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Use of Co < sub > 3 < /sub > O < sub > 4 < /sub > nanoparticles with different surface morphologies for removal of toxic substances and investigation of antimicrobial activities via in vivo studies
Environ Sci Pollut Res Int. 2023 Sep 21. doi: 10.1007/s11356-023-29879-7. Online ahead of print.ABSTRACTCo3O4 nanoparticles (NPs) were formed using hydrothermal synthesis method and various surfactants to study the effect of changing surface morphology on catalytic and antibacterial activities. FT-IR, TEM, SEM, BET, XRD, and XPS analyses were performed to characterize the NPs. It was observed that as the morphology of Co3O4 changes, it creates differences in the reduction efficiency of organic dyes and p-nitrophenol (p-NP), which are toxic to living organisms and widely used in industry. The reaction rate constants (Kapp) ...
Source: Environmental Science and Pollution Research International - September 21, 2023 Category: Environmental Health Authors: Nurdan Kurnaz Yetim Elvan Hasano ğlu Özkan Hatice Öğütçü Source Type: research

Molecules, Vol. 20, Pages 6284-6298: Synthesis, Photophysical Characterization, and Photoinduced Antibacterial Activity of Methylene Blue-loaded Amino- and Mannose-Targeted Mesoporous Silica Nanoparticles
Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial photodynamic therapy (aPDT), also called photodynamic inactivation, is emerging as a promising alternative to treatments based on conventional antibiotics. We have explored the effectiveness of methylene blue-loaded targeted mesoporous silica nanoparticles (MSNP) in the photodynamic inactivation of two Gram negative bacteria, namely Escherichia coli and Pseudomonas aeruginosa. For E. coli, nanoparticle association clearly red...
Source: Molecules - April 9, 2015 Category: Chemistry Authors: Oriol PlanasRoger Bresolí-ObachJaume NosThibault GallavardinRubén Ruiz-GonzálezMontserrat AgutSanti Nonell Tags: Article Source Type: research

IJERPH, Vol. 14, Pages 747: Disinfection of the Water Borne Pathogens Escherichia coli and Staphylococcus aureus by Solar Photocatalysis Using Sonochemically Synthesized Reusable Ag@ZnO Core-Shell Nanoparticles
Water borne pathogens present a threat to human health and their disinfection from water poses a challenge, prompting the search for newer methods and newer materials. Disinfection of the Gram-negative bacterium Escherichia coli and the Gram-positive coccal bacterium Staphylococcus aureus in an aqueous matrix was achieved within 60 and 90 min, respectively, at 35 °C using solar-photocatalysis mediated by sonochemically synthesized Ag@ZnO core-shell nanoparticles. The efficiency of the process increased with the increase in temperature and at 55 °C the disinfection for the two bacteria could be achieved in 45 and 60 min, ...
Source: International Journal of Environmental Research and Public Health - July 10, 2017 Category: Environmental Health Authors: Sourav Das Neha Ranjana Ananyo Jyoti Misra Mrutyunjay Suar Amrita Mishra Ashok J. Tamhankar Cecilia St ålsby Lundborg Suraj K. Tripathy Tags: Article Source Type: research

Antimicrobial and antibiofilm activity of curcumin-silver nanoparticles with improved stability and selective toxicity to bacteria over mammalian cells
AbstractAntibiotic resistance has necessitated search for new antibacterials for combating threat of pathogenic bacteria. Though chemically synthesized silver nanoparticles are a well-known antimicrobial agent, they are toxic to human cells at higher concentrations. Hence in the present study, curcumin-silver nanoparticles (Cur –AgNPs) of size 25–35 nm, were synthesized using curcumin, a phytochemical. These nanoparticles were effective against both Gram positive and Gram-negative bacteria and were less toxic to human keratinocytes. They had very low total silver content and high stability. The antibacterial activity ...
Source: Medical Microbiology and Immunology - October 28, 2017 Category: Microbiology Source Type: research

