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Procedure: Gastroschisis Repair

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Creation of a Quality Payment Program Measure for Mismatch Repair or Microsatellite Instability Biomarker Testing Status in Colorectal, Endometrial, Gastroesophageal, or Small Bowel Carcinoma
CONCLUSIONS.—: The Mismatch Repair or Microsatellite Instability Biomarker Testing Status in Colorectal Carcinoma, Endometrial, Gastroesophageal, or Small Bowel Carcinoma measure was appropriately specified, and testing demonstrated that it is well suited for characterizing the quality of pathologists' communication of MMR and/or MSI status.PMID:37708308 | DOI:10.5858/arpa.2022-0418-OA
Source: Archives of Pathology and Laboratory Medicine - September 14, 2023 Category: Laboratory Medicine Authors: Gregary T Bocsi Jennifer Laudadio Richa Jain Sarah M Eakin Amarpreet Bhalla Jonathan A Rosenberg Jennifer K Maratt Sonia S Kupfer David A Leiman Diana M Cardona Source Type: research

3D interconnected porous PMMA scaffold integrating with advanced nanostructured CaP-based biomaterials for rapid bone repair and regeneration
J Mech Behav Biomed Mater. 2023 Sep 7;147:106106. doi: 10.1016/j.jmbbm.2023.106106. Online ahead of print.ABSTRACTBioactive scaffolds with polymer and nanostructured bioactive glass-based composites are promising materials for regenerative applications in consequence of close mimics of natural bone composition. Poly methyl methacrylate (PMMA) is a highly preferred thermoplastic polymer for orthopedic applications as it has good biocompatibility. Different kinds of bioactive, biodegradable as well as biocompatible biomaterial composites such as Bioglass (BG), Hydroxyapatite (Hap), and Tricalcium phosphate (TCP) can be integ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - September 14, 2023 Category: Materials Science Authors: K Elakkiya P Bargavi S Balakumar Source Type: research

Multifunctional wet-adhesive chitosan/acrylic conduit for sutureless repair of peripheral nerve injuries
This study aimed to develop easily implantable chitosan-based peripheral nerve repair conduits that combine acrylic acid and cleavable N-hydroxysuccinimide to reduce nerve damage during repair. In ex vivo tissue adhesion tests, the conduit achieved maximal interfacial toughness of 705 J m-2 ± 30 J m-2, allowing continuous bridging of the severed nerve ends. Adhesive repair significantly reduces local inflammation caused by conventional sutures, and the positive charge of chitosan disrupts the bacterial cell wall and reduces implant-related infections. This promises to open new avenues for sutureless nerve repair and relia...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Meng Zhang Heng An Zhen Gu Yi-Chong Zhang Teng Wan Hao-Ran Jiang Feng-Shi Zhang Bao-Guo Jiang Na Han Yong-Qiang Wen Pei-Xun Zhang Source Type: research

Hormesis Defines The Limits Of Lifespan
Ageing Res Rev. 2023 Sep 12:102074. doi: 10.1016/j.arr.2023.102074. Online ahead of print.ABSTRACTThis commentary provides a novel synthesis of how biological systems adapt to a broad spectrum of environmental and age-related stresses that are underlying causes of numerous degenerative diseases and debilitating effects of aging. It proposes that the most fundamental, evolutionary-based integrative strategy to sustain and protect health is based on the concept of hormesis. This concept integrates anti-oxidant, anti-inflammatory and cellular repair responses at all levels of biological organization (i.e., cell, organ and org...
Source: Ageing Research Reviews - September 14, 2023 Category: Genetics & Stem Cells Authors: Edward J Calabrese Naomi Osakabe Rosanna Di Paola Rosalba Siracusa Roberta Fusco Ramona D'Amico Daniela Impellizzeri Salvatore Cuzzocrea Tilman Fritsch Ali S Abdelhameed Uwe Wenzel Claudio Franceschi V Calabrese Source Type: research

Transvaginal excision of vaginal paraurethral leiomyoma: A video case report
CONCLUSION: The procedure was successful in obtaining anatomical repair and relieving symptoms. This approach represents a valid procedure for the surgical management of this uncommon condition.PMID:37708657 | DOI:10.1016/j.ejogrb.2023.09.008
Source: Reproductive Biology - September 14, 2023 Category: Reproduction Medicine Authors: Clarissa Costa Marta Barba Alice Cola Matteo Frigerio Source Type: research

Centromere: A Trojan horse for genome stability
DNA Repair (Amst). 2023 Sep 7;130:103569. doi: 10.1016/j.dnarep.2023.103569. Online ahead of print.ABSTRACTCentromeres play a key role in the maintenance of genome stability to prevent carcinogenesis and diseases. They are specialized chromosome loci essential to ensure faithful transmission of genomic information across cell generations by mediating the interaction with spindle microtubules. Nonetheless, while fulfilling these essential roles, their distinct repetitive composition and susceptibility to mechanical stresses during cell division render them susceptible to breakage events. In this review, we delve into the pr...
Source: DNA Repair - September 14, 2023 Category: Genetics & Stem Cells Authors: Andrea Scelfo Daniele Fachinetti Source Type: research

Primary Uncomplicated Ventral Hernia Repair: Guidelines and Practice Patterns for Routine Hernia Repairs
Surg Clin North Am. 2023 Oct;103(5):901-915. doi: 10.1016/j.suc.2023.04.004. Epub 2023 May 8.ABSTRACTSurgical repair of primary umbilical and epigastric hernias are among the most common abdominal operations in the world. The hernia defects range from small (<1 cm) to large and complex even in the absence of prior incision or repair. Mesh has generally been shown to decrease recurrence rates, and its use and location of placement should be individualized for each patient. Open, laparoscopic, and robotic approaches provide unique considerations for the technical aspects of primary repair with or without mesh augmentation...
Source: The Surgical Clinics of North America - September 14, 2023 Category: Surgery Authors: Matthew Hager Colston Edgerton William W Hope Source Type: research

