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Procedure: Gastroschisis Repair
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Total 54334 results found since Jan 2013.
NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicity
Toxicol Appl Pharmacol. 2023 Sep 14:116688. doi: 10.1016/j.taap.2023.116688. Online ahead of print.ABSTRACTChemical modifications in messenger RNA (mRNA) regulate gene expression and play critical roles in stress responses and diseases. Recently we have shown that N6-methyladenosine (m6A), the most abundant mRNA modification, promotes the repair of UVB-induced DNA damage by regulating global genome nucleotide excision repair (GG-NER). However, the roles of other mRNA modifications in the UVB-induced damage response remain understudied. N4-acetylcytidine (ac4C) is deposited in mRNA by the RNA-binding acetyltransferase NAT10...
Source: Toxicology and Applied Pharmacology - September 16, 2023 Category: Toxicology Authors: Zizhao Yang Emma Wilkinson Yan-Hong Cui Haixia Li Yu-Ying He Source Type: research
Low Expression of A3C and PLP2 Indicating a Favorable Prognosis in Human Gliomas
In conclusion, our results not only confirmed A3C played an important role in glioma development, but the A3C IHC test could successfully predict the therapeutic effects and disease prognosis.PMID:37715423 | DOI:10.14715/cmb/2023.69.7.12
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Jong-Shiaw Jin Yu-Ling Tsai Yu-Chan Chang Wen-Chiuan Tsai Source Type: research
The repair and regeneration mechanism of platelet-rich fibrin-promoting tissue after alveolar bone defect through the notch pathway
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):85-90. doi: 10.14715/cmb/2023.69.7.14.ABSTRACTThis work investigated the effects of platelet-rich fibrin (PRF) combined with bone mesenchymal stem cells (BMSCs) on the repair of alveolar bone defect (ABD) and the related mechanism of the Notch1/Wnt3a signaling pathway. 28 healthy male New Zealand white rabbits were selected to prepare the BMSCs and PRF. Rabbits were rolled into a combination group (implanted with PRF + BMSCs for treatment), a PRF group (treated with PRF) a BMSC group (BMSCs for treatment), and a control group (Ctrl group, no material implantation), with 7 r...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Tao Li Hui Long Wei Niu Bo Feng Source Type: research
Beyond BMI: Exploring Body Composition's Role in Long Term Outcome of Elective Abdominal Aortic Aneurysm Repair
Eur J Vasc Endovasc Surg. 2023 Sep 14:S1078-5884(23)00743-8. doi: 10.1016/j.ejvs.2023.08.068. Online ahead of print.NO ABSTRACTPMID:37716471 | DOI:10.1016/j.ejvs.2023.08.068
Source: PubMed: Eur J Vasc Endovasc ... - September 16, 2023 Category: Surgery Authors: Lisa B Westenberg Robert A Pol Source Type: research
Three-dimensional Anatomy of the Velopharyngeal Muscles in the Cleft Palate
CONCLUSIONS: With the help of Micro-CT technology, detailed anatomical features and the relationship between muscles could be visualized. In the specimen with cleft palate, muscles in the soft palate were associated with the pharyngeal muscles, which formed the 3D "velopharyngeal muscles complex." These findings provide anatomical evidence for muscle reconstruction in cleft palate repair.PMID:37715628 | DOI:10.1177/10556656231176867
Source: The Cleft Palate-Craniofacial Journal - September 16, 2023 Category: ENT & OMF Authors: Jiuli Zhao Hengyuan Ma Yongqian Wang Tao Song Di Wu Ningbei Yin Source Type: research
Live cell transcription-coupled nucleotide excision repair dynamics revisited
In this study, we employ knock-in cell lines designed to target the endogenous CSB gene locus with mClover, a GFP variant. Through live cell imaging, we uncover the intricate molecular dynamics of CSB in response to physiologically relevant UV doses. We showed that the DNA damage-induced association of CSB with chromatin is tightly regulated by the CSA-containing ubiquitin-ligase CRL complex (CRL4CSA). Combining the CSB-mClover knock-in cell line with SILAC-based GFP-mediated complex isolation and mass-spectrometry-based proteomics, revealed novel putative CSB interactors as well as discernible variations in complex compos...
Source: DNA Repair - September 16, 2023 Category: Genetics & Stem Cells Authors: Diana A Llerena Schiffmacher Katarzyna W Kliza Arjan F Theil Gert-Jan Kremers Jeroen A A Demmers Tomoo Ogi Michiel Vermeulen Wim Vermeulen Alex Pines Source Type: research
Correction to: ORCHID: A phase II study of Olaparib in Metastatic Renal Cell Carcinoma Patients HarborIng a BAP1 or Other DNA Repair Gene Mutations
Oncologist. 2023 Sep 16:oyad265. doi: 10.1093/oncolo/oyad265. Online ahead of print.NO ABSTRACTPMID:37715956 | DOI:10.1093/oncolo/oyad265
Source: The Oncologist - September 16, 2023 Category: Cancer & Oncology Source Type: research
Live cell transcription-coupled nucleotide excision repair dynamics revisited
In this study, we employ knock-in cell lines designed to target the endogenous CSB gene locus with mClover, a GFP variant. Through live cell imaging, we uncover the intricate molecular dynamics of CSB in response to physiologically relevant UV doses. We showed that the DNA damage-induced association of CSB with chromatin is tightly regulated by the CSA-containing ubiquitin-ligase CRL complex (CRL4CSA). Combining the CSB-mClover knock-in cell line with SILAC-based GFP-mediated complex isolation and mass-spectrometry-based proteomics, revealed novel putative CSB interactors as well as discernible variations in complex compos...
