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Condition: Obesity

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Can smartphone-based response inhibition training elicit sustained changes in appetite, preference, and cravings for energy-dense foods? A free-living randomized controlled trial
CONCLUSIONS: Although significant reductions in reward-related appetite were observed, free-living response inhibition training did not offer additional benefit over a control activity. Future intervention studies with observable food intake are needed to investigate which appetitive mechanisms most reliably predict eating behaviour over time.TRIAL REGISTRATION: Retrospectively registered with ANZCTR [ACTRN12622001502729].PMID:37704590 | DOI:10.1111/bjhp.12693
Source: British Journal of Health Psychology - September 13, 2023 Category: Psychiatry & Psychology Authors: Halim Moore Melanie J White Graham Finlayson Neil King Source Type: research

Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
Cell Metab. 2023 Sep 7:S1550-4131(23)00304-2. doi: 10.1016/j.cmet.2023.08.009. Online ahead of print.ABSTRACTWeight regain after weight loss is a major challenge in the treatment of obesity. Immune cells adapt to fluctuating nutritional stress, but their roles in regulating weight regain remain unclear. Here, we identify a stem cell-like CD7+ monocyte subpopulation accumulating in the bone marrow (BM) of mice and humans that experienced dieting-induced weight loss. Adoptive transfer of CD7+ monocytes suppresses weight regain, whereas inducible depletion of CD7+ monocytes accelerates it. These cells, accumulating metabolic ...
Source: Cell Metabolism - September 13, 2023 Category: Cytology Authors: Hai-Yan Zhou Xu Feng Li-Wen Wang Rui Zhou Heng Sun Xin Chen Ren-Bin Lu Yan Huang Qi Guo Xiang-Hang Luo Source Type: research

Prospective Nutraceutical Effects of Cinnamon Derivatives Against Insulin Resistance in Type II Diabetes Mellitus-Evidence From the Literature
Dose Response. 2023 Sep 10;21(3):15593258231200527. doi: 10.1177/15593258231200527. eCollection 2023 Jul-Sep.ABSTRACTApart from advances in pharmaceutical antidiabetic agents, efforts are being made toward hypoglycemic agents derived from natural sources. Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory, antidiabetic, and anti-hypertriglyceridemic agent. The phytochemicals in cinnamon can be extracted from different parts of plant by distillation and solvent extraction. These chemicals help in decreasing insulin resistance and can act against hyperglycemia and d...
Source: Dose Response - September 13, 2023 Category: Drugs & Pharmacology Authors: Saima Naz Mohsin Faiza Saleem Ayesha Humayun Afifa Tanweer Ambreen Muddassir Source Type: research

Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
Cell Metab. 2023 Sep 7:S1550-4131(23)00304-2. doi: 10.1016/j.cmet.2023.08.009. Online ahead of print.ABSTRACTWeight regain after weight loss is a major challenge in the treatment of obesity. Immune cells adapt to fluctuating nutritional stress, but their roles in regulating weight regain remain unclear. Here, we identify a stem cell-like CD7+ monocyte subpopulation accumulating in the bone marrow (BM) of mice and humans that experienced dieting-induced weight loss. Adoptive transfer of CD7+ monocytes suppresses weight regain, whereas inducible depletion of CD7+ monocytes accelerates it. These cells, accumulating metabolic ...
Source: Cell Metabolism - September 13, 2023 Category: Cytology Authors: Hai-Yan Zhou Xu Feng Li-Wen Wang Rui Zhou Heng Sun Xin Chen Ren-Bin Lu Yan Huang Qi Guo Xiang-Hang Luo Source Type: research

Proteomic Analysis by 4D Label-free MS-PRM Provides Insight into the Role and Regulatory Mechanisms of IL-25 in NK cells
CONCLUSION: Proteomics combined with bioinformatic analysis will help to mine more information hidden behind mass spectrometry data and lay the foundation for finding clinical biomarkers and mechanisms of diseases.PMID:37702163 | DOI:10.2174/0929866530666230911164329
Source: Protein and Peptide Letters - September 13, 2023 Category: Biochemistry Authors: Juan Feng Luoyao Huang Shuaipeng Yang Jiasheng Pan Xiangxing Zhu Dongsheng Tang Source Type: research

Can smartphone-based response inhibition training elicit sustained changes in appetite, preference, and cravings for energy-dense foods? A free-living randomized controlled trial
CONCLUSIONS: Although significant reductions in reward-related appetite were observed, free-living response inhibition training did not offer additional benefit over a control activity. Future intervention studies with observable food intake are needed to investigate which appetitive mechanisms most reliably predict eating behaviour over time.TRIAL REGISTRATION: Retrospectively registered with ANZCTR [ACTRN12622001502729].PMID:37704590 | DOI:10.1111/bjhp.12693
Source: British Journal of Health Psychology - September 13, 2023 Category: Psychiatry & Psychology Authors: Halim Moore Melanie J White Graham Finlayson Neil King Source Type: research

