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Characterizing Physical Properties of Superparamagnetic Nanoparticles in Liquid Phase Using Brownian Relaxation
Superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used as bioimaging contrast agents, heating sources for tumor therapy, and carriers for controlled drug delivery and release to target organs and tissues. These applications require elaborate tuning of the physical and magnetic properties of the SPIONs. The authors present here a search‐coil‐based method to characterize these properties. The nonlinear magnetic response of SPIONs to alternating current magnetic fields induces harmonic signals that contain information of these nanoparticles. By analyzing the phase lag and harmonic ratios in the SPI...
Source: Small - April 1, 2017 Category: Nanotechnology Authors: Kai Wu, Karl Schliep, Xiaowei Zhang, Jinming Liu, Bin Ma, Jian ‐Ping Wang Tags: Full Paper Source Type: research

PVP and PEG doped CuO nanoparticles are more biologically active: Antibacterial, antioxidant, antidiabetic and cytotoxic perspective
Publication date: 1 October 2017 Source:Materials Science and Engineering: C, Volume 79 Author(s): Rabia Javed, Madiha Ahmed, Ihsan ul Haq, Sobia Nisa, Muhammad Zia Search for biologically active nanoparticles is prerequisite for biomedical applications. CuO nanoparticles synthesized by co-precipitation method are capped by polyethylene-glycol (PEG) and polyvinyl-pyrrolidone (PVP) on the surface by simple adsorption. Physical and chemical properties carried out by SEM, XRD and FTIR confirm nanometer in size and efficient capping of PVP and PEG on CuO NPs. Biological assays reveal higher activities of CuO-PEG and CuO-PVP a...
Source: Materials Science and Engineering: C - May 10, 2017 Category: Materials Science Source Type: research

Association of Silver Nanoparticles and Curcumin Solid Dispersion: Antimicrobial and Antioxidant Properties.
The objective of this work was to develop a formulation composed of a thermoresponsive gel-with antimicrobial and antioxidant properties due to the association of AgNps with PVP and PVA polymers. After AgNp synthesis, these were incorporated together with the previously prepared CUR/P407 (1:2) solid dispersion (SD) into a polymer dispersion of 20% P407 (thermosensitive gel). Our results showed that the association between the AgNps with CUR SD demonstrated good antioxidant activity as compared to the standard compound. Measures of MIC showed more efficacy against Gram-negative bacteria (Escherichia coli and Pseudomonas aer...
Source: AAPS PharmSciTech - July 5, 2017 Category: Drugs & Pharmacology Authors: Alves TF, Chaud MV, Grotto D, Jozala AF, Pandit R, Rai M, Dos Santos CA Tags: AAPS PharmSciTech Source Type: research

Ag1Pd1 nanoparticles-reduced graphene oxide as highly efficient and recyclable catalyst for direct aryl C-H ole fination.
Ag1Pd1 nanoparticles-reduced graphene oxide as highly efficient and recyclable catalyst for direct aryl C-H olefination. Chemistry. 2017 Sep 26;: Authors: Hu Q, Liu X, Wang G, Wang F, Li Q, Zhang W Abstract The efficient and selective palladium-catalyzed activation of C-H bonds is of great importance for the construction of diverse bioactive molecules. Despite significant progress, the inability to recycle palladium catalysts and the need for additives impedes the practical applications of these reactions. Here, we report the use of Ag1Pd1 nanoparticles-reduced graphene oxide (Ag1Pd1-rGO) as highly e...
Source: Chemistry - September 26, 2017 Category: Chemistry Authors: Hu Q, Liu X, Wang G, Wang F, Li Q, Zhang W Tags: Chemistry Source Type: research

Injectable calcium phosphate scaffold with iron oxide nanoparticles to enhance osteogenesis via dental pulp stem cells.
In conclusion, it is highly promising to incorporate γIONPs and αIONPs into CPC scaffold for bone tissue engineering, yielding substantially better stem cell attachment, spreading and osteogenic differentiation, and much greater bone mineral synthesis by the seeded cells. Therefore, novel CPC scaffolds containing γIONPs and αIONPs are promising for dental, craniofacial and orthopaedic applications to substantially enhance bone regeneration. PMID: 29355052 [PubMed - as supplied by publisher]
Source: Artificial Cells, Nanomedicine and Biotechnology - January 24, 2018 Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research

