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Highlighting the use of micro and nanoparticles based-drug delivery systems for the treatment of < em > Helicobacter pylori < /em > infections
Crit Rev Microbiol. 2021 Mar 16:1-26. doi: 10.1080/1040841X.2021.1895721. Online ahead of print.ABSTRACTDue to the high adaptability of Helicobacter pylori and the low targeting specificity of the drugs normally used in pharmacological therapy, the strains are becoming increasingly resistant to these drugs, making it difficult to eradicate the infection. Thus, the search for new therapeutic approaches has been considered urgent. The incorporation of drugs in advanced drug delivery systems, such as nano and microparticles, would allow the improvement of the retention time in the stomach and the prolongation of drug release ...
Source: Critical Reviews in Microbiology - March 16, 2021 Category: Microbiology Authors: Maur ício Palmeira Chaves de Souza Bruna Almeida Furquim de Camargo Larissa Sp ósito Giovanna Capaldi Fortunato Gabriela Corr êa Carvalho Gabriel Davi Marena Andr éia Bagliotti Meneguin Ta ís Maria Bauab Marlus Chorilli Source Type: research

Current progress and prospects of organic nanoparticles against bacterial biofilm
Adv Colloid Interface Sci. 2021 Jun 30;294:102475. doi: 10.1016/j.cis.2021.102475. Online ahead of print.ABSTRACTBiofilm plays a vital role in the pathogenicity and resistance of bacteria, and is an important problem to be settled urgently in the treatment of bacterial diseases. Exploring effective strategies to control bacterial biofilm has become a hot research topic. Compared to other measures, organic nanomaterials have shown greater prospects in overcoming the problems of bacterial biofilms due to their unique properties. In order to explore more effective organic nanomaterials against biofilms, we used relevant keywo...
Source: Advances in Colloid and Interface Science - July 19, 2021 Category: Chemistry Authors: Xinyao Li Dongmei Chen Shuyu Xie Source Type: research

Improvement of laccase biosensor characteristics using sulfur-doped TiO < sub > 2 < /sub > nanoparticles
Bioelectrochemistry. 2022 Jul 25;147:108215. doi: 10.1016/j.bioelechem.2022.108215. Online ahead of print.ABSTRACTThe search for new nanoscale materials with predictable properties to target the timely and fast detection of toxic components in wastewater is one of the most promising directions of modern biosensorics. We have shown that TiO2 nanoparticles modified with sulfur significantly improve the main operational parameters of laccase-based electrodes when compared with controls. The nanoparticle samples were labeled as TiO2S(0.75), TiO2S(1.5), and TiO2S(3.0), in which the numbers in parentheses refer to the quantity o...
Source: Bioelectrochemistry - August 7, 2022 Category: Biochemistry Authors: Taras Kavetskyy Oleh Smutok Olha Demkiv Yuliia Kukhazh Nataliya Stasyuk Evhen Leonenko Arnold Kiv Yoshinori Kobayashi Atsushi Kinomura Ondrej Šauša Mykhailo Gonchar Evgeny Katz Source Type: research

Citrus limon phytocompounds decorated nanoparticles control poultry pathogens
In this study, we employed molecular docking to evaluate lemon peel phytochemical's protein binding capability against various poultry pathogens. The nanoparticles (LP AgNPs) obtained from the lemon peel were characterized and tested for their antibacterial activity against more poultry pathogens. LP AgNPs were characterized by using UV-Visible absorption spectra, which revealed an absorption peak at a wavelength of 420-440 nm. The FT-IR analysis demonstrated that flavonoids and phenolic acids acted as capping, reducing, and stabilizing agents during the biosynthesis of AgNPs. EDAX showed a strong peak was observed at 3 ke...
Source: Archives of Microbiology - March 21, 2023 Category: Microbiology Authors: K Srividhyaa S Ranjani S Hemalatha Source Type: research

Using Robots and Artificial Intelligence to Search for New Medicines
Courtesy of Dr. Adam Gormley. Adam Gormley, Ph.D., describes himself as a creative and adventurous person—albeit, not creative in the traditional sense. “Science allows me to be creative; to me, it’s a form of art. I love being outdoors, going on sailing trips, and spending time adventuring with my family. Research is the same—it’s an adventure. My creative and adventurous sides have combined into a real love for science,” he says. Dr. Gormley currently channels his passion for science into his position as an assistant professor of biomedical engineering at Rutgers University in Piscataway, New Jersey. Lea...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 24, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Bioinformatics Computational Biology Medicines Profiles Source Type: blogs

Synthesis and characterization of γ-ferric oxide nanoparticles and their effect on Solanum lycopersicum.
Abstract γ-Ferric oxide nanoparticles are synthesized through modern and facile ayurvedic route followed by normal and special purification steps, which are both cost-effective and eco-friendly. These synthesized γ-ferric oxide nanoparticles were applied on Solanum lycopersicum to search the effect on chlorophyll content. This process involves multiple filtration and calcination steps. The synthesized samples were analyzed by X-ray diffraction (XRD), UV-visible (UV-vis) spectroscopy, transmission electron microscopy (TEM), vibrating sample magnetometry (VSM), and particle size analysis (PSA) to identify the puri...
Source: Environmental Science and Pollution Research International - August 23, 2015 Category: Environmental Health Authors: Pavani T, Rao KV, Chakra CS, Prabhu YT Tags: Environ Sci Pollut Res Int Source Type: research