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Total 4543034 results found since Jan 2013.

FDA, Google met to discuss use of search to find adverse drug reactions
Google met with the FDA last month to discuss the possibility of the FDA using Google search data to learn about drug side effects, according to a report in Bloomberg, which spotted a public record of the meeting and secured additional information from an FDA spokesperson. The talk appears to have been an informal, early-stage discussion on […]
Source: mobihealthnews - July 16, 2015 Category: Information Technology Authors: Jonah Comstock Tags: Government/Regulation adverse drug reaction adverse event FDA FDA adverse event reporting Google Google search side effects Source Type: news

Ben Miller on the search for alien life - podcast
Why are we so fascinated by the idea that we aren’t alone in the universe?Since abandoning his PhD in Physics at Cambridge for a career in comedy, Ben Miller has returned to his roots, publishing his first popular science book, It’s Not Rocket Science in 2012 and now The Aliens are Coming, published this month.In the book, Ben looks at animal intelligence; the latest search for alien intelligence; and the conditions needed to kickstart life. And he asks what evolution can tell us about extraterrestrial life. Continue reading...
Source: Guardian Unlimited Science - February 12, 2016 Category: Science Authors: Nicola Davis, Iain Chambers and Kit Buchan Tags: Science Alien life Seti (Search for Extraterrestrial Intelligence) Astronomy Space Source Type: news

Molecular symmetry-constrained systematic search approach to structure solution of the coiled-coil SRGAP2 F-BARx domain
SRGAP2 (Slit – Robo GTPase-activating protein 2) is a cytoplasmic protein found to be involved in neuronal branching, restriction of neuronal migration and restriction of the length and density of dendritic postsynaptic spines. The extended F-BAR (F-BARx) domain of SRGAP2 generates membrane protrusions when expressed in COS-7 cells, while most F-BARs induce the opposite effect: membrane invaginations. As a first step to understand this discrepancy, the F-BARx domain of SRGAP2 was isolated and crystallized after co-expression with the carboxy domains of the protein. Diffraction data were collected from two significantly n...
Source: Acta Crystallographica Section D - November 28, 2016 Category: Biochemistry Authors: Sporny, M. Guez-Haddad, J. Waterman, D.G. Isupov, M.N. Opatowsky, Y. Tags: exhaustive search SRGAP2 F-BAR coiled coil molecular replacement research papers Source Type: research

Combinatorial refinement of thin-film microstructure, properties and process conditions: iterative nanoscale search for self-assembled TiAlN nanolamellae
Because of the tremendous variability of crystallite sizes and shapes in nanomaterials, it is challenging to assess the corresponding size – property relationships and to identify microstructures with particular physical properties or even optimized functions. This task is especially difficult for nanomaterials formed by self-organization, where the spontaneous evolution of microstructure and properties is coupled. In this work, two compositionally graded TiAlN films were (i) grown using chemical vapour deposition by applying a varying ratio of reacting gases and (ii) subsequently analysed using cross-sectional synchrotr...
Source: Journal of Applied Crystallography - November 30, 2016 Category: Physics Authors: Zalesak, J. Todt, J. Pitonak, R. K ö pf, A. Wei ß enbacher, R. Sartory, B. Burghammer, M. Daniel, R. Keckes, J. Tags: X-ray nanodiffraction thin films nanomaterials combinatorial search research papers Source Type: research

Authors' reply re: Surrogacy: a family-building option in search of legitimacy.
Source: BJOG : An International Journal of Obstetrics and Gynaecology - May 27, 2017 Category: OBGYN Authors: Authors' reply re: Surrogacy: a family-building option in search of legitimacy. Tags: BJOG Source Type: research

Everybody lies: how Google search reveals our darkest secrets
What can we learn about ourselves from the things we ask online? US data scientist Seth Stephens ‑Davidowitz analysed anonymous Google search results, uncovering disturbing truths about our desires, beliefs and prejudicesEverybody lies. People lie about how many drinks they had on the way home. They lie about how often they go to the gym, how much those new shoes cost, whether they read that book. They call in sick when they ’re not. They say they’ll be in touch when they won’t. They say it’s not about you when it is. They say they love you when they don’t. They say they’re happy while in the dumps. They say ...
Source: Guardian Unlimited Science - July 9, 2017 Category: Science Authors: Seth Stephens-Davidowitz Tags: Google Books Alphabet Technology Big data Search engines Internet Psychology Science Race issues World news Culture Source Type: news

Obesity, risk of biochemical recurrence, and prostate ‐specific antigen doubling time after radical prostatectomy: results from the SEARCH database
ConclusionWhile we confirmed that higher BMI was associated with BCR, we found no link between BMI and PSADT at the time of recurrence. Our data suggest obese men do not have more aggressive recurrences. Future studies are needed to test whether obesity predicts response to salvage therapies.
Source: BJU International - November 16, 2018 Category: Urology & Nephrology Authors: Stephen J. Freedland, Brandee L. Branche, Lauren E. Howard, Robert J. Hamilton, William J. Aronson, Martha K. Terris, Matthew R. Cooperberg, Christopher L. Amling, Christopher J. Kane, On behalf of the SEARCH Database Study Group Tags: Original Article Source Type: research

Authorship Order in Medical Education Publications: In Search of Practical Guidance for the Community.
This study describes principles commonly applied to authorship order decisions within the medical education community and educators' opinions about the significance of authorship order. Approach: A questionnaire was developed to ascertain current practices related to authorship decisions. Sixteen items were rated in terms of frequency of actual use and the desirability of the practice using a 4-point rating scale: 1 (never), 2 (sometimes), 3 (often), and 4 (always). Additional questions addressed the perceived significance of authorship order. The last set of questions provided information about respondents' personal and c...
Source: Teaching and Learning in Medicine - December 15, 2018 Category: Universities & Medical Training Authors: Authorship Order in Medical Education Publications: In Search of Practical Guidance for the Community. Tags: Teach Learn Med Source Type: research

