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Infectious Disease: COVID-19

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Total 240369 results found since Jan 2013.

Transcriptomic Analysis in Renal Cell Carcinoma and COVID-19 patients
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):156-162. doi: 10.14715/cmb/2023.69.8.24.ABSTRACTCOVID-19 pandemic poses a heavy risk upon global public health. The disease's severity and infection rate are high, especially among cancer patients. The current research was conducted to identify the most common biological pathways and how far they are associated with COVID-19 infection and clear cell renal cell carcinoma. In the current study, the authors analyzed the differentially expressed genes from the experimental and control groups with the help of the GEO2R tool. The study analyzed the protein-protein interactions th...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Maha Abdulla Alwaili Source Type: research

Occurrence, formation, and proteins perturbation of disinfection byproducts in indoor air resulting from chlorine disinfection
This study highlights the potential secondary biological risk caused by intensive DBPs generated from chlorination and draws our attention to the potential environmental factors leading to chronic respiratory disease.PMID:37716567 | DOI:10.1016/j.chemosphere.2023.140182
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Yangwei Xiang Huan Xu Source Type: research

Recombinant Antibodies to Face SARS-CoV-2 Syndemic
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):24-27. doi: 10.14715/cmb/2023.69.7.4.ABSTRACTIn recent years, increasing interest has been paid to using antibody-based therapies for clinical applications. However, it is unclear whether recombinant antibodies can be combined with other scientific approaches to generate innovative solutions for mitigating severe acute respiratory syndrome coronavirus 2. In this context, the increase in this virus transmission, the number of infected people, and the interaction between social and biological processes have led to a syndemic, exacerbating the public health problem. Here, we a...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Maykel Gonz ález Torres Gerardo Leyva G ómez Mar ía Luisa Del Prado-Audelo Hern án Cortés Jonathan J Maga ña Source Type: research

Tele-Neuropsychology: From Science to Policy to Practice
CONCLUSIONS: More studies of the reliability and validity of in-home tele-np-t using randomization methodology are necessary to support inclusion of tele-np-t codes on the CMS and CPT telehealth lists, and subsequently, the integration and delivery of in-home tele-np-t services across providers and institutions. These actions are needed to maintain equitable reimbursement of in-home tele-np-t services and address the widespread disparities in healthcare access.PMID:37715508 | DOI:10.1093/arclin/acad066
Source: Archives of Clinical Neuropsychology - September 16, 2023 Category: Psychiatry & Psychology Authors: Scott A Sperling Shawn K Acheson Joshua Fox-Fuller Mary K Colvin Lana Harder C Munro Cullum John J Randolph Kirstine R Carter Patricia Espe-Pfeifer Laura H Lacritz Peter A Arnett Stephen R Gillaspy Source Type: research

Transcriptomic Analysis in Renal Cell Carcinoma and COVID-19 patients
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):156-162. doi: 10.14715/cmb/2023.69.8.24.ABSTRACTCOVID-19 pandemic poses a heavy risk upon global public health. The disease's severity and infection rate are high, especially among cancer patients. The current research was conducted to identify the most common biological pathways and how far they are associated with COVID-19 infection and clear cell renal cell carcinoma. In the current study, the authors analyzed the differentially expressed genes from the experimental and control groups with the help of the GEO2R tool. The study analyzed the protein-protein interactions th...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Maha Abdulla Alwaili Source Type: research

Review of the impact of the FDA's Fast Track Designation on biotechnology companies' share prices
This study examines the effect of the FDA's Fast Track Designation (FTD) on biotech company share prices. Using an event-study approach on 25 FTD announcements between June 2019 and June 2020, notable short- and long-term share price hikes were observed, with a 5-day cumulative average abnormal returns of 21.59%, 30-day at 38.34%, 1-year at 76.64% and 3-year at 111.37% against the XBI benchmark. These surges surpass prior research findings, indicating stronger investor reactions. The role of the COVID-19 pandemic as a confounder is discussed. Although the sample size is limited, the results offer valuable insights for inve...
Source: Drug Discovery Today - September 16, 2023 Category: Drugs & Pharmacology Authors: Joab Williamson Alexander James Spicer Source Type: research

Occurrence, formation, and proteins perturbation of disinfection byproducts in indoor air resulting from chlorine disinfection
This study highlights the potential secondary biological risk caused by intensive DBPs generated from chlorination and draws our attention to the potential environmental factors leading to chronic respiratory disease.PMID:37716567 | DOI:10.1016/j.chemosphere.2023.140182
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Yangwei Xiang Huan Xu Source Type: research

Transcriptomic Analysis in Renal Cell Carcinoma and COVID-19 patients
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):156-162. doi: 10.14715/cmb/2023.69.8.24.ABSTRACTCOVID-19 pandemic poses a heavy risk upon global public health. The disease's severity and infection rate are high, especially among cancer patients. The current research was conducted to identify the most common biological pathways and how far they are associated with COVID-19 infection and clear cell renal cell carcinoma. In the current study, the authors analyzed the differentially expressed genes from the experimental and control groups with the help of the GEO2R tool. The study analyzed the protein-protein interactions th...
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Maha Abdulla Alwaili Source Type: research