Synthesis of Gossypium hirsutum ‐derived silver nanoparticles and their antibacterial efficacy against plant pathogens
A stem extract ofGossypium hirsutum was efficiently used for the synthesis of silver nanoparticles (AgNPs). The AgNPs showed antimicrobial activity against plant pathogens. Malvaceae and Brassicaceae family crops are economically important; however, their production has been markedly decreased in recent years due to various plant pests. Hence, the search for novel classes of efficient biological approaches continues due to unavailability of precise pesticides. The present study was designed to synthesize, characterize and evaluate the efficacy of silver nanoparticles (AgNPs) obtained using stem extract ofGossypium hirsutum...
Source: Applied Organometallic Chemistry - November 19, 2018 Category: Chemistry Authors: Gulamnabi L. Vanti, Vijendra B. Nargund, Basavesha K. N, Rajinikanth Vanarchi, Mahantesh Kurjogi, Sikandar I. Mulla, Suresh Tubaki, Rajashekar R. Patil Tags: FULL PAPER Source Type: research

Diethyldithiocarbamate loaded in beeswax-copaiba oil nanoparticles obtained by solventless double emulsion technique promote promastigote death in vitro
Publication date: Available online 18 December 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Karin Luize Mazur, Paulo Emílio Feuser, Alexsandra Valério, Arthur Poester Cordeiro, Camila Indiani de Oliveira, João Paulo Assolini, Wander Rogério Pavanelli, Claudia Sayer, Pedro H.H. AraújoAbstractLeishmaniasis is considered a neglected tropical disease that represents a Public Health problem due to its high incidence. In the search of new alternatives for Leishmaniasis treatment diethyldithiocarbamate (DETC) has shown an excellent leishmanicidal activity and the incorporation into drug carrier systems, such ...
Source: Colloids and Surfaces B: Biointerfaces - December 25, 2018 Category: Biochemistry Source Type: research

In vitro anthelmintic effect of biologically synthesized silver nanoparticles on liver amphistome, Gigantocotyle explanatum.
Abstract In order to ensure global food security a rationale approach is required to control all those factors which directly or indirectly affect the food productivity. The neglected helminthic diseases alone are responsible for huge economic losses to the agrarian stakeholders. The problem is further compounded by the emerging drug resistance in flukes against the commonly used anthelmintics like triclabendazole. Therefore, the search for alternatives including the nano-based approaches has become a necessity to develop future control strategies. In the present study the effect of biologically synthesized silver...
Source: Experimental Parasitology - February 12, 2019 Category: Parasitology Authors: Rehman A, Ullah R, Uddin I, Zia I, Rehman L, Abidi SMA Tags: Exp Parasitol Source Type: research

Soil bacteria Cupriavidus sp. Mediates the extracellular synthesis of antibacterial silver nanoparticles
Publication date: Available online 15 October 2019Source: Journal of Molecular StructureAuthor(s): F. Ameen, S. AlYahia, M. Govarthanan, N. ALjahdali, N. Al-Enazi, K. Alsamhari, W.A. Alshehri, S.S. Alwakeel, S.A. AlharbiAbstractSilver nanoparticles (AgNPs) were synthesized extracellularly using a bacterium Cuprividus sp., which was isolated from urban soil and assumed be heavy metal resistant. The successful synthesis of nano size (10–50 nm) spherical crystalline particles was shown by microscopic, diffractometric and spectroscopic analyses. Further, the FTIR spectrum of the AgNPs indicated the presence of amides, which ...
Source: Journal of Molecular Structure - October 20, 2019 Category: Molecular Biology Source Type: research