Stuck prosthetic mitral valve after AV canal defect repair: Intraoperative 3D transesophageal echocardiography diagnosis
Ann Card Anaesth. 2023 Apr-Jun;26(2):239-240. doi: 10.4103/aca.aca_89_22.NO ABSTRACTPMID:37706399 | PMC:PMC10284482 | DOI:10.4103/aca.aca_89_22
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Avneet Singh Sunder Negi Sachin Mahajan Source Type: research

Primary Tissue Repair for Inguinal Hernias: The Shouldice Repair Technique and Patient Selection
Surg Clin North Am. 2023 Oct;103(5):859-873. doi: 10.1016/j.suc.2023.04.001. Epub 2023 May 9.ABSTRACTIt is estimated that approximately one in four men and one in 20 women will develop an inguinal hernia over the course of their lifetime. A non-mesh inguinal hernia repair via the Shouldice technique is a unique approach that necessitates dissection of the entire groin region as well as careful assessment for any secondary hernias. Subsequently, a pure tissue laminated closure allows the repair to be performed without tension. Herein, the authors describe a brief overview of inguinal hernias and discuss the relevant patient...
Source: The Surgical Clinics of North America - September 14, 2023 Category: Surgery Authors: Divyansh Agarwal Robert D Sinyard Lauren Ott Michael Reinhorn Source Type: research

Hernia Prevention: The Role of Technique and Prophylactic Mesh to Prevent Incisional Hernias
This article aims to critically summarize the use of surgical technique and prophylactic mesh augmentation during fascial closure to inform decision-making and reduce incisional hernia formation.PMID:37709391 | DOI:10.1016/j.suc.2023.04.021
Source: The Surgical Clinics of North America - September 14, 2023 Category: Surgery Authors: Noah DeAngelo Arielle J Perez Source Type: research

Hernia Mesh Complications: Management of Mesh Infections and Enteroprosthetic Fistula
Surg Clin North Am. 2023 Oct;103(5):1029-1042. doi: 10.1016/j.suc.2023.04.011. Epub 2023 May 12.ABSTRACTThe potential consequences of mesh infection mandate careful consideration of surgical approach, mesh selection, and preoperative patient optimization when planning for ventral hernia repair. Intraperitoneal mesh, microporous or laminar mesh, and multifilament mesh typically require explantation, whereas macroporous, monofilament mesh in an extraperitoneal position is often salvageable. Delayed presentation of mesh infection should raise the suspicion for enteroprosthetic fistula when intraperitoneal mesh is present. Whe...
Source: The Surgical Clinics of North America - September 14, 2023 Category: Surgery Authors: Kathryn A Schlosser Jeremy A Warren Source Type: research

Devices in Hernia Surgery
This article summarizes some of the key controversies and points regarding mesh materials and regulatory processes related to mesh devices.PMID:37709386 | DOI:10.1016/j.suc.2023.04.009
Source: The Surgical Clinics of North America - September 14, 2023 Category: Surgery Authors: Ajita S Prabhu Source Type: research

Use of extracorporeal membrane oxygenation and cerebral oximetry in a stage 1 norwood repair for hypoplastic left heart syndrome
We report a case where the use of ECMO was beneficial after stage I Norwood palliation with severe ventricular dysfunction. The systemic-to-pulmonary artery shunt was kept open to balance the systemic and pulmonary circulations. Cerebral oximetry can be useful as an additional monitoring modality to guide management, monitor cerebral perfusion, and help detect cerebral steal.PMID:37706390 | PMC:PMC10284473 | DOI:10.4103/0971-9784.320955
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Anam A Kazi Kamlesh B Tailor M C Manoj Smruti Ranjan Mohanty Source Type: research

Outcome of obstructed total anamalous pulmonary venous connection (TAPVC) repair patients with milrinone versus milrinone and inhaled nitric oxide (INO): A prospective randomized observational study
CONCLUSION: Most of the patients with obstructed TAPVC had severe PAH. Management of severe PAH with a combination of milrinone with iNO had a better outcome than milrinone alone.PMID:37706383 | PMC:PMC10284474 | DOI:10.4103/aca.aca_56_22
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Srikanth Gujja Mrugesh Prajapati Tanya R Chuada Hemang Gandhi Varun Arora Vivek Kaul Sanjay Patel Source Type: research

Inverting the DNA tetrahedron: A novel strategy for sensitive and stable detection of aging-related enzyme MMP2
Anal Chim Acta. 2023 Oct 16;1278:341736. doi: 10.1016/j.aca.2023.341736. Epub 2023 Aug 17.ABSTRACTIn the current study, a novel electrochemiluminescence biosensor based on the entropy-driven DNA tetrahedron for the detection of matrix metalloproteinase 2 (MMP2), an enzyme that regulates extracellular matrix remodeling and affects aging was reported. The biosensor utilizes an inverted DNA tetrahedron structure, which exposes three vertices to the solution, as molecular recognition units for capturing specific biomolecules. The biosensor also employs a ratiometric method and an entropy-driven reaction, which enhance the resp...
Source: Analytica Chimica Acta - September 14, 2023 Category: Chemistry Authors: Jihua Wei Zichun Song Jiuying Cui Yuanxun Gong Qianli Tang Kai Zhang Xinlei Song Xianjiu Liao Source Type: research