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Total 969764 results found since Jan 2013.
Distinguishing among multiple sclerosis fallers, near-fallers and non-fallers
Conclusion Near-falls occur commonly in individuals with MS; near-fallers and fallers reported similar circumstances surrounding fall events and demonstrated similar performance on standard timed walking tests. Clinicians monitoring individuals with MS should consider evaluation of the circumstances surrounding falls in combination with quantitative walking measures to improve determination of fall risk and appropriate rehabilitation interventions.
Source: Multiple Sclerosis and Related Disorders - December 16, 2017 Category: Neurology Source Type: research
Coping strategies and quality of life in Mexican Multiple Sclerosis patients: physical, psychological and social factors relationship
CONCLUSION The use of positive coping strategies in conjunction with a suitable psycho-social environment and good physical health result in a better perception of QoL in Mexican patients living with MS. Still, the negative factors are ineffectively diagnosed and hence generally under treated in medical MS monitoring. An interdisciplinary evaluation will provide the adequate tools to confront the diagnosis and the uncertainty of multiple sclerosis evolution, benefiting the QoL of Mexican patients with MS.
Source: Multiple Sclerosis and Related Disorders - June 26, 2018 Category: Neurology Source Type: research
Treatment retention on fingolimod compared with injectable multiple sclerosis therapies in African–American patients: A subgroup analysis of a randomized phase 4 study
Conclusion: In PREFERMS, fingolimod was associated with better treatment retention than iDMTs in African–American patients. Optimal outcomes in the management of multiple sclerosis depend on good persistence with treatment, and this is particularly important in patient populations at increased risk of a rapidly progressing disease course.Trial Registration: NCT01623596.Funding: Novartis Pharmaceuticals Corporation.
Source: Multiple Sclerosis and Related Disorders - July 11, 2018 Category: Neurology Source Type: research
Treatment retention on fingolimod compared with injectable multiple sclerosis therapies in African-American patients: A subgroup analysis of a randomized phase 4 study
ConclusionIn PREFERMS, fingolimod was associated with better treatment retention than iDMTs in African-American patients. Optimal outcomes in the management of multiple sclerosis depend on good persistence with treatment, and this is particularly important in patient populations at increased risk of a rapidly progressing disease course.
Source: Multiple Sclerosis and Related Disorders - July 20, 2018 Category: Neurology Source Type: research
Sex ratio of multiple sclerosis in the National Swedish MS Register (SMSreg)
Conclusion:
There is no evidence for an increasing women-to-men ratio with time amongst Swedish multiple sclerosis patients.
Source: Multiple Sclerosis - January 9, 2013 Category: Neurology Authors: Bostrom, I., Stawiarz, L., Landtblom, A.-M. Tags: Research Papers Source Type: research
Multiple Sclerosis Foundation Brighter Tomorrow Grant
Each year the Multiple Sclerosis Foundation makes dreams come true for individuals with multiple sclerosis across the country through the Brighter Tomorrow grant. The goal of the grant is provide individuals with MS with goods or services (valued at up to $1000.00 per recipient) to improve their quality of life by enhancing safety, self-sufficiency, comfort, or well-being. Recipients of the Multiple Sclerosis Foundation's Brighter Tomorrow grant have received appliances, televisions, furniture, hobby supplies, retreats, and various home modifications. To qualify, a person must be 18 years of age or older and d...
Source: ScanGrants feed - January 31, 2013 Category: Research Authors: Multiple Sclerosis Foundation Source Type: funding
Antibodies Against Gangliosides in the Serum of Patients Suffering from Multiple Sclerosis Compared with Healthy Individuals (P03.243)
CONCLUSIONS: Our results are indicative of a significant role of anti-GM1 and anti-GD1b IgM antibodies in MS. Further investigation should be established in order to provide insights on the potential autoantigenic role and the pattern of serum antibody reactivity to gangliosides in multiple sclerosis.Supported by: Greek Foundation for National Scholarships.Disclosure: Dr. Koutsouraki has nothing to disclose. Dr. Hatzifilippou has nothing to disclose. Dr. Kalatha has nothing to disclose. Dr. Antoniadou has nothing to disclose. Dr. Baloyannis has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Koutsouraki, E., Hatzifilippou, E., Kalatha, T., Antoniadou, E., Baloyannis, S. Tags: P03 Multiple Sclerosis: Disease Biomarkers Source Type: research
Radiologically isolated syndrome - incidental magnetic resonance imaging findings suggestive of multiple sclerosis, a systematic review
With increasing availability of magnetic resonance imaging (MRI), there is also an increase in incidental abnormal findings. MRI findings suggestive of multiple sclerosis in persons without typical multiple sclerosis symptoms and with normal neurological findings are defined as radiologically isolated syndrome (RIS). Half of the persons with RIS have their initial MRI because of headache, and some have a subclinical cognitive impairment similar to that seen in multiple sclerosis. Radiological measurements also show a similarity between RIS and multiple sclerosis. Approximately two-thirds of persons with RIS show radiologic...
Source: Multiple Sclerosis - February 20, 2013 Category: Neurology Authors: Granberg, T., Martola, J., Kristoffersen-Wiberg, M., Aspelin, P., Fredrikson, S. Tags: Review Source Type: research
Organ Donation for Transplant with Multiple Sclerosis
A recent blog post about the plight of Sherri Muzher and her struggle to be of use beyond her life by donating her organs (while still alive; thus hastening her death) spared a lively conversation in the comments section. One of the questions and concerns tables was whether or not Ms Muzher’s organs and tissue would even be acceptable as transplant options for people in need.
