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Total 2868 results found since Jan 2013.

Molecules, Vol. 28, Pages 6750: Spin-Label Electron Paramagnetic Resonance Spectroscopy Reveals Effects of Wastewater Filter Membrane Coated with Titanium Dioxide Nanoparticles on Bovine Serum Albumin
r Páli The accumulation of proteins in filter membranes limits the efficiency of filtering technologies for cleaning wastewater. Efforts are ongoing to coat commercial filters with different materials (such as titanium dioxide, TiO2) to reduce the fouling of the membrane. Beyond monitoring the desired effect of the retention of biomolecules, it is necessary to understand what the biophysical changes are in water-soluble proteins caused by their interaction with the new coated filter membranes, an aspect that has received little attention so far. Using spin-label electron paramagnetic resonance (EPR), aided with native...
Source: Molecules - September 22, 2023 Category: Chemistry Authors: Krisztina Seb ők-Nagy Zolt án Kóta Andr ás Kincses Ákos Ferenc Fazekas Andr ás Dér Zsuzsanna L ászló Tibor P áli Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6749: Development and Evaluation of Topical Zinc Oxide Nanogels Formulation Using Dendrobium anosmum and Its Effect on Acne Vulgaris
In this study, biogenically synthesized zinc oxide nanoparticles using Dendrobium anosum are used as a reducing and capping agent for topical anti-acne nanogels, and the antimicrobial effect of the nanogel is assessed on Cutibacterium acne and Staphylococcus aureus. Dendrobium anosmum leaf extract was examined for the presence of secondary metabolites and its total amount of phenolic and flavonoid content was determined. Both the biogenically and chemogenic-synthesized zinc oxide nanoparticles were compared using UV-Visible spectrophotometer, FE-SEM, XRD, and FTIR. To produce the topical nanogel, the biogenic and chemogeni...
Source: Molecules - September 22, 2023 Category: Chemistry Authors: Yu Yang Tan Ling Shing Wong Kar Lin Nyam Kitiyaporn Wittayanarakul Nurliyana Ahmad Zawawi Kavitha Rajendran Sinovassane Djearamane Anto Cordelia Tanislaus Antony Dhanapal Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6763: Diabetes Management by Fourth-Generation Glucose Sensors Based on Lemon-Extract-Supported CuO Nanoporous Materials
n Diabetes is a major worldwide health issue, impacting millions of people around the globe and putting pressure on healthcare systems. Accurate detection of glucose is critical for efficient diabetes care, because it allows for prompt action to control blood sugar levels and avoid problems. Reliable glucose-sensing devices provide individuals with real-time information, allowing them to make more educated food, medicine, and lifestyle decisions. The progress of glucose sensing holds the key to increasing the quality of life for diabetics and lowering the burden of this prevalent condition. The present investigation ad...
Source: Molecules - September 22, 2023 Category: Chemistry Authors: Israr U. Hassan Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6730: GeO2 Nanoparticles Decorated in Amorphous Carbon Nanofiber Framework as Highly Reversible Lithium Storage Anode
n Sun Xiaolei Sun Germanium oxide (GeO2) is a high theoretical capacity electrode material due to its alloying and conversion reaction. However, the actual cycling capacity is rather poor on account of suffering low electron/ion conductivity, enormous volume change and agglomeration in the repeated lithiation/delithiation process, which renders quite a low reversible electrochemical lithium storage reaction. In this work, highly amorphous GeO2 particles are uniformly distributed in the carbon nanofiber framework, and the amorphous carbon nanofiber not only improves the conduction and buffers the volume changes but al...
Source: Molecules - September 21, 2023 Category: Chemistry Authors: Wenhe Xie Congcong Liu Chen Hu Yuanxiao Ma Xuefeng Li Qian Wang Zhe An Shenghong Liu Haibin Sun Xiaolei Sun Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6709: Facile Synthesis of Co Nanoparticles Embedded in N-Doped Carbon Nanotubes/Graphitic Nanosheets as Bifunctional Electrocatalysts for Electrocatalytic Water Splitting
ang Zhipeng Xie Developing robust and cost-effective electrocatalysts to boost hydrogen evolution reactions (HERs) and oxygen evolution reactions (OERs) is crucially important to electrocatalytic water splitting. Herein, bifunctional electrocatalysts, by coupling Co nanoparticles and N-doped carbon nanotubes/graphitic nanosheets (Co@NCNTs/NG), were successfully synthesized via facile high-temperature pyrolysis and evaluated for water splitting. The morphology and particle size of products were influenced by the precursor type of the cobalt source (cobalt oxide or cobalt nitrate). The pyrolysis product prepared using ...