Exosome-Like Nanoparticles: A New Type Of Nanocarrier.
Abstract Nanoparticles are one of the most used systems for imaging or therapeutic drug delivery. Exosomes are nanovesicular carriers that transport cargo for intercellular communication. These nanovesicles are linked to the pathology of some major diseases, in some cases with a central role in their progression. The use of these carriers to transport therapeutic drugs is a recent and promising approach to treat diseases such as cancer and Alzheimer disease. The physiological production of these structures is limited impairing its collection and subsequent purification. These drawbacks inspired the search for mime...
Source: Current Medicinal Chemistry - January 29, 2019 Category: Chemistry Authors: Fernandes M, Lopes I, Teixeira J, Botelho C, Gomes AC Tags: Curr Med Chem Source Type: research

Assessment of the structural reorganization of liver and biochemical parameters of blood serum after introduction of zinc nanoparticles and its oxides.
Abstract The demand for nanoparticles of metals and their oxides in medicine and biology is indisputable. To ensure the safe use of the unique capabilities of nanostructures, in particular, essential metals and their oxides, and to further search for ways leveling side effects of toxic effects in biomedical applications, a multifaceted approach to the study of their properties is needed, primarily affecting the effects on the organism level. In this connection, the purpose of the present research was to study the effect of zinc nanoparticles (ZnNPs) and zinc oxide nanoparticles (ZnONPs) on structural reorganizatio...
Source: Environmental Science and Pollution Research International - April 17, 2019 Category: Environmental Health Authors: Sizova E, Miroshnikov S, Nechitailo X Tags: Environ Sci Pollut Res Int Source Type: research

Importance of radiolytic reactions during high-LET irradiation modalities: LET effect, role of O 2 and radiosensitization by nanoparticles
This article reviews radiation chemistry processes induced by high-linear energy transfer (LET) radiation. The first part gives a short historical introduction and defines the essential concepts of radiation chemistry. It is aimed at radiobiologists in search of basics in this discipline, to link to their biological observations. Then, special focus is done on LET effect, oxygen effect and nanoparticles as these parameters can influence the success of radiotherapy. The embraced point of view is the one from a chemist as involved molecular reactions in water are detailed and revealed, for example, how dioxygen can be produc...
Source: Cancer Nanotechnology - May 12, 2019 Category: Cancer & Oncology Source Type: research

Sensors, Vol. 22, Pages 3639: The Influence of Air Humidity on the Output Signal from an Ionization Smoke Detector in the Presence of Soot Nanoparticles
ubiak In 2019, the European Committee for Standardization (CEN) initiated work on the preparation of a strategy for air quality monitoring at workplaces. The aim was to determine the concentrations of nano-objects and their aggregates and agglomerates (NOAA) by means of direct measurements using low-cost sensors. There is a growing need for low-cost devices that can continuously monitor the concentrations of nanoparticles, and that can be installed where nanoparticles are used or created spontaneously. In search of such a device, in this study, a smoke detector with an ionization sensor was tested. The aim of the resea...
Source: Sensors - May 10, 2022 Category: Biotechnology Authors: Tomasz Jankowski Piotr Sobiech Szymon Jakubiak Tags: Article Source Type: research

Elimination of Enterococcus faecalis from root canal system using laser-activated nanoparticles: a systematic review
AbstractElimination of Enterococcus faecalis is vital during root canal treatment. Owing to their antimicrobial properties, laser-activated nanoparticles (NPs) have been used in root canal irrigation in the recent past. The aim of this review is to conduct a qualitative analysis of the published data evaluating the antibacterial efficacy of laser-activated nanoparticles in the elimination of E. faecalis from the root canal system. Considering all the papers published till August 2022, a search of the databases PubMed, SCOPUS, and EBSCOhost was conducted. All the articles that were published in English were included. The re...
Source: Lasers in Medical Science - March 1, 2023 Category: Laser Surgery Source Type: research

Health implications of engineered nanoparticles in infants and children.
CONCLUSIONS: As the manufacturing and use of ENPs become more widespread, directed and focused studies are necessary to measure actual exposure levels and to determine adverse health consequences in infants and children. PMID: 26253410 [PubMed - in process]
Source: World Journal of Pediatrics : WJP - August 1, 2015 Category: Pediatrics Authors: Tang S, Wang M, Germ KE, Du HM, Sun WJ, Gao WM, Mayer GD Tags: World J Pediatr Source Type: research

