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Condition: Obesity
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Infant body composition: A comprehensive overview of assessment techniques, nutrition factors, and health outcomes
Nutr Clin Pract. 2023 Oct;38 Suppl 2:S7-S27. doi: 10.1002/ncp.11059.ABSTRACTBody composition assessment is a valuable tool for clinical assessment and research that has implications for long-term health. Unlike traditional measurements such as anthropometrics or body mass index, body composition assessments provide more accurate measures of body fatness and lean mass. Moreover, depending on the technique, they can offer insight into regional body composition, bone mineral density, and brown adipose tissue. Various methods of body composition assessment exist, including air displacement plethysmography, dual-energy x-ray ab...
Source: Nutrition in Clinical Practice - September 18, 2023 Category: Nutrition Authors: Maggie L Jerome Vivian Valcarce Laura Lach Elena Itriago Ariel A Salas Source Type: research
Plasma metanephrines yield fewer false-positive results than urine metanephrines in obstructive sleep apnea patients
CONCLUSION: In OSA patients, plasma metanephrines are less likely to yield false-positive results for the diagnosis of PPGL than 24-hour urinary metanephrines. In patients with suspected OSA, obesity or a family history of hypertension, plasma metanephrines may be the preferred first-line test to avoid unnecessary anxiety or follow-up.PMID:37721483 | DOI:10.1210/clinem/dgad553
Source: The Journal of Clinical Endocrinology and Metabolism - September 18, 2023 Category: Endocrinology Authors: Thomas F J King Yingjuan Mok Lily Mae Dacay Hang Siang Wong Pon Poh Hsu Alvin Tan Kang Min Wong Ehsan Saffari Seyed Jacques W M Lenders Troy H Puar Source Type: research
Reduced risk of de novo Barrett esophagus after bariatric surgery: a national database study
CONCLUSION: Patients who underwent bariatric surgery (RYGB or SG) had a lower risk of being diagnosed with BE compared with screening colonoscopy controls who did not receive bariatric surgery. This effect appears to be largely mediated by reduction in weight and BMI.PMID:37722939 | DOI:10.1016/j.soard.2023.08.009
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - September 18, 2023 Category: Surgery Authors: Alexander Hurtado Apoorva K Chandar Jaime Abraham Perez Regina Casselberry Scott A Martin Kayla DeLano Mujjahid Abbas Amitabh Chak Source Type: research
Dietary fat and lipid metabolism in the tumor microenvironment
Biochim Biophys Acta Rev Cancer. 2023 Sep 16:188984. doi: 10.1016/j.bbcan.2023.188984. Online ahead of print.ABSTRACTMetabolic reprogramming has been considered a core hallmark of cancer, in which excessive accumulation of lipids promote cancer initiation, progression and metastasis. Lipid metabolism is often considered as the digestion and absorption process of dietary fat, and the ways in which cancer cells utilize lipids are often influenced by the complex interactions within the tumor microenvironment. Among multiple cancer risk factors, obesity has a positive association with multiple cancer types, while diets like ca...
Source: Biochimica et Biophysica Acta - September 18, 2023 Category: Biochemistry Authors: Swagata Goswami Qiming Zhang Cigdem Elif Celik Ethan M Reich Ömer H Yilmaz Source Type: research
Prevalence and Management of Obesity in U.S. Adults With Type 1 Diabetes
Ann Intern Med. 2023 Sep;176(9):eL230228. doi: 10.7326/L23-0228.NO ABSTRACTPMID:37722124 | DOI:10.7326/L23-0228
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: Michael Fang Justin B Echouffo-Tcheugui Elizabeth Selvin Source Type: research
Physiological effects of exercise in heat while wearing a polyester versus cotton T-shirt in physically active men with obesity: a pilot study
CONCLUSIONS: The current findings do not support the superiority of polyester or cotton sportwear for better thermoregulatory, perspiratory, and cardiovascular regulations in physically active men with obesity. Future research should examine the effectiveness of other alternative fabrics of sportwear for better physiological responses when exercising in the heat, particularly in adults with obesity.PMID:37721720 | DOI:10.23736/S0022-4707.23.15164-4
Source: Methods of Information in Medicine - September 18, 2023 Category: Information Technology Authors: Abdulaziz A Masoud Abdullah B Alansare Alfred E Finch Source Type: research
Analysis of experimental injuries to obese occupants with different postures in frontal impact
The objective of the present study was to analyze injuries and their patterns to obese occupants in frontal impacts with upright and reclined postures using experimental data. Twelve obese post-mortem human subjects (PMHS) were positioned on a sled buck with seatback angles of 250 or 450 from the vertical, termed as upright and reclined postures. They were restrained with a seat belt and pretensioner. Frontal impact tests were conducted at 8.9 or 13.9 m/s, termed as low and high velocities. After the test, x-rays and CTs were taken, and an autopsy was conducted. The Maximum AIS (MAIS) and Injury Severity Score (ISS) were c...
Source: Accident; Analysis and Prevention. - September 18, 2023 Category: Accident Prevention Authors: Narayan Yoganandan Karthik Somasundaram Frank Pintar Source Type: research
CRISPR/Cas9-mediated deletion of adipocyte genes associated with NAFLD alters adipocyte lipid handling and reduces steatosis in hepatocytes < em > in vitro < /em >
Am J Physiol Cell Physiol. 2023 Sep 18. doi: 10.1152/ajpcell.00291.2023. Online ahead of print.ABSTRACTObesity is a major risk factor for the development of non-alcoholic fatty liver disease (NAFLD) and the subcutaneous white adipose tissue (scWAT) is the primary lipid storage depot and regulates lipid fluxes to other organs. Our previous work identified genes up-regulated in scWAT of patients with NAFLD: SOCS3, DUSP1, and SIK1. Herein, we knocked down (KD) their expression in human adipose-derived mesenchymal stem cells (hADMSCs) using CRISPR/Cas9 technology and characterized their phenotype. We found that SOCS3, DUSP1, a...
