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Condition: Obesity
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Total 71740 results found since Jan 2013.
Correction: Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesity
Mol Med. 2023 Sep 19;29(1):128. doi: 10.1186/s10020-023-00723-5.NO ABSTRACTPMID:37726670 | DOI:10.1186/s10020-023-00723-5
Source: Molecular Medicine - September 19, 2023 Category: Molecular Biology Authors: Xiaoxia Xiao Huiling Hu Yadi Zhong Yingjian Chen Kaijia Tang Zhisen Pan Jiawen Huang Xiaoying Yang Qi Wang Yong Gao Source Type: research
A comprehensive review of genetic causes of obesity
CONCLUSIONS: Genetic study technologies are in constant development; however, we are still far from having a personalized approach to genetic causes of obesity. A significant proportion of the affected individuals are associated with genetic causes; however, there are still barriers to its approach, as it continues to be underdiagnosed. Video Abstract (MP4 1041807 KB).PMID:37725322 | DOI:10.1007/s12519-023-00757-z
Source: World Journal of Pediatrics : WJP - September 19, 2023 Category: Pediatrics Authors: Marcio Jos é Concepción-Zavaleta Juan Eduardo Quiroz-Aldave Mar ía Del Carmen Durand-Vásquez Elman Rolando Gamarra-Osorio Juan Del Carmen Valencia de la Cruz Claudia Mercedes Barrueto-Callirgos Susan Luciana Puelles-Le ón Elena de Jes ús Alvarado-Le Source Type: research
Detection of binucleated nephrin-marked podocytes by flow cytometry in the urine of patients with obesity
J Nephrol. 2023 Sep 19. doi: 10.1007/s40620-023-01730-9. Online ahead of print.NO ABSTRACTPMID:37725279 | DOI:10.1007/s40620-023-01730-9
Source: Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Almudena G Carrasco Adriana Izquierdo-Lahuerta Ignacio Gonz ález de Pablos Rocio Vila-Bedmar Marina Martin-Taboada Esteban Porrini Enrique Morales Gema Medina-G ómez Source Type: research
The impact of calorie labelling and proportional pricing on out of home food orders: a randomised controlled trial study using a virtual food and drink delivery app
CONCLUSIONS: Calorie labelling on food delivery platforms may effectively reduce calories ordered. Proportional pricing may be useful in prompting consumers to select smaller portion sizes, although further research in real-world settings will now be valuable.PMID:37726788 | DOI:10.1186/s12966-023-01513-2
Source: Health Physics - September 19, 2023 Category: Physics Authors: Amy Finlay Emma Boyland Andrew Jones Rozemarijn Witkam Eric Robinson Source Type: research
A comparison of chronic conditions and health characteristics between cancer survivors and non-cancer survivors
DISCUSSION: These findings can be used by healthcare and public health practitioners to evaluate the programmatic efforts and resources, implement targeted interventions toward cancer survivors, and improve health and quality of life.PMID:37724026 | DOI:10.1177/17423953231180191
Source: Chronic Illness - September 19, 2023 Category: General Medicine Authors: Anjin Singh Michael Shayne Gallaway Addey Rascon Source Type: research
Prediction of large-for-gestational age at 36 weeks' gestation: two-dimensional vs three-Dimensional vs magnetic resonance imaging
CONCLUSION: At 36 WG, MRI performs better than 2D-US and 3D-US in predicting birthweight > 95th percentile at birth, especially in patients at high-risk for macrosomia, while 2D-US and 3D-US are comparable. For low-risk patients, the three modalities perform similarly. This article is protected by copyright. All rights reserved.PMID:37725758 | DOI:10.1002/uog.27485
Source: The Ultrasound Review of Obstetrics and Gynecology - September 19, 2023 Category: Radiology Authors: E Mazzone C Kadji M M Cannie D A Badr J C Jani Source Type: research
Transcription Repression of CRY2 via PER2 Interaction Promotes Adipogenesis
Mol Cell Biol. 2023 Sep 19:1-15. doi: 10.1080/10985549.2023.2253710. Online ahead of print.ABSTRACTThe circadian clock is driven by a transcriptional-translational feedback loop, and cryptochrome 2 (CRY2) represses CLOCK/BMAL1-induced transcription activation. Despite the established role of clock in adipogenic regulation, whether the CRY2 repressor activity functions in adipocyte biology remains unclear. Here we identify a critical cysteine residue of CRY2 that mediates interaction with Period 2 (PER2). We further demonstrate that this mechanism is required for repressing circadian clock-controlled Wnt signaling to promot...
Source: Mol Biol Cell - September 19, 2023 Category: Molecular Biology Authors: Weini Li Xuekai Xiong Tali Kiperman Ke Ma Source Type: research
Gestational Diabetes Mellitus: Update on Screening, Diagnosis, and Management
Am Fam Physician. 2023 Sep;108(3):249-258.ABSTRACTGestational diabetes mellitus (GDM) is a common condition of pregnancy with increasing prevalence in the United States. GDM increases risks of complications, including operative delivery, hypertensive disorders, shoulder dystocia, fetal macrosomia, large-for-gestational-age infants, neonatal hypoglycemia, and neonatal respiratory distress. In patients who are overweight or obese, prepregnancy weight loss and lifestyle modifications during pregnancy may prevent GDM. First-trimester screening can identify preexisting diabetes and early-onset GDM for prompt implementation of g...
