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Total 4543034 results found since Jan 2013.
Reversible rearrangement of magnetic nanoparticles in solution studied using time-resolved SAXS method
Superparamagnetic nanoparticles have broad applications in biology and medicines. Quantitative measurements of magnetic beads in solution are essential in gaining comprehensive understanding of their dynamics and developing applications. Here, using synchrotron X-ray sources combined with well controlled magnetic fields, the results from small-angle X-ray scattering (SAXS) experiments on superparamagnetic particles in solution under the influence of external magnetic fields are reported. The particles mostly remain in monodispersed states and the linear aggregates tend to be aligned with the external magnetic field. After ...
Source: Journal of Synchrotron Radiation - June 10, 2019 Category: Physics Authors: Huang, L. Mai, J. Zhu, Q. Guo, Z. Qin, S. Yang, P. Li, X. Shi, Y. Wang, X. Wang, Q. Li, N. Xie, C. Liu, H. Tags: superparamagnetic nanoparticles small-angle X-ray scattering magnetic fields dynamic assembly monodispersed states time-resolved dynamics research papers Source Type: research
Cluster-mining: an approach for determining core structures of metallic nanoparticles from atomic pair distribution function data
A novel approach for finding and evaluating structural models of small metallic nanoparticles is presented. Rather than fitting a single model with many degrees of freedom, libraries of clusters from multiple structural motifs are built algorithmically and individually refined against experimental pair distribution functions. Each cluster fit is highly constrained. The approach, called cluster-mining, returns all candidate structure models that are consistent with the data as measured by a goodness of fit. It is highly automated, easy to use, and yields models that are more physically realistic and result in better agreeme...
Source: Acta Crystallographica Section A - December 17, 2019 Category: Chemistry Authors: Banerjee, S. Liu, C.-H. Jensen, K.M. Ø Juh á s, P. Lee, J.D. Tofanelli, M. Ackerson, C.J. Murray, C.B. Billinge, S.J.L. Tags: structural models nanoparticles clusters pair distribution functions data mining screening research papers Source Type: research
Determination of the melting temperature of spherical nanoparticles in dilute solution as a function of their radius by exclusively using the small-angle X-ray scattering technique
In this investigation the dependence on radius of the melting temperature of dilute sets of spherical nanocrystals with wide radius distributions was determined by a novel procedure exclusively using the results of small-angle X-ray scattering (SAXS) measurements. This procedure is based on the sensitivity of the SAXS function to small and rather sharp variations in the size and electron density of nanocrystals at their melting temperature. The input for this procedure is a set of experimental SAXS intensity functions at selected q values for varying sample temperatures. In practice, the sample is heated from a minimum tem...
Source: Journal of Applied Crystallography - March 24, 2020 Category: Physics Authors: Kellermann, G. Pereira, F.L.C. Craievich, A.F. Tags: small-angle X-ray scattering SAXS melting nanoparticles thermal expansion size-dependent contraction research papers Source Type: research
Signature of antiphase boundaries in iron oxide nanoparticles
Iron oxide nanoparticles find a wide variety of applications, including targeted drug delivery and hyperthermia in advanced cancer treatment methods. An important property of these particles is their maximum net magnetization, which has been repeatedly reported to be drastically lower than the bulk reference value. Previous studies have shown that planar lattice defects known as antiphase boundaries (APBs) have an important influence on the particle magnetization. The influence of APBs on the atomic spin structure of nanoparticles with the γ -Fe2O3 composition is examined via Monte Carlo simulations, explicitly considerin...
Source: Journal of Applied Crystallography - November 16, 2021 Category: Physics Authors: K ö hler, T. Feoktystov, A. Petracic, O. Nandakumaran, N. Cervellino, A. Br ü ckel, T. Tags: nanoparticles X-ray powder diffraction Monte Carlo simulations Debye scattering equation antiphase boundaries research papers Source Type: research
What to use instead of NICE Evidence Search - some recommendations (sort of)
In an earlier post I searched NICE Evidence Search (closing at the end of March 2022) and then a number of other sources to see which other sources would find the material.I found 27 results (vertigo epley was the search) in NICE Evidence Search. 5 were systematic reviews from DARE, which I decided I was not too worried about, as DARE has not been updated for some timeThen there were results from PubMed, Cochrane, BestBets, CKS, four health organisations, Patient.info, NICE and the Royal Australian College of GPs.SearchingCochraneitself found one more Cochrane review than NICE Evidence Search did. So, more...