CROI 2023: Metabolic and Other Complications of HIV Infection
Top Antivir Med. 2023 Jun 30;31(4):538-542.ABSTRACTComorbid conditions have major impacts on the health, quality of life, and survival of people with HIV, particularly as they age. The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured excellent science related to specific comorbidities, such as cardiovascular disease (CVD), cancer, and obesity. Studies investigating factors that may contribute to CVD, such as mental health disorders, antiretroviral therapies, and activation of hormonal pathways, were featured prominently. Other studies sought to understand the epidemiology of non-AIDS-defining ca...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Sudipa Sarkar Todd T Brown Source Type: research

Can smartphone-based response inhibition training elicit sustained changes in appetite, preference, and cravings for energy-dense foods? A free-living randomized controlled trial
CONCLUSIONS: Although significant reductions in reward-related appetite were observed, free-living response inhibition training did not offer additional benefit over a control activity. Future intervention studies with observable food intake are needed to investigate which appetitive mechanisms most reliably predict eating behaviour over time.TRIAL REGISTRATION: Retrospectively registered with ANZCTR [ACTRN12622001502729].PMID:37704590 | DOI:10.1111/bjhp.12693
Source: British Journal of Health Psychology - September 13, 2023 Category: Psychiatry & Psychology Authors: Halim Moore Melanie J White Graham Finlayson Neil King Source Type: research

Proteomic Analysis by 4D Label-free MS-PRM Provides Insight into the Role and Regulatory Mechanisms of IL-25 in NK cells
CONCLUSION: Proteomics combined with bioinformatic analysis will help to mine more information hidden behind mass spectrometry data and lay the foundation for finding clinical biomarkers and mechanisms of diseases.PMID:37702163 | DOI:10.2174/0929866530666230911164329
Source: Protein and Peptide Letters - September 13, 2023 Category: Biochemistry Authors: Juan Feng Luoyao Huang Shuaipeng Yang Jiasheng Pan Xiangxing Zhu Dongsheng Tang Source Type: research

Prospective Nutraceutical Effects of Cinnamon Derivatives Against Insulin Resistance in Type II Diabetes Mellitus-Evidence From the Literature
Dose Response. 2023 Sep 10;21(3):15593258231200527. doi: 10.1177/15593258231200527. eCollection 2023 Jul-Sep.ABSTRACTApart from advances in pharmaceutical antidiabetic agents, efforts are being made toward hypoglycemic agents derived from natural sources. Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory, antidiabetic, and anti-hypertriglyceridemic agent. The phytochemicals in cinnamon can be extracted from different parts of plant by distillation and solvent extraction. These chemicals help in decreasing insulin resistance and can act against hyperglycemia and d...
Source: Dose Response - September 13, 2023 Category: Drugs & Pharmacology Authors: Saima Naz Mohsin Faiza Saleem Ayesha Humayun Afifa Tanweer Ambreen Muddassir Source Type: research

The impact of body mass index changes on traumatic brain injury patients' outcomes during hospitalization
CONCLUSION: BMI is a risk factor affecting treatment results in patients with TBI, which should be controlled.PMID:37704513 | DOI:10.1016/j.cjtee.2023.08.002
Source: Chinese Journal of Traumatology - September 13, 2023 Category: Orthopaedics Authors: Bahram Aminmansour Soroush Sameri Mehdi Shafiei Mehdi Mahmoodkhani Donya Sheibani Tehrani Source Type: research

Prospective Nutraceutical Effects of Cinnamon Derivatives Against Insulin Resistance in Type II Diabetes Mellitus-Evidence From the Literature
Dose Response. 2023 Sep 10;21(3):15593258231200527. doi: 10.1177/15593258231200527. eCollection 2023 Jul-Sep.ABSTRACTApart from advances in pharmaceutical antidiabetic agents, efforts are being made toward hypoglycemic agents derived from natural sources. Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory, antidiabetic, and anti-hypertriglyceridemic agent. The phytochemicals in cinnamon can be extracted from different parts of plant by distillation and solvent extraction. These chemicals help in decreasing insulin resistance and can act against hyperglycemia and d...
Source: Dose Response - September 13, 2023 Category: Drugs & Pharmacology Authors: Saima Naz Mohsin Faiza Saleem Ayesha Humayun Afifa Tanweer Ambreen Muddassir Source Type: research

Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
Cell Metab. 2023 Sep 7:S1550-4131(23)00304-2. doi: 10.1016/j.cmet.2023.08.009. Online ahead of print.ABSTRACTWeight regain after weight loss is a major challenge in the treatment of obesity. Immune cells adapt to fluctuating nutritional stress, but their roles in regulating weight regain remain unclear. Here, we identify a stem cell-like CD7+ monocyte subpopulation accumulating in the bone marrow (BM) of mice and humans that experienced dieting-induced weight loss. Adoptive transfer of CD7+ monocytes suppresses weight regain, whereas inducible depletion of CD7+ monocytes accelerates it. These cells, accumulating metabolic ...
Source: Cell Metabolism - September 13, 2023 Category: Cytology Authors: Hai-Yan Zhou Xu Feng Li-Wen Wang Rui Zhou Heng Sun Xin Chen Ren-Bin Lu Yan Huang Qi Guo Xiang-Hang Luo Source Type: research