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Total 1864 results found since Jan 2013.

Our patients’ stories: fixing Brody’s omphalocele
By Maureen Simoncini Brody When I was 18 weeks pregnant my husband, Kenny, and I went in for a routine ultrasound. We were excited to find out if I was carrying a boy or a girl, but we found out much more than that. The ultrasound revealed that I was having a boy, but he would be born with a serious medical condition called an omphalocele. (It’s a birth defect where the baby’s intestine or other organs stick out of the belly button. In many cases only a thin layer of tissue covers the intestines.) Once it was established that our baby had an omphalocele, we were transferred to a doctor at our local hospita...
Source: Thrive, Children's Hospital Boston - March 22, 2013 Category: Pediatrics Authors: Guest Blogger Tags: All posts Diseases & conditions Our patients’ stories omphalocele our patients' stories surgery Terry Buchmiller Source Type: news

Stem cells and birth defects: Could gastroschisis be treated in utero?
Although Gianna was treated surgically, Dario Fauza, MD, hopes to someday use stem cells from the amniotic fluid, multiplied and returned to the womb, to naturally heal gastroschisis and other birth defects. (Courtesy Danielle DeCarlo) Six-year-old Gianna DiCarlo is an active dancer and gymnast. Though she’s a healthy eater now, Gianna’s stomach bears a long scar, a remnant of three surgeries she underwent as an infant. She was born with gastroschisis, a striking birth defect in which the abdominal wall doesn’t seal fully during fetal development. As a result, her intestines developed outside her body. Sh...
Source: Thrive, Children's Hospital Boston - July 13, 2016 Category: Pediatrics Authors: Nancy Fliesler Tags: Our Patients’ Stories Research and Innovation gastroschisis Source Type: news

Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates - United States, 2006-2015 | MMWR
During 2011-2015, gastroschisis prevalence was 4.5 per 10,000 live births, which was 10% higher than the prevalence during 2006-2010. An ecologic analysis found a higher prevalence of gastroschisis where opioid prescriptions rates were high, supporting epidemiologic data suggesting an association between opioid use during pregnancy and gastroschisis.
Source: CDC Morbidity and Mortality Weekly Report - January 18, 2019 Category: American Health Tags: Gastroschisis MMWR Morbidity & Mortality Weekly Report Opioids Source Type: news

Gestational Outcomes of Pregnancies with Prenatally Detected Gastroschisis and Omphalocele.
CONCLUSION: Additional genetic disorders are more frequent in those with omphalocele cases, and they are more frequently terminated during gestation that the gastroschisis fetuses. PMID: 30892123 [PubMed - as supplied by publisher]
Source: Fetal and Pediatric Pathology - March 22, 2019 Category: Pathology Tags: Fetal Pediatr Pathol Source Type: research

Is anemia frequently recognized in gastroschisis compared to omphalocele? A multicenter retrospective study in southern Japan
ConclusionsGastroschisis may carry an increased risk of developing anemia compared with omphalocele due to the difference of direct intestinal exposure of amnion fluid in utero.
Source: Pediatric Surgery International - June 28, 2022 Category: Surgery Source Type: research

Anomalies associated with gastroschisis and omphalocele: Analysis of 2825 cases from the Texas Birth Defects Registry
Conclusions: Gastroschisis as well as omphalocele has significant associated anomalies that are important to appreciate during pre- and postnatal management.
Source: Journal of Pediatric Surgery - November 20, 2013 Category: Surgery Authors: Bonna Benjamin, Golder N. Wilson Tags: Original Articles Source Type: research

Registry analysis supports different mechanisms for gastroschisis and omphalocele within shared developmental fields
Nine thousand two hundred eighty abnormalities associated with 2,943 abdominal wall defects (AWD) encoded from 1999 to 2008 by the Texas Birth Defects Registry (TBDR) were classified and analyzed for mechanism, beginning with 1,831 gastroschisis cases, 774 (41%) with 2,368 associated anomalies (AA) and 814 of omphalocele, 727 (89%) with 4,092 AA. Typical AA profiles for Trisomy 18 (23% of omphalocele cases) and Beckwith–Wiedemann syndrome (15%) validated registry AA descriptors, chromosome disorders surprisingly accounting for 24% of known conditions with gastroschisis followed by expected amniotic band (ADAM) complex (2...
Source: American Journal of Medical Genetics Part A - July 2, 2015 Category: Genetics & Stem Cells Authors: Bonna Benjamin, Golder N. Wilson Tags: Research Article Source Type: research