Overview of Synthetic Methods to Prepare Plasmonic Transition Metal Nitride Nanoparticles.
Abstract The search for new plasmonic materials that are low-cost, chemically and thermally stable, and exhibit low optical losses has garnered significant attention among researchers. Recently, metal nitrides have emerged as promising alternatives to conventional, noble metal based plasmonic materials such as Ag and Au. Many of the initial studies on metal nitrides have focused on computational prediction of the material plasmonic properties. In recent years, several synthetic methods have been developed, enabling empirical analysis. This review highlights synthetic techniques for the preparation of plasmonic met...
Source: Chemistry - February 17, 2020 Category: Chemistry Authors: Karaballi RA, Monfared YE, Dasog M Tags: Chemistry Source Type: research

Recovery of immunoglobulin G from rabbit serum using κ-carrageenan-modified hybrid magnetic nanoparticles.
Abstract Immunoglobulin G (IgG) has been used in the treatment of cancer, autoimmune diseases and neurological disorders, however, the current technologies to purify and recover IgG from biological media are of high-cost and time-consuming, resulting in high-cost products. In this sense, the search for cost-effective technologies to obtain highly pure and active IgG is highly required. The present work proposes a simple and efficient method for the purification and recovery of IgG from rabbit serum using magnetic iron oxide nanoparticles (magnetite, Fe3O4) coated with hybrid shells of a siliceous material modified...
Source: International Journal of Biological Macromolecules - February 13, 2020 Category: Biochemistry Authors: Magalhães FF, Almeida MR, Soares SF, Trindade T, Freire MG, Daniel-da-Silva AL, Tavares APM Tags: Int J Biol Macromol Source Type: research

Surface engineered iron oxide nanoparticles as efficient materials for antibiofilm application
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Source: Biotechnology and Applied Biochemistry - March 11, 2021 Category: Biochemistry Authors: Palaniyandi Velusamy, Chia ‐Hung Su, Kiruba Kannan, Govindarajan Venkat Kumar, Periasmy Anbu, Subash C.B. Gopinath Tags: Review Article Source Type: research

Isolation, biosynthesis and antimicrobial activity of gold nanoparticles produced with extracts of Anabaena spiroides
Bioprocess Biosyst Eng. 2021 Mar 11. doi: 10.1007/s00449-021-02544-4. Online ahead of print.ABSTRACTMultidrug-resistant (MDR) pathogenic bacteria have become dangerous in bringing sporadic outbreaks in public health and nosocomial spreads from the addition of antibacterials/antibiotics continually. Obviously, the pharmacy world is in search of antibacterials that would be invincible by the evolved bacteria. Green synthesis of gold-nanoparticles (AuNps) was focused on the use of aqueous chloroauric acid (HAuCl4) and cell-free aqueous extract of the N2-fixing cyanobacterium (blue-green alga) Anabaena spiroides collected from...
Source: Bioprocess and Biosystems Engineering - March 11, 2021 Category: Biomedical Engineering Authors: Chinmayee Priyadarshini Mandhata Chita Ranjan Sahoo Chandrika Saloni Mahanta Rabindra Nath Padhy Source Type: research

Surface engineered iron oxide nanoparticles as efficient materials for antibiofilm application
ABSTRACTOveruse of antibiotics has led to the development of multidrug ‐resistant strains. Antibiotic resistance is a major drawback in the biomedical field since medical implants are prone to infection by biofilms of antibiotic resistant strains of bacteria. With increasing prevalence of antibiotic‐resistant pathogenic bacteria, the search for alternative method i s utmost importance. In this regard, magnetic nanoparticles are commonly used as a substitute for antibiotics that can circumvent the problem of biofilms growth on the surface of biomedical implants. Iron oxide nanoparticles (IONPs) have unique magnetic prop...
Source: Biotechnology and Applied Biochemistry - March 20, 2021 Category: Biochemistry Authors: Palaniyandi Velusamy, Chia ‐Hung Su, Kiruba Kannan, Govindarajan Venkat Kumar, Periasamy Anbu, Subash C.B. Gopinath Tags: REVIEW ARTICLE Source Type: research