Source: Browsing - March 10, 2022 Category: Databases & Libraries Tags: NICE Evidence Search Source Type: blogs
Nanoparticles for targeted delivery of antioxidant enzymes to the brain after cerebral ischemia and reperfusion injury
& Mark S Kindy
Source: Journal of Cerebral Blood Flow - February 6, 2013 Category: Neurology Authors: Xiang YunVictor D MaximovJin YuHong ZhuAlexey A VertegelMark S Kindy Tags: anti-oxidants antibody cerebral ischemia nanoparticles superoxide dismutase Source Type: research
Certain types of iron oxide nanoparticles are not suited to passively target inflammatory cells that infiltrate the brain in response to stroke
as Endres, Ulrich Dirnagl
& Tracy D Farr
Source: Journal of Cerebral Blood Flow - February 27, 2013 Category: Neurology Authors: Christoph HarmsAnna Lena DatwylerFrank WiekhorstLutz TrahmsRandall LindquistEyk SchellenbergerSusanne MuellerGunnar SchützFarnoosh RoohiAndreas IdeMartina FüchtemeierKaren GertzGolo KronenbergUlrike HarmsMatthias EndresUlrich DirnaglTracy D Farr Tags: inflammation iron oxide nanoparticles magnetic resonance imaging stroke Source Type: research
Prevalence, Characteristics and Clinical Diagnosis of Maturity Onset Diabetes of the Young Due to Mutations in HNF1A, HNF4A, and Glucokinase: Results from the SEARCH for Diabetes in Youth.
Conclusions/Interpretation:In this systematic study of MODY in a large pediatric US diabetes cohort, unselected by referral pattern or family history, MODY was usually misdiagnosed and incorrectly treated with insulin. While many type 2 diabetes-like metabolic features were less common in the mutation-positive group, no single characteristic identified all patients with mutations. Clinicians should be alert to the possibility of MODY diagnosis, particularly in antibody negative youth with diabetes.
PMID: 23771925 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - June 14, 2013 Category: Endocrinology Authors: Gilliam LK, Pihoker C, Ellard S, Hattersley AT, Dabelea D, Davis C, Dolan LM, Greenbaum CJ, Imperatore G, Lawrence JM, Marcovina SM, Mayer-Davis E, Rodriguez BL, Steck AK, Williams DE, for the SEARCH for Diabetes in Youth Study Group Tags: J Clin Endocrinol Metab Source Type: research
SAXS characterization of polymer-embedded hollow nanoparticles and of their shell porosityThis article will form part of a virtual special issue of the journal, presenting some highlights of the 15th International Small-Angle Scattering Conference (SAS2012). This special issue will be available in late 2013/early 2014.
Size parameters of SiO2/TiO2 hollow nanoparticles (HNPs) of 25–100 nm in diameter were characterized by small-angle X-ray scattering (SAXS). On the basis of the decoupling and the Percus–Yevick approximations, and using a hollow sphere model, size information on HNPs was extracted, including average outer diameter, average inner diameter and polydispersity. Application of an alternative form factor based on hollow ellipsoids, and of a sticky hard sphere structure factor, did not improve the fit significantly. The shell porosity of the HNPs and the size of the pores in the HNP shell were further characterized by combi...
Source: Journal of Applied Crystallography - November 7, 2013 Category: Physics Authors: Chen, Z.H.Hwang, S.H.Zeng, X.Roh, J.Jang, J.Ungar, G. Tags: hollow nanoparticles small-angle X-ray scattering research papers Source Type: research
Combined fitting of small- and wide-angle X-ray total scattering data from nanoparticles: benefits and issues
Simultaneous fitting of small- (SAS) and wide-angle (WAS) X-ray total scattering data for nanoparticles has been explored using both simulated and experimental signals. The nanoparticle types included core/shell metal and quantum-dot CdSe systems. Various combinations of reciprocal- and real-space representations of the scattering data have been considered. Incorporating SAS data into the fit consistently returned more accurate particle-size distribution parameters than those obtained by fitting the WAS data alone. A popular method for fitting the Fourier transform of the WAS data (i.e. a pair-distribution function), in wh...