Source: American Family Physician - September 19, 2023 Category: Primary Care Authors: Joshua S Will Holly Crellin Source Type: research
Osteopontin-driven T-cell accumulation and function in adipose tissue and liver promoted insulin resistance and MAFLD
CONCLUSIONS: Current findings highlight a critical role of SPP1 in the initiation of obesity-driven chronic inflammation by regulating accumulation and/or polarization of T cells. Early targeting of SPP1 could be beneficial for IR and MAFLD treatment.PMID:37724058 | DOI:10.1002/oby.23868
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Fr édéric Soysouvanh D éborah Rousseau St éphanie Bonnafous Manon Bourinet Axelle Strazzulla St éphanie Patouraux Jean Machowiak Marwin A Farrugia Antonio Iannelli Albert Tran Rodolphe Anty Carmelo Luci Philippe Gual Source Type: research
Association of shift work with oxidative stress and alteration of fasting plasma glucose level in Chinese adults
CONCLUSIONS: These findings suggest that shift work is positively associated with blood glucose, and the association is partially mediated by oxidative stress.PMID:37724057 | DOI:10.1002/oby.23845
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Wenzhen Li Xiaobing Feng Haozhe Zhang Yi-Xin Wang Qiang Zeng Chong Liu Victor W Zhong Dongming Wang Source Type: research
Modeling BMI z score lability during childhood as a function of child temperament and genetic risk for obesity
CONCLUSIONS: These findings provide insights into factors that can be harnessed to redirect unhealthy trajectories as well as factors that may challenge redirection or maintain a healthy trajectory.PMID:37724056 | DOI:10.1002/oby.23867
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Chang Liu Jenae M Neiderhiser Nilam Ram Leslie D Leve Daniel S Shaw Misaki N Natsuaki David Reiss Jody M Ganiban Source Type: research
Associations and predictive performance of 11 anthropometric measures with incident type 2 diabetes: A prospective cohort study from the UK Biobank
CONCLUSIONS: Although most adiposity markers were associated with type 2 diabetes, the magnitude of the associations differed. WHtR had the strongest associations and predictive ability for type 2 diabetes and thus could be a more suitable marker for clinical use.PMID:37724055 | DOI:10.1002/oby.23849
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Jirapitcha Boonpor Solange Parra-Soto Atefeh Talebi Ziyi Zhou Fernanda Carrasco-Marin Fanny Petermann-Rocha Paul Welsh Jill P Pell Naveed Sattar Jason M R Gill Stuart R Gray Carlos Celis-Morales Frederick K Ho Source Type: research
Metabolic syndrome-related cognitive impairment with white matter hyperintensities and functional network analysis
CONCLUSIONS: WMHs mediated the association between MetS and cognitive function, with a decline in the efficiency of functional brain networks being a probable neural mechanism.PMID:37724054 | DOI:10.1002/oby.23873
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Wenhui Zheng Xia Zhou Jiabin Yin Han Liu Wenwen Yin Wei Zhang Xiaoqun Zhu Zhongwu Sun Source Type: research
Risk factors for metabolic syndrome in self-identified and questioning sexual minority women
CONCLUSIONS: Self-identified and questioning SMW did not have an increased incidence of MetS compared with heterosexual women, but they had higher odds of large waist circumference and low high-density lipoprotein, respectively. Further studies are needed to identify the gaps in social determinants of health in SMW.PMID:37723848 | DOI:10.1002/oby.23879
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Young Mee Choi Courtney S Pilkerton Jun Xiang Amie M Ashcraft Keri A Seymour Nova Szoka Source Type: research
Evaluation of safety and efficacy of allogeneic adipose tissue-derived mesenchymal stem cells in pediatric bronchiolitis obliterans syndrome (BoS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT)
CONCLUSIONS: AT-MSCs could be safely administered to our pediatric cases with BoS post-allo-HSCT. Considering their advanced stage of disease, their sub-optimal functional capacity due to steroid-induced complications, and COVID-19 infection post-treatment, we believe that AT-MSC therapy can have possible efficacy in the management of pediatric BoS. The conduction of further studies with larger sample sizes and more frequent injections is prudent for further optimization of AT-MSC therapy against BoS. Trial registration Iranian Registry of Clinical Trials (IRCT), IRCT20201202049568N2. Registered 22 February 2021, https://e...
Source: Cell Research - September 19, 2023 Category: Cytology Authors: Rashin Mohseni Pouya Mahdavi Sharif Maryam Behfar Mohammad Reza Modaresi Rohola Shirzadi Mahta Mardani Leila Jafari Fahimeh Jafari Zeynab Nikfetrat Amir Ali Hamidieh Source Type: research