Prenatal examination and postmortem findings in fetuses with gastroschisis and omphalocele
ConclusionThis study shows that the correlation between prenatal ultrasound findings and postmortem examination is good and has improved over time. Comparing full agreement during the first 10 years with the last 15 years showed an improvement (p = 0.05) for fetuses with omphalocele. This article is protected by copyright. All rights reserved.
Source: Prenatal Diagnosis - March 7, 2014 Category: Perinatology & Neonatology Authors: Tone Mæland Faugstad, Anne Brantberg, Harm‐Gerd K. Blaas, Christina Vogt Tags: Original Article Source Type: research

Effectiveness of Wharton’s jelly stem cells in gastroschisis repair using the inner surface of the umbilical cord as a patch: long-term results
Conclusion: This paper describes the effect of the local application of WJ – that is, mesenchymal stromal cells derived from the inner surface of the umbilical stump – and its influence on the healing process of the birth defect and wound.
Source: Annals of Pediatric Surgery - July 1, 2015 Category: Surgery Tags: Original Articles Source Type: research

Omphalocele and gastroschisis trends among states with vs without 20-week abortion bans from 2012-2018
Prior to recent legislature changes, many states enacted 20-week abortion bans. As related laws are implemented, understanding associated impacts may help guide future care. Gastroschisis and omphalocele diagnoses are often diagnosed at 20-week anatomy ultrasounds. Omphalocele is more often associated with other anomalies and carries a greater mortality rate compared to gastroschisis. We sought to examine trends in rates of gastroschisis and omphalocele diagnoses between states with and without 20-week abortion bans in the US during 2012-2018.
Source: American Journal of Obstetrics and Gynecology - January 1, 2023 Category: OBGYN Authors: Rachel Egan, Uma Doshi, Sarina R. Chaiken, Bharti Garg, Aaron B. Caughey Tags: Poster Session IV Source Type: research

Not gastroschisis or omphalocele or anything in between: a novel congenital abdominal wall defect
AbstractCongenital abdominal wall defects occur when normal embryonic development is interrupted and most commonly results in gastroschisis or omphalocele. Other entities, such as ruptured omphalocele, vanishing gastroschisis, and patent omphalomesenteric ducts with prolapse, have also been described and can create a confusing picture. This case of a newborn with a midline abdominal defect and a mass that was intestine-like and arose from the bowel cannot be classified, and no similar reports were found. This suggests a previously undescribed abdominal wall defect with an aberrant colonic appendage.
Source: Pediatric Surgery International - March 6, 2017 Category: Surgery Source Type: research

Coexisting Gastrointestinal and Hepatobiliary Tract Anomalies in Omphalocele and Gastroschisis: A Twenty-Year Experience in a Single Tertiary Medical Center
This study aimed to investigate the demographic characteristics, coexisting congenital gastrointestinal and hepatobiliary tract anomalies, hospital course, and outcomes of patients with gastroschisis and omphalocele.
Source: Pediatrics and Neonatology - May 18, 2022 Category: Perinatology & Neonatology Authors: Chen-Chen Wen, Tien-Chueh Kuo, Hung-Chang Lee, Chun-Yan Yeung, Wai-Tao Chan, Chuen-Bin Jiang, Jin-Cherng Sheu, Nien-Lu Wang, Chyong-Hsin Hsu, Shu-Chao Weng, Yufeng Jane Tseng Tags: Original Article Source Type: research

Gastroschisis in one twin neonate with extracorporeal liver
We report a rare case of gastroschisis with extracorporeal liver suspected on late first trimester ultrasound and confirmed with second trimester ultrasound and magnetic resonance imaging in one fetus in a twin pregnancy. Liver herniation is common in omphalocele, a membrane-covered abdominal wall defect associated with other congenital anomalies. However, it is highly uncommon in gastroschisis, an uncovered abdominal wall defect aside of the cord insertion. Presence of liver herniation complicates prenatal differentiation between omphalocele and gastroschisis. The twins were born at 31 weeks' gestation due to preterm labo...
Source: Baylor University Medical Center Proceedings - November 4, 2021 Category: Universities & Medical Training Authors: Kayla Hudson Krista L Birkemeier Hayden Stagg Steven R Allen Source Type: research