Source: Journal of Applied Crystallography - March 19, 2014 Category: Physics Authors: Gagin, A.Allen, A.J.Levin, I. Tags: small- and wide-angle X-ray scattering nanoparticles research papers Source Type: research
Metastable adaptive orthorhombic martensite in zirconia nanoparticles
Reported here are observations of isolated orthorhombic (o) ZrO2 nanoparticles (NPs) in the Pbca space group under atmospheric conditions. These NPs are composed of o domains separated by internal semi-coherent boundaries. They are identified to transform from lamellar-twinned tetragonal (t) NPs. The constraining effect of the twin boundaries impedes a direct martensitic transformation to the monoclinic (m) phase but favours a transformation to the o phase. The internal boundaries are considered to evolve from the lamellar-twinning boundaries, playing an important role in the stabilization of the o structure under atmosphe...
Source: Journal of Applied Crystallography - March 19, 2014 Category: Physics Authors: Liu, S.Hu, W.Zhang, Y.Xiang, J.Wen, F.Xu, B.He, J.Yu, D.Tian, Y.Liu, Z. Tags: zirconia nanoparticles constrained martensitic transformation orthorhombic phases interfaces twinning research papers Source Type: research
Systemically administered brain-targeted nanoparticles transport peptides across the blood–brain barrier and provide neuroprotection
Systemically administered brain-targeted nanoparticles transport peptides across the blood–brain barrier and provide neuroprotection
Journal of Cerebral Blood Flow & Metabolism advance online publication, December 10 2014.
doi:10.1038/jcbfm.2014.220
Authors: Muge Yemisci, Secil Caban, Yasemin Gursoy-Ozdemir, Sevda Lule, Ramon Novoa-Carballal, Ricardo Riguera, Eduardo Fernandez-Megia, Karine Andrieux, Partick Couvreur, Yilmaz Capan & Turgay Dalkara
Source: Journal of Cerebral Blood Flow - December 10, 2014 Category: Neurology Authors: Muge YemisciSecil CabanYasemin Gursoy-OzdemirSevda LuleRamon Novoa-CarballalRicardo RigueraEduardo Fernandez-MegiaKarine AndrieuxPartick CouvreurYilmaz CapanTurgay Dalkara Tags: cerebrovascular disease/stroke caspases growth factors/cytokines nanoparticles neuroprotection Source Type: research
Oral delivery of capsaicin using MPEG-PCL nanoparticles
mp; Wei-ming Zhang
Source: Acta Pharmacologica Sinica - January 5, 2015 Category: Drugs & Pharmacology Authors: Wei PengXin-yi JiangYuan ZhuE Omari-SiawWen-wen DengJiang-nan YuXi-ming XuWei-ming Zhang Tags: MPEG-PCL nanoparticles capsaicin pharmacokinetics gastric mucosa irritation Source Type: research
Dr. Google steps up its medical search game again
By better leveraging its Knowledge Graph smart search algorithm, Google is giving its health-related search functions a shot in the arm. Starting in the next few days, health searches on Google and via the Google app will display a wide range of medical facts about the disease or condition in question. “We’ll show you typical symptoms […]
Source: mobihealthnews - February 10, 2015 Category: Information Technology Authors: Jonah Comstock Tags: Uncategorized DIY health Google Google Knowledge Graph Google search health information search Mayo Clinic medical search online diagnosers video visits virtual visits Source Type: news
Systemically administered brain-targeted nanoparticles transport peptides across the blood–brain barrier and provide neuroprotection
Systemically administered brain-targeted nanoparticles transport peptides across the blood–brain barrier and provide neuroprotection
Journal of Cerebral Blood Flow & Metabolism 35,
469 (March 2015). doi:10.1038/jcbfm.2014.220
Authors: Muge Yemisci, Secil Caban, Yasemin Gursoy-Ozdemir, Sevda Lule, Ramon Novoa-Carballal, Ricardo Riguera, Eduardo Fernandez-Megia, Karine Andrieux, Partick Couvreur, Yilmaz Capan & Turgay Dalkara
Source: Journal of Cerebral Blood Flow and Metabolism - February 27, 2015 Category: Neuroscience Authors: Muge YemisciSecil CabanYasemin Gursoy-OzdemirSevda LuleRamon Novoa-CarballalRicardo RigueraEduardo Fernandez-MegiaKarine AndrieuxPartick CouvreurYilmaz CapanTurgay Dalkara Tags: cerebrovascular disease/stroke caspases growth factors/cytokines nanoparticles neuroprotection Source Type: research