As I often do when we come upon a medical question in our discussions, I reached out to several experts for clarification. In this case is was Dr James Bowen, M.D. of Swedish Neuroscience Institute. Dr Bowen is not only a respected researcher ...
Source: Life with MS - August 21, 2013 Category: Other Conditions Authors: Trevis Gleason Tags: MS multiple sclerosis clinical trials comments MS and family MS doctors MS in the news multiple sclerosis clinical trials multiple sclerosis cure research Source Type: blogs
Multiple Sclerosis; A New Global Database
First the bad news: It looks like the incidence of multiple sclerosis has jumped by about 10% since 2008.
The good news: At least someone is keeping track… and we have access to their data.
The Multiple Sclerosis International Federation (MSIF) conducted a global study of MS in 2013 and the information has just been released on the website AtlasOfMS.org
I’ve only scratched a bit of the surface of this site, but it seems to have loads of information in this site for the digging. Not that much of it will be stuff that the everyday Joe or Jane will need to get on with the business of living with MS, but still. If kn...
Source: Life with MS - October 4, 2013 Category: Other Conditions Authors: Trevis Gleason Tags: MS multiple sclerosis community life with MS MS in the news research world MS day Source Type: blogs
Multiple Sclerosis Exacerbation Presenting as Stress Cardiomyopathy (P6.162)
Conclusions: Stress cardiomyopathy is increasingly suspected to be neurogenic in etiology. This case not only supports this theory, but also reports multiple sclerosis to be a potential cause of neurologic dysfunction leading to this cardiac phenomenon. In addition, it fortifies the theory that bilateral medullary lesions are required for many instances of autonomic dysfunction.Disclosure: Dr. Webb has nothing to disclose. Dr. Reyna has nothing to disclose. Dr. Blair has nothing to disclose. Dr. Foreman has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Webb, T., Reyna, T., Blair, R., Foreman, R. Tags: Multiple Sclerosis Symptoms and Comorbidities Source Type: research
Longitudinal Evaluation of Cognitive Functioning in Pediatric Multiple Sclerosis (MS): Report from the U.S. Pediatric Multiple Sclerosis Network (S33.004)
CONCLUSIONS: Findings suggest that over short time frames, stable or even improved performances on measures of cognitive ability can occur in pediatric MS. Rather than leading to decline, pediatric MS may instead adversely affect cognitive functioning by interfering with expected age-appropriate gains.Study Supported by: The Lourie Foundation, Inc., National Multiple Sclerosis Society (10020073405), NIH R01N5071463, and the Slomo and Cindy Silvian Foundation.Disclosure: Dr. Krupp has received personal compensation for activities with Teva Neurosciences, Biogen Idec, EMD Serono, Betaseron/Bayer Healthcare Pharmaceuticals, G...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Krupp, L., Charvet, L., O'Donnell, E., Cleary, R., Serafin, D., Parrish, J., Julian, L., Baruch, N., Belman, A., Benedict, R., Chitnis, T., Ness, J., Rodriguez, M., Waubant, E., Weinstock-Guttman, B. Tags: Cognition Fatigue in Multiple Sclerosis Source Type: research
A Multivariate Risk Calculator for Multiple Sclerosis and Study of an Endophenotype in Siblings of People with Multiple Sclerosis (S34.002)
CONCLUSIONS:This risk score has the best AUC described to date. Siblings have an intermediate risk score, in keeping with their "at risk" position. Siblings with a high risk score have increased IL17 production, a potential endophenotypic marker.Study Supported by:Multiple Sclerosis Society of Great Britain and Northern IrelandDisclosure: Dr. Dobson has nothing to disclose. Dr. Topping has nothing to disclose. Dr. Chard holds stock and/or stock options in GlaxoSmithKline, Inc. Dr. Chard has received research support from the Multiple Sclerosis Society of Great Britain and Northern Ireland. Dr. Schmierer has received person...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Dobson, R., Topping, J., Chard, D., Schmierer, K., Smith, P., Ramagopalan, S., Giovannoni, G. Tags: MS and CNS Inflammatory Disease: Risk Factors for Multiple Sclerosis Disease and Course Source Type: research
Multiple Sclerosis Foundation Brighter Tomorrow Grant
Each year the Multiple Sclerosis Foundation makes dreams come true for individuals with multiple sclerosis across the country through the Brighter Tomorrow grant. The goal of the grant is provide individuals with MS with goods or services (valued at up to $1000.00 per recipient) to improve their quality of life by enhancing safety, self-sufficiency, comfort, or well-being. Recipients of the Multiple Sclerosis Foundation's Brighter Tomorrow grant have received appliances, televisions, furniture, hobby supplies, retreats, and various home modifications. To qualify, a person must be 18 years of age or older and d...
Source: ScanGrants feed - May 5, 2014 Category: Research Authors: Multiple Sclerosis Foundation Source Type: funding
Impact of prior treatment status and reasons for discontinuation on the efficacy and safety of fingolimod: Subgroup analyses of the Fingolimod Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis (FREEDOMS) study
Conclusions Fingolimod demonstrated similar efficacy in relapsing multiple sclerosis patients regardless of prior treatment history. Clinicaltrials.gov identifier: NCT00289978.
Source: Multiple Sclerosis and Related Disorders - November 11, 2014 Category: Neurology Source Type: research
