This page shows you your search results in order of relevance. This is page number 13.

Order by Relevance | Date

Total 4543034 results found since Jan 2013.

The potential effectiveness of nanoparticles as radio sensitizers for radiotherapy.
CONCLUSION: Literature suggests potency of nanoparticles for increasing cell radio sensitivity. Reviewed results are promising and warrant future clinical trials. PMID: 24790894 [PubMed]
Source: BioImpacts - December 13, 2015 Category: Research Tags: Bioimpacts Source Type: research

Sulfur and sulfur nanoparticles as potential antimicrobials: from traditional medicine to nanomedicine.
Authors: Rai M, Ingle AP, Paralikar P Abstract INTRODUCTION: The alarming rate of infections caused by various pathogens and development of their resistance towards a large number of antimicrobial agents has generated an essential need to search for novel and effective antimicrobial agents. Metal nanoparticles such as silver have been widely used and accepted as strong antimicrobial agents, but considering the cost effectiveness and significant bioactivities, researchers are looking to utilize sulfur nanoparticles as an effective alternative to silver nanoparticles. AREAS COVERED: This review has been focused o...
Source: Expert Review of Anti-Infective Therapy - August 9, 2016 Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research

Miltefosine-loaded lipid nanoparticles: Improving miltefosine stability and reducing its hemolytic potential toward erythtocytes and its cytotoxic effect on macrophages.
Abstract The toxic effects of miltefosine on the epithelial cells of the gastrointestinal tract and its hemolytic action on erythrocytes have limited its use as an antileishmanial agent. As part of our search for new strategies to overcome the side effects of miltefosine during the treatment of leishmaniasis, we have developed stable miltefosine-loaded lipid nanoparticles in an attempt to reduce the toxic effects of the drug. We have evaluated lipid nanoparticles containing varying amounts of miltefosine and cholesterol, prepared by sonication, in terms of their physicochemical properties, preliminary stability, h...
Source: Biophysical Chemistry - July 27, 2016 Category: Chemistry Authors: da Gama Bitencourt JJ, Pazin WM, Ito AS, Barioni MB, de Paula Pinto C, Santos MA, Guimarães TH, Santos MR, Valduga CJ Tags: Biophys Chem Source Type: research

Biocompatible silver nanoparticles prepared with amino acids and a green method.
Abstract The synthesis of nanoparticles is usually carried out by chemical reduction, which is effective but uses many toxic substances, making the process potentially harmful to the environment. Hence, as part of the search for environmentally friendly or green synthetic methods, this study aimed to produce silver nanoparticles (AgNPs) using only AgNO3, Milli-Q water, white light from a xenon lamp (Xe) and amino acids. Nanoparticles were synthetized using 21 amino acids, and the shapes and sizes of the resultant nanoparticles were evaluated. The products were characterized by UV-Vis, zeta potential measurements a...
Source: Amino Acids - November 27, 2016 Category: Biochemistry Authors: de Matos RA, Courrol LC Tags: Amino Acids Source Type: research

Phytochemicals Formulated as Nanoparticles: Inventions,Recent Patents and Future Prospects.
CONCLUSION: If bioavailability constraint is overcome, diseases like cancer, alzheimer, diabetes, liver disorder etc. can be effectively targeted. By doing so, the largely affected society, will breathe the relief. The present article is an attempt to elaborate and conclude on how nanoparticles have been serving as a tool to enhance the effectiveness of phytochemicals, by solubilization, dissolution and consequent bioavailability enhancements, along with in vivo targeting. To further facilitate understanding, the review has been structured as disease/disorder and phytochemical wise with focus on their nanoparticles. PM...
Source: Recent Patents on Drug Delivery and Formulation - November 24, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