Renewal equations for delayed population behaviour adaptation coupled with disease transmission dynamics: A mechanism for multiple waves of emerging infections
Math Biosci. 2023 Sep 14:109068. doi: 10.1016/j.mbs.2023.109068. Online ahead of print.ABSTRACTThere are many plausible reasons for recurrent outbreaks of emerging infectious diseases. In this paper, we develop a mathematical model to illustrate how population behavioural adaption and adaptation implementation delay, in response to the perceived infection risk, can lead to recurrent outbreak patterns. We consider the early phase of an infection outbreak when herd immunity is not reached, pathogen mutation is not considered, and seasonality is ruled out as a major contributor. We derive a transmission dynamics model coupled...
Source: Mathematical Biosciences - September 16, 2023 Category: Statistics Authors: Xue Zhang Francesca Scarabel Kumar Murty Jianhong Wu Source Type: research

Advanced bibliometric analysis on water, energy, food, and environmental nexus (WEFEN)
This article investigates research within the field of the quadruple nexus. Data from Scopus documents, with the keywords "water, energy, food, and environment" from 2011 to 2022, were processed and analyzed. Further research revealed that scientific exploration of the water-energy-food-environment relationship is rapidly expanding. The Scopus database was used to extract information about countries, institutions, highly cited publications, keywords, hot topics, and future research trends for this study. Additionally, the VOSviewer bibliometric software was employed to evaluate the scientific citations in this article. The...
Source: Environmental Science and Pollution Research International - September 16, 2023 Category: Environmental Health Authors: Armin Tayefeh Mahmoud Abdous Rahim Zahedi Alireza Aslani Mohammad Mahdi Zolfagharzadeh Source Type: research

Ethical Requirements for Human Challenge Studies: A Systematic Review of Reasons
Clin Pharmacol Ther. 2023 Sep 16. doi: 10.1002/cpt.3054. Online ahead of print.ABSTRACTHuman challenge studies (HCS) are controlled clinical trials in which participants are deliberately infected with a pathogen. Such trials are being developed for an increasing number of diseases. Partly as a result of the COVID-19 pandemic, there has been a recent ethical debate about the reasons for and against HCS in general, or rather, about the requirements that individual HCS must fulfill to be ethically acceptable. A systematic review was conducted to categorize and summarize such requirements and the reasons given for them. Ethics...
Source: Clinical Pharmacology and Therapeutics - September 16, 2023 Category: Drugs & Pharmacology Authors: Matthias Katzer Sabine Salloch Christoph Schindler Marcel Mertz Source Type: research

COVID-19 vaccine effectiveness against hospitalizations in Paraguay, May 2021-April 2022: A test-negative design
CONCLUSIONS: This study contributes to our understanding of COVID-19 VE in Latin America and to global understanding of vaccines that have not been widely used in North America and Europe. VE estimates from Paraguay can parameterize models to estimate the impact of the national COVID-19 vaccination campaign in Paraguay and similar settings.PMID:37716830 | DOI:10.1016/j.vaccine.2023.09.015
Source: Vaccine - September 16, 2023 Category: Allergy & Immunology Authors: Sandra Irala Sarah Hamid Elena Penayo Fabiana Michel Paula Couto Cynthia Vazquez Mar ía José Ortega Chavely Dom ínguez Silvia Battaglia Marta Von Horoch Romeo Montoya Guillermo Sequera Francisco Nogareda Source Type: research

Recombinant Antibodies to Face SARS-CoV-2 Syndemic
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):24-27. doi: 10.14715/cmb/2023.69.7.4.ABSTRACTIn recent years, increasing interest has been paid to using antibody-based therapies for clinical applications. However, it is unclear whether recombinant antibodies can be combined with other scientific approaches to generate innovative solutions for mitigating severe acute respiratory syndrome coronavirus 2. In this context, the increase in this virus transmission, the number of infected people, and the interaction between social and biological processes have led to a syndemic, exacerbating the public health problem. Here, we a...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Maykel Gonz ález Torres Gerardo Leyva G ómez Mar ía Luisa Del Prado-Audelo Hern án Cortés Jonathan J Maga ña Source Type: research

Omega-3 polyunsaturated fatty acids and the psychiatric post-acute sequelae of COVID-19: A one-year retrospective cohort analysis of 33,908 patients
CONCLUSION: Omega-3 PUFAs may require re-evaluation as a preventive strategy against adverse mental health outcomes post-COVID-19 in placebo-controlled clinical trials.PMID:37716377 | DOI:10.1016/j.bbi.2023.09.008
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Ting-Hui Liu Chung-Han Ho Daniel Tzu-Li Chen Jheng-Yan Wu Po-Yu Huang Chih-Cheng Lai Kuang-Yang Hsieh Kuan-Pin Su Source Type: research

Demographic and Geographic Characterization of Excess Mortality During the COVID-19 Pandemic in Baltimore City, MD, March 2020 - March 2021
Am J Epidemiol. 2023 Sep 15:kwad186. doi: 10.1093/aje/kwad186. Online ahead of print.ABSTRACTEstimates of excess mortality can provide insight into direct and indirect impacts of the COVID-19 pandemic beyond deaths specifically attributed to COVID-19. We analyzed death certificate data from Baltimore City, Maryland from March 1, 2020 to March 31, 2021 and found that 1,725 individuals (95% confidence interval, 1,495-1,954) died in excess of what was expected from all-cause mortality trends in 2016-2019. 1,050 (61%) excess deaths were attributed to COVID-19. Observed mortality was 23-32% higher than expected among individual...
Source: Am J Epidemiol - September 16, 2023 Category: Epidemiology Authors: Kyle T Aune Kyra H Grantz Neia Prata Menezes Katherine O Robsky Emily S Gurley Melissa A Marx Darcy F Phelan-Emrick Source Type: research