Zinc oxide and titanium dioxide nanoparticles induce oxidative stress, inhibit growth, and attenuate biofilm formation activity of Streptococcus mitis.
Abstract Streptococcus mitis from the oral cavity causes endocarditis and other systemic infections. Rising resistance against traditional antibiotics amongst oral bacteria further aggravates the problem. Therefore, antimicrobial and antibiofilm activities of zinc oxide and titanium dioxide nanoparticles (NPs) synthesized and characterized during this study against S. mitis ATCC 6249 and Ora-20 were evaluated in search of alternative antimicrobial agents. ZnO and TiO2-NPs exhibited an average size of 35 and 13 nm, respectively. The IC50 values of ZnO and TiO2-NPs against S. mitis ATCC 6249 were 37 and 77 µg ml...
Source: Journal of Biological Inorganic Chemistry : JBIC - February 2, 2016 Category: Chemistry Authors: Khan ST, Ahmad J, Ahamed M, Musarrat J, Al-Khedhairy AA Tags: J Biol Inorg Chem Source Type: research

Countering drug resistance, infectious diseases, and sepsis using metal and metal oxides nanoparticles: Current status.
Abstract One fourth of the global mortalities is still caused by microbial infections largely due to the development of resistance against conventional antibiotics among pathogens, the resurgence of old infectious diseases and the emergence of hundreds of new infectious diseases. The lack of funds and resources for the discovery of new antibiotics necessitates the search for economic and effective alternative antimicrobial agents. Metal and metal oxide nanoparticles including silver and zinc oxide exhibit remarkable antimicrobial activities against pathogens and hence are one of the most propitious alternative ant...
Source: Colloids and Surfaces - May 17, 2016 Category: Biotechnology Authors: Khan ST, Musarrat J, Al-Khedhairy AA Tags: Colloids Surf B Biointerfaces Source Type: research

Odyssey in Polyphasic Catalysis by Metal Nanoparticles.
Abstract Nanometer-sized metal particles constitute an unavoidable family of catalysts, combining the advantages of molecular complexes in regards to their catalytic performances and the ones of heterogeneous systems in terms of easy recycling. As part of this research, our group aims at designing well-defined metal nanoparticles based-catalysts, in non-conventional media (ionic liquids or water), for various catalytic applications (hydrogenation, dehalogenation, carbon-carbon coupling, asymmetric catalysis) in mild reaction conditions. In the drive towards a more eco-responsible chemistry, the main focuses rely o...
Source: Chemical Record - July 17, 2016 Category: Chemistry Authors: Denicourt-Nowicki A, Roucoux A Tags: Chem Rec Source Type: research

Synergistic antimicrobial potential of essential oils in combination with nanoparticles: Emerging trends and future perspectives
Publication date: 15 March 2017 Source:International Journal of Pharmaceutics, Volume 519, Issues 1–2 Author(s): Mahendra Rai, Priti Paralikar, Priti Jogee, Gauravi Agarkar, Avinash P. Ingle, Marcos Derita, Susana Zacchino The development of resistance to different antimicrobial agents by bacteria, fungi, viruses, parasites, etc. is a great challenge to the medical field for the treatment of infections caused by them, and therefore, there is a pressing need to search for new and novel antimicrobials. The antimicrobial activity of essential oils and biogenic nanoparticles is well known. Recent studies have demonstrated t...
Source: International Journal of Pharmaceutics - January 15, 2017 Category: Drugs & Pharmacology Source Type: research

Nanoparticles generated from a tryptophan derivative: physical characterization and anti-cancer drug delivery.
Abstract Surging reports of peptide-based nanosystems and their growing potency in terms of biological utility demand for the search of newer and simpler peptide-based systems that could serve as smart templates for the development of self-assembled nanostructures. Use of simple amino acids as monomeric building blocks for synthesizing ensembles of nanostructures have gained momentum in this direction with some reports focusing on the development of nanosystems from single or modified single amino acids. In this work, we have demonstrated self-assembly and nanoparticle formation ability of a single amino acid deri...
Source: Amino Acids - March 9, 2017 Category: Biochemistry Authors: Dube T, Mandal S, Panda JJ Tags: Amino Acids Source Type: research