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Resolvin D2-GPR18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging
Am J Pathol. 2023 Sep 15:S0002-9440(23)00322-X. doi: 10.1016/j.ajpath.2023.08.011. Online ahead of print.ABSTRACTAging is associated with non-resolving inflammation and tissue dysfunction. Resolvin D2 (RvD2) is a pro-resolving ligand that acts through the G-protein coupled receptor (GPCR) called GPR18. Unbiased RNA sequencing revealed increased Gpr18 expression in macrophages from old mice, and in livers from elderly humans, which was associated with increased steatosis and fibrosis in middle-aged (MA) and old mice. MA mice that lack GPR18 on myeloid cells had exacerbated steatosis and hepatic fibrosis, which was associate...
Source: Am J Pathol - September 17, 2023 Category: Pathology Authors: Hannah Fitzgerald Jesse L Bonin Sayeed Khan Maya Eid Sudeshna Sadhu Allison Rahtes Masharh Lipscomb Nirupam Biswas Christa Decker Melisande Nabage Ramon Bossardi Ramos Giesse Albeche Duarte Michael Marinello Anne Chen Hasan Basri Aydin Hebe Agustina Mena Source Type: research
Postoperative nursing care of a child with dilated cardiomyopathy of mismatched donor-recipient weight undergoing heart transplantation
Asian J Surg. 2023 Sep 16:S1015-9584(23)01458-6. doi: 10.1016/j.asjsur.2023.09.035. Online ahead of print.NO ABSTRACTPMID:37718210 | DOI:10.1016/j.asjsur.2023.09.035
Source: Asian Journal of Surgery - September 17, 2023 Category: Surgery Authors: Fuzhen Ma Shuping Guo Xi E Wu Yanyan Song Source Type: research
Editorial introductions
Curr Opin Organ Transplant. 2023 Jun 1;28(3):v. doi: 10.1097/MOT.0000000000001073.NO ABSTRACTPMID:37718262 | DOI:10.1097/MOT.0000000000001073
Source: Current Opinion in Organ Transplantation - September 17, 2023 Category: Transplant Surgery Source Type: research
Resolvin D2-GPR18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging
Am J Pathol. 2023 Sep 15:S0002-9440(23)00322-X. doi: 10.1016/j.ajpath.2023.08.011. Online ahead of print.ABSTRACTAging is associated with non-resolving inflammation and tissue dysfunction. Resolvin D2 (RvD2) is a pro-resolving ligand that acts through the G-protein coupled receptor (GPCR) called GPR18. Unbiased RNA sequencing revealed increased Gpr18 expression in macrophages from old mice, and in livers from elderly humans, which was associated with increased steatosis and fibrosis in middle-aged (MA) and old mice. MA mice that lack GPR18 on myeloid cells had exacerbated steatosis and hepatic fibrosis, which was associate...
Source: The American Journal of Pathology - September 17, 2023 Category: Pathology Authors: Hannah Fitzgerald Jesse L Bonin Sayeed Khan Maya Eid Sudeshna Sadhu Allison Rahtes Masharh Lipscomb Nirupam Biswas Christa Decker Melisande Nabage Ramon Bossardi Ramos Giesse Albeche Duarte Michael Marinello Anne Chen Hasan Basri Aydin Hebe Agustina Mena Source Type: research
Ciltacabtagene Autoleucel in Patients With Prior Allogeneic Stem Cell Transplant in the CARTITUDE-1 Study
CONCLUSION: Cilta-cel efficacy and safety were comparable between CARTITUDE-1 patients with and without prior alloSCT. Additional studies are needed to fully elucidate the suitability of CAR-T cell therapy in the post-alloSCT setting.PMID:37716872 | DOI:10.1016/j.clml.2023.08.012
Source: Clinical Lymphoma and Myeloma - September 16, 2023 Category: Cancer & Oncology Authors: Myo Htut Binod Dhakal Adam D Cohen Thomas Martin Jesus G Berdeja Saad Z Usmani Mounzer Agha Carolyn C Jackson Deepu Madduri William Deraedt Enrique Zudaire Tzu-Min Yeh Xiaoying Xu Lida Pacaud Muhammad Akram Sundar Jagannath Source Type: research
