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Condition: Obesity
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Total 71740 results found since Jan 2013.
The impact of body mass index changes on traumatic brain injury patients' outcomes during hospitalization
CONCLUSION: BMI is a risk factor affecting treatment results in patients with TBI, which should be controlled.PMID:37704513 | DOI:10.1016/j.cjtee.2023.08.002
Source: Chinese Journal of Traumatology - September 13, 2023 Category: Orthopaedics Authors: Bahram Aminmansour Soroush Sameri Mehdi Shafiei Mehdi Mahmoodkhani Donya Sheibani Tehrani Source Type: research
Can smartphone-based response inhibition training elicit sustained changes in appetite, preference, and cravings for energy-dense foods? A free-living randomized controlled trial
CONCLUSIONS: Although significant reductions in reward-related appetite were observed, free-living response inhibition training did not offer additional benefit over a control activity. Future intervention studies with observable food intake are needed to investigate which appetitive mechanisms most reliably predict eating behaviour over time.TRIAL REGISTRATION: Retrospectively registered with ANZCTR [ACTRN12622001502729].PMID:37704590 | DOI:10.1111/bjhp.12693
Source: British Journal of Health Psychology - September 13, 2023 Category: Psychiatry & Psychology Authors: Halim Moore Melanie J White Graham Finlayson Neil King Source Type: research
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
Cell Metab. 2023 Sep 7:S1550-4131(23)00304-2. doi: 10.1016/j.cmet.2023.08.009. Online ahead of print.ABSTRACTWeight regain after weight loss is a major challenge in the treatment of obesity. Immune cells adapt to fluctuating nutritional stress, but their roles in regulating weight regain remain unclear. Here, we identify a stem cell-like CD7+ monocyte subpopulation accumulating in the bone marrow (BM) of mice and humans that experienced dieting-induced weight loss. Adoptive transfer of CD7+ monocytes suppresses weight regain, whereas inducible depletion of CD7+ monocytes accelerates it. These cells, accumulating metabolic ...
Source: Cell Metabolism - September 13, 2023 Category: Cytology Authors: Hai-Yan Zhou Xu Feng Li-Wen Wang Rui Zhou Heng Sun Xin Chen Ren-Bin Lu Yan Huang Qi Guo Xiang-Hang Luo Source Type: research
EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events
In conclusion, these data highlight the importance of EHD2 for the integrity of the plasma membrane milieu, insulin receptor stability, and downstream insulin receptor signalling events, involved in glucose uptake and ultimately underscore its role in insulin resistance and obesity.PMID:37703099 | DOI:10.1091/mbc.E23-03-0078
Source: Mol Biol Cell - September 13, 2023 Category: Molecular Biology Authors: Mathis Neuhaus Claes Fryklund Holly Taylor Andrea Borreguero-Mu ñoz Franziska Kopietz Hamidreza Ardalani Oksana Rogova Laura Stirrat Shaun K Bremner Peter Sp égel Nia J Bryant Gwyn W Gould Karin G Stenkula Source Type: research
CROI 2023: Metabolic and Other Complications of HIV Infection
Top Antivir Med. 2023 Jun 30;31(4):538-542.ABSTRACTComorbid conditions have major impacts on the health, quality of life, and survival of people with HIV, particularly as they age. The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured excellent science related to specific comorbidities, such as cardiovascular disease (CVD), cancer, and obesity. Studies investigating factors that may contribute to CVD, such as mental health disorders, antiretroviral therapies, and activation of hormonal pathways, were featured prominently. Other studies sought to understand the epidemiology of non-AIDS-defining ca...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Sudipa Sarkar Todd T Brown Source Type: research
Gene-environment interactions that influence CVD, lipid traits, obesity, diabetes, and hypertension appear to be able to influence gene therapy
Mol Aspects Med. 2023 Sep 11;94:101213. doi: 10.1016/j.mam.2023.101213. Online ahead of print.ABSTRACTMost mind boggling diseases are accepted to be impacted by both genetic and environmental elements. As of late, there has been a flood in the improvement of different methodologies, concentrate on plans, and measurable and logical techniques to examine gene-environment cooperations (G × Es) in enormous scope studies including human populaces. The many-sided exchange between genetic elements and environmental openings has long charmed the consideration of clinicians and researchers looking to grasp the complicated starting...
Source: Molecular Medicine - September 13, 2023 Category: Molecular Biology Authors: Moataz Dowaidar Source Type: research
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC
Sci Adv. 2023 Sep 15;9(37):eadh0831. doi: 10.1126/sciadv.adh0831. Epub 2023 Sep 13.ABSTRACTThe incidence of hepatocellular carcinoma (HCC) is rapidly rising largely because of increased obesity leading to nonalcoholic steatohepatitis (NASH), a known HCC risk factor. There are no approved treatments to treat NASH. Here, we first used single-nucleus RNA sequencing to characterize a mouse model that mimics human NASH-driven HCC, the MUP-uPA mouse fed a high-fat diet. Activation of endoplasmic reticulum (ER) stress and inflammation was observed in a subset of hepatocytes that was enriched in mice that progress to HCC. We next ...