Planting Trees, Search Engines, and Climate Change
Written by César Palacios-González The other day I went down an internet rabbit hole when researching about planting trees and climate change. I came out the other side concluding (among other things) that there were good reasons to change my search engine to Ecosia[1]. So I did, and, other things being equal, you should too. […]
Source: blog.bioethics.net - August 7, 2019 Category: Medical Ethics Authors: César Palacios-González Tags: Health Care climate change Planting Trees Search Engines syndicated Uncategorized Source Type: blogs

Effective Job Search Strategies to Consider
Before you begin a job search, you need to think through the question, “What’s your strategy as an executive job seeker?” There’s no right or wrong answer to the question, and sometimes it takes trial and error to truly figure out what the most effective strategy is for you. Even then, adjustments must be made […]
Source: EMR and HIPAA - September 5, 2019 Category: Information Technology Authors: Erin Kennedy Tags: Career and Jobs Healthcare IT employment Erin Kennedy Executive Resume Writer executive resumes job search LinkedIn LinkedIn Profile Development Professional Resume Services resume writing Source Type: blogs

Finding the best-fit background function for whole-powder-pattern fitting using LASSO combined with tree search
A new linear function for modelling the background in whole-powder-pattern fitting has been derived by applying LASSO (least absolute shrinkage and selection operator) and the technique of tree search. The background function (BGF) consists of terms bnL(2 θ /180) − n/2   and bnH(1   −   2 θ /180) − n/2 for the low- and high-angle sides, respectively. Some variable parameters of the BGF should be fixed at zero while others should be varied in order to find the best fit for a given data set without inducing overfitting. The LASSO algorithm can automatically select the variables in linear regression analysis. Ho...
Source: Journal of Applied Crystallography - February 14, 2021 Category: Physics Authors: Toraya, H. Tags: background functions LASSO tree search least absolute shrinkage and selection operator whole-powder-pattern fitting X-ray powder diffraction research papers Source Type: research

What is the current best RSS reader?
After it was announced that Google Reader will be shut down in July, some of my Twitter buddies asked me what I plan to use in the future as a RSS reader. I have already switched to RSS Owl. Pros: - faster and more powerful than Google Reader - portable program that does not require installation (choose the version labeled "rssowl-2.1.6.windows.zip"). You can take it on a USB drive if you wish. - keyboard shortcuts - you can either customize the existing shortcuts or create new ones - social media sharing integration (Buffer, Twitter, Facebook, etc.) - Easy export and import of your RSS subscriptions as an OPML file - o...
Source: Clinical Cases and Images - Blog - March 24, 2013 Category: Professors and Educators Tags: RSS Source Type: blogs

Datura suaveolens and Verbena tenuisecta mediated silver nanoparticles, their photodynamic cytotoxic and antimicrobial evaluation
AbstractBiogenic production of nanoparticles is eco-friendly, less expensive method with various medical and biological applications. Nanotechnology along with photodynamic therapy is gaining tremendous importance with enhanced efficacy. The present work was aimed to evaluate methanolic extracts and nanoparticles of two selected plants (Datura suavolens andVerbina tenuisecta) for cytotoxic photodynamic, antioxidant and antimicrobial study. Both extract and silver (5  mM) nanoparticles ofDatura plant showed significant activities against bacterial strains. Maximum ZOI of 27.3  ± 1.6 mm was observed with nanoparticles...
Source: World Journal of Microbiology and Biotechnology - February 10, 2020 Category: Microbiology Source Type: research

Facet ‐Dependent Strain Determination in Electrochemically Synthetized Platinum Model Catalytic Nanoparticles
The uniformity of electrochemically synthesized model catalysts is studied using Bragg Coherent X ‐ray Diffraction Imaging. 3D images of several individual nanoparticles are obtained, assessing their shape and the specific components of the displacement and strain fields both at the surface and inside. A facet recognition algorithm is applied, which provides facet‐dependent structural inform ation for all measured nanoparticles. AbstractStudying model nanoparticles is one approach to better understand the structural evolution of a catalyst during reactions. These nanoparticles feature well ‐defined faceting, offering...
Source: Small - March 19, 2021 Category: Nanotechnology Authors: J érôme Carnis, Lu Gao, Sara Fernández, Gilbert Chahine, Tobias U. Schülli, Stéphane Labat, Emiel J. M. Hensen, Olivier Thomas, Jan P. Hofmann, Marie‐Ingrid Richard Tags: Research Article Source Type: research

Targeted Nanoparticles with High Heating Efficiency for the Treatment of Endometriosis with Systemically Delivered Magnetic Hyperthermia
This study is the first to describe nanoparticles that enable systemically delivered magnetic hyperthermia for endometriosis treatment. When subjected to an alternating magnetic field (AMF), these hexagonal iron-oxide nanoparticles exhibit extraordina ry heating efficiency that is 6.4× greater than their spherical counterparts. Modifying nanoparticles with a peptide targeted to vascular endothelial growth factor receptor 2 (VEGFR-2) enhances their endometriosis specificity. Studies in mice bearing transplants of macaque endometriotic tissue reve al that, following intravenous injection at a low dose (3 mg per kg), these ...
Source: Small - April 18, 2022 Category: Nanotechnology Authors: Youngrong Park, Ananiya A. Demessie, Addie Luo, Olena R. Taratula, Abraham S. Moses, Peter Do, Leonardo Campos, Younes Jahangiri, Cory R. Wyatt, Hassan A. Albarqi, Khashayar Farsad, Ov D. Slayden, Oleh Taratula Tags: Research Article Source Type: research