Source: Am J Physiol Cell Ph... - September 18, 2023 Category: Cytology Authors: Marta Lopez-Yus Scott Frendo-Cumbo Raquel Del Moral-Bergos Maria Pilar Garcia-Sobreviela Vanesa Bernal-Monterde Mikael Ryd én Silvia Lorente-Cebrian Jose M Arbones-Mainar Source Type: research
Health profile of workers from different industries in Singapore
CONCLUSION: Health issues are prevalent in the workforce and may affect work and employee safety. It is increasingly important for employees' health to be considered in risk assessments and prioritised in workplace safety and health management systems and strategies. Health promotion interventions should be targeted, and multilevel and multicomponent initiatives should be integrated with pre-existing occupational safety programmes.PMID:37721304 | DOI:10.4103/singaporemedj.SMJ-2021-414
Source: Singapore Medical Journal - September 18, 2023 Category: General Medicine Authors: Sin Eng Chia Mei Ling Tan Elise Cheok Peh Woon Ong Source Type: research
Cultural adaptations and methodological innovations to group model building for the systems actions to reduce malnutrition in all its forms in Southeast Asian countries and China (SYSTAM CHINA-SEACS International Consortium) project
CONCLUSIONS: Cultural and methodological adaptations to the common GMB process for an Asian LMIC setting were successful. The 'hybrid' GMB format is feasible, cost-effective, and more environmentally friendly. These cultural adaptations could be considered for other Asian settings and beyond to address inter-related, complex issues such as MIAIF.PMID:37723534 | PMC:PMC10506199 | DOI:10.1186/s12966-023-01510-5
Source: Health Physics - September 18, 2023 Category: Physics Authors: Bai Li Zouyan He Remco Peters Steven Allender Yunfeng Zou Weiwen Zhou Jianfeng Lao Bee Koon Poh Boyd Swinburn Source Type: research
Physiological effects of exercise in heat while wearing a polyester versus cotton T-shirt in physically active men with obesity: a pilot study
CONCLUSIONS: The current findings do not support the superiority of polyester or cotton sportwear for better thermoregulatory, perspiratory, and cardiovascular regulations in physically active men with obesity. Future research should examine the effectiveness of other alternative fabrics of sportwear for better physiological responses when exercising in the heat, particularly in adults with obesity.PMID:37721720 | DOI:10.23736/S0022-4707.23.15164-4
Source: Health Physics - September 18, 2023 Category: Physics Authors: Abdulaziz A Masoud Abdullah B Alansare Alfred E Finch Source Type: research
CRISPR/Cas9-mediated deletion of adipocyte genes associated with NAFLD alters adipocyte lipid handling and reduces steatosis in hepatocytes < em > in vitro < /em >
Am J Physiol Cell Physiol. 2023 Sep 18. doi: 10.1152/ajpcell.00291.2023. Online ahead of print.ABSTRACTObesity is a major risk factor for the development of non-alcoholic fatty liver disease (NAFLD) and the subcutaneous white adipose tissue (scWAT) is the primary lipid storage depot and regulates lipid fluxes to other organs. Our previous work identified genes up-regulated in scWAT of patients with NAFLD: SOCS3, DUSP1, and SIK1. Herein, we knocked down (KD) their expression in human adipose-derived mesenchymal stem cells (hADMSCs) using CRISPR/Cas9 technology and characterized their phenotype. We found that SOCS3, DUSP1, a...
Source: American Journal of Physiology. Cell Physiology - September 18, 2023 Category: Cytology Authors: Marta Lopez-Yus Scott Frendo-Cumbo Raquel Del Moral-Bergos Maria Pilar Garcia-Sobreviela Vanesa Bernal-Monterde Mikael Ryd én Silvia Lorente-Cebrian Jose M Arbones-Mainar Source Type: research
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management. A narrative review focusing on principal risk modifiers
Expert Rev Clin Pharmacol. 2023 Sep 18. doi: 10.1080/17512433.2023.2259306. Online ahead of print.ABSTRACTINTRODUCTION: Metabolic syndrome (MetS), i.e. the cluster of cardiometabolic risk factors comprising visceral obesity, impaired glucose metabolism, arterial hypertension and atherogenic dyslipidemia, is prevalent globally and exacts a heavy toll on health care expenditures.AREAS COVERED: The pathophenotypes of individual traits of the MetS in adults are discussed first, with strong emphasis on nonalcoholic fatty liver disease (NAFLD) and sex differences. Next, I discuss recent studies on phenotypic and outcome heteroge...
Source: Pharmacological Reviews - September 18, 2023 Category: Drugs & Pharmacology Authors: Amedeo Lonardo Source Type: research
Ethnicity and risk factors among Indian coronary artery disease patients
In this study, an attempt was made to investigate the distribution of coronary risk factors in male patients with coronary artery disease (CAD)(n=50 each) belonging to Jaat and Vaishya castes. A Significantly higher average height, waist and hip circumferences, glucose, and waist-height ratio were observed in Jaats compared to the Vaishyas (p=0.000). Mean BMI, total cholesterol (total-C) and non-high density lipoprotein cholesterol (HDL-C), and lean body mass index (LBMI) were significantly higher in Vaishyas against Jaats (p=0.00). A significantly higher percentage of type 2 diabetes(T2DM) (p=0.03) and isolated hypertrigl...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Monika Sah Latheef Saa Venkataramana P Source Type: research