IJERPH, Vol. 15, Pages 1037: Clinical Efficacy Associated with Enhanced Antioxidant Enzyme Activities of Silver Nanoparticles Biosynthesized Using Moringa oleifera Leaf Extract, Against Cutaneous Leishmaniasis in a Murine Model of Leishmania major
In conclusion, treatment with silver nanoparticles biosynthesized using Moringa oleifera extract has higher and faster clinical efficacy than standard pentavalent antimonial treatment, probably by boosting the endogenous antioxidant activity.
Source: International Journal of Environmental Research and Public Health - May 22, 2018 Category: Environmental Health Authors: Manal El-khadragy Ebtesam M. Alolayan Dina M. Metwally Mohamed F. Serag El-Din Sara S. Alobud Nour I. Alsultan Sarah S. Alsaif Manal A. Awad Ahmed E. Abdel Moneim Tags: Article Source Type: research

Gold-Based Nanoparticles Systems in Phototherapy - Current Strategies.
CONCLUSION: In this work, we show numerous medically and chemically important development strategies of hybrid types of drugs which can be used in phototherapy. These systems have a high affinity to the tumor cells surface proteins which transport the nanoparticles directly into a cell. The application of functionalized metallic nanoparticles in phototherapy improved photophysical properties, lowered cytotoxicity of common used photosensitizers and facilitated the development of the third generation photosensitizers. Furthermore, this type of nanoparticles could also be used as a cytostatic drug carrier in the chemo or com...
Source: Current Medicinal Chemistry - October 31, 2018 Category: Chemistry Authors: Blaszkiewicz P, Kotkowiak M Tags: Curr Med Chem Source Type: research

Evaluation of biological synthesized platinum nanoparticles using Ononidis radix extract on the cell lung carcinoma A549.
Abstract Due to the search for new methods for synthesizing nanomaterials, this work proposes the biological synthesis of platinum nanoparticles using Ononidis radix extract. The synthesized platinum nanoparticles were characterized by UV-Vis, Scanning Electron Microscopy (SEM) with EDS profile, Fourier transform infrared spectroscopy (FTIR), Transmission Electron Microscopy (TEM) and Atomic Force Microscopy (AFM). The examination conducted by means of Transmission Electron Microscopy showed the presence of spherical and hexagonal platinum nanoparticles. Atomic Force Microscopy indicated the presence of locally ag...
Source: Biomedical Microdevices - July 24, 2019 Category: Biomedical Engineering Authors: Dobrucka R, Romaniuk-Drapała A, Kaczmarek M Tags: Biomed Microdevices Source Type: research

Evaluation of Larvicidal Efficacy of Ricinus communis (Castor) Plant Extract and Synthesized Green Silver Nanoparticles against Aedes albopictus.
Conclusion: Our results suggest the extract of R. communis and synthesized nanoparticles as excellent replacement of chemical pesticides to control the vector mosquitoes. PMID: 33365344 [PubMed]
Source: Iranian Journal of Arthropod-Borne Diseases - December 30, 2020 Category: Infectious Diseases Tags: J Arthropod Borne Dis Source Type: research

Nanoparticles in pregnancy: the next frontier in reproductive therapeutics
AbstractBACKGROUNDNanotechnology involves the engineering of structures on a molecular level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic agents to a target site or organ in a controlled manner, maximizing efficacy while minimizing off-target effects of the therapeutic agent administered. In both reproductive medicine and obstetrics, developing innovative therapeutics is often tempered by fears of damage to the gamete, embryo or developing foetus or of negatively impacting a woman ’s reproductive potential. Thus, nanomedicine delivery systems may provide alternative targeted intervent...
Source: Human Reproduction Update - December 6, 2020 Category: OBGYN Source Type: research

Applications of Gold and Silver Nanoparticles in the Treatment of Acne Vulgaris: A Systematic Review
CONCLUSION: This review found gold and silver nanoparticles to be a promising treatment for acne vulgaris. Further randomized controlled studies are needed to determine clinical efficacy and the role of gold and silver nanoparticles in the treatment algorithm for acne. J Drugs Dermatol. 2021;20(6):666-670. doi:10.36849/JDD.5762.PMID:34076399 | DOI:10.36849/JDD.2021.5762
Source: Journal of Drugs in Dermatology - June 2, 2021 Category: Dermatology Authors: Kimberly Artounian Nour Bundogji Elika Hoss Monica Boen Source Type: research