Source: Adv Data - September 13, 2023 Category: Epidemiology Authors: Ebru Boslem Saskia Reibe Rodrigo Carlessi Benoit Smeuninx Surafel Tegegne Casey L Egan Emma McLennan Lauren V Terry Max Nobis Andre Mu Cameron Nowell Neil Horadagoda Natalie A Mellett Paul Timpson Matthew Jones Elena Denisenko Alistair R R Forrest Janina Source Type: research
Exploring the anti-obesity bioactive compounds of < em > Thymelaea hirsuta < /em > and < em > Ziziphus spina-christi < /em > through integration of lipase inhibition screening and molecular docking analysis
RSC Adv. 2023 Sep 11;13(39):27167-27173. doi: 10.1039/d3ra05826c. eCollection 2023 Sep 8.ABSTRACTActivity-guided fractionation of the ethanolic extracts of Thymelaea hirsuta and Ziziphus spina-christi furnished eight compounds with pancreatic lipase inhibitory activity. Six compounds were isolated from the chloroform fraction of T. hirsuta. It is worth mentioning that this is the first report for the isolation of 5,7,4'-trihydroxy-8-methoxycarbonyl flavanol (2), daphnodorin G-3''-methyl ether (4) and daphnodorin G (5) from genus Thymelaea. Moreover, daphnoretin (1), neochamaejasmin A (3) and daphnodorin B (6) were also iso...
Source: Adv Data - September 13, 2023 Category: Epidemiology Authors: Rokia M Abdallah Hala M Hammoda Nahla S El-Gazzar Reham S Ibrahim Shaimaa M Sallam Source Type: research
Prospective Nutraceutical Effects of Cinnamon Derivatives Against Insulin Resistance in Type II Diabetes Mellitus-Evidence From the Literature
Dose Response. 2023 Sep 10;21(3):15593258231200527. doi: 10.1177/15593258231200527. eCollection 2023 Jul-Sep.ABSTRACTApart from advances in pharmaceutical antidiabetic agents, efforts are being made toward hypoglycemic agents derived from natural sources. Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory, antidiabetic, and anti-hypertriglyceridemic agent. The phytochemicals in cinnamon can be extracted from different parts of plant by distillation and solvent extraction. These chemicals help in decreasing insulin resistance and can act against hyperglycemia and d...
Source: Dose Response - September 13, 2023 Category: Drugs & Pharmacology Authors: Saima Naz Mohsin Faiza Saleem Ayesha Humayun Afifa Tanweer Ambreen Muddassir Source Type: research
Relationship between nonalcoholic fatty liver disease and bone mineral density in elderly Chinese
CONCLUSION: This study suggested that NAFLD is associated with a reduced risk of reduced heel bone mass. More research needs to be done to back up the results of this study and look into possible problems.PMID:37705028 | DOI:10.1186/s13018-023-04168-8
Source: Hand Surgery - September 13, 2023 Category: Surgery Authors: Guangheng Zhang Yingsong Zhao Siyuan Wang Qing Gong Hewei Li Source Type: research
The impact of body mass index changes on traumatic brain injury patients' outcomes during hospitalization
CONCLUSION: BMI is a risk factor affecting treatment results in patients with TBI, which should be controlled.PMID:37704513 | DOI:10.1016/j.cjtee.2023.08.002
Source: Chinese Journal of Traumatology - September 13, 2023 Category: Orthopaedics Authors: Bahram Aminmansour Soroush Sameri Mehdi Shafiei Mehdi Mahmoodkhani Donya Sheibani Tehrani Source Type: research
Alaska Native Parents' Decision-Making About Food, Beverages, and Screen Time for Young Children: Formative Insights From the "Got Neqpiaq?" Project
The objective of this study was to explore factors influencing parents' decisions about their children's foods, beverages, and activities. In focus group discussions with AN parents of young children across 12 communities, we asked about meals, traditional foods, beverages, physical activity, and screen time. All sessions were recorded, transcribed, and analyzed using open and selective coding to allow the most important themes to emerge. As parents discussed how they make decisions, several trends emerged related to adults' and children's food and beverage preferences; the impact of adult modeling on children; and how con...
Source: Rural Remote Health - September 13, 2023 Category: Rural Health Authors: Kathryn A Ohle Kathryn R Koller Amanda K Walch Flora R Lee Lea Palmer Jennifer Nu Timothy K Thomas Source Type: research
Interleukin-38 and insulin resistance
We present that IL-38 associated signaling can be a potential target for the treatment of insulin resistance and associated diseases.PMID:37702180 | DOI:10.2174/1871530323666230911114150
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 13, 2023 Category: Endocrinology Authors: Kamil Klejbuk Marek Str ączkowski Source Type: research
Association of Obesity Based on Different Metabolic Status with Risk of Gout Occurrence in Patients: A National Study
CONCLUSION: When metabolic abnormalities were present, obesity induced a higher risk of gout. Different components of metabolic abnormalities had different effects on the risk of gout occurrence, and the number of metabolic abnormalities was closely related to the risk of gout occurrence. Follow-up and intervention methods targeting obesity and metabolic abnormalities should be considered for patients with gout.PMID:37702179 | DOI:10.2174/1871530323666230911140635
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 13, 2023 Category: Endocrinology Authors: Yanyan Wang Xiude Fan Xu Hou Luna Liu Shizhan Ma Junming Han Zhixiang Wang Source Type: research
Proteomic Analysis by 4D Label-free MS-PRM Provides Insight into the Role and Regulatory Mechanisms of IL-25 in NK cells
CONCLUSION: Proteomics combined with bioinformatic analysis will help to mine more information hidden behind mass spectrometry data and lay the foundation for finding clinical biomarkers and mechanisms of diseases.PMID:37702163 | DOI:10.2174/0929866530666230911164329
Source: Protein and Peptide Letters - September 13, 2023 Category: Biochemistry Authors: Juan Feng Luoyao Huang Shuaipeng Yang Jiasheng Pan Xiangxing Zhu Dongsheng Tang Source Type: research
