notably, the antioxidant potential of various plant-derived compounds prevents and deregulates the formation of radicals by initiating their decomposition. There is a vast literature demonstrating antioxidant compounds’ anti-inflammatory, anti-diabetic, and anti-cancer potential. This review describes t...
Source: Molecules - April 14, 2023 Category: Chemistry Authors: Mohammad Imran Areeba Insaf Nazeer Hasan Vrushabh V. Sugandhi Deumaya Shrestha Keshav Raj Paudel Saurav Kumar Jha Philip M. Hansbro Kamal Dua Hari Prasad Devkota Yousuf Mohammed Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3424: Fusarium-Derived Secondary Metabolites with Antimicrobial Effects
uawei Zhang Fungal microbes are important in the creation of new drugs, given their unique genetic and metabolic diversity. As one of the most commonly found fungi in nature, Fusarium spp. has been well regarded as a prolific source of secondary metabolites (SMs) with diverse chemical structures and a broad spectrum of biological properties. However, little information is available concerning their derived SMs with antimicrobial effects. By extensive literature search and data analysis, as many as 185 antimicrobial natural products as SMs had been discovered from Fusarium strains by the end of 2022. This review first p...
Source: Molecules - April 13, 2023 Category: Chemistry Authors: Meijie Xu Ziwei Huang Wangjie Zhu Yuanyuan Liu Xuelian Bai Huawei Zhang Tags: Review Source Type: research

Molecules, Vol. 28, Pages 3420: Virtual Screening Strategy to Identify Retinoic Acid-Related Orphan Receptor & gamma;t Modulators
Molecules, Vol. 28, Pages 3420: Virtual Screening Strategy to Identify Retinoic Acid-Related Orphan Receptor γt Modulators Molecules doi: 10.3390/molecules28083420 Authors: Elmeri M. Jokinen Miika Niemeläinen Sami T. Kurkinen Jukka V. Lehtonen Sakari Lätti Pekka A. Postila Olli T. Pentikäinen Sanna P. Niinivehmas Molecular docking is a key method used in virtual screening (VS) campaigns to identify small-molecule ligands for drug discovery targets. While docking provides a tangible way to understand and predict the protein-ligand complex formation, the docking algorithms are often unable ...
Source: Molecules - April 13, 2023 Category: Chemistry Authors: Elmeri M. Jokinen Miika Niemel äinen Sami T. Kurkinen Jukka V. Lehtonen Sakari L ätti Pekka A. Postila Olli T. Pentik äinen Sanna P. Niinivehmas Tags: Article Source Type: research