Source: Molecules - September 20, 2023 Category: Chemistry Authors: Wei Yang Han Li Pengzhang Li Linhua Xie Yumin Liu Zhenbao Cao Chuanjin Tian Chang-An Wang Zhipeng Xie Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6696: Antiviral Effect of 5 & prime;-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection
Molecules, Vol. 28, Pages 6696: Antiviral Effect of 5′-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection Molecules doi: 10.3390/molecules28186696 Authors: Amanda Resende Tucci Raquel Mello da Rosa Alice Santos Rosa Otávio Augusto Chaves Vivian Neuza Santos Ferreira Thamara Kelcya Fonseca Oliveira Daniel Dias Coutinho Souza Nathalia Roberto Resende Borba Luciano Dornelles Nayra Salazar Rocha João Candido Pilar Mayer João B. Teixeira da Rocha Oscar Endrigo D. Rodrigues Milene Dias Miranda The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits t...
Source: Molecules - September 19, 2023 Category: Chemistry Authors: Amanda Resende Tucci Raquel Mello da Rosa Alice Santos Rosa Ot ávio Augusto Chaves Vivian Neuza Santos Ferreira Thamara Kelcya Fonseca Oliveira Daniel Dias Coutinho Souza Nathalia Roberto Resende Borba Luciano Dornelles Nayra Salazar Rocha Jo ão Candido Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6687: Copper and Copper-Based Nanoparticles in Medicine & mdash;Perspectives and Challenges
This article aims to provide contemporary insights into the perspectives and challenges regarding the use of copper and copper oxide nanoparticles in medicine. It summarises the biomedical potential of copper-based nanoformulations, including the progress of early-stage research, to evaluate and mitigate the potential toxicity of copper nanomaterials. The discussion covers the challenges and prospects of copper-based nanomaterials in the context of their successful clinical translation. The article also addresses safety concerns, emphasizing the need for toxicity assessments of nanomedicines. However, attention is needed t...
Source: Molecules - September 18, 2023 Category: Chemistry Authors: Marta J. Wo źniak-Budych Katarzyna Staszak Maciej Staszak Tags: Review Source Type: research

Molecules, Vol. 28, Pages 6685: Relation between Conventional and Starch-Assisted ASP Injection and Impact of Crystallinity on Flood Formation
This study explores conventional ASP flooding using PT SPR Langgak’s special surfactants, simulating Langgak oilfield conditions in Sumatra, Indonesia. By comparing the outcomes of this flooding technique with that of starch-assisted ASP performed in another study, the benefits of adding starch nanoparticles to flooding are evident. Nano-starch ASP increased oil recovery by 18.37%, 10.76%, and 10.37% for the three configurations investigated in this study. Water flooding preceded ASP flooding, and flooding operations were carried out at 60 °C. This study employed sodium hydroxide (NaOH), sodium ca...
Source: Molecules - September 18, 2023 Category: Chemistry Authors: Hasanain A. Al-Jaber Agus Arsad Sulalit Bandyopadhyay Mohd Zaidi Jaafar Muhammad Tahir Mustafa Jawad Nuhma Abdulmunem R. Abdulmunem Mohammad Yasin Abdulfatah Hajar Alias Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6676: Palladium Nanoparticles Grafted onto Phytochemical Functionalized Biochar: A Sustainable Nanozyme for Colorimetric Sensing of Glucose and Glutathione
A. Patil The devising and development of numerous enzyme mimics, particularly nanoparticles and nanomaterials (nanozymes), have been sparked by the inherent limitations imposed by natural enzymes. Peroxidase is one of the enzymes that is extensively utilized in commercial, medical, and biological applications because of its outstanding substrate selectivity. Herein, we present palladium nanoparticles grafted on Artocarpus heterophyllus (jackfruit) seed-derived biochar (BC-AHE@Pd) as a novel nanozyme to imitate peroxidase activity en route to the rapid and colorimetric detection of H2O2, exploiting o-phenylenediamine a...
Source: Molecules - September 18, 2023 Category: Chemistry Authors: Aakhila Banu Arnet Maria Antony Balappa Somappa Sasidhar Shivaputra A. Patil Siddappa A. Patil Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6666: Dendritogenic Potential of the Ethanol Extract from Lippia alba Leaves in Rat Cortical Neurons
lbarracin A reduced dendritic complexity, especially in regions such as the hippocampus and the prefrontal cortex, has been linked to the pathophysiology of some neuropsychiatric disorders, in which synaptic plasticity and functions such as emotional and cognitive processing are compromised. For this reason, the identification of new therapeutic strategies would be enriched by the search for metabolites that promote structural plasticity. The present study evaluated the dendritogenic potential of the ethanol extract of Lippia alba, an aromatic plant rich in flavonoids and terpenes, which has been widely used in traditi...