Source: DNA Repair - September 16, 2023 Category: Genetics & Stem Cells Authors: Diana A Llerena Schiffmacher Katarzyna W Kliza Arjan F Theil Gert-Jan Kremers Jeroen A A Demmers Tomoo Ogi Michiel Vermeulen Wim Vermeulen Alex Pines Source Type: research
Curettage and colour-A technique for defining tumour depth on the ear in the Mohs and non-Mohs setting
Australas J Dermatol. 2023 Sep 15. doi: 10.1111/ajd.14158. Online ahead of print.ABSTRACTFor tumours of the ear that are suspected to involve auricular cartilage, precise definition of the extent of involved deep margin can be difficult. As large resections of cartilage can be cosmetically disfiguring with limited repair options, we propose a simple and effective technique to facilitate a targeted deep margin resection using a curette and a surgical marking pen.PMID:37715356 | DOI:10.1111/ajd.14158
Source: The Australasian Journal of Dermatology - September 16, 2023 Category: Dermatology Authors: Thomas Pagliaro Jazlyn Read Source Type: research
Contribution and therapeutic value of mitophagy in cerebral ischemia-reperfusion injury after cardiac arrest
Biomed Pharmacother. 2023 Sep 14;167:115492. doi: 10.1016/j.biopha.2023.115492. Online ahead of print.ABSTRACTCardiopulmonary resuscitation and related life support technologies have improved substantially in recent years; however, mortality and disability rates from cardiac arrest (CA) remain high and are closely associated with the high incidence of cerebral ischemia-reperfusion injury (CIRI), which is explained by a "double-hit" model (i.e., resulting from both ischemia and reperfusion). Mitochondria are important power plants in the cell and participate in various biochemical processes, such as cell differentiation and...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Zheng Li Jihong Xing Source Type: research
NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicity
Toxicol Appl Pharmacol. 2023 Sep 14:116688. doi: 10.1016/j.taap.2023.116688. Online ahead of print.ABSTRACTChemical modifications in messenger RNA (mRNA) regulate gene expression and play critical roles in stress responses and diseases. Recently we have shown that N6-methyladenosine (m6A), the most abundant mRNA modification, promotes the repair of UVB-induced DNA damage by regulating global genome nucleotide excision repair (GG-NER). However, the roles of other mRNA modifications in the UVB-induced damage response remain understudied. N4-acetylcytidine (ac4C) is deposited in mRNA by the RNA-binding acetyltransferase NAT10...
Source: Toxicology and Applied Pharmacology - September 16, 2023 Category: Toxicology Authors: Zizhao Yang Emma Wilkinson Yan-Hong Cui Haixia Li Yu-Ying He Source Type: research
Three-dimensional Anatomy of the Velopharyngeal Muscles in the Cleft Palate
CONCLUSIONS: With the help of Micro-CT technology, detailed anatomical features and the relationship between muscles could be visualized. In the specimen with cleft palate, muscles in the soft palate were associated with the pharyngeal muscles, which formed the 3D "velopharyngeal muscles complex." These findings provide anatomical evidence for muscle reconstruction in cleft palate repair.PMID:37715628 | DOI:10.1177/10556656231176867
Source: The Cleft Palate-Craniofacial Journal - September 16, 2023 Category: ENT & OMF Authors: Jiuli Zhao Hengyuan Ma Yongqian Wang Tao Song Di Wu Ningbei Yin Source Type: research
Beyond BMI: Exploring Body Composition's Role in Long Term Outcome of Elective Abdominal Aortic Aneurysm Repair
Eur J Vasc Endovasc Surg. 2023 Sep 14:S1078-5884(23)00743-8. doi: 10.1016/j.ejvs.2023.08.068. Online ahead of print.NO ABSTRACTPMID:37716471 | DOI:10.1016/j.ejvs.2023.08.068
Source: PubMed: Eur J Vasc Endovasc ... - September 16, 2023 Category: Surgery Authors: Lisa B Westenberg Robert A Pol Source Type: research
Contribution and therapeutic value of mitophagy in cerebral ischemia-reperfusion injury after cardiac arrest
Biomed Pharmacother. 2023 Sep 14;167:115492. doi: 10.1016/j.biopha.2023.115492. Online ahead of print.ABSTRACTCardiopulmonary resuscitation and related life support technologies have improved substantially in recent years; however, mortality and disability rates from cardiac arrest (CA) remain high and are closely associated with the high incidence of cerebral ischemia-reperfusion injury (CIRI), which is explained by a "double-hit" model (i.e., resulting from both ischemia and reperfusion). Mitochondria are important power plants in the cell and participate in various biochemical processes, such as cell differentiation and...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Zheng Li Jihong Xing Source Type: research
Curettage and colour-A technique for defining tumour depth on the ear in the Mohs and non-Mohs setting
Australas J Dermatol. 2023 Sep 15. doi: 10.1111/ajd.14158. Online ahead of print.ABSTRACTFor tumours of the ear that are suspected to involve auricular cartilage, precise definition of the extent of involved deep margin can be difficult. As large resections of cartilage can be cosmetically disfiguring with limited repair options, we propose a simple and effective technique to facilitate a targeted deep margin resection using a curette and a surgical marking pen.PMID:37715356 | DOI:10.1111/ajd.14158
Source: The Australasian Journal of Dermatology - September 16, 2023 Category: Dermatology Authors: Thomas Pagliaro Jazlyn Read Source Type: research