Source: Molecules - September 16, 2023 Category: Chemistry Authors: Mar ía Marcela Velásquez Mar ía Claudia Lattig Luis Carlos Chitiva Geison M. Costa Jhon Jairo Sutachan Sonia Luz Albarracin Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6642: Talaromyces sp. Ethyl Acetate Crude Extract as Potential Mosquitocide to Control Culex pipiens quinquefasciatus
In this study, a high-throughput screening method was used to search for potential mosquitocides in the Global Fungal Extract Library (GFEL). We tested the larvicidal activity of 264 fungal ethyl acetate crude extracts against Culex pipiens quinquefasciatus. Nine fungal extracts caused moderate to high mortality rates (>50%), with two fungal extracts (58A7 and 101H12) causing a 100% mortality rate. The lethal concentrations for 50% of the population (LC50) were 44.27 mg/L and 31.90 mg/L, respectively. Fraction 14 had a high mortality rate, with an LC50 value of 12.13 mg/L, and was isolated from 58A7 (Fractions 1...
Source: Molecules - September 15, 2023 Category: Chemistry Authors: Junhui Chen Zhiyong Xu Yangqing Liu Feiying Yang Limei Guan Jian Yang Jianghuai Li Guodong Niu Jun Li Liang Jin Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6604: Could Natural Products Help in the Control of Obesity? Current Insights and Future Perspectives
iawan Bonglee Kim Obesity is a global issue faced by many individuals worldwide. However, no drug has a pronounced effect with few side effects. Green tea, a well-known natural product, shows preventive effects against obesity by decreasing lipogenesis and increasing fat oxidation and antioxidant capacity. In contrast, other natural products are known to contribute to obesity. Relevant articles published on the therapeutic effect of natural products on obesity were retrieved from PubMed, Web of Science, and Scopus. The search was conducted by entering keywords such as “obesity”, &l...
Source: Molecules - September 13, 2023 Category: Chemistry Authors: Jiwon Park Fahrul Nurkolis Hyunji Won Jiye Yang Dayeon Oh Hyunkyung Jo Jinwon Choi Sanghyun Chung Rudy Kurniawan Bonglee Kim Tags: Review Source Type: research

Molecules, Vol. 28, Pages 6595: Insights into the Relationship between the Microstructure and the Catalytic Behavior of Fe2(MoO4)3 during the Ethanolysis of Naomaohu Coal
i Li Lang Liu Ethanolysis is an effective method to depolymerize weak bonds in lignite under mild conditions, which can result in the production of high-value-added chemicals. However, improving ethanolysis yield and regulating its resulting product distribution is a big challenge. Hence, exploiting highly active catalysts is vital. In this work, Fe2(MoO4)3 catalysts with zero-dimensional nanoparticles, one-dimensional (1D) nanorods, two-dimensional (2D) nanosheets, and three-dimensional (3D) nanoflower structures were successfully prepared and applied in the ethanolysis of Naomaohu coal. The results showed that for ...
Source: Molecules - September 13, 2023 Category: Chemistry Authors: Ting Liu Xuesong Sun Yakun Tang Yue Zhang Jingmei Liu Xiaodong Zhou Xiaohui Li Lang Liu Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6559: Immunosensor with Enhanced Electrochemiluminescence Signal Using Platinum Nanoparticles Confined within Nanochannels for Highly Sensitive Detection of Carcinoembryonic Antigen
In this study, an electrochemiluminescence (ECL) immunosensing platform was constructed by enhancing the ECL signal through in situ growth of platinum nanoparticles (PtNPs) in a nanochannel array, which can achieve highly sensitive detection of the tumor marker carcinoembryonic antigen (CEA). An inexpensive and readily available indium tin oxide (ITO) glass electrode was used as the supporting electrode, and a layer of amino-functionalized vertically ordered mesoporous silica film (NH2-VMSF) was grown on its surface using an electrochemically assisted self-assembly method (EASA). The amino groups within the nanochannels se...
Source: Molecules - September 11, 2023 Category: Chemistry Authors: Huihua Zhang Chaoyan Zhang Hui Qu Fengna Xi Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6556: Ginsentide-like Coffeetides Isolated from Coffee Waste Are Cell-Penetrating and Metal-Binding Microproteins
ntony Kam Coffee processing generates a huge amount of waste that contains many natural products. Here, we report the discovery of a panel of novel cell-penetrating and metal ion-binding microproteins designated coffeetide cC1a–c and cL1–6 from the husk of two popular coffee plants, Coffea canephora and Coffea liberica, respectively. Combining sequence determination and a database search, we show that the prototypic coffeetide cC1a is a 37-residue, eight-cysteine microprotein with a hevein-like cysteine motif, but without a chitin-binding domain. NMR determination of cC1a reveals a compact s...
Source: Molecules - September 10, 2023 Category: Chemistry Authors: James P. Tam Jiayi Huang Shining Loo Yimeng Li Antony Kam Tags: Article Source Type: research